ZA908599B - A method for isolating biologically active compounds - Google Patents

A method for isolating biologically active compounds

Info

Publication number
ZA908599B
ZA908599B ZA908599A ZA908599A ZA908599B ZA 908599 B ZA908599 B ZA 908599B ZA 908599 A ZA908599 A ZA 908599A ZA 908599 A ZA908599 A ZA 908599A ZA 908599 B ZA908599 B ZA 908599B
Authority
ZA
South Africa
Prior art keywords
biologically active
active compounds
isolating biologically
isolating
factor viii
Prior art date
Application number
ZA908599A
Other languages
English (en)
Inventor
Per Kaersgaard
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of ZA908599B publication Critical patent/ZA908599B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Amplifiers (AREA)
  • Networks Using Active Elements (AREA)
  • Housing For Livestock And Birds (AREA)
  • Cephalosporin Compounds (AREA)
  • External Artificial Organs (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Separation By Low-Temperature Treatments (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
ZA908599A 1989-11-09 1990-10-26 A method for isolating biologically active compounds ZA908599B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK562189A DK162233C (da) 1989-11-09 1989-11-09 Fremgangsmaade til isolering af faktor viii fra blodplasma og pharmaceutisk praeparat indeholdende den saaledes isolerede fator viii

Publications (1)

Publication Number Publication Date
ZA908599B true ZA908599B (en) 1991-07-31

Family

ID=8144000

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA908599A ZA908599B (en) 1989-11-09 1990-10-26 A method for isolating biologically active compounds

Country Status (26)

Country Link
US (1) US5245014A (fr)
EP (1) EP0524172B1 (fr)
JP (1) JP2509407B2 (fr)
CN (1) CN1044121C (fr)
AT (1) ATE118508T1 (fr)
AU (1) AU631471B2 (fr)
BG (1) BG61231B1 (fr)
CA (1) CA2073012C (fr)
CZ (1) CZ537190A3 (fr)
DE (1) DE69017050T2 (fr)
DK (1) DK162233C (fr)
ES (1) ES2068404T3 (fr)
FI (1) FI103510B1 (fr)
HU (1) HU214905B (fr)
IE (1) IE66836B1 (fr)
IL (1) IL96277A (fr)
NO (1) NO180741C (fr)
NZ (1) NZ236004A (fr)
PL (1) PL164894B1 (fr)
PT (1) PT95830B (fr)
RU (1) RU2055593C1 (fr)
SK (1) SK537190A3 (fr)
UA (1) UA29421C2 (fr)
WO (1) WO1991007438A1 (fr)
YU (1) YU47524B (fr)
ZA (1) ZA908599B (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2042138T3 (es) * 1989-05-24 1993-12-01 Miles Inc. Filtracion en gel del factor viii tratado termicamente.
US5859204A (en) * 1992-04-07 1999-01-12 Emory University Modified factor VIII
US6180371B1 (en) 1996-06-26 2001-01-30 Emory University Modified factor VIII
US5888974A (en) * 1992-04-07 1999-03-30 Emory University Hybrid human/animal factor VIII
US5659017A (en) * 1995-11-07 1997-08-19 Alpha Therapeutic Corporation Anion exchange process for the purification of Factor VIII
US7560107B2 (en) 1996-06-26 2009-07-14 Emory University Modified factor VIII
US6458563B1 (en) 1996-06-26 2002-10-01 Emory University Modified factor VIII
US6531577B1 (en) * 1997-12-15 2003-03-11 Hemasure Denmark A/S von Willebrand factor (vWF)-containing preparation, process for preparing vWF-containing preparations, and use of such preparations
US6290527B1 (en) * 1998-07-03 2001-09-18 Nippon Telegraph And Telephone Corp. Nippon telegraph and telephone corporation
US6586573B1 (en) 1999-02-22 2003-07-01 Baxter International Inc. Albumin-free Factor VIII formulations
JP2002348300A (ja) * 1999-04-12 2002-12-04 Fujimori Kogyo Co Ltd 血液凝固第ｖｉｉｉ因子および血液凝固第ｖｉｉｉ因子／フォン・ビルブラント因子複合体の精製方法
AUPR638801A0 (en) * 2001-07-13 2001-08-09 Life Therapeutics Limited Factor viii separation
ES2449044T3 (es) 2004-05-03 2014-03-18 Emory University Procedimiento de administración de fVIII sin dominio B porcino
CN101010333B (zh) * 2004-08-27 2013-08-14 诺和诺德医疗保健公司 从生物材料中纯化凝血因子xⅲ多肽
US20060226086A1 (en) * 2005-04-08 2006-10-12 Robinson Thomas C Centrifuge for blood processing systems
AU2009313325B2 (en) * 2008-11-07 2014-05-01 Takeda Pharmaceutical Company Limited Factor VIII formulations
BR112012024550B1 (pt) * 2010-03-30 2020-12-08 Octapharma Ag processo de produção de uma proteína dependente de vitamina k livre de príons em uma sequência de purificação que emprega cromatografia
RU2445974C2 (ru) * 2010-04-26 2012-03-27 Учреждение Российской академии медицинских наук Гематологический научный центр ГНЦ РАМН Способ получения концентрата фактора viii из плазмы крови человека
KR101948337B1 (ko) 2010-11-05 2019-02-14 박스알타 인코퍼레이티드 증가된 특이 활성도를 갖는 항혈우병 인자 ｖｉｉｉ의 신규 변이체
CA2821711C (fr) 2010-12-15 2017-10-10 Baxter International Inc. Recuperation d'eluat par utilisation d'un gradient de conductivite
CN103506080A (zh) * 2012-06-19 2014-01-15 汪志友 一种用于分离纯化凝血因子viii的介质及其制备方法
CA2886326C (fr) * 2012-09-28 2021-11-02 Chugai Seiyaku Kabushiki Kaisha Procede d'evaluation de reaction de coagulation du sang
US9663553B2 (en) 2014-01-29 2017-05-30 Hemarus Therapeutics Limited Integrated process for the production of therapeutics (human albumin, immunoglobulins, clotting factor VIII and clotting factor IX) from human plasma

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4495175A (en) * 1982-08-05 1985-01-22 University Of Rochester Preparation of highly purified human antihemophilic factor
US4543210A (en) * 1984-10-04 1985-09-24 Miles Laboratories, Inc. Process for producing a high purity antihemophilic factor concentrate
DK525384D0 (da) * 1984-11-05 1984-11-05 Nordisk Insulinlab Praeparat paa basis af faktor viii til behandling af haemofili a inhibitorpatienter samt fremgangsmaade til fremstilling af et saadan praeparat
US4847362A (en) * 1985-02-01 1989-07-11 New York University Method for purifying antihemophilic factor
US4675385A (en) * 1985-03-27 1987-06-23 Alpha Therapeutic Corporation Isolation of human plasma procoagulant protein factor VIII from biological factors
US4758657A (en) * 1985-07-11 1988-07-19 Armour Pharmaceutical Company Method of purifying Factor VIII:C
AT391808B (de) * 1986-11-03 1990-12-10 Immuno Ag Verfahren zur herstellung einer faktor viii (ahf)-haeltigen fraktion
ATE112287T1 (de) * 1987-12-21 1994-10-15 Miles Inc Faktor viii- gelfiltration.
WO1989009784A1 (fr) * 1988-04-08 1989-10-19 Commonwealth Serum Laboratories Commission Production de concentre de facteur viii thermostable
ES2042138T3 (es) * 1989-05-24 1993-12-01 Miles Inc. Filtracion en gel del factor viii tratado termicamente.

Also Published As

Publication number Publication date
HUT60511A (en) 1992-09-28
DK162233B (da) 1991-09-30
WO1991007438A1 (fr) 1991-05-30
FI103510B (fi) 1999-07-15
FI103510B1 (fi) 1999-07-15
IE904022A1 (en) 1991-05-22
IL96277A0 (en) 1991-08-16
DK562189A (da) 1991-05-10
DE69017050T2 (de) 1995-06-14
ES2068404T3 (es) 1995-04-16
NO180741C (no) 1997-06-11
EP0524172B1 (fr) 1995-02-15
PT95830B (pt) 1997-11-28
CA2073012A1 (fr) 1991-05-10
HU9201551D0 (en) 1992-08-28
NO180741B (no) 1997-03-03
YU47524B (sh) 1995-10-03
DK162233C (da) 1992-03-16
HU214905B (hu) 1998-07-28
CN1044121C (zh) 1999-07-14
CN1051732A (zh) 1991-05-29
DE69017050D1 (de) 1995-03-23
NO921839L (no) 1992-07-08
JP2509407B2 (ja) 1996-06-19
DK562189D0 (da) 1989-11-09
NO921839D0 (no) 1992-05-08
BG96316A (bg) 1993-12-24
SK278640B6 (en) 1997-12-10
PL287703A1 (en) 1991-12-02
FI922105A0 (fi) 1992-05-08
SK537190A3 (en) 1997-12-10
US5245014A (en) 1993-09-14
BG61231B1 (en) 1997-03-31
AU6747090A (en) 1991-06-13
IE66836B1 (en) 1996-02-07
CZ537190A3 (cs) 1998-05-13
PL164894B1 (pl) 1994-10-31
JPH05501557A (ja) 1993-03-25
UA29421C2 (uk) 2000-11-15
YU210590A (sh) 1993-05-28
RU2055593C1 (ru) 1996-03-10
PT95830A (pt) 1991-09-30
CA2073012C (fr) 1996-03-19
EP0524172A1 (fr) 1993-01-27
AU631471B2 (en) 1992-11-26
NZ236004A (en) 1991-11-26
FI922105A (fi) 1992-05-08
IL96277A (en) 1995-07-31
ATE118508T1 (de) 1995-03-15

Similar Documents

Publication Publication Date Title
IL96277A0 (en) Method for isolating biologically active compounds
AU580975B2 (en) Osteogenic factors
NZ218913A (en) Process for separating components of natural gas
AU5378686A (en) Process for the extraction and purification of proteins from culture media producing them
ES2000030A6 (es) Metodo de purificar factor sanguineo viii:c
NO174105C (no) Analogifremgangsmåte for fremstilling av antikoagulerende peptider
HU895859D0 (en) Process for separating of foline acid
AU575496B2 (en) Porous membrane for separation of blood components and method for manufacture thereof
EP0424975A3 (en) Artificial carrier for immobilization of biological proteins and process for production thereof
GB2218991B (en) Enzymatic membrane method for the synthesis of peptides and the separation of optical isomers
AU582497B2 (en) Improved process for separation of acid gases
EP0256812A3 (en) Process for separation of n-protected -alpha-l-aspartyl-l-phenylalines
AU5024490A (en) Method of recovering purified epi protein from a solution especially a fermentation solution
AU1885688A (en) Apparatus for separation of blood
AU1929188A (en) Process for recovery of gold
HU203715B (en) Process for separating optically active isomeres of cys-free trans chrisanthemic acid
KR920701461A (ko) 펩티드의 합성 및 분리를 위한 효소막법
LV10690B (en) Method for separation of blood proteins
CS390888A1 (en) Method of purified allergens preparation from materials of biological origin
HK50691A (en) Enzymatic membrane method for the synthesis of peptides and the separation of optical isomers
BG44094A1 (en) Method for separating of furfurol from hydrolysate
DK690587A (da) Tetrapeptid, dets fremstilling og anvendelse
SU1505190A3 (ru) СПОСОБ ОПРЕДЕЛЕНИЯ НАРУШЕНИЙ СИНТЕЗА β -ЦЕПЕЙ ГЛОБИНА В КЛЕТКАХ КОСТНОГО МОЗГА БОЛЬНЫХ b -ТАЛАССЕМИЕЙ