DK0957087T3 - Intermediater, der er anvendelige til fremstilling af enzym-inhibitorer - Google Patents

Intermediater, der er anvendelige til fremstilling af enzym-inhibitorer

Info

Publication number
DK0957087T3
DK0957087T3 DK99116304T DK99116304T DK0957087T3 DK 0957087 T3 DK0957087 T3 DK 0957087T3 DK 99116304 T DK99116304 T DK 99116304T DK 99116304 T DK99116304 T DK 99116304T DK 0957087 T3 DK0957087 T3 DK 0957087T3
Authority
DK
Denmark
Prior art keywords
preparation
enzyme inhibitors
intermediates useful
protecting group
intermediates
Prior art date
Application number
DK99116304T
Other languages
Danish (da)
English (en)
Inventor
Karl Witold Franzmann
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9509774.7A external-priority patent/GB9509774D0/en
Application filed by Wellcome Found filed Critical Wellcome Found
Application granted granted Critical
Publication of DK0957087T3 publication Critical patent/DK0957087T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C07C317/48—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
DK99116304T 1994-06-15 1995-06-14 Intermediater, der er anvendelige til fremstilling af enzym-inhibitorer DK0957087T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP94304314 1994-06-15
GBGB9509774.7A GB9509774D0 (en) 1995-05-15 1995-05-15 Enzyme inhibitors

Publications (1)

Publication Number Publication Date
DK0957087T3 true DK0957087T3 (da) 2003-03-24

Family

ID=26137155

Family Applications (2)

Application Number Title Priority Date Filing Date
DK95924405T DK0765308T3 (da) 1994-06-15 1995-06-14 Enzyminhibitorer
DK99116304T DK0957087T3 (da) 1994-06-15 1995-06-14 Intermediater, der er anvendelige til fremstilling af enzym-inhibitorer

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK95924405T DK0765308T3 (da) 1994-06-15 1995-06-14 Enzyminhibitorer

Country Status (29)

Country Link
US (2) US5889056A (fi)
EP (2) EP0957087B1 (fi)
JP (2) JP2989010B2 (fi)
KR (1) KR100430207B1 (fi)
CN (1) CN1070849C (fi)
AT (2) ATE191470T1 (fi)
AU (1) AU692892B2 (fi)
BR (1) BR9507995A (fi)
CA (1) CA2192668A1 (fi)
CY (2) CY2238B1 (fi)
DE (2) DE69516141T2 (fi)
DK (2) DK0765308T3 (fi)
ES (2) ES2145282T3 (fi)
FI (1) FI965019A (fi)
GR (1) GR3033746T3 (fi)
HK (1) HK1003935A1 (fi)
HU (1) HUT77407A (fi)
IL (2) IL114142A (fi)
IS (1) IS4384A (fi)
MX (1) MX9606136A (fi)
MY (1) MY115437A (fi)
NO (1) NO308655B1 (fi)
NZ (1) NZ289157A (fi)
PT (2) PT957087E (fi)
RU (1) RU2162841C2 (fi)
SI (2) SI0957087T1 (fi)
TW (1) TW442453B (fi)
WO (1) WO1995034534A1 (fi)
ZA (1) ZA954940B (fi)

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* Cited by examiner, † Cited by third party
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US6534503B1 (en) 1998-04-28 2003-03-18 Lion Bioscience Ag Melanocortin receptor-3 ligands to treat sexual dysfunction
EP1076649A4 (en) 1998-04-28 2010-06-02 Trega Biosciences Inc ISOQUINOLINE-BASED COMPOUNDS IN PLACE OF MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USE
US6284735B1 (en) * 1998-04-28 2001-09-04 Lion Bioscience Ag HP-3228 and related peptides to treat sexual dysfunction
GB9811599D0 (en) 1998-05-30 1998-07-29 Glaxo Group Ltd Nitric oxide synthase inhibitors
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DE10111049A1 (de) * 2001-03-06 2002-09-12 Beiersdorf Ag Verwendung von Substanzen, die verhindern, daß die NO-Synthese des warmblütigen Organismus ihre Wirkung entfaltet, zur Herstellung von kosmetischen oder dermatologischen Zubereitungen, zur Prophylaxe und Behandlung von entzündlichen Hautzuständen und/oder zum Hautschutz bei empfindlich determinierter trockener Haut
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EA200801997A1 (ru) 2006-04-20 2009-04-28 Глаксо Груп Лимитед Новые соединения
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JP2009545579A (ja) 2006-08-01 2009-12-24 グラクソ グループ リミテッド ピラゾロ［３，４−ｂ］ピリジン化合物、及びｐｄｅ４阻害薬としてのその使用
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DE3514450A1 (de) * 1985-04-22 1986-10-23 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von imidaten sowie neue arylsubstituierte imidate
GB9127376D0 (en) * 1991-12-24 1992-02-19 Wellcome Found Amidino derivatives
DE4310202A1 (de) * 1992-03-30 1993-10-07 Ciba Geigy µ-Ketoimidoester als Stabilisatoren für chlorhaltige Polymerisate
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Also Published As

Publication number Publication date
IL128717A0 (en) 2000-01-31
MY115437A (en) 2003-06-30
JP3614711B2 (ja) 2005-01-26
ES2145282T3 (es) 2000-07-01
WO1995034534A1 (en) 1995-12-21
ATE191470T1 (de) 2000-04-15
EP0957087B1 (en) 2002-12-04
TW442453B (en) 2001-06-23
NO308655B1 (no) 2000-10-09
ATE229001T1 (de) 2002-12-15
HUT77407A (hu) 1998-04-28
NO965379D0 (no) 1996-12-13
IL114142A (en) 2000-02-17
KR100430207B1 (ko) 2004-07-19
DE69529101T2 (de) 2003-11-13
HK1003935A1 (en) 1998-11-13
IL114142A0 (en) 1995-10-31
IS4384A (is) 1996-11-13
AU692892B2 (en) 1998-06-18
DE69516141T2 (de) 2000-10-19
RU2162841C2 (ru) 2001-02-10
JPH10506371A (ja) 1998-06-23
EP0957087A2 (en) 1999-11-17
ZA954940B (en) 1996-12-17
JP2000026402A (ja) 2000-01-25
JP2989010B2 (ja) 1999-12-13
CN1155276A (zh) 1997-07-23
NO965379L (no) 1996-12-13
HU9603454D0 (en) 1997-02-28
DE69516141D1 (de) 2000-05-11
CY2238B1 (en) 2003-07-04
AU2891795A (en) 1996-01-05
DK0765308T3 (da) 2000-09-11
CA2192668A1 (en) 1995-12-21
ES2189322T3 (es) 2003-07-01
MX9606136A (es) 1998-06-30
CY2455B1 (en) 2005-06-03
EP0957087A3 (en) 2000-12-20
FI965019A0 (fi) 1996-12-13
PT765308E (pt) 2000-09-29
EP0765308B1 (en) 2000-04-05
USRE39576E1 (en) 2007-04-17
DE69529101D1 (de) 2003-01-16
PT957087E (pt) 2003-04-30
US5889056A (en) 1999-03-30
SI0957087T1 (en) 2003-04-30
BR9507995A (pt) 1997-08-05
GR3033746T3 (en) 2000-10-31
SI0765308T1 (en) 2000-08-31
EP0765308A1 (en) 1997-04-02
CN1070849C (zh) 2001-09-12
FI965019A (fi) 1996-12-13
NZ289157A (en) 1998-03-25

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