DK1175429T3 - Halogenderivater af 9-deoxo-9a-aza-9a-homoerythromycin A - Google Patents

Halogenderivater af 9-deoxo-9a-aza-9a-homoerythromycin A

Info

Publication number
DK1175429T3
DK1175429T3 DK00920940T DK00920940T DK1175429T3 DK 1175429 T3 DK1175429 T3 DK 1175429T3 DK 00920940 T DK00920940 T DK 00920940T DK 00920940 T DK00920940 T DK 00920940T DK 1175429 T3 DK1175429 T3 DK 1175429T3
Authority
DK
Denmark
Prior art keywords
meaning
homoerythromycin
deoxo
aza
halo
Prior art date
Application number
DK00920940T
Other languages
English (en)
Inventor
Stjepan Mutak
Zorica Marusic-Istuk
Nedjeljko Kujundzic
Gabrijela Kobrehel
Natasa Marsic
Original Assignee
Pliva Pharm & Chem Works
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva Pharm & Chem Works filed Critical Pliva Pharm & Chem Works
Application granted granted Critical
Publication of DK1175429T3 publication Critical patent/DK1175429T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK00920940T 1999-05-03 2000-05-02 Halogenderivater af 9-deoxo-9a-aza-9a-homoerythromycin A DK1175429T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HR990130A HRP990130B1 (en) 1999-05-03 1999-05-03 HALOGEN DERIVATIVES 9a-N-(N'-ARYLCARBAMOYL)- AND 9a-N-(N'-ARYLTHIOCARBAMOYL)-9-DEOXO-9a-AZA-9a OF HOMOERYTHROMYCIN A
PCT/HR2000/000013 WO2000066603A1 (en) 1999-05-03 2000-05-02 Halo derivatives of 9-deoxo-9a-aza-9a-homerythromycin a

Publications (1)

Publication Number Publication Date
DK1175429T3 true DK1175429T3 (da) 2003-10-20

Family

ID=10946916

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00920940T DK1175429T3 (da) 1999-05-03 2000-05-02 Halogenderivater af 9-deoxo-9a-aza-9a-homoerythromycin A

Country Status (33)

Country Link
US (1) US6872707B1 (da)
EP (1) EP1175429B1 (da)
JP (1) JP2002543213A (da)
KR (1) KR100714740B1 (da)
CN (1) CN1140535C (da)
AT (1) ATE244258T1 (da)
AU (1) AU767681B2 (da)
BG (1) BG106173A (da)
BR (1) BR0010231A (da)
CA (1) CA2372977A1 (da)
CZ (1) CZ20013913A3 (da)
DE (1) DE60003671T2 (da)
DK (1) DK1175429T3 (da)
EA (1) EA005214B1 (da)
EE (1) EE05007B1 (da)
ES (1) ES2202107T3 (da)
GE (1) GEP20032928B (da)
HK (1) HK1045522B (da)
HR (1) HRP990130B1 (da)
HU (1) HUP0201146A3 (da)
IL (2) IL145986A0 (da)
IS (1) IS6115A (da)
MX (1) MXPA01011038A (da)
NO (1) NO320138B1 (da)
NZ (1) NZ515278A (da)
PL (1) PL351402A1 (da)
PT (1) PT1175429E (da)
SI (1) SI1175429T1 (da)
SK (1) SK284513B6 (da)
TR (1) TR200103143T2 (da)
UA (1) UA71962C2 (da)
WO (1) WO2000066603A1 (da)
ZA (1) ZA200108484B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20010146B1 (en) * 2001-02-28 2005-10-31 Pliva D.D. 9a-N-(N'-(PHENYLSULFONYL)CARBAMOYL) DERIVATIVES OF 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERYTHROMYCIN A AND OF 5-O-DESOSAMINYL-9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERYTHRONOLIDE A
HRP20020886A2 (en) * 2002-11-11 2005-06-30 PLIVA-ISTRAŽIVAČKI INSTITUT d.o.o. SUBSTITUTED 9a-N-[N'-(BENZENSULFONYL)CARBAMOYL-γ-AMINOPROPYL) AND 9a-N(N' -(?-CYANOETHIL)-N' -(b
HRP20020885B1 (en) 2002-11-11 2007-05-31 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. SUBSTITUTED 9a-N-{N'-[4-(SULFONYL)PHENYLCARBAMOYL]}DERIVATIVES 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERITHROMYCIN A AND 5-O-DESOZAMINYL-9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERITHRONOLIDE A
HRP20020991A2 (en) * 2002-12-12 2005-02-28 Pliva-Istra�iva�ki institut d.o.o. N"-Substituted 9a-N-(N'-carbamoyl-Gamma-aminopropyl), 9a-N-(N'? -thiocarbamoyl-Gamma-aminopropyl), 9a-N-(N'-((Beta-cyanoethyl)-N'-carbamoyl-Gamma? -aminopropyl) and 9a-N-(N'-(Beta-cyanoethyl)-N'-thiocarbamoyl-Gamma? -aminopropyl) derivatives of 9-de
HRP20030381B1 (en) * 2003-05-14 2007-05-31 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. 3-DECLADINOZYL 9a-N-CARBAMOYL AND 9a-N-THIOCARBAMOYL DERIVATIVES 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERYTHROMICYNE A
US20080227730A1 (en) * 2005-01-14 2008-09-18 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. 9A-Carbamoyl and Thiocarbamoyl Azalides With Antimalarial Activity
WO2009075923A2 (en) * 2007-09-17 2009-06-18 Enanta Pharmaceuticals, Inc. 6, 11-bridged biaryl macrolides

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU43116B (en) * 1979-04-02 1989-04-30 Pliva Pharm & Chem Works Process for preparing 11-aza-4-o-cladinosyl-6-o-desosaminyl-15-ethyl-7,13,14-trihydroxy-3,5,7,9,12,14-hexamethyl-oxacyclopentadecane-2-one(11-aza-10-deox
CA2094060A1 (en) * 1990-10-15 1992-04-16 Toshifumi Asaka 2'-position modified compound of erythromycin or its derivative
HRP931480B1 (en) * 1993-12-08 1997-08-31 Sour Pliva 9a-N-(N'-CARBAMONYL) and 9a-N-(N'-THIOCARBAMONYL) DERIVATES OF 9-DEOXO-9a-HOMOERYTHROMYCIN A

Also Published As

Publication number Publication date
PL351402A1 (en) 2003-04-07
HRP990130A2 (en) 2001-10-31
TR200103143T2 (tr) 2002-04-22
BR0010231A (pt) 2002-02-19
SK15702001A3 (sk) 2002-04-04
EA005214B1 (ru) 2004-12-30
HUP0201146A3 (en) 2003-03-28
UA71962C2 (en) 2005-01-17
KR100714740B1 (ko) 2007-05-07
JP2002543213A (ja) 2002-12-17
SK284513B6 (sk) 2005-05-05
ATE244258T1 (de) 2003-07-15
CN1140535C (zh) 2004-03-03
HRP990130B1 (en) 2004-06-30
AU767681B2 (en) 2003-11-20
KR20020007397A (ko) 2002-01-26
MXPA01011038A (es) 2002-07-22
EP1175429A1 (en) 2002-01-30
EE05007B1 (et) 2008-04-15
GEP20032928B (en) 2003-03-25
IL145986A (en) 2006-10-31
IS6115A (is) 2001-10-19
EE200100582A (et) 2003-02-17
IL145986A0 (en) 2002-07-25
EA200101170A1 (ru) 2002-04-25
DE60003671T2 (de) 2004-06-17
ZA200108484B (en) 2003-03-26
DE60003671D1 (de) 2003-08-07
NO320138B1 (no) 2005-10-31
NO20015346D0 (no) 2001-11-01
CA2372977A1 (en) 2000-11-09
NO20015346L (no) 2001-11-01
NZ515278A (en) 2003-06-30
BG106173A (bg) 2002-07-31
CZ20013913A3 (cs) 2002-04-17
HK1045522B (zh) 2004-08-20
CN1351606A (zh) 2002-05-29
AU4135000A (en) 2000-11-17
PT1175429E (pt) 2003-11-28
WO2000066603A1 (en) 2000-11-09
SI1175429T1 (en) 2003-12-31
HK1045522A1 (en) 2002-11-29
EP1175429B1 (en) 2003-07-02
US6872707B1 (en) 2005-03-29
ES2202107T3 (es) 2004-04-01
HUP0201146A2 (hu) 2002-07-29

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