DK1456662T3 - Detektion af autoantistoffer fra patienter, som lider af arthritis rheumatoides - Google Patents

Detektion af autoantistoffer fra patienter, som lider af arthritis rheumatoides

Info

Publication number
DK1456662T3
DK1456662T3 DK02786237T DK02786237T DK1456662T3 DK 1456662 T3 DK1456662 T3 DK 1456662T3 DK 02786237 T DK02786237 T DK 02786237T DK 02786237 T DK02786237 T DK 02786237T DK 1456662 T3 DK1456662 T3 DK 1456662T3
Authority
DK
Denmark
Prior art keywords
rheumatoid arthritis
patients suffering
autoantibodies
detection
peptide
Prior art date
Application number
DK02786237T
Other languages
English (en)
Inventor
Venrooij Waltherus Jacobus Van
Jan Wouter Drijfhout
Boekel Martinus Adrianus M Van
Gerardus Jozef Maria Pruijn
Original Assignee
Stichting Tech Wetenschapp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stichting Tech Wetenschapp filed Critical Stichting Tech Wetenschapp
Application granted granted Critical
Publication of DK1456662T3 publication Critical patent/DK1456662T3/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/52—Cyclic peptides containing at least one abnormal peptide link with only normal peptide links in the ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6878—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids in eptitope analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2410/00—Assays, e.g. immunoassays or enzyme assays, involving peptides of less than 20 animo acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/10—Musculoskeletal or connective tissue disorders
    • G01N2800/101—Diffuse connective tissue disease, e.g. Sjögren, Wegener's granulomatosis
    • G01N2800/102—Arthritis; Rheumatoid arthritis, i.e. inflammation of peripheral joints
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/973—Simultaneous determination of more than one analyte
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/806—Antigenic peptides or proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Rehabilitation Therapy (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Amplifiers (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK02786237T 2001-12-11 2002-12-11 Detektion af autoantistoffer fra patienter, som lider af arthritis rheumatoides DK1456662T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL1019540A NL1019540C2 (nl) 2001-12-11 2001-12-11 Werkwijze voor het detecteren van auto-antilichamen van patienten die lijden aan reumatoïde artritis, peptide en assaykit.

Publications (1)

Publication Number Publication Date
DK1456662T3 true DK1456662T3 (da) 2006-09-18

Family

ID=19774384

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02786237T DK1456662T3 (da) 2001-12-11 2002-12-11 Detektion af autoantistoffer fra patienter, som lider af arthritis rheumatoides

Country Status (17)

Country Link
US (6) US7888133B2 (da)
EP (3) EP1456662B1 (da)
JP (1) JP4098718B2 (da)
CN (4) CN101408546B (da)
AT (1) ATE329267T1 (da)
AU (3) AU2002354397B2 (da)
BR (1) BRPI0214872B8 (da)
CA (5) CA2489167C (da)
CY (1) CY1105537T1 (da)
DE (1) DE60212186T2 (da)
DK (1) DK1456662T3 (da)
ES (1) ES2266603T3 (da)
HK (4) HK1072805A1 (da)
NL (1) NL1019540C2 (da)
PT (1) PT1456662E (da)
SI (1) SI1456662T1 (da)
WO (1) WO2003050542A2 (da)

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NL1019540C2 (nl) 2001-12-11 2003-07-01 Stichting Tech Wetenschapp Werkwijze voor het detecteren van auto-antilichamen van patienten die lijden aan reumatoïde artritis, peptide en assaykit.
EP1882946B1 (en) 2003-12-23 2010-02-17 Roche Diagnostics GmbH Method of assessing rheumatoid arthritis by measuring anti-CCP and interleukin 6
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CN106543277B (zh) * 2016-10-31 2020-02-14 中南大学 一种与移植排斥相关的内皮细胞抗原及其应用、试剂盒
CN108196073B (zh) * 2018-03-13 2019-09-13 江苏浩欧博生物医药股份有限公司 一种测定抗环瓜氨酸肽抗体的试剂盒及其应用
CN108948173B (zh) * 2018-05-22 2020-11-03 北京蛋白质组研究中心 一种瓜氨酸修饰肽及其应用
CN108948153B (zh) * 2018-05-22 2020-11-03 北京蛋白质组研究中心 一种瓜氨酸修饰肽抗原组合及其应用
CN112638935A (zh) * 2019-01-27 2021-04-09 中国医药大学 一种类风湿性关节炎自体抗体结合的肽及其应用
CN109929009B (zh) * 2019-03-20 2021-06-04 深圳市新产业生物医学工程股份有限公司 Ccp肽段、包含其的抗原、试剂、试剂盒及应用
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Also Published As

Publication number Publication date
CN103524603B (zh) 2016-02-24
CA2969577A1 (en) 2003-06-19
US9689871B2 (en) 2017-06-27
BR0214872A (pt) 2004-10-26
CN1602426A (zh) 2005-03-30
CN105699648B (zh) 2017-10-20
DE60212186T2 (de) 2007-04-12
NL1019540C2 (nl) 2003-07-01
ES2266603T3 (es) 2007-03-01
AU2002354397A1 (en) 2003-06-23
US20070087380A1 (en) 2007-04-19
BRPI0214872B8 (pt) 2021-07-27
ATE329267T1 (de) 2006-06-15
AU2006230702A1 (en) 2006-11-09
EP1693673A3 (en) 2006-12-06
EP2071335A3 (en) 2009-09-02
AU2002354397B2 (en) 2006-07-20
US20170269078A1 (en) 2017-09-21
AU2010200648A1 (en) 2010-03-11
DE60212186D1 (de) 2006-07-20
JP2005512092A (ja) 2005-04-28
CA2489167A1 (en) 2003-06-19
US7888133B2 (en) 2011-02-15
EP1456662B1 (en) 2006-06-07
CA3076702A1 (en) 2003-06-19
WO2003050542A3 (en) 2003-12-11
US20140336069A1 (en) 2014-11-13
HK1191962A1 (zh) 2014-08-08
HK1072805A1 (en) 2005-09-09
EP2071335A2 (en) 2009-06-17
US10119966B2 (en) 2018-11-06
US8481332B2 (en) 2013-07-09
CN103524603A (zh) 2014-01-22
CA2892001C (en) 2017-07-18
US8759114B2 (en) 2014-06-24
AU2010200648B2 (en) 2012-07-12
US20190056393A1 (en) 2019-02-21
CY1105537T1 (el) 2010-07-28
BRPI0214872B1 (pt) 2016-12-13
PT1456662E (pt) 2006-10-31
US20130267677A1 (en) 2013-10-10
US20110195861A1 (en) 2011-08-11
JP4098718B2 (ja) 2008-06-11
SI1456662T1 (sl) 2006-12-31
HK1128329A1 (en) 2009-10-23
HK1226143B (zh) 2017-09-22
CN100424509C (zh) 2008-10-08
EP1456662A2 (en) 2004-09-15
EP1693673A2 (en) 2006-08-23
CA2489167C (en) 2010-08-10
CA2969577C (en) 2020-04-14
CA2708463A1 (en) 2003-06-19
CN101408546B (zh) 2013-10-30
CN101408546A (zh) 2009-04-15
CA2892001A1 (en) 2003-06-19
CA2708463C (en) 2015-08-11
WO2003050542A2 (en) 2003-06-19
CA3076702C (en) 2022-03-29
CN105699648A (zh) 2016-06-22

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