DK1373255T3 - Fremgangsmåde til fremstilling af imidazolforbindelser - Google Patents

Fremgangsmåde til fremstilling af imidazolforbindelser

Info

Publication number
DK1373255T3
DK1373255T3 DK02722184T DK02722184T DK1373255T3 DK 1373255 T3 DK1373255 T3 DK 1373255T3 DK 02722184 T DK02722184 T DK 02722184T DK 02722184 T DK02722184 T DK 02722184T DK 1373255 T3 DK1373255 T3 DK 1373255T3
Authority
DK
Denmark
Prior art keywords
preparation
imidazole compounds
imidazole
compounds
Prior art date
Application number
DK02722184T
Other languages
Danish (da)
English (en)
Inventor
Walter F M Filliers
Rudy L M Broeckx
Stefan M H Leurs
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of DK1373255T3 publication Critical patent/DK1373255T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Epoxy Resins (AREA)
DK02722184T 2001-03-12 2002-03-05 Fremgangsmåde til fremstilling af imidazolforbindelser DK1373255T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01200928 2001-03-12
PCT/EP2002/002459 WO2002072574A1 (en) 2001-03-12 2002-03-05 Process for the preparation of imidazole compounds

Publications (1)

Publication Number Publication Date
DK1373255T3 true DK1373255T3 (da) 2005-05-23

Family

ID=8180004

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02722184T DK1373255T3 (da) 2001-03-12 2002-03-05 Fremgangsmåde til fremstilling af imidazolforbindelser

Country Status (31)

Country Link
US (1) US6844439B2 (cs)
EP (1) EP1373255B1 (cs)
JP (1) JP4257698B2 (cs)
KR (1) KR100849042B1 (cs)
CN (1) CN1246318C (cs)
AR (1) AR035944A1 (cs)
AT (1) ATE287882T1 (cs)
AU (1) AU2002253101B2 (cs)
BR (1) BRPI0208075B8 (cs)
CA (1) CA2438421C (cs)
CZ (1) CZ300622B6 (cs)
DE (1) DE60202755T2 (cs)
DK (1) DK1373255T3 (cs)
EA (1) EA006770B1 (cs)
EE (1) EE05247B1 (cs)
ES (1) ES2236505T3 (cs)
HR (1) HRP20030695B1 (cs)
HU (1) HU230282B1 (cs)
IL (2) IL157839A0 (cs)
MX (1) MXPA03008205A (cs)
MY (1) MY124838A (cs)
NO (1) NO324954B1 (cs)
NZ (1) NZ528620A (cs)
PL (1) PL208238B1 (cs)
PT (1) PT1373255E (cs)
SI (1) SI1373255T1 (cs)
SK (1) SK287807B6 (cs)
TW (1) TWI249532B (cs)
UA (1) UA74871C2 (cs)
WO (1) WO2002072574A1 (cs)
ZA (1) ZA200307117B (cs)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002072090A1 (en) 2001-03-12 2002-09-19 Avanir Pharmaceuticals Benzimidazole compounds for modulating ige and inhibiting cellular proliferation
TWI276631B (en) 2002-09-12 2007-03-21 Avanir Pharmaceuticals Phenyl-aza-benzimidazole compounds for modulating IgE and inhibiting cellular proliferation
AU2003270426A1 (en) 2002-09-12 2004-04-30 Avanir Pharmaceuticals PHENYL-INDOLE COMPOUNDS FOR MODULATING IgE AND INHIBITING CELLULAR PROLIFERATION
US20060106060A1 (en) * 2004-03-18 2006-05-18 The Brigham And Women's Hospital, Inc. Methods for the treatment of synucleinopathies (Lansbury)
ATE471316T1 (de) 2004-05-03 2010-07-15 Janssen Pharmaceutica Nv Diastereoselektives syntheseverfahren mit 6-brom- 4-(3-chlorphenyl)-2-methoxychinolin
ES2308486T3 (es) 2004-05-03 2008-12-01 Janssen Pharmaceutica Nv Proceso de sintesis diastereoselectiva para la preparacion de compuestos de imidazol.
US7524961B2 (en) 2004-05-03 2009-04-28 Janssen Pharmaceutica, N.V. Diastereoselective addition of lithiated N-methylimidazole on sulfinimines
US20070213366A1 (en) 2005-12-23 2007-09-13 Justman Craig J Treatment of Synucleinopathies
WO2009151683A2 (en) * 2008-03-12 2009-12-17 Link Medicine Corporation Quinolinone farnesyl transferase inhibitors for the treatment of synucleinopathies and other indications
KR101044430B1 (ko) * 2009-09-25 2011-06-27 듀오백코리아 주식회사 요추받이를 포함하는 의자의 등 지지 장치
KR101107900B1 (ko) * 2009-10-21 2012-01-25 성용기업 주식회사 의자용 허리지지장치
EP3385395B9 (en) 2015-08-17 2020-05-20 Kura Oncology, Inc. Methods of treating cancer patients with farnesyl transferase inhibitors
US11124839B2 (en) 2016-11-03 2021-09-21 Kura Oncology, Inc. Methods of treating cancer patients with farnesyltransferase inhibitors
WO2018103027A1 (zh) 2016-12-08 2018-06-14 杭州领业医药科技有限公司 替吡法尼的晶型及其制备方法及药物组合物
EP3793966A1 (en) 2018-05-18 2021-03-24 Kura Oncology, Inc. Synthesis of tipifarnib

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW349948B (en) 1995-10-31 1999-01-11 Janssen Pharmaceutica Nv Farnesyl transferase inhibiting 2-quinolone derivatives
EP0865440B1 (en) 1995-12-08 2002-04-03 Janssen Pharmaceutica N.V. Farnesyl protein transferase inhibiting (imidazol-5-yl)methyl-2-quinolinone derivatives
TW591030B (en) * 1997-03-10 2004-06-11 Janssen Pharmaceutica Nv Farnesyl transferase inhibiting 1,8-annelated quinolinone derivatives substituted with N- or C-linked imidazoles
US6177432B1 (en) 1997-04-25 2001-01-23 Janssen-Cilag S.A. Farnesyltransferase inhibiting quinazolinones
DE69923849T2 (de) 1998-08-27 2006-01-12 Pfizer Products Inc., Groton Quinolin-2-on-derivate verwendbar als antikrebsmittel
TR200101343T2 (tr) * 1998-08-27 2001-09-21 Pfizer Products Inc. Kansere karşı kullanılan maddeler olarak alkinil-ikame edilmiş kinolin-2-on türevleri

Also Published As

Publication number Publication date
JP4257698B2 (ja) 2009-04-22
PL363263A1 (en) 2004-11-15
TWI249532B (en) 2006-02-21
IL157839A (en) 2008-07-08
MXPA03008205A (es) 2004-01-29
NO20034003D0 (no) 2003-09-10
EA200300998A1 (ru) 2004-02-26
EE05247B1 (et) 2009-12-15
PL208238B1 (pl) 2011-04-29
US20040138256A1 (en) 2004-07-15
BR0208075A (pt) 2004-03-02
HUP0303443A2 (hu) 2004-01-28
CN1496363A (zh) 2004-05-12
MY124838A (en) 2006-07-31
DE60202755D1 (de) 2005-03-03
US6844439B2 (en) 2005-01-18
CZ20032704A3 (en) 2004-03-17
CA2438421C (en) 2010-05-18
NO20034003L (no) 2003-10-22
IL157839A0 (en) 2004-03-28
ZA200307117B (en) 2004-09-13
NZ528620A (en) 2005-01-28
CZ300622B6 (cs) 2009-07-01
WO2002072574A1 (en) 2002-09-19
EP1373255A1 (en) 2004-01-02
KR100849042B1 (ko) 2008-07-29
HUP0303443A3 (en) 2012-09-28
EP1373255B1 (en) 2005-01-26
HK1063315A1 (zh) 2004-12-24
CN1246318C (zh) 2006-03-22
HRP20030695B1 (hr) 2011-07-31
SI1373255T1 (cs) 2005-08-31
SK287807B6 (sk) 2011-10-04
EA006770B1 (ru) 2006-04-28
HU230282B1 (hu) 2015-12-28
KR20030079971A (ko) 2003-10-10
EE200300442A (et) 2003-12-15
CA2438421A1 (en) 2002-09-19
ES2236505T3 (es) 2005-07-16
DE60202755T2 (de) 2006-03-30
JP2004523575A (ja) 2004-08-05
HRP20030695A2 (en) 2005-02-28
BRPI0208075B8 (pt) 2021-05-25
ATE287882T1 (de) 2005-02-15
NO324954B1 (no) 2008-01-14
AR035944A1 (es) 2004-07-28
BRPI0208075B1 (pt) 2018-02-14
AU2002253101B2 (en) 2007-08-09
PT1373255E (pt) 2005-05-31
SK12462003A3 (sk) 2004-06-08
UA74871C2 (en) 2006-02-15

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