BR9814601A - "macrólidos" - Google Patents

"macrólidos"

Info

Publication number
BR9814601A
BR9814601A BR9814601-7A BR9814601A BR9814601A BR 9814601 A BR9814601 A BR 9814601A BR 9814601 A BR9814601 A BR 9814601A BR 9814601 A BR9814601 A BR 9814601A
Authority
BR
Brazil
Prior art keywords
compounds
preparation
methods
relates
new
Prior art date
Application number
BR9814601-7A
Other languages
English (en)
Inventor
John Philip Dirlam
Hamish Alastair Irvin Mcarthur
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of BR9814601A publication Critical patent/BR9814601A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Abstract

Patente de Invenção: <B>"MACRóLIDOS"<D>. A invenção refere-se a novos análogos de eritromicina e azalidas, particularmente os possuidores de novos substituintes de C-13, e com seus sais farmaceuticamente aceitáveis. Os compostos desta invenção são agentes antibacterianos que podem ser usados para tratar várias infecções bacterianas e por protozoários. A invenção também está relacionada com composições farmacêuticas contendo tais compostos e com métodos para o tratamento de infecções por bactérias e protozoários através da administração de tais compostos. A invenção está também relacionada com métodos para a preparação de tais compostos e com intermediários úteis nessa preparação.
BR9814601-7A 1998-01-02 1998-12-21 "macrólidos" BR9814601A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7034398P 1998-01-02 1998-01-02
PCT/IB1998/002099 WO1999035156A1 (en) 1998-01-02 1998-12-21 Novel macrolides

Publications (1)

Publication Number Publication Date
BR9814601A true BR9814601A (pt) 2000-10-17

Family

ID=22094723

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9814601-7A BR9814601A (pt) 1998-01-02 1998-12-21 "macrólidos"

Country Status (34)

Country Link
US (2) US6472371B1 (pt)
EP (1) EP1044207A1 (pt)
JP (1) JP2002500230A (pt)
KR (1) KR100352809B1 (pt)
CN (1) CN1284081A (pt)
AP (1) AP9801420A0 (pt)
AR (4) AR014948A1 (pt)
AU (1) AU756409B2 (pt)
BG (1) BG104644A (pt)
BR (1) BR9814601A (pt)
CA (1) CA2316919C (pt)
CO (1) CO4970821A1 (pt)
CZ (1) CZ20002458A3 (pt)
DZ (1) DZ2698A1 (pt)
EA (1) EA200000594A1 (pt)
GT (1) GT199800206A (pt)
HR (1) HRP20000442A2 (pt)
HU (1) HUP0100420A3 (pt)
IL (1) IL137024A0 (pt)
IS (1) IS5528A (pt)
MA (1) MA24729A1 (pt)
NO (1) NO20003347L (pt)
NZ (1) NZ504986A (pt)
OA (1) OA11438A (pt)
PA (1) PA8465301A1 (pt)
PE (1) PE20000049A1 (pt)
PL (1) PL341642A1 (pt)
SK (1) SK9782000A3 (pt)
TN (1) TNSN98238A1 (pt)
TW (1) TW520374B (pt)
UY (2) UY25330A1 (pt)
WO (1) WO1999035156A1 (pt)
YU (1) YU41500A (pt)
ZA (1) ZA9811939B (pt)

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AP9801420A0 (en) 1998-01-02 1998-12-31 Pfizer Prod Inc Novel macrolides.
AP1060A (en) 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
EP1437360A3 (en) * 1998-08-19 2005-04-06 Pfizer Products Inc. C11 Carbamates of macrolide antibacterials
US6043227A (en) * 1998-08-19 2000-03-28 Pfizer Inc. C11 carbamates of macrolide antibacterials
EP1754700A3 (en) 1999-01-27 2007-05-09 Kosan Biosciences, Inc. Synthesis of oligoketides
IL145976A0 (en) 1999-04-16 2002-07-25 Ortho Mcneil Pharm Inc Ketolide antibacterials
US6451768B1 (en) 1999-04-16 2002-09-17 Kosan Biosciences, Inc. Macrolide antiinfective agents
US6590083B1 (en) 1999-04-16 2003-07-08 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
WO2000071557A1 (en) 1999-05-24 2000-11-30 Pfizer Products Inc. 13-methyl-erythromycin derivatives
WO2003072589A1 (fr) * 2002-02-26 2003-09-04 Meiji Seika Kaisha, Ltd. Nouveau compose azalide cyclique a 15 chainons, nouveau derive diazalide cyclique a 16 chainons et procede de production de ceux-ci
AR054981A1 (es) 2004-09-23 2007-08-01 Schering Plough Ltd Control de parasitos en animales mediante el uso de nuevos derivados de trifluorometansulfonanilida oxima eter
JP4750126B2 (ja) * 2004-11-19 2011-08-17 シェーリング−プラウ・リミテッド 殺寄生虫薬２−フェニル−３−（１ｈ−ピロール−２−イル）アクリロニトリル誘導体の使用による動物における寄生虫の制御
UA85937C2 (uk) * 2004-12-21 2009-03-10 Пфайзер Продактс Інк. Макроліди
JP2008545788A (ja) * 2005-06-09 2008-12-18 シェーリング−プラウ・リミテッド Ｎ−［（フェニルオキシ）フェニル］−１，１，１−トリフルオロメタンスルホンアミドおよびｎ−［（フェニルスルファニル）フェニル）］−１，１，１−トリフルオロメタンスルホンアミド誘導体による動物中の寄生生物の制御
US8119667B2 (en) * 2005-12-29 2012-02-21 Schering-Plough Animal Health Corporation Carbonates of fenicol antibiotics
US20070238700A1 (en) * 2006-04-10 2007-10-11 Winzenberg Kevin N N-phenyl-1,1,1-trifluoromethanesulfonamide hydrazone derivative compounds and their usage in controlling parasites
EP2102154A1 (en) * 2006-12-13 2009-09-23 Schering-Plough Ltd. Water-soluble prodrugs of chloramphenicol, thiamphenicol, and analogs thereof
MX2009006282A (es) * 2006-12-13 2009-06-23 Schering Plough Ltd Profarmacos solubles en agua de florfenicol y sus analogos.
TWI430995B (zh) 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
DK2957284T3 (en) 2007-06-27 2018-02-05 Du Pont PROCEDURE TO CHECK ANIMALS FOR ANIMALS
WO2009064953A1 (en) * 2007-11-15 2009-05-22 Enanta Pharmaceuticals, Inc. Use of bridged macrolides or tylosin derivatives in treating inflammatory bowel diseases
TWI401023B (zh) 2008-02-06 2013-07-11 Du Pont 中離子農藥
KR20110038723A (ko) * 2008-07-30 2011-04-14 인터벳 인터내셔널 비.브이. 플로르페니콜에 대한 중간체로서 유용한 옥사졸린-보호된 아미노디올 화합물의 제조 방법
UA110924C2 (uk) 2009-08-05 2016-03-10 Е. І. Дю Пон Де Немур Енд Компані Мезоіонні пестициди
KR20120047996A (ko) 2009-08-05 2012-05-14 이 아이 듀폰 디 네모아 앤드 캄파니 메소이온성 살충제
UA107804C2 (en) 2009-08-05 2015-02-25 Du Pont Mixtures of pesticides mezoionnyh
AU2010279574A1 (en) 2009-08-05 2012-02-09 E. I. Du Pont De Nemours And Company Mesoionic pesticides
MA34247B1 (fr) 2010-05-27 2013-05-02 Du Pont Forme cristalline du 4-[5-[3-chloro-5-(trifluorométhyl) phényl] -4,5-dihydro-5-(trifluorométhyl)-3-isoxazolyl]-n-[2-oxo-2-[(2, 2,2-trifluoroéthyl) amino] éthyl]-1-naphtalènecarboxamide
WO2012087630A1 (en) 2010-12-20 2012-06-28 E.I. Du Pont De Nemours And Company Pyridine and pyrimidine compounds for controlling invertebrate
EP2671887A4 (en) * 2011-01-31 2014-06-25 Meiji Seika Pharma Co Ltd NEW MACROLIDE DERIVATIVE
BR112013032813A2 (pt) 2011-06-20 2016-08-16 Du Pont composto de fórmula, composição e método para o tratamento, controle, prevenção ou proteção dos animais contra a infecção por helmintos
CN102260306B (zh) * 2011-07-22 2012-07-18 山东鲁抗舍里乐药业有限公司 一种制备泰拉霉素的方法
RU2014126367A (ru) 2011-11-28 2016-01-27 Е.И.Дюпон Де Немур Энд Компани Производные n-(4-хинолинметил)сульфонамидов и их применение в качестве антигельминтных средств
WO2013158422A1 (en) 2012-04-17 2013-10-24 E. I. Du Pont De Nemours And Company Heterocyclic compounds for controlling invertebrate pests
WO2014099837A1 (en) 2012-12-18 2014-06-26 E. I. Du Pont De Nemours And Company Sulfonamide anthelmintics
CN103965273B (zh) * 2013-08-23 2016-05-25 普莱柯生物工程股份有限公司 一种大环内酯类化合物
CN105669798B (zh) * 2013-08-23 2019-07-26 普莱柯生物工程股份有限公司 一种大环内酯类化合物

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Also Published As

Publication number Publication date
JP2002500230A (ja) 2002-01-08
BG104644A (en) 2001-01-31
GT199800206A (es) 2000-06-21
AU756409B2 (en) 2003-01-09
MA24729A1 (fr) 1999-07-01
TW520374B (en) 2003-02-11
HUP0100420A2 (hu) 2001-07-30
AR020851A2 (es) 2002-05-29
OA11438A (en) 2004-04-30
KR20010024818A (ko) 2001-03-26
PE20000049A1 (es) 2000-02-07
YU41500A (sh) 2003-02-28
WO1999035156A1 (en) 1999-07-15
AU1444799A (en) 1999-07-26
TNSN98238A1 (fr) 2005-03-15
CO4970821A1 (es) 2000-11-07
UY25574A1 (es) 1999-09-27
WO1999035156B1 (en) 1999-10-21
US20040092459A1 (en) 2004-05-13
SK9782000A3 (en) 2001-12-03
AR014948A1 (es) 2001-04-11
NO20003347L (no) 2000-08-28
EA200000594A1 (ru) 2001-04-23
HUP0100420A3 (en) 2003-07-28
NZ504986A (en) 2003-03-28
PL341642A1 (en) 2001-04-23
IS5528A (is) 2000-06-09
US6472371B1 (en) 2002-10-29
CZ20002458A3 (cs) 2001-10-17
ZA9811939B (en) 2000-06-30
HRP20000442A2 (en) 2001-04-30
IL137024A0 (en) 2001-06-14
US7015203B2 (en) 2006-03-21
AR019787A2 (es) 2002-03-13
CN1284081A (zh) 2001-02-14
EP1044207A1 (en) 2000-10-18
CA2316919A1 (en) 1999-07-15
AP9801420A0 (en) 1998-12-31
UY25330A1 (es) 2000-12-29
KR100352809B1 (ko) 2002-11-01
NO20003347D0 (no) 2000-06-27
DZ2698A1 (fr) 2003-03-29
AR020551A2 (es) 2002-05-15
PA8465301A1 (es) 2000-09-29
CA2316919C (en) 2004-10-26

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Legal Events

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 9A E 10A ANUIDADES

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 1994 DE 24/03/2009