DK1456662T3 - Detektion af autoantistoffer fra patienter, som lider af arthritis rheumatoides - Google Patents
Detektion af autoantistoffer fra patienter, som lider af arthritis rheumatoidesInfo
- Publication number
- DK1456662T3 DK1456662T3 DK02786237T DK02786237T DK1456662T3 DK 1456662 T3 DK1456662 T3 DK 1456662T3 DK 02786237 T DK02786237 T DK 02786237T DK 02786237 T DK02786237 T DK 02786237T DK 1456662 T3 DK1456662 T3 DK 1456662T3
- Authority
- DK
- Denmark
- Prior art keywords
- rheumatoid arthritis
- patients suffering
- autoantibodies
- detection
- peptide
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/52—Cyclic peptides containing at least one abnormal peptide link with only normal peptide links in the ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B30/00—Methods of screening libraries
- C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6878—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids in eptitope analysis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2410/00—Assays, e.g. immunoassays or enzyme assays, involving peptides of less than 20 animo acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/10—Musculoskeletal or connective tissue disorders
- G01N2800/101—Diffuse connective tissue disease, e.g. Sjögren, Wegener's granulomatosis
- G01N2800/102—Arthritis; Rheumatoid arthritis, i.e. inflammation of peripheral joints
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/973—Simultaneous determination of more than one analyte
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/806—Antigenic peptides or proteins
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Rheumatology (AREA)
- Rehabilitation Therapy (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Amplifiers (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL1019540A NL1019540C2 (nl) | 2001-12-11 | 2001-12-11 | Werkwijze voor het detecteren van auto-antilichamen van patienten die lijden aan reumatoïde artritis, peptide en assaykit. |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1456662T3 true DK1456662T3 (da) | 2006-09-18 |
Family
ID=19774384
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK02786237T DK1456662T3 (da) | 2001-12-11 | 2002-12-11 | Detektion af autoantistoffer fra patienter, som lider af arthritis rheumatoides |
Country Status (17)
Country | Link |
---|---|
US (6) | US7888133B2 (fr) |
EP (3) | EP2071335A3 (fr) |
JP (1) | JP4098718B2 (fr) |
CN (4) | CN103524603B (fr) |
AT (1) | ATE329267T1 (fr) |
AU (3) | AU2002354397B2 (fr) |
BR (1) | BRPI0214872B8 (fr) |
CA (5) | CA3076702C (fr) |
CY (1) | CY1105537T1 (fr) |
DE (1) | DE60212186T2 (fr) |
DK (1) | DK1456662T3 (fr) |
ES (1) | ES2266603T3 (fr) |
HK (4) | HK1072805A1 (fr) |
NL (1) | NL1019540C2 (fr) |
PT (1) | PT1456662E (fr) |
SI (1) | SI1456662T1 (fr) |
WO (1) | WO2003050542A2 (fr) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL1019540C2 (nl) * | 2001-12-11 | 2003-07-01 | Stichting Tech Wetenschapp | Werkwijze voor het detecteren van auto-antilichamen van patienten die lijden aan reumatoïde artritis, peptide en assaykit. |
DE602004025636D1 (de) * | 2003-12-23 | 2010-04-01 | Roche Diagnostics Gmbh | Methode zur Beurteilung von rheumatoider Arthritis durch Bestimmung von Anti-CCP und Interleukin 6 |
ATE409314T1 (de) | 2004-02-27 | 2008-10-15 | Hoffmann La Roche | Verfahren zur beurteilung rheumatoider arthritis durch messen von anti-ccp und serumamyloid a |
FR2879604B1 (fr) * | 2004-12-22 | 2010-08-13 | Biomerieux Sa | Peptides citrullines derives de la fibrine reconnus par des auto-anticorps specifiques de la polyarthrite rhumatoide, et leurs utilisations |
ES2310853T3 (es) | 2004-11-04 | 2009-01-16 | Biomerieux | Peptidos citrulinados derivados de la fibrina reconocidos por autoanticuerpos especificos de la poliartritis reumatoide y usos de los mismos. |
EP1877795A4 (fr) * | 2005-05-02 | 2010-04-28 | Brigham & Womens Hospital | Profilage diagnostique d'anticorps seriques |
FI20050814A0 (fi) * | 2005-08-11 | 2005-08-11 | Procollagen Oy | Menetelmä nivelreumassa muodostuvien kollageeniautovasta-aineiden havaitsemiseksi |
JP2010506147A (ja) | 2006-09-29 | 2010-02-25 | エフ.ホフマン−ラ ロシュ アーゲー | 関節リウマチを有する患者のための疾患進行のリスク評価 |
US20100047256A1 (en) | 2007-01-25 | 2010-02-25 | Imperial Innovations Limited | Methods |
ES2307421B1 (es) * | 2007-04-30 | 2009-09-28 | Consejo Superiorde Investigaciones Cientificas (Csic) | Polipeptido quimerico fibrina-filagrina citruinado capaz de detectar los anticuerpos generados en la artritis reumatoide. |
EP2058663A1 (fr) | 2007-11-12 | 2009-05-13 | Euro-Diagnostica B.V. | Procédé pour l'immobilisation d'un analyte sur un support solide |
CA2707870C (fr) * | 2007-12-03 | 2015-01-27 | Sqi Diagnostics Systems Inc. | Peptides synthetiques immunoreactifs avec des auto-anticorps de la polyarthrite rhumatoide |
US20090286256A1 (en) * | 2008-05-19 | 2009-11-19 | Abbott Laboratories | Isolated human autoantibodies to natriuretic peptides and methods and kits for detecting human autoantibodies to natriuretic peptides |
WO2010075249A2 (fr) | 2008-12-22 | 2010-07-01 | Genentech, Inc. | Méthode de traitement de la polyarthrite rhumatoïde avec des antagonistes de cellules b |
FR2940292B1 (fr) * | 2008-12-23 | 2013-05-10 | Isp Investments Inc | Peptides derives d'hmg-coa reductase et composition cosmetique et/ou pharmaceutique les contenant |
EP2204655A1 (fr) | 2008-12-23 | 2010-07-07 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Prédiction de diagnostic de l'arthrite rhumatoïde et lupus érythémateux systémique |
CN102004154B (zh) * | 2009-08-28 | 2013-06-19 | 上海荣盛生物药业有限公司 | 斑点金免疫渗滤法检测类风湿关节炎免疫抗体的组合物 |
CN102012431B (zh) * | 2009-09-04 | 2013-06-19 | 上海荣盛生物药业有限公司 | 斑点金免疫渗滤法检测类风湿关节炎免疫抗体的ccp肽 |
EP2325195A1 (fr) | 2009-11-23 | 2011-05-25 | Toscana Biomarkers S.r.l. | Peptides à citrulline et utilisations associées |
EP2336769A1 (fr) | 2009-12-18 | 2011-06-22 | F. Hoffmann-La Roche AG | Test pour différencier les troubles rhumatismaux des troubles non rhumatismaux |
EP2402368A1 (fr) | 2010-07-02 | 2012-01-04 | Toscana Biomarkers S.r.l. | Peptides de citrulline histone et utilisations associées |
JP6154748B2 (ja) | 2011-02-02 | 2017-06-28 | アカデミス ズィーケンハイス レイデン ハー.オー.デー.エン. エルユーエムセー | 抗カルバミル化タンパク質抗体及び関節炎リスク |
WO2012138294A1 (fr) | 2011-04-05 | 2012-10-11 | Curara Ab | Nouveaux peptides qui se lient à des types de cmh (complexe majeur d'histocompatibilité) de classe ii et leur utilisation en vue de diagnostic et de traitement |
EP2527841A1 (fr) | 2011-05-25 | 2012-11-28 | Toscana Biomarkers S.r.l. | Procédés pour le diagnostic de l'arthrite rhumatoïde |
US9459260B2 (en) * | 2011-05-27 | 2016-10-04 | Nordic Bioscience A/S | Detection of diagnostic peptides |
CN102590530B (zh) * | 2012-03-02 | 2014-06-25 | 常晓天 | Krt84自我免疫抗体作为诊断、检测类风湿性关节炎的诊断标记物的应用 |
SG11201507287SA (en) | 2013-03-15 | 2015-10-29 | Univ California | Peptides having reduced toxicity that stimulate cholesterol efflux |
EP3024849A2 (fr) | 2013-07-24 | 2016-06-01 | Vilara AB | Nouveaux anticorps pour le diagnostic et le traitement de la polyarthrite rhumatoïde |
EP3140323B8 (fr) * | 2014-05-05 | 2018-05-23 | Novio TH B.V. | Procédé de diagnostic sérologique de la polyarthrite rhumatoïde |
CN104262489B (zh) * | 2014-09-30 | 2017-01-11 | 陈仁奋 | 一种环状瓜氨酸嵌合肽抗原及其应用 |
EP3056903A1 (fr) | 2015-02-13 | 2016-08-17 | F. Hoffmann-La Roche AG | Procédé d'évaluation de l'arthrite rhumatoïde par la mesure de l'anti-CCP et de l'anti-Casp8 |
EP3056904A1 (fr) | 2015-02-13 | 2016-08-17 | F. Hoffmann-La Roche AG | Procédé pour l'évaluation de l'arthrite rhumatoïde par la mesure de l'anti-CCP et de l'anti-MCM3 |
CN107484423A (zh) | 2015-02-13 | 2017-12-15 | 豪夫迈·罗氏有限公司 | 通过测量抗ccp和抗pik3cd来评估类风湿性关节炎的方法 |
WO2017072494A1 (fr) * | 2015-10-30 | 2017-05-04 | Oxford University Innovation Ltd. | Peptide et biomarqueur associés à des troubles inflammatoires, et leurs utilisations |
EP3523657B1 (fr) | 2016-10-04 | 2023-06-21 | F. Hoffmann-La Roche AG | Système et procédé d'identification d'un classificateur synthétique |
CN106543277B (zh) * | 2016-10-31 | 2020-02-14 | 中南大学 | 一种与移植排斥相关的内皮细胞抗原及其应用、试剂盒 |
CN108196073B (zh) * | 2018-03-13 | 2019-09-13 | 江苏浩欧博生物医药股份有限公司 | 一种测定抗环瓜氨酸肽抗体的试剂盒及其应用 |
CN108948173B (zh) * | 2018-05-22 | 2020-11-03 | 北京蛋白质组研究中心 | 一种瓜氨酸修饰肽及其应用 |
CN108948153B (zh) * | 2018-05-22 | 2020-11-03 | 北京蛋白质组研究中心 | 一种瓜氨酸修饰肽抗原组合及其应用 |
TWI744777B (zh) * | 2019-01-27 | 2021-11-01 | 中國醫藥大學 | 一種類風溼關節炎自體抗體結合的胜肽及其應用 |
CN109929009B (zh) * | 2019-03-20 | 2021-06-04 | 深圳市新产业生物医学工程股份有限公司 | Ccp肽段、包含其的抗原、试剂、试剂盒及应用 |
CN114805598A (zh) * | 2019-04-28 | 2022-07-29 | 广州市雷德生物科技有限公司 | 促进蛋白二聚体形成的拉链扣结构及其应用 |
WO2020221153A1 (fr) * | 2019-04-28 | 2020-11-05 | 广州市雷德生物科技有限公司 | Structure de fermeture à glissière permettant de favoriser la formation d'un dimère protéique et son utilisation |
CN114573663B (zh) * | 2019-08-27 | 2023-08-11 | 广东菲鹏生物有限公司 | 瓜氨酸肽及其应用、类风湿关节炎的检测试剂与试剂盒 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992019649A1 (fr) * | 1991-04-26 | 1992-11-12 | Clonatec | Antigenes reconnus par des anticorps de la polyarthrite rhumatoide, leur preparation et leurs applications |
US5610297A (en) * | 1991-12-27 | 1997-03-11 | Georgia Tech Research Corp. | Peptides ketoamides |
US5314804A (en) * | 1992-03-24 | 1994-05-24 | Serim Research Corporation | Test for Helicobacter pylori |
CN1153530A (zh) * | 1995-03-09 | 1997-07-02 | 比奥美希奥公司 | 相关于类风湿性关节炎的msrv-1病毒和致病性和/或感染性msrv-2因子 |
KR0182853B1 (ko) * | 1995-08-07 | 1999-05-15 | 김신규 | 자가면역 질환의 진단 방법 |
FR2752842B1 (fr) * | 1996-08-30 | 1998-11-06 | Biomerieux Sa | Antigenes derives des filaggrines et leur utilisation pour le diagnostic de la polyarthrite rhumatoide |
NL1004539C2 (nl) * | 1996-11-15 | 1998-05-20 | Stichting Tech Wetenschapp | Peptide afgeleid van een door auto-antilichamen van patiënten met reumatoïde artritis herkend antigeen, antilichaam daartegen en werkwijze voor het detecteren van auto-immuunantilichamen. |
HUP0004338A2 (hu) * | 1997-11-28 | 2001-02-28 | Innogenetics N.V. | Raumatoid artritiszben szenvedő betegek széruma által felismert, citrullint tartalmazó szintetikus peptidek diagnosztikai és terápiás alkalmazásai |
FR2773157B1 (fr) * | 1997-12-30 | 2001-10-05 | Bio Merieux | Epitopes peptidiques reconnus par des auto-anticorps antifilaggrine presents dans le serum des patients atteints de polyarthrite rhumatoide |
GB9805477D0 (en) * | 1998-03-13 | 1998-05-13 | Oxford Glycosciences Limited | Methods and compositions for diagnosis of rheumatoid arthritis |
GB9822115D0 (en) * | 1998-10-09 | 1998-12-02 | King S College London | Treatment of inflammatory disease |
FR2795735B1 (fr) | 1999-07-01 | 2001-09-07 | Univ Toulouse | Derives citrullines de la fibrine et leur utilisation pour le diagnostic ou le traitement de la polyarthrite rhumatoide |
ES2174770T1 (es) * | 1999-12-21 | 2002-11-16 | Innogenetics Nv | Peptidos diseñados para el diagnostico y el tratamiento de artritis reumatoide. |
AUPQ776100A0 (en) * | 2000-05-26 | 2000-06-15 | Australian National University, The | Synthetic molecules and uses therefor |
NL1019540C2 (nl) * | 2001-12-11 | 2003-07-01 | Stichting Tech Wetenschapp | Werkwijze voor het detecteren van auto-antilichamen van patienten die lijden aan reumatoïde artritis, peptide en assaykit. |
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2001
- 2001-12-11 NL NL1019540A patent/NL1019540C2/nl not_active IP Right Cessation
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2002
- 2002-12-11 WO PCT/NL2002/000815 patent/WO2003050542A2/fr active IP Right Grant
- 2002-12-11 CA CA3076702A patent/CA3076702C/fr not_active Expired - Lifetime
- 2002-12-11 CN CN201310482892.9A patent/CN103524603B/zh not_active Expired - Lifetime
- 2002-12-11 BR BRPI0214872A patent/BRPI0214872B8/pt not_active IP Right Cessation
- 2002-12-11 AU AU2002354397A patent/AU2002354397B2/en not_active Expired
- 2002-12-11 DE DE60212186T patent/DE60212186T2/de not_active Expired - Lifetime
- 2002-12-11 CA CA2708463A patent/CA2708463C/fr not_active Expired - Lifetime
- 2002-12-11 EP EP09155765A patent/EP2071335A3/fr not_active Withdrawn
- 2002-12-11 CN CN200810215984XA patent/CN101408546B/zh not_active Expired - Lifetime
- 2002-12-11 CA CA2969577A patent/CA2969577C/fr not_active Expired - Lifetime
- 2002-12-11 EP EP06114882A patent/EP1693673A3/fr not_active Ceased
- 2002-12-11 CN CNB028246470A patent/CN100424509C/zh not_active Expired - Lifetime
- 2002-12-11 JP JP2003551544A patent/JP4098718B2/ja not_active Expired - Lifetime
- 2002-12-11 CN CN201610039155.5A patent/CN105699648B/zh not_active Expired - Lifetime
- 2002-12-11 DK DK02786237T patent/DK1456662T3/da active
- 2002-12-11 CA CA2892001A patent/CA2892001C/fr not_active Expired - Lifetime
- 2002-12-11 AT AT02786237T patent/ATE329267T1/de active
- 2002-12-11 PT PT02786237T patent/PT1456662E/pt unknown
- 2002-12-11 ES ES02786237T patent/ES2266603T3/es not_active Expired - Lifetime
- 2002-12-11 US US10/497,667 patent/US7888133B2/en active Active
- 2002-12-11 EP EP02786237A patent/EP1456662B1/fr not_active Expired - Lifetime
- 2002-12-11 CA CA2489167A patent/CA2489167C/fr not_active Expired - Lifetime
- 2002-12-11 SI SI200230389T patent/SI1456662T1/sl unknown
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2005
- 2005-03-15 HK HK05102287A patent/HK1072805A1/xx not_active IP Right Cessation
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2006
- 2006-09-07 CY CY20061101278T patent/CY1105537T1/el unknown
- 2006-10-18 AU AU2006230702A patent/AU2006230702A1/en not_active Abandoned
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2009
- 2009-07-03 HK HK09105983.9A patent/HK1128329A1/xx not_active IP Right Cessation
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2010
- 2010-02-22 AU AU2010200648A patent/AU2010200648B2/en not_active Expired
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2011
- 2011-01-24 US US13/012,739 patent/US8481332B2/en not_active Expired - Lifetime
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2013
- 2013-06-17 US US13/920,017 patent/US8759114B2/en not_active Expired - Lifetime
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2014
- 2014-05-23 US US14/286,878 patent/US9689871B2/en not_active Expired - Lifetime
- 2014-06-06 HK HK14105323.1A patent/HK1191962A1/zh not_active IP Right Cessation
-
2016
- 2016-12-22 HK HK16114605A patent/HK1226143B/zh not_active IP Right Cessation
-
2017
- 2017-05-31 US US15/610,398 patent/US10119966B2/en not_active Expired - Lifetime
-
2018
- 2018-11-02 US US16/178,848 patent/US20190056393A1/en not_active Abandoned
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