DK13585D0 - Proteinpraeparat, monoklonalt antistof fremstillet dermed, fremgangsmaade og middel til detektering, dna-sekvens og extrachromosomalt element indeholdende en saadan dna-sekvens - Google Patents

Proteinpraeparat, monoklonalt antistof fremstillet dermed, fremgangsmaade og middel til detektering, dna-sekvens og extrachromosomalt element indeholdende en saadan dna-sekvens

Info

Publication number
DK13585D0
DK13585D0 DK13585A DK13585A DK13585D0 DK 13585 D0 DK13585 D0 DK 13585D0 DK 13585 A DK13585 A DK 13585A DK 13585 A DK13585 A DK 13585A DK 13585 D0 DK13585 D0 DK 13585D0
Authority
DK
Denmark
Prior art keywords
sequence
dna
protein
detection
monoclonal antibody
Prior art date
Application number
DK13585A
Other languages
English (en)
Other versions
DK165506C (da
DK13585A (da
DK165506B (da
Inventor
George Kuo
Frank R Masiarz
Martha Truett
Pablo Valenzuela
Mirella Ezban Rasmussen
Jennifer Favaloro
Original Assignee
Chiron Corp
Nordisk Gentofte
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27075219&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK13585(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US06/570,062 external-priority patent/US5004804A/en
Application filed by Chiron Corp, Nordisk Gentofte filed Critical Chiron Corp
Publication of DK13585D0 publication Critical patent/DK13585D0/da
Publication of DK13585A publication Critical patent/DK13585A/da
Publication of DK165506B publication Critical patent/DK165506B/da
Application granted granted Critical
Publication of DK165506C publication Critical patent/DK165506C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • C07K14/755Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK013585A 1984-01-12 1985-01-11 Proteinpraeparat med koagulationsaktivitet samt fremgangsmaade til fremstilling deraf DK165506C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US57006284 1984-01-12
US06/570,062 US5004804A (en) 1984-01-12 1984-01-12 Method and composition for preparation of factor VIIIC
US66491984A 1984-10-26 1984-10-26
US66491984 1984-10-26

Publications (4)

Publication Number Publication Date
DK13585D0 true DK13585D0 (da) 1985-01-11
DK13585A DK13585A (da) 1985-09-11
DK165506B DK165506B (da) 1992-12-07
DK165506C DK165506C (da) 1993-04-19

Family

ID=27075219

Family Applications (3)

Application Number Title Priority Date Filing Date
DK013585A DK165506C (da) 1984-01-12 1985-01-11 Proteinpraeparat med koagulationsaktivitet samt fremgangsmaade til fremstilling deraf
DK038892A DK169708B1 (da) 1984-01-12 1992-03-25 Komplex sonde, DNA-sekvens, som hybridiserer med sonden, og som koder for en fysiologisk aktiv del af faktor VIII:C, og ekstrachromosomalt element indeholdende en sådan DNA-sekvens
DK150992A DK169724B1 (da) 1984-01-12 1992-12-17 Fremgangsmåde til fremstilling af et polypeptidfragment af faktor VIII:C, DNA-sekvens, som koder herfor, og ekstrachromosomalt element indeholdende en sådan DNA-sekvens

Family Applications After (2)

Application Number Title Priority Date Filing Date
DK038892A DK169708B1 (da) 1984-01-12 1992-03-25 Komplex sonde, DNA-sekvens, som hybridiserer med sonden, og som koder for en fysiologisk aktiv del af faktor VIII:C, og ekstrachromosomalt element indeholdende en sådan DNA-sekvens
DK150992A DK169724B1 (da) 1984-01-12 1992-12-17 Fremgangsmåde til fremstilling af et polypeptidfragment af faktor VIII:C, DNA-sekvens, som koder herfor, og ekstrachromosomalt element indeholdende en sådan DNA-sekvens

Country Status (7)

Country Link
EP (3) EP0150735B2 (da)
JP (5) JPH0826078B2 (da)
AT (2) ATE224445T1 (da)
DE (6) DE3586402T3 (da)
DK (3) DK165506C (da)
LU (4) LU91014I2 (da)
NL (4) NL300118I2 (da)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4657894A (en) * 1983-03-31 1987-04-14 Scripps Clinic & Research Foundation New factor VIII coagulant polypeptides
JPH07106156B2 (ja) * 1983-10-28 1995-11-15 ジェネティックス、インスティチュ−ト ファクタ−▲viii▼および関連生産物の製造
US7138505B1 (en) 1984-01-12 2006-11-21 Novartis Vaccines And Diagnostics, Inc. Factor VIII:C nucleic acid molecules
ZA852099B (en) * 1984-03-26 1985-12-24 Meloy Lab Recombinant factor viii-c.
FI86885C (fi) * 1984-04-20 1992-10-26 Genentech Inc Foerfarande foer framstaellning av human rekombinantfaktor viii och nukleinsyrasekvenser och vektorer anvaend daertill
US4965199A (en) * 1984-04-20 1990-10-23 Genentech, Inc. Preparation of functional human factor VIII in mammalian cells using methotrexate based selection
EP0182448A3 (en) * 1984-08-24 1987-10-28 Genetics Institute, Inc. Production of factor viii and related products
SE8501050D0 (sv) * 1985-03-05 1985-03-05 Kabivitrum Ab Biologically active fragments of human antihemophilic factor and method for preparation thereof
EP0218712B1 (en) * 1985-04-12 1992-02-26 Genetics Institute, Inc. Novel procoagulant proteins
KR910006424B1 (ko) * 1985-08-21 1991-08-24 인코텍스 비.브이 편성브리프(brief) 제조방법
US5198349A (en) * 1986-01-03 1993-03-30 Genetics Institute, Inc. Method for producing factor VIII:C and analogs
FI98829C (fi) * 1986-01-27 1997-08-25 Chiron Corp Menetelmä rekombinoidun proteiinikompleksin valmistamiseksi, jolla on humaanitekijä VIII:C-aktiivisuutta
US5595886A (en) 1986-01-27 1997-01-21 Chiron Corporation Protein complexes having Factor VIII:C activity and production thereof
EP0251843A1 (fr) * 1986-06-06 1988-01-07 Transgene S.A. Procédé de préparation de facteur VIII à partir de cellules de mammifères
EP0272304B1 (en) * 1986-06-24 1994-01-26 Novo Nordisk A/S A process for producing a coagulation active complex of factor viii fragments
ATE63335T1 (de) 1986-07-11 1991-05-15 Miles Inc Herstellung von rekombinantem protein.
IL83192A (en) * 1986-07-18 1992-11-15 Gist Brocades Nv Method for the preparation of proteins with factor viii activity by microbial host cells;expression vectors,host cells,antibodies
IL84168A0 (en) * 1986-10-15 1988-03-31 Rorer Int Overseas Human factor viii-c analogs,process for the preparation thereof and pharmaceutical compositions containing the same
WO1988005825A1 (en) * 1987-01-30 1988-08-11 Biogen N.V. A method for producing factor viii in high yield
CA1339946C (en) * 1987-03-31 1998-07-07 Michael J. Griffith Ultrapurification process for polypeptides
EP0294910B1 (en) 1987-06-12 1996-09-11 Immuno Ag Novel proteins with factor VIII activity, process for their preparation using genetically engineered cells and pharmaceutical compositions containing them
DE3737239A1 (de) * 1987-11-03 1989-10-12 Behringwerke Ag Gentechnische herstellung von anticoagulatorischem protein pp4
US6544771B1 (en) * 1987-12-11 2003-04-08 Cell Genesys, Inc. Retroviral gene therapy vectors and therapeutic methods based thereon
US6140111A (en) * 1987-12-11 2000-10-31 Whitehead Institute For Biomedical Research Retroviral gene therapy vectors and therapeutic methods based thereon
CA2067158A1 (en) * 1989-09-14 1991-03-15 R. Alan Hardwick Method and useful apparatus for preparing pharmaceutical compositions
US5610033A (en) * 1990-04-25 1997-03-11 Novo Nordisk A/S Method of producing proteins with FVIII activity and/or FVIII derivatives
DK53792D0 (da) * 1992-04-24 1992-04-24 Novo Nordisk As Fremgangsmaade til fremstilling af proteiner
US5910481A (en) * 1995-11-13 1999-06-08 Immuno Ag Hybrid proteins with modified activity
US6500646B1 (en) * 1996-12-27 2002-12-31 Mochida Pharmaceutical Co., Ltd. Cell membrane-directed drugs
JP5149470B2 (ja) 1999-02-22 2013-02-20 バクスター・インターナショナル・インコーポレイテッド 新規のアルブミンを含有していない第viii因子処方物
EP1418810A4 (en) 2001-08-03 2006-08-02 Us Gov Health & Human Serv TREATMENT OF HEMOPHILIA ORAL
AU2003269557A1 (en) * 2002-10-18 2004-05-04 Lg Life Sciences Ltd. Gene families associated with cancers
EP1707634A1 (en) 2005-03-29 2006-10-04 Octapharma AG Method for isolation of recombinantly produced proteins
EP1739179A1 (en) 2005-06-30 2007-01-03 Octapharma AG Serum-free stable transfection and production of recombinant human proteins in human cell lines
NZ593190A (en) 2008-11-07 2013-01-25 Baxter Int Factor viii formulations
WO2011095604A1 (en) 2010-02-04 2011-08-11 Octapharma Biopharmaceuticals Gmbh Half-life prolongation of proteins

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4657894A (en) * 1983-03-31 1987-04-14 Scripps Clinic & Research Foundation New factor VIII coagulant polypeptides
IE80858B1 (en) * 1983-03-31 1999-04-21 Scripps Research Inst New factor viii coagulant polypeptides
US4663280A (en) * 1983-05-19 1987-05-05 Public Health Research Institute Of The City Of New York Expression and secretion vectors and method of constructing vectors
JPH07106156B2 (ja) * 1983-10-28 1995-11-15 ジェネティックス、インスティチュ−ト ファクタ−▲viii▼および関連生産物の製造
ZA852099B (en) * 1984-03-26 1985-12-24 Meloy Lab Recombinant factor viii-c.
FI86885C (fi) * 1984-04-20 1992-10-26 Genentech Inc Foerfarande foer framstaellning av human rekombinantfaktor viii och nukleinsyrasekvenser och vektorer anvaend daertill
JPH0634760A (ja) * 1992-07-15 1994-02-10 Hamamatsu Photonics Kk 放射線計測装置及び核医学診断装置

Also Published As

Publication number Publication date
EP0150735B2 (en) 2004-01-07
JP2002186487A (ja) 2002-07-02
LU91015I2 (fr) 2003-06-19
DK165506C (da) 1993-04-19
DE10399011I1 (de) 2003-10-23
EP0150735A2 (en) 1985-08-07
EP0466199A1 (en) 1992-01-15
LU91087I2 (fr) 2004-08-26
ATE224445T1 (de) 2002-10-15
DE10399009I1 (de) 2003-10-23
DK38892D0 (da) 1992-03-25
NL300153I1 (nl) 2004-09-01
DE10399010I1 (de) 2003-10-23
EP1006182A3 (en) 2000-06-14
NL300119I1 (nl) 2003-06-02
DE3588242D1 (de) 2002-10-31
NL300118I1 (nl) 2003-06-02
EP0150735B1 (en) 1992-07-29
EP1006182A2 (en) 2000-06-07
DE3586402D1 (de) 1992-09-03
JPH0826078B2 (ja) 1996-03-13
JPH06105688A (ja) 1994-04-19
NL300120I1 (nl) 2003-06-02
NL300118I2 (nl) 2004-06-01
DK13585A (da) 1985-09-11
JPH04218399A (ja) 1992-08-07
DK169708B1 (da) 1995-01-16
ATE78871T1 (de) 1992-08-15
LU91014I2 (fr) 2003-06-19
JP2000023670A (ja) 2000-01-25
DK150992A (da) 1992-12-17
JPH0634760B2 (ja) 1994-05-11
LU91013I2 (fr) 2003-06-19
DK38892A (da) 1992-03-25
DE3586402T2 (de) 1993-01-07
DK165506B (da) 1992-12-07
DK169724B1 (da) 1995-01-23
EP0466199B1 (en) 2002-09-18
EP0150735A3 (en) 1987-07-01
JPS60185723A (ja) 1985-09-21
DE122004000028I1 (de) 2004-09-30
DE3588242T2 (de) 2004-03-11
DE3586402T3 (de) 2004-12-23

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