DE69519182T2 - Azapeptid-Derivate - Google Patents
Azapeptid-DerivateInfo
- Publication number
- DE69519182T2 DE69519182T2 DE69519182T DE69519182T DE69519182T2 DE 69519182 T2 DE69519182 T2 DE 69519182T2 DE 69519182 T DE69519182 T DE 69519182T DE 69519182 T DE69519182 T DE 69519182T DE 69519182 T2 DE69519182 T2 DE 69519182T2
- Authority
- DE
- Germany
- Prior art keywords
- group
- protected
- salt
- lower alkyl
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/0606—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing heteroatoms not provided for by C07K5/06086 - C07K5/06139, e.g. Ser, Met, Cys, Thr
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06086—Dipeptides with the first amino acid being basic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0819—Tripeptides with the first amino acid being acidic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4720694 | 1994-03-17 | ||
JP8054794 | 1994-04-19 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69519182D1 DE69519182D1 (de) | 2000-11-30 |
DE69519182T2 true DE69519182T2 (de) | 2001-05-17 |
Family
ID=26387364
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69519182T Expired - Fee Related DE69519182T2 (de) | 1994-03-17 | 1995-03-17 | Azapeptid-Derivate |
Country Status (5)
Country | Link |
---|---|
US (2) | US5837687A (de) |
EP (1) | EP0672678B1 (de) |
KR (1) | KR100344607B1 (de) |
AT (1) | ATE197157T1 (de) |
DE (1) | DE69519182T2 (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998048826A1 (en) * | 1997-04-30 | 1998-11-05 | Northwestern University | Inhibition of nitric oxide synthase by amino acids and dipeptides |
US6624290B2 (en) | 2000-02-08 | 2003-09-23 | Schering Corporation | Azapeptides useful in the treatment of Hepatitis C |
CN1724514B (zh) * | 2004-07-19 | 2010-06-09 | 上海依福瑞实业有限公司 | 一种l-高精氨酸盐酸盐的制备方法 |
GB0516610D0 (en) * | 2005-08-12 | 2005-09-21 | Sosei Co Ltd | Compounds for use in therapy |
GB0614970D0 (en) * | 2006-07-27 | 2006-09-06 | R & D Sosei Ltd | Compounds For Use In Therapy |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0076557B1 (de) * | 1981-06-22 | 1985-11-13 | Imperial Chemical Industries Plc | Peptide und Pseudopeptide, die zwei Substituenten am N-Terminus aufweisen |
US5410019A (en) * | 1987-09-24 | 1995-04-25 | The Administrators Of The Tulane-Educational Fund | Therapeutic peptides |
US5164372A (en) * | 1989-04-28 | 1992-11-17 | Fujisawa Pharmaceutical Company, Ltd. | Peptide compounds having substance p antagonism, processes for preparation thereof and pharmaceutical composition comprising the same |
IT1233696B (it) * | 1989-05-29 | 1992-04-14 | Menarini Farma Ind | Peptidi di sintesi antagonisti della neurochinina a. loro sali e relativi procedimenti di fabbricazione |
GB8929070D0 (en) * | 1989-12-22 | 1990-02-28 | Fujisawa Pharmaceutical Co | Peptide compounds,processes for preparation thereof and pharmaceutical composition comprising the same |
US5420297A (en) * | 1990-10-24 | 1995-05-30 | Fujisawa Pharmaceutical Co., Ltd. | Peptides having substance P antagonistic activity |
FR2677362B1 (fr) * | 1991-06-04 | 1995-04-28 | Centre Nat Rech Scient | Neuropeptides de la famille des tachykinines. |
GB9112825D0 (en) * | 1991-06-14 | 1991-07-31 | Ici Plc | Process for making peptides |
US5654400A (en) * | 1991-10-04 | 1997-08-05 | Fujisawa Pharmaceutical Co., Ltd. | Process for making peptide compounds having tachykinin antagonistic activity |
FR2684674B1 (fr) * | 1991-12-10 | 1994-01-28 | Thevac Sarl | Azapeptides et leur procede de preparation. |
GB9319776D0 (en) * | 1993-09-24 | 1993-11-10 | Medical Res Council | Azapeptide synthesis |
-
1995
- 1995-03-17 US US08/406,053 patent/US5837687A/en not_active Expired - Fee Related
- 1995-03-17 DE DE69519182T patent/DE69519182T2/de not_active Expired - Fee Related
- 1995-03-17 KR KR1019950005568A patent/KR100344607B1/ko not_active IP Right Cessation
- 1995-03-17 AT AT95103948T patent/ATE197157T1/de not_active IP Right Cessation
- 1995-03-17 EP EP95103948A patent/EP0672678B1/de not_active Expired - Lifetime
-
1998
- 1998-08-24 US US09/138,656 patent/US5965538A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0672678A1 (de) | 1995-09-20 |
US5965538A (en) | 1999-10-12 |
DE69519182D1 (de) | 2000-11-30 |
KR100344607B1 (ko) | 2002-11-20 |
ATE197157T1 (de) | 2000-11-15 |
EP0672678B1 (de) | 2000-10-25 |
US5837687A (en) | 1998-11-17 |
KR950032271A (ko) | 1995-12-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |