NO180741C - Fremgangsmåte for isolering av Faktor VIII - Google Patents

Fremgangsmåte for isolering av Faktor VIII

Info

Publication number
NO180741C
NO180741C NO921839A NO921839A NO180741C NO 180741 C NO180741 C NO 180741C NO 921839 A NO921839 A NO 921839A NO 921839 A NO921839 A NO 921839A NO 180741 C NO180741 C NO 180741C
Authority
NO
Norway
Prior art keywords
factor viii
isolating factor
isolating
proteins
plasma
Prior art date
Application number
NO921839A
Other languages
English (en)
Other versions
NO921839L (no
NO180741B (no
NO921839D0 (no
Inventor
Per Kaersgaard
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of NO921839D0 publication Critical patent/NO921839D0/no
Publication of NO921839L publication Critical patent/NO921839L/no
Publication of NO180741B publication Critical patent/NO180741B/no
Publication of NO180741C publication Critical patent/NO180741C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Amplifiers (AREA)
  • Networks Using Active Elements (AREA)
  • External Artificial Organs (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Separation By Low-Temperature Treatments (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
NO921839A 1989-11-09 1992-05-08 Fremgangsmåte for isolering av Faktor VIII NO180741C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK562189A DK162233C (da) 1989-11-09 1989-11-09 Fremgangsmaade til isolering af faktor viii fra blodplasma og pharmaceutisk praeparat indeholdende den saaledes isolerede fator viii
PCT/DK1990/000279 WO1991007438A1 (en) 1989-11-09 1990-11-05 A method for isolating factor viii

Publications (4)

Publication Number Publication Date
NO921839D0 NO921839D0 (no) 1992-05-08
NO921839L NO921839L (no) 1992-07-08
NO180741B NO180741B (no) 1997-03-03
NO180741C true NO180741C (no) 1997-06-11

Family

ID=8144000

Family Applications (1)

Application Number Title Priority Date Filing Date
NO921839A NO180741C (no) 1989-11-09 1992-05-08 Fremgangsmåte for isolering av Faktor VIII

Country Status (26)

Country Link
US (1) US5245014A (no)
EP (1) EP0524172B1 (no)
JP (1) JP2509407B2 (no)
CN (1) CN1044121C (no)
AT (1) ATE118508T1 (no)
AU (1) AU631471B2 (no)
BG (1) BG61231B1 (no)
CA (1) CA2073012C (no)
CZ (1) CZ537190A3 (no)
DE (1) DE69017050T2 (no)
DK (1) DK162233C (no)
ES (1) ES2068404T3 (no)
FI (1) FI103510B (no)
HU (1) HU214905B (no)
IE (1) IE66836B1 (no)
IL (1) IL96277A (no)
NO (1) NO180741C (no)
NZ (1) NZ236004A (no)
PL (1) PL164894B1 (no)
PT (1) PT95830B (no)
RU (1) RU2055593C1 (no)
SK (1) SK278640B6 (no)
UA (1) UA29421C2 (no)
WO (1) WO1991007438A1 (no)
YU (1) YU47524B (no)
ZA (1) ZA908599B (no)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2042138T3 (es) * 1989-05-24 1993-12-01 Miles Inc. Filtracion en gel del factor viii tratado termicamente.
US5859204A (en) * 1992-04-07 1999-01-12 Emory University Modified factor VIII
US5888974A (en) * 1992-04-07 1999-03-30 Emory University Hybrid human/animal factor VIII
US6180371B1 (en) 1996-06-26 2001-01-30 Emory University Modified factor VIII
US5659017A (en) * 1995-11-07 1997-08-19 Alpha Therapeutic Corporation Anion exchange process for the purification of Factor VIII
US7560107B2 (en) 1996-06-26 2009-07-14 Emory University Modified factor VIII
US6458563B1 (en) 1996-06-26 2002-10-01 Emory University Modified factor VIII
US6531577B1 (en) * 1997-12-15 2003-03-11 Hemasure Denmark A/S von Willebrand factor (vWF)-containing preparation, process for preparing vWF-containing preparations, and use of such preparations
US6290527B1 (en) * 1998-07-03 2001-09-18 Nippon Telegraph And Telephone Corp. Nippon telegraph and telephone corporation
RU2244556C2 (ru) 1999-02-22 2005-01-20 Юниверсити Оф Коннектикут Новые не содержащие альбумин составы фактора viii
JP2002348300A (ja) * 1999-04-12 2002-12-04 Fujimori Kogyo Co Ltd 血液凝固第ｖｉｉｉ因子および血液凝固第ｖｉｉｉ因子／フォン・ビルブラント因子複合体の精製方法
AUPR638801A0 (en) * 2001-07-13 2001-08-09 Life Therapeutics Limited Factor viii separation
EP1750733B1 (en) 2004-05-03 2013-12-11 Emory University METHOD OF ADMINISTERING PORCINE B-DOMAINLESS fVIII
CN101010333B (zh) * 2004-08-27 2013-08-14 诺和诺德医疗保健公司 从生物材料中纯化凝血因子xⅲ多肽
US20060226086A1 (en) * 2005-04-08 2006-10-12 Robinson Thomas C Centrifuge for blood processing systems
JP5779780B2 (ja) 2008-11-07 2015-09-16 バクスター・インターナショナル・インコーポレイテッドＢａｘｔｅｒ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｉｎｃｏｒｐ０Ｒａｔｅｄ 第ｖｉｉｉ因子製剤
JP5876868B2 (ja) * 2010-03-30 2016-03-02 オクタファルマ・アーゲー 第ｉｘ凝固因子などのビタミンｋ依存性タンパク質の精製方法
RU2445974C2 (ru) * 2010-04-26 2012-03-27 Учреждение Российской академии медицинских наук Гематологический научный центр ГНЦ РАМН Способ получения концентрата фактора viii из плазмы крови человека
SG10201509149VA (en) 2010-11-05 2015-12-30 Baxter Int A new variant of antihemophilic factor viii having increased specific activity
US9488625B2 (en) 2010-12-15 2016-11-08 Baxalta GmbH Purification of factor VIII using a conductivity gradient
CN103506080A (zh) * 2012-06-19 2014-01-15 汪志友 一种用于分离纯化凝血因子viii的介质及其制备方法
TWI609083B (zh) 2012-09-28 2017-12-21 Chugai Pharmaceutical Co Ltd Blood coagulation reaction assessment method
US9663553B2 (en) 2014-01-29 2017-05-30 Hemarus Therapeutics Limited Integrated process for the production of therapeutics (human albumin, immunoglobulins, clotting factor VIII and clotting factor IX) from human plasma

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4495175A (en) * 1982-08-05 1985-01-22 University Of Rochester Preparation of highly purified human antihemophilic factor
US4543210A (en) * 1984-10-04 1985-09-24 Miles Laboratories, Inc. Process for producing a high purity antihemophilic factor concentrate
DK525384D0 (da) * 1984-11-05 1984-11-05 Nordisk Insulinlab Praeparat paa basis af faktor viii til behandling af haemofili a inhibitorpatienter samt fremgangsmaade til fremstilling af et saadan praeparat
US4847362A (en) * 1985-02-01 1989-07-11 New York University Method for purifying antihemophilic factor
US4675385A (en) * 1985-03-27 1987-06-23 Alpha Therapeutic Corporation Isolation of human plasma procoagulant protein factor VIII from biological factors
US4758657A (en) * 1985-07-11 1988-07-19 Armour Pharmaceutical Company Method of purifying Factor VIII:C
AT391808B (de) * 1986-11-03 1990-12-10 Immuno Ag Verfahren zur herstellung einer faktor viii (ahf)-haeltigen fraktion
DE3851696T2 (de) * 1987-12-21 1995-02-23 Miles Inc Faktor VIII- Gelfiltration.
WO1989009784A1 (en) * 1988-04-08 1989-10-19 Commonwealth Serum Laboratories Commission Production of heat-stable factor viii concentrate
ES2042138T3 (es) * 1989-05-24 1993-12-01 Miles Inc. Filtracion en gel del factor viii tratado termicamente.

Also Published As

Publication number Publication date
AU6747090A (en) 1991-06-13
YU210590A (sh) 1993-05-28
UA29421C2 (uk) 2000-11-15
JP2509407B2 (ja) 1996-06-19
FI103510B1 (fi) 1999-07-15
CA2073012A1 (en) 1991-05-10
JPH05501557A (ja) 1993-03-25
CZ537190A3 (cs) 1998-05-13
PL287703A1 (en) 1991-12-02
AU631471B2 (en) 1992-11-26
SK537190A3 (en) 1997-12-10
BG61231B1 (en) 1997-03-31
HU9201551D0 (en) 1992-08-28
CN1044121C (zh) 1999-07-14
DK162233C (da) 1992-03-16
PT95830B (pt) 1997-11-28
ZA908599B (en) 1991-07-31
YU47524B (sh) 1995-10-03
HUT60511A (en) 1992-09-28
SK278640B6 (en) 1997-12-10
RU2055593C1 (ru) 1996-03-10
IE66836B1 (en) 1996-02-07
DK162233B (da) 1991-09-30
FI103510B (fi) 1999-07-15
IL96277A0 (en) 1991-08-16
EP0524172B1 (en) 1995-02-15
US5245014A (en) 1993-09-14
HU214905B (hu) 1998-07-28
DK562189A (da) 1991-05-10
FI922105A0 (fi) 1992-05-08
NO921839L (no) 1992-07-08
NO180741B (no) 1997-03-03
WO1991007438A1 (en) 1991-05-30
PT95830A (pt) 1991-09-30
IE904022A1 (en) 1991-05-22
DE69017050T2 (de) 1995-06-14
DE69017050D1 (de) 1995-03-23
BG96316A (bg) 1993-12-24
NZ236004A (en) 1991-11-26
IL96277A (en) 1995-07-31
ES2068404T3 (es) 1995-04-16
NO921839D0 (no) 1992-05-08
CA2073012C (en) 1996-03-19
EP0524172A1 (en) 1993-01-27
ATE118508T1 (de) 1995-03-15
FI922105A (fi) 1992-05-08
DK562189D0 (da) 1989-11-09
PL164894B1 (pl) 1994-10-31
CN1051732A (zh) 1991-05-29

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Legal Events

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Free format text: LAPSED IN MAY 2003