HUP0301342A2 - Kationos vegyületeket és protondonort tartalmazó készítmények alkalmazása nukleinsavak stabilizálására és/vagy izolálására mikroorganizmusokból, például prokariotákból, gombákból, protozoonokból vagy algákból - Google Patents

Kationos vegyületeket és protondonort tartalmazó készítmények alkalmazása nukleinsavak stabilizálására és/vagy izolálására mikroorganizmusokból, például prokariotákból, gombákból, protozoonokból vagy algákból

Info

Publication number
HUP0301342A2
HUP0301342A2 HU0301342A HUP0301342A HUP0301342A2 HU P0301342 A2 HUP0301342 A2 HU P0301342A2 HU 0301342 A HU0301342 A HU 0301342A HU P0301342 A HUP0301342 A HU P0301342A HU P0301342 A2 HUP0301342 A2 HU P0301342A2
Authority
HU
Hungary
Prior art keywords
nucleic acids
preparation
protozoa
algae
fungi
Prior art date
Application number
HU0301342A
Other languages
English (en)
Inventor
Uwe Oelmüller
Tanja Wille
Original Assignee
Qiagen Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Qiagen Gmbh filed Critical Qiagen Gmbh
Publication of HUP0301342A2 publication Critical patent/HUP0301342A2/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/62Quaternary ammonium compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/62Quaternary ammonium compounds
    • C07C211/63Quaternary ammonium compounds having quaternised nitrogen atoms bound to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/62Quaternary ammonium compounds
    • C07C211/64Quaternary ammonium compounds having quaternised nitrogen atoms bound to carbon atoms of six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/54Quaternary phosphonium compounds

Abstract

A találmány tárgyát kationos vegyületet és adalékanyagkéntprotondonort tartalmazó készítmények alkalmazása képezi nukleinsavakstabilizálására és/vagy izolálására. Ezen felül, a találmány tárgyátképezi egy eljárás is a készítmény előállítására, valamint akészítményt tartalmazó diagnosztikus készítmény és reagenskészlet,továbbá a készítményt és biológiai mintát tartalmazó elegy. Akészítmény alkalmas nukleinsavak izolálására mikroorganizmusokból,például prokariotákból, gombákból, protozoonokból vagy algákból,és/vagy a nukleinsavak stabilizálására. Ó
HU0301342A 2000-06-27 2001-06-26 Kationos vegyületeket és protondonort tartalmazó készítmények alkalmazása nukleinsavak stabilizálására és/vagy izolálására mikroorganizmusokból, például prokariotákból, gombákból, protozoonokból vagy algákból HUP0301342A2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10031236A DE10031236A1 (de) 2000-06-27 2000-06-27 Verwendung von Carbonsäuren und anderen Additiven in Kombination mit kationischen Verbindungen zur Stabilisierung von Nukleinsäuren in biologischen Materialien
PCT/EP2001/007281 WO2002000600A1 (de) 2000-06-27 2001-06-26 Verwendung von kompositionen aus kationischen verbindungen und protonendonoren zur stabilisierung und/oder isolierung von nukleinsäuren in bzw. aus mikroorganismen - wie prokaryonten, pilzen, protozoen oder algen

Publications (1)

Publication Number Publication Date
HUP0301342A2 true HUP0301342A2 (hu) 2003-08-28

Family

ID=7646943

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0301342A HUP0301342A2 (hu) 2000-06-27 2001-06-26 Kationos vegyületeket és protondonort tartalmazó készítmények alkalmazása nukleinsavak stabilizálására és/vagy izolálására mikroorganizmusokból, például prokariotákból, gombákból, protozoonokból vagy algákból

Country Status (17)

Country Link
US (3) US7270953B2 (hu)
EP (3) EP1294676B1 (hu)
JP (5) JP5795455B2 (hu)
CN (1) CN1250520C (hu)
AT (3) ATE524431T1 (hu)
AU (4) AU2001269031B2 (hu)
BR (1) BR0112002A (hu)
CA (2) CA2412534C (hu)
CZ (1) CZ20024129A3 (hu)
DE (3) DE10031236A1 (hu)
DK (2) DK1294676T3 (hu)
ES (2) ES2295177T3 (hu)
HU (1) HUP0301342A2 (hu)
MX (1) MXPA02012261A (hu)
PL (1) PL360705A1 (hu)
SK (1) SK18022002A3 (hu)
WO (2) WO2002000599A1 (hu)

Families Citing this family (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080064108A1 (en) * 1997-12-10 2008-03-13 Tony Baker Urine Preservation System
US7569342B2 (en) * 1997-12-10 2009-08-04 Sierra Molecular Corp. Removal of molecular assay interferences
DE10031236A1 (de) * 2000-06-27 2002-01-10 Qiagen Gmbh Verwendung von Carbonsäuren und anderen Additiven in Kombination mit kationischen Verbindungen zur Stabilisierung von Nukleinsäuren in biologischen Materialien
US6602718B1 (en) * 2000-11-08 2003-08-05 Becton, Dickinson And Company Method and device for collecting and stabilizing a biological sample
CN100386441C (zh) * 2000-11-08 2008-05-07 贝克顿迪肯森公司 收集和稳定生物样品的装置、抑制体外基因诱导的方法和制备全血样品的方法
DE10147439B4 (de) * 2001-09-26 2014-01-30 Qiagen Gmbh Verfahren zur Isolierung von DNA aus biologischen Proben
EP1329506A1 (en) 2002-01-18 2003-07-23 Cypro S.A. Method to quantify in vivo RNA levels
DE10208005A1 (de) * 2002-02-26 2003-09-04 Qiagen Gmbh Verfahren zur Änderung der Transkriptkonzentration in ribonukleinsäurehaltigen biologischen Proben
US7482116B2 (en) 2002-06-07 2009-01-27 Dna Genotek Inc. Compositions and methods for obtaining nucleic acids from sputum
DE10336177B4 (de) * 2002-08-09 2010-02-11 Alexander Cherkasky Verwendung von Zellorganellen zur Stabilisierung von Nukleinsäuren und Zellen
WO2004020626A1 (de) * 2002-08-09 2004-03-11 Alexander Cherkasky Verwendung von zellorganellen zur stabilisierung von biomolekülen und zellen
CN1852765A (zh) * 2002-10-18 2006-10-25 普罗梅加公司 用于分离分子的组合物
US20060281092A1 (en) * 2003-07-24 2006-12-14 Tanja Wille Method for the reverse transcription and/or amplification of nucleic acids
US20050059024A1 (en) 2003-07-25 2005-03-17 Ambion, Inc. Methods and compositions for isolating small RNA molecules
GB0327319D0 (en) * 2003-11-24 2003-12-24 Pfizer Ltd Novel pharmaceuticals
EP1736542A4 (en) * 2004-03-23 2008-10-29 Hiroyuki Ohno SOLVENTS FOR SOLVING NUCLEIC ACID, NUCLEIC ACIDIC SOLUTION, AND METHOD FOR PRESERVING NUCLEIC ACID
US20060099567A1 (en) * 2004-04-08 2006-05-11 Biomatrica, Inc. Integration of sample storage and sample management for life science
US20080176209A1 (en) * 2004-04-08 2008-07-24 Biomatrica, Inc. Integration of sample storage and sample management for life science
EP1737573A2 (en) 2004-04-08 2007-01-03 Biomatrica, Inc. Integration of sample storage and sample management for life science
DE102004023417A1 (de) * 2004-05-12 2005-12-08 Clariant Gmbh Verfahren zur Herstellung von langkettigen quaternären Ammonium-oxalaten und -hydrogenoxalaten
JP4810164B2 (ja) * 2004-09-03 2011-11-09 富士フイルム株式会社 核酸分離精製方法
US20060094023A1 (en) * 2004-11-02 2006-05-04 Industrial Technology Research Institute Method for isolating nucleic acid by using amino surfactants
TWI294460B (en) * 2004-12-23 2008-03-11 Ind Tech Res Inst Method for stabilizing nucleic acids
DE102005015005A1 (de) * 2005-04-01 2006-10-05 Qiagen Gmbh Verfahren zur Behandlung einer Biomoleküle enthaltenden Probe
US20060234251A1 (en) * 2005-04-19 2006-10-19 Lumigen, Inc. Methods of enhancing isolation of RNA from biological samples
US20070015165A1 (en) * 2005-07-13 2007-01-18 Sigma-Aldrich Co. Method for the isolation of RNA from biological sources
US20070190526A1 (en) * 2006-02-16 2007-08-16 Nexgen Diagnostics Llc Methods of extracting nucleic acids
EP2022853A4 (en) * 2006-05-17 2010-03-10 Yoshiyuki Koyama FREEZERED PRODUCT FOR THE TRANSFER OF NUCLEIC ACID, OLIGONUCLEIC ACID OR DERIVATIVES THEREOF
DE102007016707A1 (de) * 2007-04-04 2008-10-09 Qiagen Gmbh Verfahren zur Aufreinigung von Biomolekülen
DE102007025275A1 (de) 2007-05-31 2008-12-04 Qiagen Gmbh Butendisäure oder deren Derivate zur Behandlung einer biologischen Probe
DE102007025277A1 (de) 2007-05-31 2008-12-04 Qiagen Gmbh Verfahren zur Stabilisierung einer biologischen Probe
DE102007025276A1 (de) 2007-05-31 2008-12-04 Qiagen Gmbh Aromatische Alkohole zur Behandlung einer biologischen Probe
US20090053704A1 (en) * 2007-08-24 2009-02-26 Natalia Novoradovskaya Stabilization of nucleic acids on solid supports
US7687027B2 (en) * 2008-02-27 2010-03-30 Becton, Dickinson And Company Cleaning compositions, methods and materials for reducing nucleic acid contamination
EP2411805A1 (en) 2009-03-27 2012-02-01 Université Libre de Bruxelles New marker for diagnosis of active multiple sclerosis
WO2011051402A1 (en) 2009-11-02 2011-05-05 Universite Libre De Bruxelles New biomarkers for determining allergy status
EP2345719A1 (en) 2010-01-18 2011-07-20 Qiagen GmbH Method for isolating small RNA
US8932809B2 (en) * 2010-01-19 2015-01-13 Opgen, Inc. Methods and kits for isolating nucleic acid from an organism
US20130095473A1 (en) 2010-06-14 2013-04-18 Qiagen Gmbh Method for determination of target cells or tissue for extraction of biomolecules from fixed biological samples
EP2407540A1 (en) 2010-07-15 2012-01-18 Qiagen GmbH Method for purifying a target nucleic acid
EP2598661B1 (en) 2010-07-26 2017-09-27 Biomatrica, INC. Compositions for stabilizing dna, rna and proteins in saliva and other biological samples during shipping and storage at ambient temperatures
US9376709B2 (en) 2010-07-26 2016-06-28 Biomatrica, Inc. Compositions for stabilizing DNA and RNA in blood and other biological samples during shipping and storage at ambient temperatures
CN102146422B (zh) * 2011-01-24 2013-08-07 南京工业大学 一种丁二酸的发酵生产工艺
US9476095B2 (en) 2011-04-15 2016-10-25 The Johns Hopkins University Safe sequencing system
EP2721140B1 (en) 2011-06-19 2016-11-23 Abogen, Inc. Devices, solutions and methods for sample collection
JP6096774B2 (ja) 2011-08-12 2017-03-15 キアゲン ゲゼルシャフト ミット ベシュレンクテル ハフツング 核酸を単離するための方法
AU2012314515B2 (en) 2011-09-26 2018-03-15 Preanalytix Gmbh Stabilisation and isolation of extracellular nucleic acids
US11021733B2 (en) 2011-09-26 2021-06-01 Qiagen Gmbh Stabilization and isolation of extracellular nucleic acids
WO2013119956A1 (en) 2012-02-09 2013-08-15 Life Technologies Corporation Conjugated polymeric particle and method of making same
EP2647709B1 (en) 2012-04-05 2016-02-24 F. Hoffmann-La Roche AG Amine compounds for the selective preparation of biological samples
WO2014029792A1 (en) 2012-08-21 2014-02-27 Qiagen Gmbh Virus particle stabilisation and method for isolating viral nucleic acids
US20150225712A1 (en) 2012-08-21 2015-08-13 Qiagen Gmbh Method for isolating nucleic acids from a formaldehyde releaser stabilized sample
JP6440616B2 (ja) * 2012-09-03 2018-12-19 キアゲン ゲーエムベーハー 高収量で小型rnaを含むrnaを単離するための方法
ES2614247T3 (es) 2012-09-25 2017-05-30 Qiagen Gmbh Estabilización de muestras biológicas
CN104956225B (zh) 2012-10-29 2018-10-02 约翰·霍普金斯大学 卵巢和子宫内膜癌的帕帕尼科拉乌测试
US9725703B2 (en) 2012-12-20 2017-08-08 Biomatrica, Inc. Formulations and methods for stabilizing PCR reagents
US10564150B2 (en) 2012-12-28 2020-02-18 Cellestis Limited Cell mediated immune response assay
GB201303666D0 (en) 2013-03-01 2013-04-17 Goldsborough Andrew S Sample fixation and stabilisation
CN105121643A (zh) 2013-03-18 2015-12-02 凯杰有限公司 细胞外核酸的稳定化和分离
EP2976424B1 (en) 2013-03-18 2018-10-03 Qiagen GmbH Stabilisation of biological samples
GB201305414D0 (en) 2013-03-25 2013-05-08 Arcis Biotechnology Holdings Ltd Method and composition
DK3114225T3 (da) 2014-03-07 2021-07-26 Dna Genotek Inc Sammensætning og fremgangsmåde til stabilisering af nukleinsyrer i biologiske prøver
JP6664332B2 (ja) 2014-03-18 2020-03-13 キアゲン ゲーエムベーハー 細胞外核酸の安定化および単離
JP6661554B2 (ja) 2014-06-10 2020-03-11 バイオマトリカ,インク. 周囲温度における血小板の安定化
EP3194563B1 (en) 2014-09-17 2023-05-10 Hologic, Inc. Method of partial lysis and assay
KR20180012266A (ko) 2015-05-27 2018-02-05 키아겐 게엠베하 조직 물질을 붕괴시키기 위한 조성물 및 방법
US10144968B2 (en) 2015-07-02 2018-12-04 Life Technologies Corporation Conjugation of carboxyl functional hydrophilic beads
US10150992B2 (en) 2015-07-06 2018-12-11 Life Technologies Corporation Substrates and methods useful in sequencing
US11286531B2 (en) 2015-08-11 2022-03-29 The Johns Hopkins University Assaying ovarian cyst fluid
CN108291250B (zh) 2015-11-20 2022-05-27 凯杰有限公司 用于稳定细胞外核酸的已灭菌组合物的制备方法
SG11201804776SA (en) 2015-12-08 2018-07-30 Biomatrica Inc Reduction of erythrocyte sedimentation rate
JP7274748B2 (ja) * 2016-11-08 2023-05-17 クヴェッラ コーポレーション 核酸の安定化及び分離を行う方法
EP3568475B1 (en) 2017-01-16 2023-03-08 Spectrum Solutions L.L.C. Nucleic acid preservation solution and methods of use
EP3665308A1 (en) 2017-08-07 2020-06-17 The Johns Hopkins University Methods and materials for assessing and treating cancer
CN110012899A (zh) * 2019-04-12 2019-07-16 南京科佰生物科技有限公司 细胞用rna稳定剂及其使用方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1289426A (hu) 1970-06-22 1972-09-20
US4900677A (en) * 1986-09-26 1990-02-13 E. I. Du Pont De Nemours And Company Process for rapid isolation of high molecular weight DNA
US5010183A (en) 1989-07-07 1991-04-23 Macfarlane Donald E Process for purifying DNA and RNA using cationic detergents
IT1240870B (it) 1990-02-14 1993-12-17 Talent Procedimento per l'estrazione e la purificazione di dna genomico umano
US5260048A (en) 1991-05-08 1993-11-09 Streck Laboratories, Inc. Tissue fixative solution and method
US5196182A (en) 1991-05-08 1993-03-23 Streck Laboratories, Inc. Tissue fixative
US5275708A (en) * 1992-03-20 1994-01-04 Thomas Jefferson University Cetyltrimethylammonium bromide gel electrophoresis
CA2107939C (en) * 1993-01-13 2001-01-30 Stephen B. Kong Acidic aqueous cleaning compositions
WO1994018156A1 (en) * 1993-02-01 1994-08-18 University Of Iowa Research Foundation Quartenary amine surfactants and methods of using same in isolation of rna
US5300635A (en) * 1993-02-01 1994-04-05 University Of Iowa Research Foundation Quaternary amine surfactants and methods of using same in isolation of nucleic acids
US5300645A (en) 1993-04-14 1994-04-05 Eli Lilly And Company Tetrahydro-pyrido-indole
US5641726A (en) 1993-06-09 1997-06-24 Lonza, Inc. Quaternary ammonium carboxylate and borate compositions and preparation thereof
ZA943999B (en) * 1993-06-09 1995-02-03 Lonza Ag Quaternary ammonium and waterproofing/preservative compositions
WO1995021849A1 (de) 1994-02-11 1995-08-17 Qiagen Gmbh Verfahren zur trennung von doppelstrang/einzelstrangnukleinsäurestrukturen
WO1999029904A2 (en) 1997-12-10 1999-06-17 Sierra Diagnostics, Inc. Methods and reagents for preservation of dna in bodily fluids
US6238888B1 (en) * 1997-12-22 2001-05-29 Human Genone Sciences, Inc. Keratinocyte growth factor-2 formulations
US6204375B1 (en) 1998-07-31 2001-03-20 Ambion, Inc. Methods and reagents for preserving RNA in cell and tissue samples
CA2299119C (en) 1999-02-23 2013-02-05 Qiagen Gmbh A method of stabilizing and/or isolating nucleic acids
DE10031236A1 (de) * 2000-06-27 2002-01-10 Qiagen Gmbh Verwendung von Carbonsäuren und anderen Additiven in Kombination mit kationischen Verbindungen zur Stabilisierung von Nukleinsäuren in biologischen Materialien

Also Published As

Publication number Publication date
US6861213B2 (en) 2005-03-01
JP5795455B2 (ja) 2015-10-14
AU783922B2 (en) 2005-12-22
CN1438988A (zh) 2003-08-27
SK18022002A3 (sk) 2003-07-01
CZ20024129A3 (cs) 2003-06-18
US20080071072A1 (en) 2008-03-20
US20040014703A1 (en) 2004-01-22
ATE524431T1 (de) 2011-09-15
US20030165943A1 (en) 2003-09-04
US7682790B2 (en) 2010-03-23
ATE394363T1 (de) 2008-05-15
AU7568501A (en) 2002-01-08
AU6903101A (en) 2002-01-08
WO2002000599A1 (de) 2002-01-03
CA2410388C (en) 2014-12-09
ES2295177T3 (es) 2008-04-16
JP2012135317A (ja) 2012-07-19
CN1250520C (zh) 2006-04-12
EP1820793B1 (de) 2011-09-14
AU2001269031B2 (en) 2007-01-11
MXPA02012261A (es) 2004-09-06
ES2373784T3 (es) 2012-02-08
DK1820793T3 (da) 2012-01-02
EP1296932A1 (de) 2003-04-02
EP1294676B1 (de) 2007-10-03
JP2004501621A (ja) 2004-01-22
CA2412534C (en) 2011-08-09
EP1294676A1 (de) 2003-03-26
PL360705A1 (en) 2004-09-20
DE50113941D1 (de) 2008-06-19
CA2412534A1 (en) 2002-12-17
DE50113086D1 (de) 2007-11-15
WO2002000600A1 (de) 2002-01-03
JP2004501622A (ja) 2004-01-22
ATE374743T1 (de) 2007-10-15
DK1294676T3 (da) 2008-02-04
EP1296932B1 (de) 2008-05-07
JP2015027310A (ja) 2015-02-12
DE10031236A1 (de) 2002-01-10
EP1820793A1 (de) 2007-08-22
AU2007201583A1 (en) 2007-05-03
JP5657847B2 (ja) 2015-01-21
CA2410388A1 (en) 2002-11-28
AU2007201583B2 (en) 2010-06-03
US7270953B2 (en) 2007-09-18
JP2015212273A (ja) 2015-11-26
BR0112002A (pt) 2003-05-13

Similar Documents

Publication Publication Date Title
HUP0301342A2 (hu) Kationos vegyületeket és protondonort tartalmazó készítmények alkalmazása nukleinsavak stabilizálására és/vagy izolálására mikroorganizmusokból, például prokariotákból, gombákból, protozoonokból vagy algákból
West Improvement of the selective respiratory inhibition technique to measure eukaryote: prokaryote ratios in soils
DE50015677D1 (de) Methode zur isolierung von dna aus biologischen materialien
AU2002235994A1 (en) Method for producing proteins by fermentation of microorganisms from the thermus family, the protein mixture thus obtained and cosmetic compositions containing same
MXPA02004415A (es) Pirazolonas sustituidas con heterociclicas.
AU2002359522A8 (en) Compositions and methods of selective nucleic acid isolation
AU2002348563A1 (en) Nucleic acid enrichment
WO2001057247A3 (de) Nukleinsäure-isolierung aus stuhlproben und anderen biologischen materialien, die reich an inhibitoren sind
AU636738B2 (en) Nematicidal compositions
AP1770A (en) HIV protease inhibitors, compositions containing the same, their pharmaceutical uses and materials for their sythesis.
DE60216447D1 (de) Vorrichtung und verfahren zur bearbeitung biologischer proben
HUP0100302A2 (hu) Eljárások a szerin/treonin protein-kináz funkció módositására 5-azakinoxalin-vázas vegyületekkel
DE69808274D1 (de) Kombinationsprodukt, enthaltend eine nukleinsäure und eine substanz, die die extrazellulärematrix desorganisiert, zur verwendung in gentherapie
AU2002359122A1 (en) Novel compounds
WO2002095055A8 (en) Compositions and methods for use in isolation of nucleic acid molecules
DE69821376D1 (de) Verfahren zur proteinrückfaltung durch verwendung zwitterionischer wirkstoffe von niedrigem molekulargewicht
DE60012820D1 (de) Zusammensetzungen zur Stabilisierung von sauerstoffempfindlichen Verbindungen
WO2001010894A3 (en) Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis
ATE247175T1 (de) Methode zur eliminierung von sequenzierartefakten
DE60129805D1 (de) Genetisches testverfahren zur bestimmung des risikos der entwicklung von pouchitis
PT1224455E (pt) Processo de separacao de um composto quimico ou biologico numa mistura de compostos similares por difusao num meio tal como um gel
WO2002100327A3 (en) Substituted 1-benzazepines and derivatives thereof
BR0012973B1 (pt) Uso de bactéria do ácido láctico pertencente ao gênero Bifidobacterium, e composição alimentícia ou farmacêutica.
UA84020C2 (ru) Ингибитор проникновения вируса вил
KR101646007B1 (ko) 리소좀 또는 리소좀 내 효소를 이용한 알데하이드계 악취 제거 조성물 및 악취 제거 방법

Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees