DK10697A - (-)-(3R)-3-methyl-4-(4-(4-(4-pyridyl)Piperazinl-yl)phenoxy)smørsyre som cellulær adhæsionsinhibitor. - Google Patents

(-)-(3R)-3-methyl-4-(4-(4-(4-pyridyl)Piperazinl-yl)phenoxy)smørsyre som cellulær adhæsionsinhibitor. Download PDF

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Publication number
DK10697A
DK10697A DK010697A DK10697A DK10697A DK 10697 A DK10697 A DK 10697A DK 010697 A DK010697 A DK 010697A DK 10697 A DK10697 A DK 10697A DK 10697 A DK10697 A DK 10697A
Authority
DK
Denmark
Prior art keywords
piperazinl
phenoxy
pyridyl
methyl
butyric acid
Prior art date
Application number
DK010697A
Other languages
Danish (da)
English (en)
Inventor
Stuart Dennett Mills
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/457,538 external-priority patent/US5652242A/en
Priority claimed from GBGB9518188.9A external-priority patent/GB9518188D0/en
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Publication of DK10697A publication Critical patent/DK10697A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK010697A 1995-06-01 1997-01-30 (-)-(3R)-3-methyl-4-(4-(4-(4-pyridyl)Piperazinl-yl)phenoxy)smørsyre som cellulær adhæsionsinhibitor. DK10697A (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/457,538 US5652242A (en) 1993-03-29 1995-06-01 Heterocyclic derivatives
GBGB9518188.9A GB9518188D0 (en) 1995-09-07 1995-09-07 Optically active derivative
PCT/GB1996/001260 WO1996038416A1 (en) 1995-06-01 1996-05-28 (-)-(3r)-3-methyl-4-{4-[4-(4-pyridyl)piperazin-1-yl]phenoxy} butyric acid as cellular adhesion inhibitor

Publications (1)

Publication Number Publication Date
DK10697A true DK10697A (da) 1997-04-01

Family

ID=26307696

Family Applications (1)

Application Number Title Priority Date Filing Date
DK010697A DK10697A (da) 1995-06-01 1997-01-30 (-)-(3R)-3-methyl-4-(4-(4-(4-pyridyl)Piperazinl-yl)phenoxy)smørsyre som cellulær adhæsionsinhibitor.

Country Status (31)

Country Link
EP (1) EP0796247A1 (no)
JP (1) JP2885941B2 (no)
KR (1) KR100245957B1 (no)
AT (1) AT406675B (no)
AU (1) AU710105B2 (no)
BE (1) BE1009520A5 (no)
BR (1) BR9606409A (no)
CA (1) CA2194397A1 (no)
CH (1) CH691808A5 (no)
CZ (1) CZ26997A3 (no)
DE (1) DE19680509T1 (no)
DK (1) DK10697A (no)
ES (1) ES2137886B1 (no)
FI (1) FI970393A0 (no)
GB (1) GB2304340B (no)
GR (1) GR1002702B (no)
HU (1) HUP9700274A3 (no)
IE (1) IE960405A1 (no)
IL (1) IL118477A0 (no)
IT (1) IT1290839B1 (no)
LU (1) LU90008B1 (no)
MC (1) MC2418A1 (no)
MX (1) MX9700379A (no)
NL (1) NL1003243C2 (no)
NO (1) NO307460B1 (no)
NZ (1) NZ308597A (no)
PL (1) PL318440A1 (no)
SE (1) SE510812C2 (no)
SK (1) SK13097A3 (no)
TR (1) TR199700020T1 (no)
WO (1) WO1996038416A1 (no)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0100158A3 (en) * 1982-07-28 1985-03-27 The Upjohn Company (3-pyridinyl)heteroalkarylalkanols, alkanoic acids and esters
GB8609630D0 (en) * 1986-04-19 1986-05-21 Pfizer Ltd Anti-arrhythmia agents
PL310889A1 (en) * 1993-03-29 1996-01-08 Zeneca Ltd Heterocyclic derivatives as inhibitors of thrombocytes aggregation
NZ262942A (en) * 1993-03-29 1997-07-27 Zeneca Ltd Pyridyl substituted piperazine and various other derivatives of azaheteroaryl substituted piperazines; pharmaceutical compositions

Also Published As

Publication number Publication date
IL118477A0 (en) 1996-09-12
AT406675B (de) 2000-07-25
FI970393A (fi) 1997-01-30
ATA900596A (de) 1999-12-15
ES2137886A1 (es) 1999-12-16
HU9700274D0 (en) 1997-04-28
JP2885941B2 (ja) 1999-04-26
DE19680509T1 (de) 1997-12-04
KR970704689A (ko) 1997-09-06
SK13097A3 (en) 1997-08-06
ES2137886B1 (es) 2000-08-16
TR199700020T1 (tr) 1997-04-22
ITMI961113A0 (it) 1996-05-31
FI970393A0 (fi) 1997-01-30
LU90008B1 (fr) 1997-04-16
NO970437D0 (no) 1997-01-31
PL318440A1 (en) 1997-06-09
CA2194397A1 (en) 1996-12-05
NL1003243C2 (nl) 1996-12-04
ITMI961113A1 (it) 1997-12-01
CH691808A5 (de) 2001-10-31
SE9700203L (sv) 1997-01-24
MX9700379A (es) 1997-04-30
HUP9700274A3 (en) 2000-02-28
CZ26997A3 (en) 1997-08-13
KR100245957B1 (ko) 2000-04-01
HUP9700274A2 (hu) 1999-06-28
AU5827296A (en) 1996-12-18
GB9627127D0 (en) 1997-02-19
SE510812C2 (sv) 1999-06-28
BR9606409A (pt) 1997-09-30
IT1290839B1 (it) 1998-12-14
JPH09512836A (ja) 1997-12-22
MC2418A1 (fr) 1997-05-23
NO970437L (no) 1997-02-20
SE9700203D0 (sv) 1997-01-24
WO1996038416A1 (en) 1996-12-05
GR1002702B (el) 1997-05-22
NZ308597A (en) 1998-11-25
IE960405A1 (en) 1996-12-11
EP0796247A1 (en) 1997-09-24
NO307460B1 (no) 2000-04-10
GB2304340A (en) 1997-03-19
AU710105B2 (en) 1999-09-16
GB2304340B (en) 1998-07-29
BE1009520A5 (fr) 1997-04-01

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment