DK1294676T3 - Nye sammensætninger til stabilisering af nukleinsyrer i biologiske materialer - Google Patents

Nye sammensætninger til stabilisering af nukleinsyrer i biologiske materialer

Info

Publication number
DK1294676T3
DK1294676T3 DK01947306T DK01947306T DK1294676T3 DK 1294676 T3 DK1294676 T3 DK 1294676T3 DK 01947306 T DK01947306 T DK 01947306T DK 01947306 T DK01947306 T DK 01947306T DK 1294676 T3 DK1294676 T3 DK 1294676T3
Authority
DK
Denmark
Prior art keywords
nucleic acids
biological materials
stabilizing nucleic
new compositions
composition
Prior art date
Application number
DK01947306T
Other languages
Danish (da)
English (en)
Inventor
Vera Hollaender
Ralph Wyrich
Uwe Oelmueller
Original Assignee
Qiagen Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Qiagen Gmbh filed Critical Qiagen Gmbh
Application granted granted Critical
Publication of DK1294676T3 publication Critical patent/DK1294676T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/62—Quaternary ammonium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/62—Quaternary ammonium compounds
    • C07C211/63—Quaternary ammonium compounds having quaternised nitrogen atoms bound to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/62—Quaternary ammonium compounds
    • C07C211/64—Quaternary ammonium compounds having quaternised nitrogen atoms bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/54—Quaternary phosphonium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK01947306T 2000-06-27 2001-05-22 Nye sammensætninger til stabilisering af nukleinsyrer i biologiske materialer DK1294676T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10031236A DE10031236A1 (de) 2000-06-27 2000-06-27 Verwendung von Carbonsäuren und anderen Additiven in Kombination mit kationischen Verbindungen zur Stabilisierung von Nukleinsäuren in biologischen Materialien
PCT/EP2001/005888 WO2002000599A1 (de) 2000-06-27 2001-05-22 Neue kompositionen für die isolierung und/oder stabilisierung von nukleinsäuren in biologischen materialien

Publications (1)

Publication Number Publication Date
DK1294676T3 true DK1294676T3 (da) 2008-02-04

Family

ID=7646943

Family Applications (2)

Application Number Title Priority Date Filing Date
DK01947306T DK1294676T3 (da) 2000-06-27 2001-05-22 Nye sammensætninger til stabilisering af nukleinsyrer i biologiske materialer
DK07010591.1T DK1820793T3 (da) 2000-06-27 2001-05-22 Fremgangsmåde til stabilisering af nukleinsyrer i biologisk materiale

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK07010591.1T DK1820793T3 (da) 2000-06-27 2001-05-22 Fremgangsmåde til stabilisering af nukleinsyrer i biologisk materiale

Country Status (17)

Country Link
US (3) US7270953B2 (enExample)
EP (3) EP1820793B1 (enExample)
JP (5) JP5795455B2 (enExample)
CN (1) CN1250520C (enExample)
AT (3) ATE524431T1 (enExample)
AU (4) AU2001269031B2 (enExample)
BR (1) BR0112002A (enExample)
CA (2) CA2412534C (enExample)
CZ (1) CZ20024129A3 (enExample)
DE (3) DE10031236A1 (enExample)
DK (2) DK1294676T3 (enExample)
ES (2) ES2295177T3 (enExample)
HU (1) HUP0301342A2 (enExample)
MX (1) MXPA02012261A (enExample)
PL (1) PL360705A1 (enExample)
SK (1) SK18022002A3 (enExample)
WO (2) WO2002000599A1 (enExample)

Families Citing this family (82)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080064108A1 (en) * 1997-12-10 2008-03-13 Tony Baker Urine Preservation System
US7569342B2 (en) 1997-12-10 2009-08-04 Sierra Molecular Corp. Removal of molecular assay interferences
DE10031236A1 (de) * 2000-06-27 2002-01-10 Qiagen Gmbh Verwendung von Carbonsäuren und anderen Additiven in Kombination mit kationischen Verbindungen zur Stabilisierung von Nukleinsäuren in biologischen Materialien
EP1356302B1 (en) * 2000-11-08 2008-01-23 Becton Dickinson and Company Method and device for collecting and stabilizing a biological sample
US6602718B1 (en) * 2000-11-08 2003-08-05 Becton, Dickinson And Company Method and device for collecting and stabilizing a biological sample
DE10147439B4 (de) * 2001-09-26 2014-01-30 Qiagen Gmbh Verfahren zur Isolierung von DNA aus biologischen Proben
EP1329506A1 (en) 2002-01-18 2003-07-23 Cypro S.A. Method to quantify in vivo RNA levels
DE10208005A1 (de) * 2002-02-26 2003-09-04 Qiagen Gmbh Verfahren zur Änderung der Transkriptkonzentration in ribonukleinsäurehaltigen biologischen Proben
US7482116B2 (en) 2002-06-07 2009-01-27 Dna Genotek Inc. Compositions and methods for obtaining nucleic acids from sputum
DE10336177B4 (de) * 2002-08-09 2010-02-11 Alexander Cherkasky Verwendung von Zellorganellen zur Stabilisierung von Nukleinsäuren und Zellen
WO2004020626A1 (de) * 2002-08-09 2004-03-11 Alexander Cherkasky Verwendung von zellorganellen zur stabilisierung von biomolekülen und zellen
JP2006502857A (ja) * 2002-10-18 2006-01-26 プロメガ コーポレイション 分子を分離するための方法
JP2006528482A (ja) * 2003-07-24 2006-12-21 キアゲン ゲゼルシャフト ミット ベシュレンクテル ハフツング 核酸の逆転写及び/または増幅方法
US20050059024A1 (en) 2003-07-25 2005-03-17 Ambion, Inc. Methods and compositions for isolating small RNA molecules
GB0327319D0 (en) * 2003-11-24 2003-12-24 Pfizer Ltd Novel pharmaceuticals
US20070196826A1 (en) * 2004-03-23 2007-08-23 Hiroyuki Ohno Solvent For Dissolving Nucleic Acid, Nucleic Acid-Containing Solution And Method Of Preserving Nucleic Acid
WO2005113147A2 (en) 2004-04-08 2005-12-01 Biomatrica, Inc. Integration of sample storage and sample management for life science
US20080176209A1 (en) * 2004-04-08 2008-07-24 Biomatrica, Inc. Integration of sample storage and sample management for life science
US20060099567A1 (en) * 2004-04-08 2006-05-11 Biomatrica, Inc. Integration of sample storage and sample management for life science
DE102004023417A1 (de) * 2004-05-12 2005-12-08 Clariant Gmbh Verfahren zur Herstellung von langkettigen quaternären Ammonium-oxalaten und -hydrogenoxalaten
JP4810164B2 (ja) * 2004-09-03 2011-11-09 富士フイルム株式会社 核酸分離精製方法
US20060094023A1 (en) * 2004-11-02 2006-05-04 Industrial Technology Research Institute Method for isolating nucleic acid by using amino surfactants
TWI294460B (en) * 2004-12-23 2008-03-11 Ind Tech Res Inst Method for stabilizing nucleic acids
DE102005015005A1 (de) * 2005-04-01 2006-10-05 Qiagen Gmbh Verfahren zur Behandlung einer Biomoleküle enthaltenden Probe
US20060234251A1 (en) * 2005-04-19 2006-10-19 Lumigen, Inc. Methods of enhancing isolation of RNA from biological samples
US20070015165A1 (en) * 2005-07-13 2007-01-18 Sigma-Aldrich Co. Method for the isolation of RNA from biological sources
US20070190526A1 (en) * 2006-02-16 2007-08-16 Nexgen Diagnostics Llc Methods of extracting nucleic acids
EP2022853A4 (en) * 2006-05-17 2010-03-10 Yoshiyuki Koyama FREEZERED PRODUCT FOR THE TRANSFER OF NUCLEIC ACID, OLIGONUCLEIC ACID OR DERIVATIVES THEREOF
DE102007016707A1 (de) * 2007-04-04 2008-10-09 Qiagen Gmbh Verfahren zur Aufreinigung von Biomolekülen
DE102007025277A1 (de) 2007-05-31 2008-12-04 Qiagen Gmbh Verfahren zur Stabilisierung einer biologischen Probe
DE102007025275A1 (de) 2007-05-31 2008-12-04 Qiagen Gmbh Butendisäure oder deren Derivate zur Behandlung einer biologischen Probe
DE102007025276A1 (de) 2007-05-31 2008-12-04 Qiagen Gmbh Aromatische Alkohole zur Behandlung einer biologischen Probe
US20090053704A1 (en) * 2007-08-24 2009-02-26 Natalia Novoradovskaya Stabilization of nucleic acids on solid supports
US7687027B2 (en) * 2008-02-27 2010-03-30 Becton, Dickinson And Company Cleaning compositions, methods and materials for reducing nucleic acid contamination
AU2010227509A1 (en) 2009-03-27 2011-09-08 Universite Libre De Bruxelles New marker for diagnosis of active multiple sclerosis
WO2011051402A1 (en) 2009-11-02 2011-05-05 Universite Libre De Bruxelles New biomarkers for determining allergy status
EP2345719A1 (en) 2010-01-18 2011-07-20 Qiagen GmbH Method for isolating small RNA
US8932809B2 (en) * 2010-01-19 2015-01-13 Opgen, Inc. Methods and kits for isolating nucleic acid from an organism
WO2011157678A1 (en) 2010-06-14 2011-12-22 Qiagen Gmbh Method for determination of target cells or tissue for extraction of biomolecules from fixed biological samples
EP2407540A1 (en) 2010-07-15 2012-01-18 Qiagen GmbH Method for purifying a target nucleic acid
US9376709B2 (en) 2010-07-26 2016-06-28 Biomatrica, Inc. Compositions for stabilizing DNA and RNA in blood and other biological samples during shipping and storage at ambient temperatures
EP2598661B1 (en) 2010-07-26 2017-09-27 Biomatrica, INC. Compositions for stabilizing dna, rna and proteins in saliva and other biological samples during shipping and storage at ambient temperatures
CN102146422B (zh) * 2011-01-24 2013-08-07 南京工业大学 一种丁二酸的发酵生产工艺
EP3246416B1 (en) 2011-04-15 2024-06-05 The Johns Hopkins University Safe sequencing system
US9442046B2 (en) 2011-06-19 2016-09-13 Abogen, Inc. Device for sample collection
JP6096774B2 (ja) 2011-08-12 2017-03-15 キアゲン ゲゼルシャフト ミット ベシュレンクテル ハフツング 核酸を単離するための方法
AU2012314514B2 (en) 2011-09-26 2018-03-15 Qiagen Gmbh Stabilisation and isolation of extracellular nucleic acids
US11021733B2 (en) 2011-09-26 2021-06-01 Qiagen Gmbh Stabilization and isolation of extracellular nucleic acids
WO2013045458A1 (en) 2011-09-26 2013-04-04 Preanalytix Gmbh Stabilisation and isolation of extracellular nucleic acids
JP6333737B2 (ja) 2012-02-09 2018-05-30 ライフ テクノロジーズ コーポレーション コンジュゲートされたポリマー粒子およびその製造方法
ES2567091T3 (es) 2012-04-05 2016-04-19 F. Hoffmann-La Roche Ag Compuestos de amina para la preparación selectiva de muestras biológicas
US10233508B2 (en) 2012-08-21 2019-03-19 Qiagen Gmbh Virus particle stabilisation and method for isolating viral nucleic acids
EP2888363B1 (en) 2012-08-21 2018-06-06 Qiagen GmbH Method for isolating nucleic acids from a formaldehyde releaser stabilized sample
AU2013310861B2 (en) * 2012-09-03 2019-02-14 Qiagen Gmbh Method for isolating RNA including small RNA with high yield
JP6608280B2 (ja) 2012-09-25 2019-11-20 キアゲン ゲーエムベーハー 生物学的試料の安定化
WO2014070462A1 (en) 2012-10-29 2014-05-08 The Johns Hopkins University Papanicolaou test for ovarian and endometrial cancers
US9725703B2 (en) 2012-12-20 2017-08-08 Biomatrica, Inc. Formulations and methods for stabilizing PCR reagents
ES2677723T3 (es) 2012-12-28 2018-08-06 Cellestis Limited Un ensayo de la respuesta inmunológica mediada por células
GB201303666D0 (en) 2013-03-01 2013-04-17 Goldsborough Andrew S Sample fixation and stabilisation
EP2976424B1 (en) 2013-03-18 2018-10-03 Qiagen GmbH Stabilisation of biological samples
US20160281133A1 (en) 2013-03-18 2016-09-29 Qiagen Gmbh Stabilization and isolation of extracellular nucleic acids
GB201305414D0 (en) 2013-03-25 2013-05-08 Arcis Biotechnology Holdings Ltd Method and composition
KR102392407B1 (ko) 2014-03-07 2022-04-29 디엔에이 제노텍 인코퍼레이티드 생물학적 샘플에서 핵산을 안정화하기 위한 조성물 및 방법
CA2940692C (en) 2014-03-18 2025-07-08 Qiagen Gmbh STABILIZATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS
WO2015191632A1 (en) 2014-06-10 2015-12-17 Biomatrica, Inc. Stabilization of thrombocytes at ambient temperatures
CN107208032A (zh) 2014-09-17 2017-09-26 豪洛捷公司 部分裂解和测定的方法
CN107667168A (zh) 2015-05-27 2018-02-06 凯杰有限公司 用于破碎组织材料的组合物和方法
EP3317426B1 (en) 2015-07-02 2020-01-15 Life Technologies Corporation Conjugation of carboxyl functional hydrophilic beads
WO2017007774A1 (en) 2015-07-06 2017-01-12 Life Technologies Corporation Substrates and methods useful in sequencing
US11286531B2 (en) 2015-08-11 2022-03-29 The Johns Hopkins University Assaying ovarian cyst fluid
JP7166169B2 (ja) 2015-11-20 2022-11-07 キアゲン ゲーエムベーハー 細胞外核酸の滅菌のための滅菌組成物を調製する方法
ES2946184T3 (es) 2015-12-08 2023-07-13 Biomatrica Inc Reducción de la velocidad de eritrosedimentación
CN110191960A (zh) * 2016-11-08 2019-08-30 克维拉公司 进行核酸稳定和分离的方法
PT3568475T (pt) 2017-01-16 2023-04-18 Spectrum Solutions L L C Solução de preservação de ácido nucleico e métodos de utilização
KR20250047324A (ko) 2017-08-07 2025-04-03 더 존스 홉킨스 유니버시티 암을 평가하고 치료하기 위한 방법 및 재료
CN110012899A (zh) * 2019-04-12 2019-07-16 南京科佰生物科技有限公司 细胞用rna稳定剂及其使用方法
WO2021163546A1 (en) 2020-02-14 2021-08-19 The Johns Hopkins University Methods and materials for assessing nucleic acids
CN116529371A (zh) * 2020-05-29 2023-08-01 洛克菲勒大学 从自收集小体积样品中分离rna的方法和系统
KR20230018435A (ko) * 2020-05-29 2023-02-07 더 락커펠러 유니버시티 자기-수집된 및 작은 부피 샘플로부터의 rna 단리를 위한 방법 및 시스템
US20250075035A1 (en) 2021-12-10 2025-03-06 Nitto Boseki Co., Ltd. Agent for raising melting temperature (tm value) of nucleic acid
KR102728359B1 (ko) * 2021-12-10 2024-11-11 니토 보세키 가부시기가이샤 2 본쇄 핵산의 융해 온도 상승화제 및 그 용도
KR102786563B1 (ko) 2023-04-27 2025-03-26 전남대학교산학협력단 수송배지로서 혈액 내의 핵산 보존용 조성물 및 이를 이용한 핵산의 보존방법

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2099266A5 (enExample) 1970-06-22 1972-03-10 Shell Int Research
US4900677A (en) * 1986-09-26 1990-02-13 E. I. Du Pont De Nemours And Company Process for rapid isolation of high molecular weight DNA
US5010183A (en) 1989-07-07 1991-04-23 Macfarlane Donald E Process for purifying DNA and RNA using cationic detergents
IT1240870B (it) 1990-02-14 1993-12-17 Talent Procedimento per l'estrazione e la purificazione di dna genomico umano
US5196182A (en) 1991-05-08 1993-03-23 Streck Laboratories, Inc. Tissue fixative
US5260048A (en) 1991-05-08 1993-11-09 Streck Laboratories, Inc. Tissue fixative solution and method
US5275708A (en) * 1992-03-20 1994-01-04 Thomas Jefferson University Cetyltrimethylammonium bromide gel electrophoresis
CA2107939C (en) * 1993-01-13 2001-01-30 Stephen B. Kong Acidic aqueous cleaning compositions
AU6230594A (en) * 1993-02-01 1994-08-29 University Of Iowa Research Foundation, The Quartenary amine surfactants and methods of using same in isolation of rna
US5300635A (en) * 1993-02-01 1994-04-05 University Of Iowa Research Foundation Quaternary amine surfactants and methods of using same in isolation of nucleic acids
US5300645A (en) 1993-04-14 1994-04-05 Eli Lilly And Company Tetrahydro-pyrido-indole
US5641726A (en) 1993-06-09 1997-06-24 Lonza, Inc. Quaternary ammonium carboxylate and borate compositions and preparation thereof
ZA943999B (en) * 1993-06-09 1995-02-03 Lonza Ag Quaternary ammonium and waterproofing/preservative compositions
EP0743950B1 (de) 1994-02-11 2001-12-12 QIAGEN GmbH Verfahren zur trennung von doppelstrang/einzelstrangnukleinsäurestrukturen
JP2001526051A (ja) 1997-12-10 2001-12-18 シエラ ダイアグノスティクス,インク. 体液中のdnaを保存するための方法及び試薬
EP1041996A4 (en) * 1997-12-22 2003-05-14 Human Genome Sciences Inc KERATINOCYTE GROWTH FACTOR-2 FORMULATIONS
US6204375B1 (en) * 1998-07-31 2001-03-20 Ambion, Inc. Methods and reagents for preserving RNA in cell and tissue samples
US7683035B1 (en) * 1999-02-23 2010-03-23 Qiagen, Gmbh Method of stabilizing and/or isolating nucleic acids
DE10031236A1 (de) * 2000-06-27 2002-01-10 Qiagen Gmbh Verwendung von Carbonsäuren und anderen Additiven in Kombination mit kationischen Verbindungen zur Stabilisierung von Nukleinsäuren in biologischen Materialien

Also Published As

Publication number Publication date
MXPA02012261A (es) 2004-09-06
ATE394363T1 (de) 2008-05-15
AU6903101A (en) 2002-01-08
DK1820793T3 (da) 2012-01-02
JP2015027310A (ja) 2015-02-12
CA2410388C (en) 2014-12-09
JP2004501621A (ja) 2004-01-22
EP1296932B1 (de) 2008-05-07
JP5795455B2 (ja) 2015-10-14
JP5657847B2 (ja) 2015-01-21
CN1250520C (zh) 2006-04-12
AU7568501A (en) 2002-01-08
EP1820793B1 (de) 2011-09-14
EP1820793A1 (de) 2007-08-22
US7270953B2 (en) 2007-09-18
ES2295177T3 (es) 2008-04-16
JP2015212273A (ja) 2015-11-26
US7682790B2 (en) 2010-03-23
CA2412534C (en) 2011-08-09
AU2007201583B2 (en) 2010-06-03
HUP0301342A2 (hu) 2003-08-28
SK18022002A3 (sk) 2003-07-01
US20040014703A1 (en) 2004-01-22
CA2412534A1 (en) 2002-12-17
ES2373784T3 (es) 2012-02-08
EP1296932A1 (de) 2003-04-02
EP1294676B1 (de) 2007-10-03
ATE524431T1 (de) 2011-09-15
US20030165943A1 (en) 2003-09-04
CZ20024129A3 (cs) 2003-06-18
PL360705A1 (en) 2004-09-20
EP1294676A1 (de) 2003-03-26
ATE374743T1 (de) 2007-10-15
AU2007201583A1 (en) 2007-05-03
JP2012135317A (ja) 2012-07-19
WO2002000600A1 (de) 2002-01-03
CN1438988A (zh) 2003-08-27
DE10031236A1 (de) 2002-01-10
JP2004501622A (ja) 2004-01-22
WO2002000599A1 (de) 2002-01-03
BR0112002A (pt) 2003-05-13
US20080071072A1 (en) 2008-03-20
AU783922B2 (en) 2005-12-22
DE50113086D1 (de) 2007-11-15
CA2410388A1 (en) 2002-11-28
AU2001269031B2 (en) 2007-01-11
US6861213B2 (en) 2005-03-01
DE50113941D1 (de) 2008-06-19

Similar Documents

Publication Publication Date Title
DK1820793T3 (da) Fremgangsmåde til stabilisering af nukleinsyrer i biologisk materiale
ATE496997T1 (de) Verfahren zur stabilisierung und/oder isolierung von nukleinsäuren
ATE522580T1 (de) Cyaninfarbstoffe als markieragenzien
MXPA05006907A (es) Compuestos diazoicos cationicos, composiciones que los contienen como colorante directo, procedimiento de coloracion de fibras queratinicas y dispositivo.
AR042420A1 (es) Benzotriazolil- aminoacetonitril compuestos, proceso para su preparacion, metodo y uso de los mismos en el control de endo- y ecto-parasitos dentro y sobre ganado productor de sangre caliente y animales domesticos y plantas, y en la preparacion de una composicion farmaceutica
AR042943A1 (es) Insecticidas de ciano antranilamida
PT88992A (pt) Processo para a preparacao de compostos contendo fosforo uteis como inibidores de colagenase
ATE278322T1 (de) Mittel zur bekämpfung von pflanzenschädlingen
ES2172774T3 (es) Composiciones y procedimiento para el tratamiento de plantas con sustancias quimicas exogenas.
DE69821376D1 (de) Verfahren zur proteinrückfaltung durch verwendung zwitterionischer wirkstoffe von niedrigem molekulargewicht
AR035531A1 (es) Composicion para el control de plagas endoparasiticas en ganados y animales domesticos, un metodo para su control y el uso de dicha composicion para la preparacion de medicamentos
DE69921151D1 (de) Fluorszierende marker
BRPI0411308A8 (pt) Composto, composição farmacêutica, processo para a preparação de um composto, e, uso de um composto
AR040149A1 (es) Compuestos de aminoacetonitrilo, un proceso para su preparacion, composicion, y uso del compuesto
ATE501270T1 (de) Nukleinsäure-extraktion-lösung und gebrauch davon
ATE546539T1 (de) Revertierung der negativ-selektiven wirkung von negativen markerproteinen als selektionsverfahren
EA200800752A1 (ru) Стабильные при хранении препараты сульфонамидов
ES543787A0 (es) Procedimiento de preparacion de nuevos derivados a-etilben- zol con un grupo piridinometoxi sustituido y de sus sales deadicion acidas y cuaternarias
DE3765765D1 (de) Polymere als beizmittel fuer saure farbstoffe.
DK1280812T3 (da) Cyclipostiner, fremgangsmåde til deres fremstilling og anvendelse af samme
NO996179D0 (no) Nye 1,2-ditiolanforbindelser, en fremgangsmåte for deres fremstilling og farmasoeytiske blandinger inneholdende disse
DE50105413D1 (de) Verfahren zur Racemisierung von optisch aktiven Aminen
ATE294155T1 (de) Eine methode zur herstellung von verbindungen der formel 1 und derivaten
ES8403448A1 (es) Un procedimiento para la preparacion de derivados de aminoacido.
DE50110250D1 (de) Verfahren zur herstellung von 3-aminoalkansäureestern