DK1532145T3 - Pyrazolpræparater der er anvendelige som inhibitorer af GSK-3 - Google Patents

Pyrazolpræparater der er anvendelige som inhibitorer af GSK-3

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Publication number
DK1532145T3
DK1532145T3 DK03767010T DK03767010T DK1532145T3 DK 1532145 T3 DK1532145 T3 DK 1532145T3 DK 03767010 T DK03767010 T DK 03767010T DK 03767010 T DK03767010 T DK 03767010T DK 1532145 T3 DK1532145 T3 DK 1532145T3
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Prior art keywords
gsk
pyrazole
inhibitors
preparations useful
preparations
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Application number
DK03767010T
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Danish (da)
English (en)
Inventor
Larry C Park
Yung-Mae Yao
Cornelia J Forster
Marion W Wannamaker
Original Assignee
Vertex Pharma
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Publication date
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Publication of DK1532145T3 publication Critical patent/DK1532145T3/da

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
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    • A61P25/08—Antiepileptics; Anticonvulsants
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    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
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    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

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  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Neurology (AREA)
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  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
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DK03767010T 2002-08-02 2003-07-31 Pyrazolpræparater der er anvendelige som inhibitorer af GSK-3 DK1532145T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US40096702P 2002-08-02 2002-08-02

Publications (1)

Publication Number Publication Date
DK1532145T3 true DK1532145T3 (da) 2007-01-15

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DK03767010T DK1532145T3 (da) 2002-08-02 2003-07-31 Pyrazolpræparater der er anvendelige som inhibitorer af GSK-3

Country Status (25)

Country Link
US (2) US7491730B2 (enExample)
EP (1) EP1532145B1 (enExample)
JP (3) JP4733388B2 (enExample)
KR (1) KR20050032105A (enExample)
CN (2) CN1319968C (enExample)
AR (1) AR040773A1 (enExample)
AT (1) ATE339419T1 (enExample)
AU (2) AU2003257078B2 (enExample)
BR (1) BR0313176A (enExample)
CA (1) CA2494100C (enExample)
CO (1) CO5700772A2 (enExample)
DE (1) DE60308387T2 (enExample)
DK (1) DK1532145T3 (enExample)
EA (1) EA200500299A1 (enExample)
EC (1) ECSP055640A (enExample)
ES (1) ES2273043T3 (enExample)
IL (1) IL166620A (enExample)
MX (1) MXPA05001367A (enExample)
NO (1) NO20051100L (enExample)
NZ (2) NZ538426A (enExample)
PL (1) PL374967A1 (enExample)
PT (1) PT1532145E (enExample)
TW (1) TWI324157B (enExample)
WO (1) WO2004013140A1 (enExample)
ZA (1) ZA200501124B (enExample)

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