BR0006299A - Derivados da 4-oxo-2-ureìdo-1,4,5,6-tetra-hidro-pirimidina - Google Patents

Derivados da 4-oxo-2-ureìdo-1,4,5,6-tetra-hidro-pirimidina

Info

Publication number
BR0006299A
BR0006299A BR0006299-5A BR0006299A BR0006299A BR 0006299 A BR0006299 A BR 0006299A BR 0006299 A BR0006299 A BR 0006299A BR 0006299 A BR0006299 A BR 0006299A
Authority
BR
Brazil
Prior art keywords
oxo
pyrimidine
derivatives
tetrahydro
urea
Prior art date
Application number
BR0006299-5A
Other languages
English (en)
Inventor
Robert Gerald Ii Linde
Matthew Merrill Hayward
Takushi Kaneko
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of BR0006299A publication Critical patent/BR0006299A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/20—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D239/22—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Patente de Invenção: <B>"DERIVADOS DA 4-OXO-2-UREìDO-1,4,5,6-TETRA-HIDRO-PIRIMIDINA"<D>. A presente invenção refere-se a compostos de fórmula <B><MU>1<MV><D> e a sais farmaceuticamente aceitáveis, pró-drogas e solvatos daqueles, em que Z, R¹, R^ 9^ e R^ 10^ são como definidos aqui. A invenção também refere-se a composições farmacêuticas contendo os compostos acima e com métodos de tratar infecções bacterianas e infecções causadas por protozoários em mamíferos pela administração dos compostos acima.
BR0006299-5A 1999-12-29 2000-12-28 Derivados da 4-oxo-2-ureìdo-1,4,5,6-tetra-hidro-pirimidina BR0006299A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17343399P 1999-12-29 1999-12-29

Publications (1)

Publication Number Publication Date
BR0006299A true BR0006299A (pt) 2001-09-25

Family

ID=22631998

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0006299-5A BR0006299A (pt) 1999-12-29 2000-12-28 Derivados da 4-oxo-2-ureìdo-1,4,5,6-tetra-hidro-pirimidina

Country Status (4)

Country Link
US (2) US20020016297A1 (pt)
EP (1) EP1113008A1 (pt)
BR (1) BR0006299A (pt)
CA (1) CA2328775A1 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6555581B1 (en) 2001-02-15 2003-04-29 Jones Pharma, Inc. Levothyroxine compositions and methods
US8313760B2 (en) 2002-05-24 2012-11-20 Angiotech International Ag Compositions and methods for coating medical implants
CN100341589C (zh) 2002-05-24 2007-10-10 血管技术国际股份公司 用于涂覆医用植入物的组合物和方法
WO2005023368A1 (en) * 2003-09-04 2005-03-17 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Prophylaxis of and treatment for infections from the family chlamydiaceae using amino acids as leucine or methionine
MX2012004341A (es) 2009-10-16 2012-10-05 Rib X Pharmaceuticals Inc Compuestos antimicrobianos y metodos para fabricar y utilizar los mismos.
BR112012008795A2 (pt) 2009-10-16 2020-09-24 Rib-X Pharmaceuticals, Inc. compostos antimicrobianos e métodos de fabricação e uso dos mesmos.
DK2488525T3 (en) 2009-10-16 2018-08-06 Melinta Therapeutics Inc ANTIMICROBIAL COMPOUNDS AND PROCEDURES FOR PREPARING AND USING THEREOF
US9221827B2 (en) 2011-04-15 2015-12-29 Melinta Therapeutics, Inc. Antimicrobial compounds and methods of making and using the same
EP3039025A4 (en) 2013-09-09 2017-05-31 Melinta Therapeutics, Inc. Antimicrobial compounds and methods of making and using the same
CA2923179A1 (en) 2013-09-09 2015-03-12 Melinta Therapeutics, Inc. Antimicrobial compounds and methods of making and using the same
EA201792006A1 (ru) 2015-03-11 2018-04-30 Мелинта Терапьютикс, Инк. Антимикробные соединения и способы их получения и их применение

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2873340B2 (ja) * 1988-04-29 1999-03-24 武田薬品工業株式会社 抗生物質ｔａｎ―１０５７，その製造法および用途
EP1003727A1 (en) * 1997-08-07 2000-05-31 Research Corporation Technologies Antibiotic for methicillin resistant bacteria
DE19838998A1 (de) * 1998-08-27 2000-03-09 Bayer Ag Neue Naturstoffderivate

Also Published As

Publication number Publication date
EP1113008A1 (en) 2001-07-04
CA2328775A1 (en) 2001-06-29
US20020016297A1 (en) 2002-02-07
US20030055053A1 (en) 2003-03-20

Similar Documents

Publication Publication Date Title
BR9910900A (pt) Derivados isotiazol úteis como agentes anticancerìgenos
BR0010746A (pt) Derivados heterocìclicos úteis com agentes anticâncer
BR9913138A (pt) Derivados de quinolin-2-ona substituìdos com alquinila úteis como agentes contra o câncer
UY25679A1 (es) Derivados de quinolin-2-ona inhibidores de la farnesil proteína transferasa útiles como agentes contra el cáncer
BR9802851A (pt) Antibióticos de macrolìdeo substituìdos por c-4
BRPI9810519A (pt) derivados de 4&#39;&#39;-substituído-9-desoxo-9a-aza-9a-homoeritromicina a e composição farmacêutica compreendendo os mesmos.
BR0000003A (pt) Azalidas e métodos de preparação das mesmas
DK1265606T3 (da) Celleadhæsionsinhibitorer
BR9904998B1 (pt) derivados de hidroxamida do ácido 5-oxo-pirrolidina-2-carboxìlico e composição farmacêutica.
EA200100623A1 (ru) Кетолидные антибиотики
BR9810021A (pt) Derivados 9-oxima-eritromicina
BR0010938A (pt) Derivados da 13-metil eritromicina
BRPI0408338A (pt) piperidinas substituìdas como novos inibidores de mdm2-p53
BR9915480A (pt) Azalìdeos de 13 membros e a sua utilização como agentes antibióticos
BR9812148A (pt) Derivados de eritromicina 6,9-ligados em ponte
BR0006299A (pt) Derivados da 4-oxo-2-ureìdo-1,4,5,6-tetra-hidro-pirimidina
BR9905089A (pt) Derivados macrolìdeos
BR9910206A (pt) Derivados de higromicina a.
PT1175429E (pt) Derivados halo de 9-desoxo-9a-aza-9a-homoeritromicina a
BR0015153A (pt) Derivados de higromicina
BR9807506A (pt) Derivados de amida e composições medicinais dos mesmos
BR9915813A (pt) Derivados da higromicina a como agentes antibacterianos
DK0952157T3 (da) 9a, 11b-dehydroderivater af 9-oxim-3-keto-6-0-methylerythromycin
ECSP003744A (es) Derivados de higromicina
PT1144417E (pt) 4&#39;, 5&#39;-di-hidropsolarenos substituidos na posicao 4&#39; e suas utilizacoes terapeuticas

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 NA RPI2003 DE 26/05/2009.