DK1042324T3 - Heterocykliske forbindelser til inhibering af mavesyresekretion, fremgangsmåder til deres fremstilling og farmaceutiske præparater deraf - Google Patents

Heterocykliske forbindelser til inhibering af mavesyresekretion, fremgangsmåder til deres fremstilling og farmaceutiske præparater deraf

Info

Publication number
DK1042324T3
DK1042324T3 DK98957270T DK98957270T DK1042324T3 DK 1042324 T3 DK1042324 T3 DK 1042324T3 DK 98957270 T DK98957270 T DK 98957270T DK 98957270 T DK98957270 T DK 98957270T DK 1042324 T3 DK1042324 T3 DK 1042324T3
Authority
DK
Denmark
Prior art keywords
inhibition
preparation
methods
pharmaceutical preparations
heterocyclic compounds
Prior art date
Application number
DK98957270T
Other languages
Danish (da)
English (en)
Inventor
Kosrat Amin
Mikael Dahlstroem
Peter Nordberg
Ingemar Starke
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of DK1042324T3 publication Critical patent/DK1042324T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK98957270T 1997-11-28 1998-11-18 Heterocykliske forbindelser til inhibering af mavesyresekretion, fremgangsmåder til deres fremstilling og farmaceutiske præparater deraf DK1042324T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9704404A SE9704404D0 (sv) 1997-11-28 1997-11-28 New compounds
PCT/SE1998/002091 WO1999028322A1 (en) 1997-11-28 1998-11-18 Heterocyclic compounds for inhibition of gastric acid secretion, processes for their preparation and pharmaceutical compositions thereof

Publications (1)

Publication Number Publication Date
DK1042324T3 true DK1042324T3 (da) 2003-05-05

Family

ID=20409181

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98957270T DK1042324T3 (da) 1997-11-28 1998-11-18 Heterocykliske forbindelser til inhibering af mavesyresekretion, fremgangsmåder til deres fremstilling og farmaceutiske præparater deraf

Country Status (32)

Country Link
US (1) US6518270B1 (https=)
EP (1) EP1042324B1 (https=)
JP (1) JP2001525322A (https=)
KR (1) KR20010032559A (https=)
CN (1) CN1142933C (https=)
AR (1) AR016972A1 (https=)
AT (1) ATE233263T1 (https=)
AU (1) AU752187C (https=)
BR (1) BR9814755A (https=)
CA (1) CA2311798A1 (https=)
CZ (1) CZ292349B6 (https=)
DE (1) DE69811735T2 (https=)
DK (1) DK1042324T3 (https=)
EE (1) EE04060B1 (https=)
ES (1) ES2191356T3 (https=)
HU (1) HUP0100601A3 (https=)
ID (1) ID24730A (https=)
IL (1) IL136145A0 (https=)
IS (1) IS5486A (https=)
MY (1) MY121032A (https=)
NO (1) NO315704B1 (https=)
NZ (1) NZ504355A (https=)
PL (1) PL340920A1 (https=)
PT (1) PT1042324E (https=)
RU (1) RU2241000C2 (https=)
SE (1) SE9704404D0 (https=)
SK (1) SK283904B6 (https=)
TR (1) TR200001530T2 (https=)
TW (1) TW515798B (https=)
UA (1) UA70932C2 (https=)
WO (1) WO1999028322A1 (https=)
ZA (1) ZA9810468B (https=)

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MX2007002214A (es) 2004-09-03 2007-05-07 Yuhan Corp Derivados de pirrolo[3,2-c]piridina y procesos para su preparacion.
ATE466013T1 (de) * 2004-09-03 2010-05-15 Yuhan Corp Pyrroloä3,2-cüpyridinderivate und verfahren zu deren herstellung
WO2007024294A2 (en) 2005-05-03 2007-03-01 Cgi Pharmaceuticals, Inc. Certain substituted ureas, as modulators of kinase activity
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EP1973902A2 (en) * 2005-12-05 2008-10-01 Affinium Pharmaceuticals, Inc. 3-heterocyclylacrylamide compounds as fabi inhibitors and antibacterial agents
AR061229A1 (es) * 2006-06-06 2008-08-13 Schering Corp Imidazopirazinas como inhibidores de la proteina quinasa
EP2687533B1 (en) 2006-07-20 2017-07-19 Debiopharm International SA Acrylamide derivatives as FAB I inhibitors
WO2008098374A1 (en) 2007-02-16 2008-08-21 Affinium Pharmaceuticals, Inc. Salts, prodrugs and polymorphs of fab i inhibitors
JP5496915B2 (ja) 2008-02-13 2014-05-21 シージーアイ ファーマシューティカルズ，インコーポレーテッド ６−アリール−イミダゾ［１，２−ａ］ピラジン誘導体、その製造方法、及びその使用方法
EA021293B1 (ru) 2008-12-08 2015-05-29 Джилид Коннектикут, Инк. ИМИДАЗОПИРАЗИНОВЫЕ ИНГИБИТОРЫ Syk, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, СОДЕРЖАЩАЯ ИМИДАЗОПИРАЗИНОВЫЕ ИНГИБИТОРЫ Syk, И СПОСОБЫ ИХ ПРИМЕНЕНИЯ
CN102307474B (zh) 2008-12-08 2015-04-01 吉利德康涅狄格股份有限公司 咪唑并吡嗪syk抑制剂
US8450321B2 (en) 2008-12-08 2013-05-28 Gilead Connecticut, Inc. 6-(1H-indazol-6-yl)-N-[4-(morpholin-4-yl)phenyl]imidazo-[1,2-A]pyrazin-8-amine, or a pharmaceutically acceptable salt thereof, as a SYK inhibitor
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SI2861608T1 (sl) 2012-06-19 2019-08-30 Debiopharm International Sa Derivati predzdravila (E)-N-metil-N-((3-metilbenzofuran-2-IL)metil)- 3-(7-okso-5,6,7,8-tetrahidro-1 ,8-nafthiridin-3-il)akrilamid
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CA2919522C (en) 2013-07-30 2019-02-26 Gilead Connecticut, Inc. Formulation of syk inhibitors
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TWI662037B (zh) 2013-12-23 2019-06-11 美商基利科學股份有限公司 脾酪胺酸激酶抑制劑
US9290505B2 (en) 2013-12-23 2016-03-22 Gilead Sciences, Inc. Substituted imidazo[1,2-a]pyrazines as Syk inhibitors
BR112016028641A2 (pt) 2014-07-14 2017-08-22 Gilead Sciences Inc ?método para tratar câncer?
BR122023021456A2 (pt) 2016-02-26 2024-02-20 Debiopharm International S.A. Uso de di-hidrogeno fosfato de {6- [(e)-3-{metil[(3-metil-1-benfofuran-2- iol)metil]amino)-3- oxopro-1-en-1-il]-2-oxo-3,4-di-hidro-1,8-naftiridin-1(2h)- il}metila para tratamento de osteomielite do pé diabético e composição farmacêutica
CA3073871A1 (en) 2017-08-25 2019-02-28 Gilead Sciences, Inc. Polymorphs of syk inhibitors
LT3923914T (lt) 2019-02-14 2023-07-25 Debiopharm International S.A. Afabicino kompozicija, jos gamybos būdas
CN113950479A (zh) 2019-02-22 2022-01-18 克洛诺斯生物股份有限公司 作为syk抑制剂的缩合吡嗪的固体形式
CN113939306B (zh) 2019-06-14 2024-07-19 德彪药业国际股份公司 用于治疗涉及生物膜的细菌感染的药物及其用途

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Also Published As

Publication number Publication date
CZ292349B6 (cs) 2003-09-17
CN1284078A (zh) 2001-02-14
HK1030216A1 (en) 2001-04-27
HUP0100601A3 (en) 2002-10-28
US6518270B1 (en) 2003-02-11
TW515798B (en) 2003-01-01
NO20002721L (no) 2000-07-28
AR016972A1 (es) 2001-08-01
HUP0100601A2 (hu) 2001-09-28
TR200001530T2 (tr) 2000-11-21
PL340920A1 (en) 2001-03-12
JP2001525322A (ja) 2001-12-11
ID24730A (id) 2000-08-03
BR9814755A (pt) 2000-10-03
PT1042324E (pt) 2003-06-30
SE9704404D0 (sv) 1997-11-28
ES2191356T3 (es) 2003-09-01
CA2311798A1 (en) 1999-06-10
SK6742000A3 (en) 2001-03-12
EE200000315A (et) 2001-10-15
EP1042324A1 (en) 2000-10-11
RU2241000C2 (ru) 2004-11-27
NO20002721D0 (no) 2000-05-26
AU752187C (en) 2003-09-18
ZA9810468B (en) 1999-05-21
IS5486A (is) 2000-05-10
IL136145A0 (en) 2001-05-20
MY121032A (en) 2005-12-30
EE04060B1 (et) 2003-06-16
NO315704B1 (no) 2003-10-13
AU752187B2 (en) 2002-09-12
CN1142933C (zh) 2004-03-24
WO1999028322A1 (en) 1999-06-10
ATE233263T1 (de) 2003-03-15
DE69811735T2 (de) 2003-12-18
CZ20001947A3 (cs) 2000-11-15
SK283904B6 (sk) 2004-04-06
EP1042324B1 (en) 2003-02-26
UA70932C2 (uk) 2004-11-15
KR20010032559A (ko) 2001-04-25
AU1356599A (en) 1999-06-16
NZ504355A (en) 2001-12-21
DE69811735D1 (de) 2003-04-03

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