EE200100582A - 9a-N-(N'-arüülkarbamoüül)- ja 9a-N-(N'-arüültiokarbamoüül)-9-desokso-9a-asa-9a-homoerütromütsiini Ahalogeenderivaadid, nende valmistamismeetod, farmatseutiline kompositsioon ja kasutamine - Google Patents

9a-N-(N'-arüülkarbamoüül)- ja 9a-N-(N'-arüültiokarbamoüül)-9-desokso-9a-asa-9a-homoerütromütsiini Ahalogeenderivaadid, nende valmistamismeetod, farmatseutiline kompositsioon ja kasutamine

Info

Publication number
EE200100582A
EE200100582A EEP200100582A EEP200100582A EE200100582A EE 200100582 A EE200100582 A EE 200100582A EE P200100582 A EEP200100582 A EE P200100582A EE P200100582 A EEP200100582 A EE P200100582A EE 200100582 A EE200100582 A EE 200100582A
Authority
EE
Estonia
Prior art keywords
preparation
meaning
arylthiocarbamoyl
homoerythromycin
deoxo
Prior art date
Application number
EEP200100582A
Other languages
English (en)
Inventor
Maru�ic- I�tuk Zorica
Kujundzic Nedjelko
Kobrehel Gabrijela
Mutak Stjepan
Mar�ic Nata�a
Original Assignee
PLIVA, farmaceutska industrija, dionicko dru�tvo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PLIVA, farmaceutska industrija, dionicko dru�tvo filed Critical PLIVA, farmaceutska industrija, dionicko dru�tvo
Publication of EE200100582A publication Critical patent/EE200100582A/et
Publication of EE05007B1 publication Critical patent/EE05007B1/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
EEP200100582A 1999-05-03 2000-05-02 9a-N-(N'-arlkarbamol)- ja 9a-N-(N'-arltiokarbamol)-9-desokso-9a-asa-9a-homoertromtsiini Ahalogeenderivaadid, nende valmistamismeetod, farmatseutiline kompositsioon ja kasutamine EE05007B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HR990130A HRP990130B1 (en) 1999-05-03 1999-05-03 HALOGEN DERIVATIVES 9a-N-(N'-ARYLCARBAMOYL)- AND 9a-N-(N'-ARYLTHIOCARBAMOYL)-9-DEOXO-9a-AZA-9a OF HOMOERYTHROMYCIN A
PCT/HR2000/000013 WO2000066603A1 (en) 1999-05-03 2000-05-02 Halo derivatives of 9-deoxo-9a-aza-9a-homerythromycin a

Publications (2)

Publication Number Publication Date
EE200100582A true EE200100582A (et) 2003-02-17
EE05007B1 EE05007B1 (et) 2008-04-15

Family

ID=10946916

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200100582A EE05007B1 (et) 1999-05-03 2000-05-02 9a-N-(N'-arlkarbamol)- ja 9a-N-(N'-arltiokarbamol)-9-desokso-9a-asa-9a-homoertromtsiini Ahalogeenderivaadid, nende valmistamismeetod, farmatseutiline kompositsioon ja kasutamine

Country Status (33)

Country Link
US (1) US6872707B1 (et)
EP (1) EP1175429B1 (et)
JP (1) JP2002543213A (et)
KR (1) KR100714740B1 (et)
CN (1) CN1140535C (et)
AT (1) ATE244258T1 (et)
AU (1) AU767681B2 (et)
BG (1) BG106173A (et)
BR (1) BR0010231A (et)
CA (1) CA2372977A1 (et)
CZ (1) CZ20013913A3 (et)
DE (1) DE60003671T2 (et)
DK (1) DK1175429T3 (et)
EA (1) EA005214B1 (et)
EE (1) EE05007B1 (et)
ES (1) ES2202107T3 (et)
GE (1) GEP20032928B (et)
HK (1) HK1045522B (et)
HR (1) HRP990130B1 (et)
HU (1) HUP0201146A3 (et)
IL (2) IL145986A0 (et)
IS (1) IS6115A (et)
MX (1) MXPA01011038A (et)
NO (1) NO320138B1 (et)
NZ (1) NZ515278A (et)
PL (1) PL351402A1 (et)
PT (1) PT1175429E (et)
SI (1) SI1175429T1 (et)
SK (1) SK284513B6 (et)
TR (1) TR200103143T2 (et)
UA (1) UA71962C2 (et)
WO (1) WO2000066603A1 (et)
ZA (1) ZA200108484B (et)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20010146B1 (en) * 2001-02-28 2005-10-31 Pliva D.D. 9a-N-(N'-(PHENYLSULFONYL)CARBAMOYL) DERIVATIVES OF 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERYTHROMYCIN A AND OF 5-O-DESOSAMINYL-9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERYTHRONOLIDE A
HRP20020885B1 (en) * 2002-11-11 2007-05-31 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. SUBSTITUTED 9a-N-{N'-[4-(SULFONYL)PHENYLCARBAMOYL]}DERIVATIVES 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERITHROMYCIN A AND 5-O-DESOZAMINYL-9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERITHRONOLIDE A
HRP20020886A2 (en) * 2002-11-11 2005-06-30 PLIVA-ISTRAŽIVAČKI INSTITUT d.o.o. SUBSTITUTED 9a-N-[N'-(BENZENSULFONYL)CARBAMOYL-γ-AMINOPROPYL) AND 9a-N(N' -(?-CYANOETHIL)-N' -(b
HRP20020991A2 (en) * 2002-12-12 2005-02-28 Pliva-Istra�iva�ki institut d.o.o. N"-Substituted 9a-N-(N'-carbamoyl-Gamma-aminopropyl), 9a-N-(N'? -thiocarbamoyl-Gamma-aminopropyl), 9a-N-(N'-((Beta-cyanoethyl)-N'-carbamoyl-Gamma? -aminopropyl) and 9a-N-(N'-(Beta-cyanoethyl)-N'-thiocarbamoyl-Gamma? -aminopropyl) derivatives of 9-de
HRP20030381B1 (en) * 2003-05-14 2007-05-31 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. 3-DECLADINOZYL 9a-N-CARBAMOYL AND 9a-N-THIOCARBAMOYL DERIVATIVES 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERYTHROMICYNE A
JP2008526948A (ja) * 2005-01-14 2008-07-24 グラクソスミスクライン・イストラジヴァッキ・センタル・ザグレブ・ドルズバ・ゼー・オメイェノ・オドゴヴォルノスティオ 抗マラリア活性を有する９ａ−カルバモイルおよびチオカルバモイルアザライド
WO2009039177A1 (en) * 2007-09-17 2009-03-26 Enanta Pharmaceuticals, Inc. 6, 11-bicycloides: bridged biaryl macrolide derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI7910768A8 (en) * 1979-04-02 1996-06-30 Pliva Pharm & Chem Works Process for pripering 11-aza-4-0-cladinosyl-6-0-desosaminyl-15-ethyl- 7,13,14-trihydroxy-3,5,7,9,12,14-hexamethyl- oxacyclopentadecane-2-one and their derivatives
KR930702369A (ko) * 1990-10-15 1993-09-08 우에노 아키라 에리쓰로마이신 또는 그의 유도체의 2'위치 수식 화합물
HRP931480B1 (en) * 1993-12-08 1997-08-31 Sour Pliva 9a-N-(N'-CARBAMONYL) and 9a-N-(N'-THIOCARBAMONYL) DERIVATES OF 9-DEOXO-9a-HOMOERYTHROMYCIN A

Also Published As

Publication number Publication date
ZA200108484B (en) 2003-03-26
NO320138B1 (no) 2005-10-31
SI1175429T1 (en) 2003-12-31
EA005214B1 (ru) 2004-12-30
PL351402A1 (en) 2003-04-07
PT1175429E (pt) 2003-11-28
HRP990130A2 (en) 2001-10-31
CN1140535C (zh) 2004-03-03
HK1045522B (zh) 2004-08-20
MXPA01011038A (es) 2002-07-22
IL145986A (en) 2006-10-31
DE60003671T2 (de) 2004-06-17
US6872707B1 (en) 2005-03-29
EE05007B1 (et) 2008-04-15
UA71962C2 (en) 2005-01-17
NO20015346L (no) 2001-11-01
EP1175429B1 (en) 2003-07-02
GEP20032928B (en) 2003-03-25
HUP0201146A2 (hu) 2002-07-29
HUP0201146A3 (en) 2003-03-28
CA2372977A1 (en) 2000-11-09
NO20015346D0 (no) 2001-11-01
BR0010231A (pt) 2002-02-19
KR20020007397A (ko) 2002-01-26
DK1175429T3 (da) 2003-10-20
HK1045522A1 (en) 2002-11-29
KR100714740B1 (ko) 2007-05-07
ATE244258T1 (de) 2003-07-15
SK15702001A3 (sk) 2002-04-04
SK284513B6 (sk) 2005-05-05
DE60003671D1 (de) 2003-08-07
IL145986A0 (en) 2002-07-25
EA200101170A1 (ru) 2002-04-25
JP2002543213A (ja) 2002-12-17
CZ20013913A3 (cs) 2002-04-17
TR200103143T2 (tr) 2002-04-22
ES2202107T3 (es) 2004-04-01
NZ515278A (en) 2003-06-30
CN1351606A (zh) 2002-05-29
WO2000066603A1 (en) 2000-11-09
AU4135000A (en) 2000-11-17
IS6115A (is) 2001-10-19
HRP990130B1 (en) 2004-06-30
EP1175429A1 (en) 2002-01-30
AU767681B2 (en) 2003-11-20
BG106173A (bg) 2002-07-31

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Legal Events

Date Code Title Description
GB1A Change in the ownership or in the address of the owner
GB1A Change in the ownership or in the address of the owner
KB4A Valid patent at the end of a year

Effective date: 20081231

MM4A Lapsed by not paying the annual fees

Effective date: 20090502