PT1175429E - Derivados halo de 9-desoxo-9a-aza-9a-homoeritromicina a - Google Patents

Derivados halo de 9-desoxo-9a-aza-9a-homoeritromicina a

Info

Publication number
PT1175429E
PT1175429E PT00920940T PT00920940T PT1175429E PT 1175429 E PT1175429 E PT 1175429E PT 00920940 T PT00920940 T PT 00920940T PT 00920940 T PT00920940 T PT 00920940T PT 1175429 E PT1175429 E PT 1175429E
Authority
PT
Portugal
Prior art keywords
halo
meaning
deoxo
aza
derivatives
Prior art date
Application number
PT00920940T
Other languages
English (en)
Inventor
Nedeljko Kujundzic
Stjepen Mutak
Zorica Marusic-Istuk
Gabrijela Kobrehel
Natasa Marsic
Original Assignee
Pliva Pharm & Chem Works
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva Pharm & Chem Works filed Critical Pliva Pharm & Chem Works
Publication of PT1175429E publication Critical patent/PT1175429E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PT00920940T 1999-05-03 2000-05-02 Derivados halo de 9-desoxo-9a-aza-9a-homoeritromicina a PT1175429E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HR990130A HRP990130B1 (en) 1999-05-03 1999-05-03 HALOGEN DERIVATIVES 9a-N-(N'-ARYLCARBAMOYL)- AND 9a-N-(N'-ARYLTHIOCARBAMOYL)-9-DEOXO-9a-AZA-9a OF HOMOERYTHROMYCIN A

Publications (1)

Publication Number Publication Date
PT1175429E true PT1175429E (pt) 2003-11-28

Family

ID=10946916

Family Applications (1)

Application Number Title Priority Date Filing Date
PT00920940T PT1175429E (pt) 1999-05-03 2000-05-02 Derivados halo de 9-desoxo-9a-aza-9a-homoeritromicina a

Country Status (33)

Country Link
US (1) US6872707B1 (pt)
EP (1) EP1175429B1 (pt)
JP (1) JP2002543213A (pt)
KR (1) KR100714740B1 (pt)
CN (1) CN1140535C (pt)
AT (1) ATE244258T1 (pt)
AU (1) AU767681B2 (pt)
BG (1) BG106173A (pt)
BR (1) BR0010231A (pt)
CA (1) CA2372977A1 (pt)
CZ (1) CZ20013913A3 (pt)
DE (1) DE60003671T2 (pt)
DK (1) DK1175429T3 (pt)
EA (1) EA005214B1 (pt)
EE (1) EE05007B1 (pt)
ES (1) ES2202107T3 (pt)
GE (1) GEP20032928B (pt)
HK (1) HK1045522B (pt)
HR (1) HRP990130B1 (pt)
HU (1) HUP0201146A3 (pt)
IL (2) IL145986A0 (pt)
IS (1) IS6115A (pt)
MX (1) MXPA01011038A (pt)
NO (1) NO320138B1 (pt)
NZ (1) NZ515278A (pt)
PL (1) PL351402A1 (pt)
PT (1) PT1175429E (pt)
SI (1) SI1175429T1 (pt)
SK (1) SK284513B6 (pt)
TR (1) TR200103143T2 (pt)
UA (1) UA71962C2 (pt)
WO (1) WO2000066603A1 (pt)
ZA (1) ZA200108484B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20010146B1 (en) * 2001-02-28 2005-10-31 Pliva D.D. 9a-N-(N'-(PHENYLSULFONYL)CARBAMOYL) DERIVATIVES OF 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERYTHROMYCIN A AND OF 5-O-DESOSAMINYL-9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERYTHRONOLIDE A
HRP20020885B1 (en) 2002-11-11 2007-05-31 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. SUBSTITUTED 9a-N-{N'-[4-(SULFONYL)PHENYLCARBAMOYL]}DERIVATIVES 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERITHROMYCIN A AND 5-O-DESOZAMINYL-9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERITHRONOLIDE A
HRP20020886A2 (en) * 2002-11-11 2005-06-30 PLIVA-ISTRAŽIVAČKI INSTITUT d.o.o. SUBSTITUTED 9a-N-[N'-(BENZENSULFONYL)CARBAMOYL-γ-AMINOPROPYL) AND 9a-N(N' -(?-CYANOETHIL)-N' -(b
HRP20020991A2 (en) * 2002-12-12 2005-02-28 Pliva-Istra�iva�ki institut d.o.o. N"-Substituted 9a-N-(N'-carbamoyl-Gamma-aminopropyl), 9a-N-(N'? -thiocarbamoyl-Gamma-aminopropyl), 9a-N-(N'-((Beta-cyanoethyl)-N'-carbamoyl-Gamma? -aminopropyl) and 9a-N-(N'-(Beta-cyanoethyl)-N'-thiocarbamoyl-Gamma? -aminopropyl) derivatives of 9-de
HRP20030381B1 (en) * 2003-05-14 2007-05-31 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. 3-DECLADINOZYL 9a-N-CARBAMOYL AND 9a-N-THIOCARBAMOYL DERIVATIVES 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERYTHROMICYNE A
ATE429921T1 (de) * 2005-01-14 2009-05-15 Glaxosmithkline Zagreb 9a-carbamoyl- und thiocarbamoylazalide mit antimalariawirkung
JP5642548B2 (ja) * 2007-09-17 2014-12-17 エナンタ ファーマシューティカルズ インコーポレイテッド ６，１１−架橋ビアリールマクロライド

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU43116B (en) * 1979-04-02 1989-04-30 Pliva Pharm & Chem Works Process for preparing 11-aza-4-o-cladinosyl-6-o-desosaminyl-15-ethyl-7,13,14-trihydroxy-3,5,7,9,12,14-hexamethyl-oxacyclopentadecane-2-one(11-aza-10-deox
EP0553353A1 (en) * 1990-10-15 1993-08-04 Taisho Pharmaceutical Co. Ltd 2'-modified erythromycin or derivative thereof
HRP931480B1 (en) * 1993-12-08 1997-08-31 Sour Pliva 9a-N-(N'-CARBAMONYL) and 9a-N-(N'-THIOCARBAMONYL) DERIVATES OF 9-DEOXO-9a-HOMOERYTHROMYCIN A

Also Published As

Publication number Publication date
HRP990130A2 (en) 2001-10-31
DE60003671D1 (de) 2003-08-07
EE200100582A (et) 2003-02-17
HK1045522B (zh) 2004-08-20
JP2002543213A (ja) 2002-12-17
NZ515278A (en) 2003-06-30
NO320138B1 (no) 2005-10-31
TR200103143T2 (tr) 2002-04-22
IL145986A0 (en) 2002-07-25
DE60003671T2 (de) 2004-06-17
HRP990130B1 (en) 2004-06-30
AU767681B2 (en) 2003-11-20
CN1140535C (zh) 2004-03-03
ATE244258T1 (de) 2003-07-15
NO20015346L (no) 2001-11-01
EA005214B1 (ru) 2004-12-30
HUP0201146A2 (hu) 2002-07-29
DK1175429T3 (da) 2003-10-20
EA200101170A1 (ru) 2002-04-25
BG106173A (bg) 2002-07-31
HUP0201146A3 (en) 2003-03-28
ES2202107T3 (es) 2004-04-01
KR100714740B1 (ko) 2007-05-07
HK1045522A1 (en) 2002-11-29
UA71962C2 (en) 2005-01-17
ZA200108484B (en) 2003-03-26
WO2000066603A1 (en) 2000-11-09
PL351402A1 (en) 2003-04-07
IS6115A (is) 2001-10-19
EE05007B1 (et) 2008-04-15
GEP20032928B (en) 2003-03-25
IL145986A (en) 2006-10-31
CZ20013913A3 (cs) 2002-04-17
AU4135000A (en) 2000-11-17
CA2372977A1 (en) 2000-11-09
US6872707B1 (en) 2005-03-29
NO20015346D0 (no) 2001-11-01
EP1175429A1 (en) 2002-01-30
SK284513B6 (sk) 2005-05-05
MXPA01011038A (es) 2002-07-22
CN1351606A (zh) 2002-05-29
SK15702001A3 (sk) 2002-04-04
KR20020007397A (ko) 2002-01-26
EP1175429B1 (en) 2003-07-02
BR0010231A (pt) 2002-02-19
SI1175429T1 (en) 2003-12-31

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