BR9905089A - Derivados macrolìdeos - Google Patents

Derivados macrolìdeos

Info

Publication number
BR9905089A
BR9905089A BR9905089-7A BR9905089A BR9905089A BR 9905089 A BR9905089 A BR 9905089A BR 9905089 A BR9905089 A BR 9905089A BR 9905089 A BR9905089 A BR 9905089A
Authority
BR
Brazil
Prior art keywords
compounds
formula
macrolide derivatives
derivatives
macrolydic
Prior art date
Application number
BR9905089-7A
Other languages
English (en)
Inventor
Brian Scott Bronk
Hengmiao Cheng
Jason Kenneth Dutra
Michael Anthony Letavic
Robert John Rafka
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of BR9905089A publication Critical patent/BR9905089A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Patente de Invenção: <B>"DERIVADOS MACROLìDEOS"<D>. A invenção refere-se a compostos da fórmula I e aos seus sais farmaceuticamente aceitáveis, em que R^ 1^, R^ 2^, R^ 3^, Q, X, Y, e Z têm o significado atribuído no texto. A invenção também abarca composições farmacêuticas contendo os compostos da fórmula I, os métodos de utilização dos referidos compostos da fórmula I para tratamento de infecções, e os processos de síntese dos referidos compostos da fórmula I.
BR9905089-7A 1998-10-09 1999-10-11 Derivados macrolìdeos BR9905089A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10383898P 1998-10-09 1998-10-09

Publications (1)

Publication Number Publication Date
BR9905089A true BR9905089A (pt) 2000-08-08

Family

ID=22297279

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9905089-7A BR9905089A (pt) 1998-10-09 1999-10-11 Derivados macrolìdeos

Country Status (10)

Country Link
US (1) US6100240A (pt)
EP (1) EP0992509B1 (pt)
JP (1) JP3679656B2 (pt)
AT (1) ATE277062T1 (pt)
BR (1) BR9905089A (pt)
CA (1) CA2286511C (pt)
DE (1) DE69920362T2 (pt)
DK (1) DK0992509T3 (pt)
ES (1) ES2226294T3 (pt)
PT (1) PT992509E (pt)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ502861A (en) * 1997-09-10 2001-03-30 Merck & Co Inc Method of treating livestock bacterial respiratory or enteric infections using 9a-azalides
EP1779853A3 (en) * 1997-09-10 2010-01-27 Merial Ltd. 9a-azalides as veterinary antimicrobial agents
US6339063B1 (en) 1997-09-10 2002-01-15 Merck & Co., Inc. 9a-azalides as veterinary antimicrobial agents
AP1060A (en) * 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
AP9801420A0 (en) * 1998-01-02 1998-12-31 Pfizer Prod Inc Novel macrolides.
ID30233A (id) * 1999-01-27 2001-11-15 Pfizer Prod Inc Antibiotika ketolida
CA2411293A1 (en) * 1999-01-28 2000-07-28 Pfizer Products Inc. Novel azalides and methods of making same
US6939861B2 (en) 1999-04-16 2005-09-06 Kosan Biosciences, Inc. Amido macrolides
PL352720A1 (en) * 1999-05-24 2003-09-08 Pfizer Products Inc. 13-methyl-erythromycin derivatives
US6420535B1 (en) * 1999-06-07 2002-07-16 Abbott Laboratories 6-O-carbamate ketolide derivatives
AP2002002652A0 (en) * 2000-04-27 2002-12-31 Pfizer Prod Inc The use of azalide antibiotic composition for treating or preventing a bacterial or protozoal infection in mammals.
EP1471923A4 (en) * 2002-01-17 2006-01-11 Kosan Biosciences Inc AMIDO macrolides
US7579324B2 (en) 2002-02-15 2009-08-25 C-A-I-R Biosciences Gmbh Conjugates of biologically active compounds, methods for their preparation and use, formulation and pharmaceutical applications thereof
US20040005641A1 (en) 2002-02-15 2004-01-08 Michael Burnet Conjugates of biologically active compounds, methods for their preparation and use, formulation and pharmaceutical applications thereof
WO2003070254A1 (en) 2002-02-15 2003-08-28 Sympore Gmbh Antibiotic conjugates
CN101423539B (zh) * 2008-12-09 2011-04-27 山东大学 4″,11-二氨基甲酸酯阿奇霉素衍生物、制备方法及其药物组合物
CN105669798B (zh) * 2013-08-23 2019-07-26 普莱柯生物工程股份有限公司 一种大环内酯类化合物
CN103965273B (zh) 2013-08-23 2016-05-25 普莱柯生物工程股份有限公司 一种大环内酯类化合物
CN109535211B (zh) * 2018-12-19 2020-05-08 江苏威凌生化科技有限公司 一种合成纯化泰拉霉素杂质c的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5441939A (en) * 1994-03-04 1995-08-15 Pfizer Inc. 3"-desmethoxy derivatives of erythromycin and azithromycin
US5641753A (en) * 1996-03-25 1997-06-24 Chris E. Platt 10-AZA-9-deoxo-11-deoxy-erythromycin A and derivatives combined with sulfisoxazole
HN1998000086A (es) * 1997-06-11 1999-03-08 Pfizer Prod Inc Derivados de 9 - desofo - 9 aza - 9a - homoeritromicina a - c - 4 sustituidos.
HN1998000074A (es) * 1997-06-11 1999-01-08 Pfizer Prod Inc Derivados de macrolidos c-4 sustituidos

Also Published As

Publication number Publication date
JP2000119294A (ja) 2000-04-25
CA2286511C (en) 2003-07-08
EP0992509A2 (en) 2000-04-12
EP0992509A3 (en) 2001-03-07
DE69920362D1 (de) 2004-10-28
US6100240A (en) 2000-08-08
JP3679656B2 (ja) 2005-08-03
CA2286511A1 (en) 2000-04-09
PT992509E (pt) 2004-12-31
EP0992509B1 (en) 2004-09-22
ES2226294T3 (es) 2005-03-16
DE69920362T2 (de) 2006-02-09
ATE277062T1 (de) 2004-10-15
DK0992509T3 (da) 2004-12-20

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PRESENTE PEDIDO DE PATENTE DE ACORDO COM ART. 8O DA LPI.

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.