FR2740339B1
(fr)
*
|
1995-10-26 |
1997-12-05 |
Oreal |
Utilisation d'au moins un inhibiteur de no-synthase dans le traitement des peaux sensibles
|
US6369272B1
(en)
|
1997-01-13 |
2002-04-09 |
Glaxosmithkline |
Nitric oxide synthase inhibitors
|
US6620848B2
(en)
|
1997-01-13 |
2003-09-16 |
Smithkline Beecham Corporation |
Nitric oxide synthase inhibitors
|
JP2001511151A
(ja)
*
|
1997-02-04 |
2001-08-07 |
ザ ジェネラル ホスピタル コーポレイション |
表皮又は皮膚疾患部の処理方法と形質転換動物
|
AU8647198A
(en)
*
|
1997-08-12 |
1999-03-01 |
Chugai Seiyaku Kabushiki Kaisha |
Remedies for diseases associated with bone resorption
|
US6344483B1
(en)
*
|
1998-03-11 |
2002-02-05 |
G. D. Searle & Co. |
Halogenated amidino amino acid deviratives useful as nitric oxide synthase inhibitors
|
US6284735B1
(en)
*
|
1998-04-28 |
2001-09-04 |
Lion Bioscience Ag |
HP-3228 and related peptides to treat sexual dysfunction
|
AU3768799A
(en)
|
1998-04-28 |
1999-11-16 |
Trega Biosciences, Inc. |
Isoquinoline compound melanocortin receptor ligands and methods of using same
|
US6534503B1
(en)
|
1998-04-28 |
2003-03-18 |
Lion Bioscience Ag |
Melanocortin receptor-3 ligands to treat sexual dysfunction
|
GB9811599D0
(en)
|
1998-05-30 |
1998-07-29 |
Glaxo Group Ltd |
Nitric oxide synthase inhibitors
|
AU6605800A
(en)
*
|
1999-07-16 |
2001-02-05 |
Trega Biosciences, Inc. |
Melanocortin receptor-3 ligands to treat sexual dysfunction
|
WO2001072703A1
(en)
*
|
2000-03-24 |
2001-10-04 |
Pharmacia Corporation |
Amidino compound and salts thereof useful as nitric oxide synthase inhibitors
|
AR034120A1
(es)
*
|
2000-04-13 |
2004-02-04 |
Pharmacia Corp |
Compuesto derivado halogenado del acido 2-amino-4,5 heptenoico, composicion farmaceutica que lo comprende y el uso de dicho compuesto y dicha composicion en la fabricacion de un medicamento para inhibir o modular la sintesis de acido nitrico
|
GB0031179D0
(en)
*
|
2000-12-21 |
2001-01-31 |
Glaxo Group Ltd |
Nitric oxide synthase inhibitors
|
DE10111054A1
(de)
*
|
2001-03-06 |
2002-09-12 |
Beiersdorf Ag |
Verwendung von Substanzen, die verhindern, daß die NO-Synthese des warmblütigen Organismus ihre Wirkung entfaltet, zur Herstellung von kosmetischen oder dermatologischen Zubereitungen zur Stärkung der Barrierefunktion der Haut
|
DE10111049A1
(de)
*
|
2001-03-06 |
2002-09-12 |
Beiersdorf Ag |
Verwendung von Substanzen, die verhindern, daß die NO-Synthese des warmblütigen Organismus ihre Wirkung entfaltet, zur Herstellung von kosmetischen oder dermatologischen Zubereitungen, zur Prophylaxe und Behandlung von entzündlichen Hautzuständen und/oder zum Hautschutz bei empfindlich determinierter trockener Haut
|
DE10111050A1
(de)
*
|
2001-03-06 |
2002-09-12 |
Beiersdorf Ag |
Verwendung von Substanzen, die verhindern, daß die NO-Synthase des warmblütigenOrganismus ihre Wirkung entfaltet, zur Herstellung von kosmetischewn oder dermatologischen Zubereitungen zur Behandlung und/oder Prophylaxe unerwünschter Hautpigmentierung
|
DE10111052A1
(de)
*
|
2001-03-06 |
2002-09-12 |
Beiersdorf Ag |
Verwendung von Substanzen, die verhindern, daß die NO-Synthase des warmblütigen Organismus ihre Wirkung entfaltet, zur Herstellung von kosmetischen oder dermatologischen Zubereitungen zur Steigerung der Ceramidbiosynthese
|
US7012098B2
(en)
*
|
2001-03-23 |
2006-03-14 |
Pharmacia Corporation |
Inhibitors of inducible nitric oxide synthase for chemoprevention and treatment of cancers
|
EP1505972A2
(en)
*
|
2002-05-16 |
2005-02-16 |
Pharmacia Corporation |
A selective inos inhibitor and a pde inhibitor in combination for the treatment of respiratory diseases
|
GB0214147D0
(en)
*
|
2002-06-19 |
2002-07-31 |
Glaxo Group Ltd |
Formulations
|
NZ574218A
(en)
*
|
2003-03-11 |
2009-11-27 |
Pharmacia Corp |
S-[2-[(1-iminoethyl)amino]ethyl]-2-methyl-L-cysteine maleate hydrochloride crystalline salt
|
TWI328009B
(en)
|
2003-05-21 |
2010-08-01 |
Glaxo Group Ltd |
Quinoline derivatives as phosphodiesterase inhibitors
|
GB0316290D0
(en)
|
2003-07-11 |
2003-08-13 |
Glaxo Group Ltd |
Novel compounds
|
PE20060272A1
(es)
|
2004-05-24 |
2006-05-22 |
Glaxo Group Ltd |
(2r,3r,4s,5r,2'r,3'r,4's,5's)-2,2'-{trans-1,4-ciclohexanodiilbis-[imino(2-{[2-(1-metil-1h-imidazol-4-il)etil]amino}-9h-purin-6,9-diil)]}bis[5-(2-etil-2h-tetrazol-5-il)tetrahidro-3,4-furanodiol] como agonista a2a
|
TWI307630B
(en)
|
2004-07-01 |
2009-03-21 |
Glaxo Group Ltd |
Immunoglobulins
|
GB0418045D0
(en)
|
2004-08-12 |
2004-09-15 |
Glaxo Group Ltd |
Compounds
|
EP1841780B1
(en)
|
2005-01-10 |
2011-07-27 |
Glaxo Group Limited |
Androstane 17-alpha-carbonate derivatives for use in the treatment of allergic and inflammatory conditions
|
TW200724142A
(en)
|
2005-03-25 |
2007-07-01 |
Glaxo Group Ltd |
Novel compounds
|
MY145281A
(en)
|
2005-03-25 |
2012-01-13 |
Glaxo Group Ltd |
Novel compounds
|
GB0514809D0
(en)
|
2005-07-19 |
2005-08-24 |
Glaxo Group Ltd |
Compounds
|
PE20071068A1
(es)
|
2005-12-20 |
2007-12-13 |
Glaxo Group Ltd |
Acido 3-(4-{[4-(4-{[3-(3,3-dimetil-1-piperidinil)propil]oxi}fenil)-1-piperidinil]carbonil}-1-naftalenil)propanoico o propenoico, sales de los mismos, como antagonistas de los receptores h1 y h3
|
MX2008013411A
(es)
|
2006-04-20 |
2008-11-04 |
Glaxo Group Ltd |
Nuevos compuestos.
|
GB0611587D0
(en)
|
2006-06-12 |
2006-07-19 |
Glaxo Group Ltd |
Novel compounds
|
US8003663B2
(en)
|
2006-08-01 |
2011-08-23 |
Glaxo Group Limited |
Pyrazolo[3,4-b]pyridine compounds, and their use as PDE4 inhibitors
|
US20080114021A1
(en)
*
|
2006-11-09 |
2008-05-15 |
University Of Maryland Baltimore |
Use Of 5,6-Dimethylxanthenone-4-Acetic Acid as an Antimicrobial Agent
|
AR065804A1
(es)
|
2007-03-23 |
2009-07-01 |
Smithkline Beecham Corp |
Compuesto de indol carboxamida, composicion farmaceutica que lo comprende y uso de dicho compuesto para preparar un medicamento
|
AU2009325091A1
(en)
|
2008-05-23 |
2010-06-17 |
Panmira Pharmaceuticals, Llc |
5-lipoxygenase-activating protein inhibitor
|
WO2009147190A1
(en)
|
2008-06-05 |
2009-12-10 |
Glaxo Group Limited |
Novel compounds
|
US8163743B2
(en)
|
2008-06-05 |
2012-04-24 |
GlaxoGroupLimited |
4-carboxamide indazole derivatives useful as inhibitors of PI3-kinases
|
WO2010094643A1
(en)
|
2009-02-17 |
2010-08-26 |
Glaxo Group Limited |
Quinoline derivatives and their uses for rhinitis and urticaria
|
US8524751B2
(en)
|
2009-03-09 |
2013-09-03 |
GlaxoSmithKline Intellecutual Property Development |
4-oxadiazol-2-YL-indazoles as inhibitors of P13 kinases
|
US8354539B2
(en)
|
2009-03-10 |
2013-01-15 |
Glaxo Group Limited |
Indole derivatives as IKK2 inhibitors
|
WO2010106016A1
(en)
|
2009-03-17 |
2010-09-23 |
Glaxo Group Limited |
Pyrimidine derivatives used as itk inhibitors
|
JP2012520686A
(ja)
|
2009-03-19 |
2012-09-10 |
メルク・シャープ・エンド・ドーム・コーポレイション |
低分子干渉核酸(siNA)を用いたシグナル伝達性転写因子6(STAT6)遺伝子発現のRNA干渉媒介性阻害
|
US20120029054A1
(en)
|
2009-03-19 |
2012-02-02 |
Merck Sharp & Dohme Corp. |
RNA Interference Mediated Inhibition of GATA Binding Protein 3 (GATA3) Gene Expression Using Short Intefering Nucleic Acid (siNA)
|
EP2408916A2
(en)
|
2009-03-19 |
2012-01-25 |
Merck Sharp&Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF CONNECTIVE TISSUE GROWTH FACTOR (CTGF) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
EA201171144A1
(ru)
|
2009-03-19 |
2012-04-30 |
Мерк Шарп Энд Домэ Корп. |
ОПОСРЕДОВАННОЕ РНК-ИНТЕРФЕРЕНЦИЕЙ ИНГИБИРОВАНИЕ ЭКСПРЕССИИ ГЕНА ГОМОЛОГА 1 BTB И CNC, ОСНОВНОГО ФАКТОРА ТРАНСКРИПЦИИ С ЛЕЙЦИНОВОЙ МОЛНИЕЙ 1 (Bach1) С ИСПОЛЬЗОВАНИЕМ МАЛОЙ ИНТЕРФЕРИРУЮЩЕЙ НУКЛЕИНОВОЙ КИСЛОТЫ (миНК)
|
JP2012521760A
(ja)
|
2009-03-27 |
2012-09-20 |
メルク・シャープ・エンド・ドーム・コーポレイション |
低分子干渉核酸(siNA)を用いたアポトーシスシグナル調節キナーゼ1(ASK1)遺伝子発現のRNA干渉媒介性阻害
|
JP2012521764A
(ja)
|
2009-03-27 |
2012-09-20 |
メルク・シャープ・エンド・ドーム・コーポレイション |
低分子干渉核酸(siNA)を用いた胸腺間質性リンパ球新生因子(TSLP)遺伝子発現のRNA干渉媒介性阻害
|
US20120004282A1
(en)
|
2009-03-27 |
2012-01-05 |
Merck Sharp & Dohme Corp, |
RNA Interference Mediated Inhibition of the Intercellular Adhesion Molecule 1 (ICAM-1) Gene Expression Using Short Interfering Nucleic Acid (siNA)
|
WO2010111468A2
(en)
|
2009-03-27 |
2010-09-30 |
Merck Sharp & Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF THE NERVE GROWTH FACTOR BETA CHAIN (NGFß) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (SINA)
|
WO2010111471A2
(en)
|
2009-03-27 |
2010-09-30 |
Merck Sharp & Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 1 (STAT1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
UY32571A
(es)
|
2009-04-24 |
2010-11-30 |
Glaxo Group Ltd |
Compuestos derivados de pirazol amida
|
WO2010122088A1
(en)
|
2009-04-24 |
2010-10-28 |
Glaxo Group Limited |
Pyrazole and triazole carboxamides as crac channel inhibitors
|
CA2759476C
(en)
|
2009-04-30 |
2018-10-09 |
Julie Nicole Hamblin |
Novel compounds
|
MX337575B
(es)
*
|
2009-10-09 |
2016-03-10 |
Zafgen Corp |
Compuestos de sulfona y métodos para lafabricación y uso de éstos.
|
WO2011067365A1
(en)
|
2009-12-03 |
2011-06-09 |
Glaxo Group Limited |
Benzpyrazole derivatives as inhibitors of p13 kinases
|
JP2013512878A
(ja)
|
2009-12-03 |
2013-04-18 |
グラクソ グループ リミテッド |
新規化合物
|
EP2507231A1
(en)
|
2009-12-03 |
2012-10-10 |
Glaxo Group Limited |
Indazole derivatives as pi 3 - kinase inhibitors
|
EP2512438B1
(en)
|
2009-12-16 |
2017-01-25 |
3M Innovative Properties Company |
Formulations and methods for controlling mdi particle size delivery
|
WO2011110575A1
(en)
|
2010-03-11 |
2011-09-15 |
Glaxo Group Limited |
Derivatives of 2-[2-(benzo- or pyrido-) thiazolylamino]-6-aminopyridine, useful in the treatment of respiratoric, allergic or inflammatory diseases
|
GB201007203D0
(en)
|
2010-04-29 |
2010-06-16 |
Glaxo Group Ltd |
Novel compounds
|
JP5876051B2
(ja)
|
2010-09-08 |
2016-03-02 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited |
インフルエンザウィルス感染の治療に使用するためのインダゾール誘導体
|
DK2614058T3
(en)
|
2010-09-08 |
2015-09-28 |
Glaxosmithkline Ip Dev Ltd |
Polymorphs, and the salts of N- [5- [4- (5 - {[(2R, 6S) -2,6-dimethyl-4-morpholinyl] methyl} -1,3-oxazol-2-yl) -1H-indazole -6-yl] -2- (methyloxy) -3-pyridinyl] methanesulfonamide.
|
WO2012035055A1
(en)
|
2010-09-17 |
2012-03-22 |
Glaxo Group Limited |
Novel compounds
|
WO2012052459A1
(en)
|
2010-10-21 |
2012-04-26 |
Glaxo Group Limited |
Pyrazole compounds acting against allergic, inflammatory and immune disorders
|
ES2532213T3
(es)
|
2010-10-21 |
2015-03-25 |
Glaxo Group Limited |
Compuestos de pirazol que actúan contra afecciones alérgicas, inmunitarias e inflamatorias
|
GB201018124D0
(en)
|
2010-10-27 |
2010-12-08 |
Glaxo Group Ltd |
Polymorphs and salts
|
GB201104153D0
(en)
|
2011-03-11 |
2011-04-27 |
Glaxo Group Ltd |
Novel compounds
|
WO2012123312A1
(en)
|
2011-03-11 |
2012-09-20 |
Glaxo Group Limited |
Pyrido[3,4-b]pyrazine derivatives as syk inhibitors
|
US9657007B2
(en)
|
2013-09-22 |
2017-05-23 |
Calitor Sciences, Llc |
Substituted aminopyrimidine compounds and methods of use
|
JP6517319B2
(ja)
|
2014-03-28 |
2019-05-22 |
キャリター・サイエンシーズ・リミテッド・ライアビリティ・カンパニーCalitor Sciences, Llc |
置換されたヘテロアリール化合物および使用方法
|
EA201692111A1
(ru)
|
2014-05-12 |
2017-08-31 |
Глаксосмитклайн Интеллекчуал Проперти (№ 2) Лимитед |
Фармацевтические композиции, содержащие данириксин, для лечения инфекционных заболеваний
|
GB201512635D0
(en)
|
2015-07-17 |
2015-08-26 |
Ucl Business Plc |
Uses of therapeutic compounds
|
EP3347097B1
(en)
|
2015-09-11 |
2021-02-24 |
Sunshine Lake Pharma Co., Ltd. |
Substituted aminopyrimidine derivatives as modulators of the kinases jak, flt3 and aurora
|
EP3710006A4
(en)
|
2017-11-19 |
2021-09-01 |
Sunshine Lake Pharma Co., Ltd. |
SUBSTITUTED HETEROARYL COMPOUNDS AND THEIR METHODS OF USE
|
AU2019209960B2
(en)
|
2018-01-20 |
2023-11-23 |
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Substituted aminopyrimidine compounds and methods of use
|
WO2021191875A1
(en)
|
2020-03-26 |
2021-09-30 |
Glaxosmithkline Intellectual Property Development Limited |
Cathepsin inhibitors for preventing or treating viral infections
|