HRP20030695B1 - Postupak za pripravljanje imidazolnih spojeva - Google Patents

Postupak za pripravljanje imidazolnih spojeva

Info

Publication number
HRP20030695B1
HRP20030695B1 HR20030695A HRP20030695A HRP20030695B1 HR P20030695 B1 HRP20030695 B1 HR P20030695B1 HR 20030695 A HR20030695 A HR 20030695A HR P20030695 A HRP20030695 A HR P20030695A HR P20030695 B1 HRP20030695 B1 HR P20030695B1
Authority
HR
Croatia
Prior art keywords
preparation
methyl
procedure
imidazole compounds
chlorophenyl
Prior art date
Application number
HR20030695A
Other languages
English (en)
Croatian (hr)
Inventor
Ferdinand Maria Filliers Walter
Laurent Maria Broeckx Rudy
Marcel Herman Leurs Stefan
Original Assignee
Janssen Pharmaceutica N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.
Publication of HRP20030695A2 publication Critical patent/HRP20030695A2/hr
Publication of HRP20030695B1 publication Critical patent/HRP20030695B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Epoxy Resins (AREA)
HR20030695A 2001-03-12 2002-03-05 Postupak za pripravljanje imidazolnih spojeva HRP20030695B1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01200928 2001-03-12
PCT/EP2002/002459 WO2002072574A1 (en) 2001-03-12 2002-03-05 Process for the preparation of imidazole compounds

Publications (2)

Publication Number Publication Date
HRP20030695A2 HRP20030695A2 (en) 2005-02-28
HRP20030695B1 true HRP20030695B1 (hr) 2011-07-31

Family

ID=8180004

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20030695A HRP20030695B1 (hr) 2001-03-12 2002-03-05 Postupak za pripravljanje imidazolnih spojeva

Country Status (31)

Country Link
US (1) US6844439B2 (cs)
EP (1) EP1373255B1 (cs)
JP (1) JP4257698B2 (cs)
KR (1) KR100849042B1 (cs)
CN (1) CN1246318C (cs)
AR (1) AR035944A1 (cs)
AT (1) ATE287882T1 (cs)
AU (1) AU2002253101B2 (cs)
BR (1) BRPI0208075B8 (cs)
CA (1) CA2438421C (cs)
CZ (1) CZ300622B6 (cs)
DE (1) DE60202755T2 (cs)
DK (1) DK1373255T3 (cs)
EA (1) EA006770B1 (cs)
EE (1) EE05247B1 (cs)
ES (1) ES2236505T3 (cs)
HR (1) HRP20030695B1 (cs)
HU (1) HU230282B1 (cs)
IL (2) IL157839A0 (cs)
MX (1) MXPA03008205A (cs)
MY (1) MY124838A (cs)
NO (1) NO324954B1 (cs)
NZ (1) NZ528620A (cs)
PL (1) PL208238B1 (cs)
PT (1) PT1373255E (cs)
SI (1) SI1373255T1 (cs)
SK (1) SK287807B6 (cs)
TW (1) TWI249532B (cs)
UA (1) UA74871C2 (cs)
WO (1) WO2002072574A1 (cs)
ZA (1) ZA200307117B (cs)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ20032691A3 (en) 2001-03-12 2004-04-14 Avanir Pharmaceuticals Benzimidazole compounds for modulating ige and inhibiting cellular proliferation
TWI276631B (en) 2002-09-12 2007-03-21 Avanir Pharmaceuticals Phenyl-aza-benzimidazole compounds for modulating IgE and inhibiting cellular proliferation
WO2004024655A2 (en) 2002-09-12 2004-03-25 Avanir Pharmaceuticals Phenyl-indole compounds for modulating ige and inhibiting cellular proliferation
WO2005089504A2 (en) * 2004-03-18 2005-09-29 The Brigham And Women's Hospital, Inc. Methods for the treatment of synucleinopathies
WO2005105782A1 (en) 2004-05-03 2005-11-10 Janssen Pharmaceutica N.V. Diastereoselective addition of lithiated n-methylimidazole on sulfinimines
AU2005238223B2 (en) 2004-05-03 2012-04-26 Janssen Pharmaceutica N.V. Diastereoselective synthesis process for the preparation of imidazole compounds
JP4917022B2 (ja) * 2004-05-03 2012-04-18 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ ６−ブロモ−４−（３−クロロフェニル）−２−メトキシ−キノリンを用いるジアステレオ選択的合成方法
JP2009521470A (ja) 2005-12-23 2009-06-04 リンク メディシン コーポレイション シヌクレイン障害の治療
WO2009151683A2 (en) * 2008-03-12 2009-12-17 Link Medicine Corporation Quinolinone farnesyl transferase inhibitors for the treatment of synucleinopathies and other indications
KR101044430B1 (ko) * 2009-09-25 2011-06-27 듀오백코리아 주식회사 요추받이를 포함하는 의자의 등 지지 장치
KR101107900B1 (ko) * 2009-10-21 2012-01-25 성용기업 주식회사 의자용 허리지지장치
PT3640345T (pt) 2015-08-17 2021-12-29 Kura Oncology Inc Métodos de tratamento de doentes com cancro usando inibidores da farnesiltransferase
KR20190082247A (ko) 2016-11-03 2019-07-09 쿠라 온콜로지, 인크. 파르네실전달효소 억제제를 이용하여 암 환자를 치료하는 방법
WO2018103027A1 (zh) 2016-12-08 2018-06-14 杭州领业医药科技有限公司 替吡法尼的晶型及其制备方法及药物组合物
JP2021526513A (ja) * 2018-05-18 2021-10-07 クラ オンコロジー， インコーポレイテッド ティピファニブの合成

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997021701A1 (en) * 1995-12-08 1997-06-19 Janssen Pharmaceutica N.V. Farnesyl protein transferase inhibiting (imidazol-5-yl)methyl-2-quinolinone derivatives
WO2000012499A1 (en) * 1998-08-27 2000-03-09 Pfizer Products Inc. Alkynyl-substituted quinolin-2-one derivatives useful as anticancer agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW349948B (en) 1995-10-31 1999-01-11 Janssen Pharmaceutica Nv Farnesyl transferase inhibiting 2-quinolone derivatives
TW591030B (en) 1997-03-10 2004-06-11 Janssen Pharmaceutica Nv Farnesyl transferase inhibiting 1,8-annelated quinolinone derivatives substituted with N- or C-linked imidazoles
ES2289783T3 (es) * 1997-04-25 2008-02-01 Janssen Pharmaceutica N.V. Quinazolinonas que inhiben la farnesiltransferasa.
DE69923849T2 (de) 1998-08-27 2006-01-12 Pfizer Products Inc., Groton Quinolin-2-on-derivate verwendbar als antikrebsmittel

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997021701A1 (en) * 1995-12-08 1997-06-19 Janssen Pharmaceutica N.V. Farnesyl protein transferase inhibiting (imidazol-5-yl)methyl-2-quinolinone derivatives
WO2000012499A1 (en) * 1998-08-27 2000-03-09 Pfizer Products Inc. Alkynyl-substituted quinolin-2-one derivatives useful as anticancer agents

Also Published As

Publication number Publication date
KR20030079971A (ko) 2003-10-10
CN1246318C (zh) 2006-03-22
EA006770B1 (ru) 2006-04-28
EA200300998A1 (ru) 2004-02-26
SI1373255T1 (cs) 2005-08-31
EP1373255B1 (en) 2005-01-26
NZ528620A (en) 2005-01-28
BR0208075A (pt) 2004-03-02
ATE287882T1 (de) 2005-02-15
IL157839A0 (en) 2004-03-28
ES2236505T3 (es) 2005-07-16
JP4257698B2 (ja) 2009-04-22
EE200300442A (et) 2003-12-15
HUP0303443A2 (hu) 2004-01-28
CA2438421A1 (en) 2002-09-19
IL157839A (en) 2008-07-08
US20040138256A1 (en) 2004-07-15
DE60202755D1 (de) 2005-03-03
HUP0303443A3 (en) 2012-09-28
AR035944A1 (es) 2004-07-28
PT1373255E (pt) 2005-05-31
UA74871C2 (en) 2006-02-15
MXPA03008205A (es) 2004-01-29
AU2002253101B2 (en) 2007-08-09
TWI249532B (en) 2006-02-21
JP2004523575A (ja) 2004-08-05
NO324954B1 (no) 2008-01-14
KR100849042B1 (ko) 2008-07-29
DK1373255T3 (da) 2005-05-23
CN1496363A (zh) 2004-05-12
CZ300622B6 (cs) 2009-07-01
SK12462003A3 (sk) 2004-06-08
DE60202755T2 (de) 2006-03-30
HU230282B1 (hu) 2015-12-28
PL363263A1 (en) 2004-11-15
BRPI0208075B8 (pt) 2021-05-25
WO2002072574A1 (en) 2002-09-19
NO20034003D0 (no) 2003-09-10
EP1373255A1 (en) 2004-01-02
NO20034003L (no) 2003-10-22
HRP20030695A2 (en) 2005-02-28
HK1063315A1 (zh) 2004-12-24
SK287807B6 (sk) 2011-10-04
ZA200307117B (en) 2004-09-13
US6844439B2 (en) 2005-01-18
CA2438421C (en) 2010-05-18
CZ20032704A3 (en) 2004-03-17
PL208238B1 (pl) 2011-04-29
MY124838A (en) 2006-07-31
EE05247B1 (et) 2009-12-15
BRPI0208075B1 (pt) 2018-02-14

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