RS49779B
(sr)
*
|
1998-01-12 |
2008-06-05 |
Glaxo Group Limited, |
Biciklična heteroaromatična jedinjenja kao inhibitori protein tirozin kinaze
|
MXPA03002410A
(es)
*
|
2000-09-20 |
2003-06-19 |
Merck Patent Gmbh |
4-amino-quinazolinas.
|
JP4458746B2
(ja)
*
|
2001-01-16 |
2010-04-28 |
グラクソ グループ リミテッド |
癌の治療方法
|
US7241763B2
(en)
|
2002-07-15 |
2007-07-10 |
Janssen Pharmaceutica N.V. |
3-furanyl analogs of toxoflavine as kinase inhibitors
|
WO2004041274A1
(en)
*
|
2002-11-05 |
2004-05-21 |
Arena Pharmaceuticals, Inc. |
Benzotriazoles and methods of prophylaxis or treatment of metabolic-related disorders thereof
|
EP1622587B1
(de)
*
|
2003-05-02 |
2010-04-28 |
Globopharm Pharmazeutische Produktions- und Handelsgesellschaft m.b.H. |
Feste pharmazeutische zubereitung enthaltend levothyroxin- und/oder liothyroninsalze
|
EA016558B1
(ru)
|
2003-06-17 |
2012-05-30 |
Арена Фармасьютикалз, Инк. |
Производные бензазепина, используемые для лечения заболеваний, ассоциированных с 5-ht-рецептором
|
EA200600071A1
(ru)
*
|
2003-06-20 |
2006-08-25 |
Арена Фармасьютикалз, Инк. |
Производные n-фенилпиперазина и способы профилактики или лечения заболеваний, связанных с 5ht-рецептором
|
US20060204966A1
(en)
|
2003-08-01 |
2006-09-14 |
Spector Neil L |
Treatment of cancers expressing p95 erbb2
|
US7501427B2
(en)
*
|
2003-08-14 |
2009-03-10 |
Array Biopharma, Inc. |
Quinazoline analogs as receptor tyrosine kinase inhibitors
|
MXPA06001767A
(es)
|
2003-08-14 |
2006-05-12 |
Array Biopharma Inc |
Analogos de quinazolina como inhibidores de la tirosina quinasa receptora.
|
TWI258478B
(en)
|
2003-10-31 |
2006-07-21 |
Arena Pharm Inc |
Tetrazole derivatives and methods of treatment of metabolic-related disorders thereof
|
UA83881C2
(en)
*
|
2003-12-18 |
2008-08-26 |
Янссен Фармацевтика Н.В. |
Pyrido- and pyrimidopyrimidine derivatives as anti-proliferative agents
|
BRPI0511754A
(pt)
*
|
2004-06-03 |
2008-01-02 |
Smithkline Beechman Cork Ltd |
uso de um composto ou sais ou solvatos do mesmo
|
US20090317383A1
(en)
*
|
2004-06-04 |
2009-12-24 |
Berger Mark S |
Cancer treatment method
|
EP1765313A2
(en)
|
2004-06-24 |
2007-03-28 |
Novartis Vaccines and Diagnostics, Inc. |
Compounds for immunopotentiation
|
JP2008511632A
(ja)
*
|
2004-08-27 |
2008-04-17 |
スミスクライン ビーチャム (コーク) リミテッド |
癌治療法
|
GB0427131D0
(en)
*
|
2004-12-10 |
2005-01-12 |
Glaxosmithkline Biolog Sa |
Novel combination
|
SG158168A1
(en)
*
|
2004-12-23 |
2010-01-29 |
Arena Pharm Inc |
5ht2c receptor modulator compositions and methods of use
|
US8735394B2
(en)
|
2005-02-18 |
2014-05-27 |
Abraxis Bioscience, Llc |
Combinations and modes of administration of therapeutic agents and combination therapy
|
PL3248600T3
(pl)
*
|
2005-02-18 |
2020-09-07 |
Abraxis Bioscience, Llc |
Połączenia i sposoby podawania środków terapeutycznych i terapia skojarzona
|
SI1871347T1
(sl)
*
|
2005-04-19 |
2016-11-30 |
Novartis Ag |
Farmacevtski sestavek
|
CA2632194C
(en)
|
2005-11-15 |
2012-01-03 |
Array Biopharma Inc. |
N4-phenyl-quinazoline-4-amine derivatives and related compounds as erbb type i receptor tyrosine kinase inhibitors for the treatment of hyperproliferative diseases
|
JO2660B1
(en)
|
2006-01-20 |
2012-06-17 |
نوفارتيس ايه جي |
Pi-3 inhibitors and methods of use
|
AR060358A1
(es)
|
2006-04-06 |
2008-06-11 |
Novartis Vaccines & Diagnostic |
Quinazolinas para la inhibicion de pdk 1
|
US20090203718A1
(en)
*
|
2006-04-13 |
2009-08-13 |
Smithkline Beecham (Cork) Ltd. |
Cancer treatment method
|
RU2008145225A
(ru)
|
2006-04-19 |
2010-05-27 |
Новартис АГ (CH) |
Соединения индазола и способы ингибирования cd7
|
JP5528806B2
(ja)
|
2006-10-12 |
2014-06-25 |
アステックス、セラピューティックス、リミテッド |
複合薬剤
|
JP5528807B2
(ja)
|
2006-10-12 |
2014-06-25 |
アステックス、セラピューティックス、リミテッド |
複合薬剤
|
CN101611041A
(zh)
|
2006-12-12 |
2009-12-23 |
武田药品工业株式会社 |
稠合杂环化合物
|
CN101245050A
(zh)
*
|
2007-02-14 |
2008-08-20 |
上海艾力斯医药科技有限公司 |
4-苯胺喹唑啉衍生物的盐
|
EP2166859A4
(en)
*
|
2007-06-11 |
2011-09-07 |
Smithkline Beecham Cork Ltd |
QUINAZOLINE SALT COMPOUNDS
|
EP2205076A4
(en)
*
|
2007-09-24 |
2010-12-29 |
Tragara Pharmaceuticals Inc |
POLYTHERAPY FOR THE TREATMENT OF CANCER USING COX-2 INHIBITORS AND DOUBLE INHIBITORS OF EGFR ÝERBB1 AND HER-2 ÝERBB2
|
WO2009079541A1
(en)
*
|
2007-12-18 |
2009-06-25 |
Smithkline Beecham (Cork) Limited |
Quinazoline ditosylate anhydrate forms
|
PA8809001A1
(es)
|
2007-12-20 |
2009-07-23 |
Novartis Ag |
Compuestos organicos
|
WO2009111004A1
(en)
*
|
2008-03-04 |
2009-09-11 |
Arena Pharmaceuticals, Inc. |
Processes for the preparation of intermediates related to the 5-ht2c agonist (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine
|
UY31704A
(es)
|
2008-03-12 |
2009-11-10 |
Takeda Pharmaceutical |
Compuesto heterociclico fusionado
|
EP2644204B1
(en)
|
2008-03-18 |
2017-04-19 |
Genentech, Inc. |
Combinations of an Anti-HER2 antibody-drug conjugate and pertuzumab
|
WO2009117352A1
(en)
*
|
2008-03-19 |
2009-09-24 |
Smithkline Beecham (Cork) Limited |
Cancer treatment method
|
WO2009137714A2
(en)
*
|
2008-05-07 |
2009-11-12 |
Teva Pharmaceutical Industries Ltd. |
Forms of lapatinib ditosylate and processes for preparation thereof
|
CN101584696A
(zh)
|
2008-05-21 |
2009-11-25 |
上海艾力斯医药科技有限公司 |
包含喹唑啉衍生物的组合物及制备方法、用途
|
WO2010017387A2
(en)
*
|
2008-08-06 |
2010-02-11 |
Teva Pharmaceutical Industries Ltd. |
Lapatinib intermediates
|
EP2158912A1
(en)
|
2008-08-25 |
2010-03-03 |
Ratiopharm GmbH |
Pharmaceutical composition comprising N-[3-chhloro-4-[3-fluorophenyl)methoxy)phenyl]6-[5[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furyl]-4-quinazolinamine
|
EP2158913A1
(en)
|
2008-08-25 |
2010-03-03 |
Ratiopharm GmbH |
Pharmaceutical composition comprising N-[3-chhloro-4-[(3-fluorophenyl)methoxy]phenyl]6-(5[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furyl]-4-quinazolinamine
|
US20100087459A1
(en)
*
|
2008-08-26 |
2010-04-08 |
Leonid Metsger |
Forms of lapatinib compounds and processes for the preparation thereof
|
WO2010061400A1
(en)
*
|
2008-11-03 |
2010-06-03 |
Natco Pharma Limited |
A novel process for the preparation of lapatinib and its pharmaceutically acceptable salts
|
CN101735200B
(zh)
*
|
2008-11-17 |
2013-01-02 |
岑均达 |
喹唑啉类化合物
|
US8293753B2
(en)
|
2009-07-02 |
2012-10-23 |
Novartis Ag |
Substituted 2-carboxamide cycloamino ureas
|
WO2011022633A2
(en)
|
2009-08-21 |
2011-02-24 |
Smithkline Beecham (Cork) Ltd. |
Method of threating cancer
|
ES2535176T3
(es)
|
2009-09-28 |
2015-05-06 |
Qilu Pharmaceutical Co., Ltd |
Derivados de 4-(anilino sustituido)quinazolina como inhibidores de la tirosina quinasa
|
US20120245351A1
(en)
*
|
2009-09-29 |
2012-09-27 |
Natco Pharma Limited |
Process for the preparation of lapatinib and its pharmaceutically acceptable salts
|
CN102079759B
(zh)
*
|
2009-12-01 |
2014-09-17 |
天津药物研究院 |
6位取代的喹唑啉类衍生物、其制备方法和用途
|
TW201129380A
(en)
|
2009-12-04 |
2011-09-01 |
Genentech Inc |
Methods of treating metastatic breast cancer with trastuzumab-MCC-DM1
|
US9682991B2
(en)
|
2009-12-31 |
2017-06-20 |
Fundación Centro Nacional De Investigaciones Oncologicas Carlos Iii |
Tricyclic compounds for use as kinase inhibitors
|
US9073927B2
(en)
|
2010-01-22 |
2015-07-07 |
Fundacion Centro Nacional De Investigaciones Oncologicas Carlos Iii |
Inhibitors of PI3 kinase
|
CA2790176A1
(en)
|
2010-02-18 |
2011-08-25 |
Centro Nacional De Investigaciones Oncologicas (Cnio) |
Triazolo [4, 5 - b] pyridin derivatives
|
AU2011232219B2
(en)
|
2010-03-23 |
2016-02-04 |
Scinopharm Taiwan, Ltd. |
Process and intermediates for preparing lapatinib
|
US8710221B2
(en)
|
2010-03-23 |
2014-04-29 |
Scinopharm Taiwan, Ltd. |
Process and intermediates for preparing lapatinib
|
NZ628423A
(en)
|
2010-03-29 |
2016-03-31 |
Abraxis Bioscience Llc |
Methods of treating cancer
|
KR20130028727A
(ko)
|
2010-03-29 |
2013-03-19 |
아브락시스 바이오사이언스, 엘엘씨 |
치료제의 약물 전달 및 유효성 향상 방법
|
WO2011121317A1
(en)
|
2010-04-01 |
2011-10-06 |
Centro Nacional De Investigaciones Oncologicas (Cnio) |
Imidazo [2,1-b] [1,3,4] thiadiazoles as protein or lipid kinase inhibitors
|
WO2011130831A1
(en)
*
|
2010-04-22 |
2011-10-27 |
Apotex Pharmachem Inc. |
Polymorphic forms of lapatinib ditosylate and processes for their preparation
|
ES2530755T3
(es)
*
|
2010-05-21 |
2015-03-05 |
Glaxosmithkline Llc |
Terapia de combinación para el tratamiento del cáncer
|
JP2013526578A
(ja)
|
2010-05-21 |
2013-06-24 |
グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー |
組合せ
|
WO2011153049A1
(en)
|
2010-06-02 |
2011-12-08 |
The Trustees Of The University Of Pennsylvania |
Methods and use of compounds that bind to her2/neu receptor complex
|
US9045431B2
(en)
|
2010-06-02 |
2015-06-02 |
Arena Pharmaceuticals, Inc. |
Processes for the preparation of 5-HT2C receptor agonists
|
WO2011153050A1
(en)
|
2010-06-02 |
2011-12-08 |
The Trustees Of The University Of Pennsylvania |
Methods and use of compounds that bind to her2/neu receptor complex
|
SG186112A1
(en)
|
2010-06-04 |
2013-01-30 |
Abraxis Bioscience Llc |
Methods of treatment of pancreatic cancer
|
CN102295638B
(zh)
*
|
2010-06-24 |
2014-07-09 |
齐鲁制药有限公司 |
拉帕替尼的制备方法
|
AR082418A1
(es)
|
2010-08-02 |
2012-12-05 |
Novartis Ag |
Formas cristalinas de 1-(4-metil-5-[2-(2,2,2-trifluoro-1,1-dimetil-etil)-piridin-4-il]-tiazol-2-il)-amida de 2-amida del acido (s)-pirrolidin-1,2-dicarboxilico
|
EP2601178A4
(en)
*
|
2010-08-03 |
2013-11-13 |
Hetero Research Foundation |
SALTS OF LAPATINIB
|
WO2012030939A1
(en)
|
2010-09-01 |
2012-03-08 |
Arena Pharmaceuticals, Inc. |
Administration of lorcaserin to individuals with renal impairment
|
WO2012030938A1
(en)
|
2010-09-01 |
2012-03-08 |
Arena Pharmaceuticals, Inc. |
Salts of lorcaserin with optically active acids
|
MX2013002421A
(es)
|
2010-09-01 |
2013-05-17 |
Arena Pharm Inc |
Sales no hidroscopicas de agonistas de 5-ht2c.
|
KR101913442B1
(ko)
|
2010-09-01 |
2018-10-30 |
에자이 알앤드디 매니지먼트 가부시키가이샤 |
체중 관리에 유용한 5-ht2c 작동제의 변형-방출 투여 형태
|
WO2012052745A1
(en)
|
2010-10-21 |
2012-04-26 |
Centro Nacional De Investigaciones Oncológicas (Cnio) |
Combinations of pi3k inhibitors with a second anti -tumor agent
|
BR112013013003A2
(pt)
|
2010-11-24 |
2016-08-09 |
Glaxo Group Ltd |
proteína de ligação de antígeno, e, composição farmacêutica
|
WO2012083440A1
(en)
|
2010-12-23 |
2012-06-28 |
Apotex Pharmachem Inc |
A process for the preparation of lapatinib and its ditosylate salt
|
WO2012098387A1
(en)
|
2011-01-18 |
2012-07-26 |
Centro Nacional De Investigaciones Oncológicas (Cnio) |
6, 7-ring-fused triazolo [4, 3 - b] pyridazine derivatives as pim inhibitors
|
PE20140293A1
(es)
|
2011-01-31 |
2014-03-19 |
Novartis Ag |
Novedosos derivados heterociclicos
|
KR20220031732A
(ko)
|
2011-03-04 |
2022-03-11 |
뉴젠 세러퓨틱스 인코포레이티드 |
알킨 치환된 퀴나졸린 화합물 및 그것의 사용 방법
|
US9321759B2
(en)
|
2011-03-17 |
2016-04-26 |
The Trustees Of The University Of Pennsylvania |
Methods and use of bifunctional enzyme-building clamp-shaped molecules
|
US9295676B2
(en)
|
2011-03-17 |
2016-03-29 |
The Trustees Of The University Of Pennsylvania |
Mutation mimicking compounds that bind to the kinase domain of EGFR
|
ITMI20110480A1
(it)
*
|
2011-03-25 |
2012-09-26 |
F I S Fabbrica Italiana Sint P A |
Procedimento per la preparazione di lapatinib e suoi sali
|
CN103635192B
(zh)
|
2011-04-01 |
2017-07-04 |
基因泰克公司 |
Akt抑制剂化合物和化疗剂的组合以及使用方法
|
WO2012155339A1
(zh)
*
|
2011-05-17 |
2012-11-22 |
江苏康缘药业股份有限公司 |
4-苯胺-6-丁烯酰胺-7-烷醚喹唑啉衍生物及其制备方法和用途
|
EP2524918A1
(en)
|
2011-05-19 |
2012-11-21 |
Centro Nacional de Investigaciones Oncológicas (CNIO) |
Imidazopyrazines derivates as kinase inhibitors
|
EP2710018B8
(en)
|
2011-05-19 |
2022-02-23 |
Fundación del Sector Público Estatal Centro Nacional de Investigaciones Oncológicas Carlos III (F.S.P. CNIO) |
Macrocyclic compounds as protein kinase inhibitors
|
ITMI20110894A1
(it)
|
2011-05-20 |
2012-11-21 |
Italiana Sint Spa |
Impurezza del lapatinib e suoi sali
|
CN102321076B
(zh)
*
|
2011-07-07 |
2013-08-21 |
中国科学技术大学 |
拉帕替尼中间体及其类似物的制备方法
|
WO2013004984A1
(en)
|
2011-07-07 |
2013-01-10 |
Centro Nacional De Investigaciones Oncologicas (Cnio) |
Tricyclic compounds for use as kinase inhibitors
|
WO2013005057A1
(en)
|
2011-07-07 |
2013-01-10 |
Centro Nacional De Investigaciones Oncológicas (Cnio) |
New compounds
|
WO2013005041A1
(en)
|
2011-07-07 |
2013-01-10 |
Centro Nacional De Investigaciones Oncológicas (Cnio) |
Tricyclic heterocyclic compounds as kinase inhibitors
|
EP2771342B1
(en)
|
2011-10-28 |
2016-05-18 |
Novartis AG |
Purine derivatives and their use in the treatment of disease
|
WO2013080218A1
(en)
|
2011-11-28 |
2013-06-06 |
Fresenius Kabi Oncology Ltd. |
Novel intermediates and process for the preparation of lapatinib and its pharmaceutically acceptable salts
|
AU2013214254B2
(en)
|
2012-01-31 |
2016-04-21 |
Novartis Ag |
Method of treating cancer
|
CN103304544B
(zh)
*
|
2012-03-06 |
2016-05-11 |
齐鲁制药有限公司 |
4-(取代苯胺基)喹唑啉衍生物二甲苯磺酸盐的多晶型物及其制备方法和用途
|
RU2660354C2
(ru)
|
2012-04-03 |
2018-07-05 |
Новартис Аг |
Комбинированные продукты, содержащие ингибиторы тирозинкиназ, и их применение
|
AU2013263043B2
(en)
|
2012-05-16 |
2016-06-16 |
Novartis Ag |
Dosage regimen for a PI-3 kinase inhibitor
|
AU2012392187B2
(en)
|
2012-10-09 |
2018-07-12 |
Arena Pharmaceuticals, Inc. |
Method of weight management
|
CZ2012712A3
(cs)
|
2012-10-17 |
2014-04-30 |
Zentiva, K.S. |
Nový způsob výroby klíčového intermediátu výroby lapatinibu
|
CN103819462B
(zh)
*
|
2012-11-19 |
2017-07-25 |
齐鲁制药有限公司 |
一种药用盐及其制备方法和用途
|
CN103819461B
(zh)
*
|
2012-11-19 |
2016-06-15 |
齐鲁制药有限公司 |
N-[3-氯-4-(3-氟苄氧基)苯基]-6-[5-[[2-(甲亚磺酰基)乙基]氨基]甲基]-2-呋喃基]-4-喹唑啉胺多晶型物及其制备方法
|
CN105732596B
(zh)
*
|
2012-11-19 |
2019-05-28 |
齐鲁制药有限公司 |
N-[3-氯-4-(3-氟苄氧基)苯基]-6-[5-[[2-(甲亚磺酰基)乙基]氨基]甲基]-2-呋喃基]-4-喹唑啉胺多晶型物及其制备方法
|
CN103896926A
(zh)
*
|
2012-12-27 |
2014-07-02 |
上海创诺医药集团有限公司 |
二对甲苯磺酸拉帕替尼溶剂化物多晶型物及其制法和用途
|
US9024023B2
(en)
|
2013-01-14 |
2015-05-05 |
F.I.S.—Fabbrica Italiana Sintetici S.p.A. |
Efficient process for the preparation of lapatinib and salts thereof by means of new intermediates
|
ITVI20130003A1
(it)
|
2013-01-14 |
2014-07-14 |
F I S Fabbrica Italiana Sint I S P A |
Procedimento per la preparazione di lapatinib e suoi sali mediante nuovi intermedi.
|
WO2014128107A1
(en)
|
2013-02-19 |
2014-08-28 |
Hexal Ag |
Pharmaceutical composition comprising n-[3-chloro-4-(3-fluorobenzyloxy)phenyl]-6-[5({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]quinazolin-4-amine or a pharmaceutically acceptable salt, solvate or solvated salt thereof
|
CN103159747A
(zh)
*
|
2013-02-26 |
2013-06-19 |
常州鸿创高分子科技有限公司 |
一种二对甲苯磺酸拉帕替尼的合成方法
|
US9468681B2
(en)
|
2013-03-01 |
2016-10-18 |
California Institute Of Technology |
Targeted nanoparticles
|
WO2014170910A1
(en)
|
2013-04-04 |
2014-10-23 |
Natco Pharma Limited |
Process for the preparation of lapatinib
|
CN104098517A
(zh)
*
|
2013-04-09 |
2014-10-15 |
上海科胜药物研发有限公司 |
一种制备拉帕替尼中间体的方法
|
HU231012B1
(hu)
|
2013-05-24 |
2019-11-28 |
Egis Gyógyszergyár Nyilvánosan Működő Részvénytársaság |
Lapatinib sók
|
TN2016000179A1
(en)
|
2013-12-06 |
2017-10-06 |
Novartis Ag |
Dosage regimen for an alpha-isoform selective phosphatidylinositol 3-kinase inhibitor.
|
CN104788434A
(zh)
*
|
2014-01-16 |
2015-07-22 |
江苏恒瑞医药股份有限公司 |
一种蛋白酪氨酸激酶抑制剂的二苯磺酸盐
|
US20160361309A1
(en)
|
2014-02-26 |
2016-12-15 |
Glaxosmithkline Intellectual Property (No.2) Limited |
Methods of treating cancer patients responding to ezh2 inhibitor gsk126
|
EP2937346A1
(en)
|
2014-04-24 |
2015-10-28 |
F.I.S.- Fabbrica Italiana Sintetici S.p.A. |
Co-crystals of lapatinib
|
ES2855075T3
(es)
|
2014-10-17 |
2021-09-23 |
Novartis Ag |
Combinación de ceritinib con un inhibidor de EGFR
|
MA41414A
(fr)
|
2015-01-28 |
2017-12-05 |
Centre Nat Rech Scient |
Protéines de liaison agonistes d' icos
|
CN107922609B
(zh)
|
2015-07-01 |
2020-04-24 |
加州理工学院 |
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|
DK3330267T3
(da)
|
2015-07-29 |
2022-03-14 |
Shionogi & Co |
Salt af quinazolinderivat eller crystal deraf samt fremgangsmåde til fremstilling af salt af quinazolinderivat eller crystal deraf
|
WO2017025871A1
(en)
|
2015-08-07 |
2017-02-16 |
Glaxosmithkline Intellectual Property Development Limited |
Combination therapy comprising anti ctla-4 antibodies
|
RU2018119085A
(ru)
|
2015-11-02 |
2019-12-04 |
Новартис Аг |
Схема введения ингибитора фосфатидилинозитол-3-киназы
|
US20190256608A1
(en)
|
2015-12-01 |
2019-08-22 |
Glaxosmithkline Intellectual Property Development Limited |
Combination treatments and uses and methods thereof
|
CN106892898B
(zh)
*
|
2015-12-18 |
2021-02-05 |
陕西师范大学 |
氮杂糖衍生化的喹唑啉类化合物
|
RU2603943C1
(ru)
*
|
2016-02-01 |
2016-12-10 |
Индивидуальный предприниматель Михайлов Олег Ростиславович |
КРИСТАЛЛИЧЕСКАЯ γ-МОДИФИКАЦИЯ N-{3-ХЛОР-4-[(3-ФТОРБЕНЗИЛ)ОКСИ] ФЕНИЛ}-6-[5-({[2-(МЕТАНСУЛЬФОНИЛ)ЭТИЛ]АМИНО}МЕТИЛ)-2-ФУРИЛ]-4-ХИНАЗОЛИНАМИНА БИС (4-МЕТИЛБЕНЗОЛСУЛЬФОНАТА) МОНОГИДРАТА, СПОСОБ ЕЁ ПОЛУЧЕНИЯ И ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ НА ЕЁ ОСНОВЕ
|
EP3266773B1
(en)
|
2016-07-04 |
2018-04-11 |
F.I.S.- Fabbrica Italiana Sintetici S.p.A. |
Process for the preparation of lapatinib ditosylate monohydrate by means of an improved crystallization procedure
|
EP3494140A1
(en)
|
2016-08-04 |
2019-06-12 |
GlaxoSmithKline Intellectual Property Development Ltd |
Anti-icos and anti-pd-1 antibody combination therapy
|
WO2018060833A1
(en)
|
2016-09-27 |
2018-04-05 |
Novartis Ag |
Dosage regimen for alpha-isoform selective phosphatidylinositol 3-kinase inhibitor alpelisib
|
WO2018139626A1
(ja)
|
2017-01-30 |
2018-08-02 |
塩野義製薬株式会社 |
キナゾリン誘導体を含有する固形製剤
|
EP3727387A4
(en)
|
2017-12-18 |
2021-12-15 |
Sterngreene, Inc. |
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|
WO2019241327A1
(en)
|
2018-06-13 |
2019-12-19 |
California Institute Of Technology |
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|
CN113924317A
(zh)
|
2019-02-01 |
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|
WO2020261097A1
(en)
|
2019-06-26 |
2020-12-30 |
Glaxosmithkline Intellectual Property Development Limited |
Il1rap binding proteins
|
WO2021043961A1
(en)
|
2019-09-06 |
2021-03-11 |
Glaxosmithkline Intellectual Property Development Limited |
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|
WO2021046293A1
(en)
|
2019-09-06 |
2021-03-11 |
Glaxosmithkline Intellectual Property Development Limited |
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|
CN115038466A
(zh)
|
2020-01-28 |
2022-09-09 |
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|