SI0957087T1 - Intermediates useful in the preparation of enzyme inhibitors - Google Patents
Intermediates useful in the preparation of enzyme inhibitorsInfo
- Publication number
- SI0957087T1 SI0957087T1 SI9530645T SI9530645T SI0957087T1 SI 0957087 T1 SI0957087 T1 SI 0957087T1 SI 9530645 T SI9530645 T SI 9530645T SI 9530645 T SI9530645 T SI 9530645T SI 0957087 T1 SI0957087 T1 SI 0957087T1
- Authority
- SI
- Slovenia
- Prior art keywords
- preparation
- enzyme inhibitors
- intermediates useful
- protecting group
- intermediates
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
- C07C317/48—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Saccharide Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP94304314 | 1994-06-15 | ||
GBGB9509774.7A GB9509774D0 (en) | 1995-05-15 | 1995-05-15 | Enzyme inhibitors |
EP99116304A EP0957087B1 (en) | 1994-06-15 | 1995-06-14 | Intermediates useful in the preparation of enzyme inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
SI0957087T1 true SI0957087T1 (en) | 2003-04-30 |
Family
ID=26137155
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI9530645T SI0957087T1 (en) | 1994-06-15 | 1995-06-14 | Intermediates useful in the preparation of enzyme inhibitors |
SI9530412T SI0765308T1 (en) | 1994-06-15 | 1995-06-14 | Enzyme inhibitors |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI9530412T SI0765308T1 (en) | 1994-06-15 | 1995-06-14 | Enzyme inhibitors |
Country Status (29)
Country | Link |
---|---|
US (2) | US5889056A (fi) |
EP (2) | EP0957087B1 (fi) |
JP (2) | JP2989010B2 (fi) |
KR (1) | KR100430207B1 (fi) |
CN (1) | CN1070849C (fi) |
AT (2) | ATE191470T1 (fi) |
AU (1) | AU692892B2 (fi) |
BR (1) | BR9507995A (fi) |
CA (1) | CA2192668A1 (fi) |
CY (2) | CY2238B1 (fi) |
DE (2) | DE69529101T2 (fi) |
DK (2) | DK0765308T3 (fi) |
ES (2) | ES2145282T3 (fi) |
FI (1) | FI965019A (fi) |
GR (1) | GR3033746T3 (fi) |
HK (1) | HK1003935A1 (fi) |
HU (1) | HUT77407A (fi) |
IL (2) | IL114142A (fi) |
IS (1) | IS4384A (fi) |
MX (1) | MX9606136A (fi) |
MY (1) | MY115437A (fi) |
NO (1) | NO308655B1 (fi) |
NZ (1) | NZ289157A (fi) |
PT (2) | PT765308E (fi) |
RU (1) | RU2162841C2 (fi) |
SI (2) | SI0957087T1 (fi) |
TW (1) | TW442453B (fi) |
WO (1) | WO1995034534A1 (fi) |
ZA (1) | ZA954940B (fi) |
Families Citing this family (79)
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FR2740339B1 (fr) * | 1995-10-26 | 1997-12-05 | Oreal | Utilisation d'au moins un inhibiteur de no-synthase dans le traitement des peaux sensibles |
US6369272B1 (en) | 1997-01-13 | 2002-04-09 | Glaxosmithkline | Nitric oxide synthase inhibitors |
US6620848B2 (en) | 1997-01-13 | 2003-09-16 | Smithkline Beecham Corporation | Nitric oxide synthase inhibitors |
US6160021A (en) * | 1997-02-04 | 2000-12-12 | The General Hospital Corporation | Method for treating epidermal or dermal conditions |
AU8647198A (en) * | 1997-08-12 | 1999-03-01 | Chugai Seiyaku Kabushiki Kaisha | Remedies for diseases associated with bone resorption |
DE69920670T2 (de) | 1998-03-11 | 2006-02-16 | G.D. Searle & Co., Chicago | Halogenierte aminosäure derivate als hemmstoffe der stickstoffmonoxid-synthase |
US6534503B1 (en) | 1998-04-28 | 2003-03-18 | Lion Bioscience Ag | Melanocortin receptor-3 ligands to treat sexual dysfunction |
US6284735B1 (en) * | 1998-04-28 | 2001-09-04 | Lion Bioscience Ag | HP-3228 and related peptides to treat sexual dysfunction |
WO1999055679A1 (en) | 1998-04-28 | 1999-11-04 | Trega Biosciences, Inc. | Isoquinoline compound melanocortin receptor ligands and methods of using same |
GB9811599D0 (en) | 1998-05-30 | 1998-07-29 | Glaxo Group Ltd | Nitric oxide synthase inhibitors |
WO2001005401A1 (en) * | 1999-07-16 | 2001-01-25 | Trega Biosciences, Inc. | Melanocortin receptor-3 ligands to treat sexual dysfunction |
KR100835265B1 (ko) * | 2000-03-24 | 2008-06-09 | 파마시아 코포레이션 | 산화 질소 신타아제 억제제로 유용한 아미디노 화합물 및그들의 염 |
AR034120A1 (es) * | 2000-04-13 | 2004-02-04 | Pharmacia Corp | Compuesto derivado halogenado del acido 2-amino-4,5 heptenoico, composicion farmaceutica que lo comprende y el uso de dicho compuesto y dicha composicion en la fabricacion de un medicamento para inhibir o modular la sintesis de acido nitrico |
GB0031179D0 (en) * | 2000-12-21 | 2001-01-31 | Glaxo Group Ltd | Nitric oxide synthase inhibitors |
DE10111054A1 (de) * | 2001-03-06 | 2002-09-12 | Beiersdorf Ag | Verwendung von Substanzen, die verhindern, daß die NO-Synthese des warmblütigen Organismus ihre Wirkung entfaltet, zur Herstellung von kosmetischen oder dermatologischen Zubereitungen zur Stärkung der Barrierefunktion der Haut |
DE10111050A1 (de) * | 2001-03-06 | 2002-09-12 | Beiersdorf Ag | Verwendung von Substanzen, die verhindern, daß die NO-Synthase des warmblütigenOrganismus ihre Wirkung entfaltet, zur Herstellung von kosmetischewn oder dermatologischen Zubereitungen zur Behandlung und/oder Prophylaxe unerwünschter Hautpigmentierung |
DE10111052A1 (de) * | 2001-03-06 | 2002-09-12 | Beiersdorf Ag | Verwendung von Substanzen, die verhindern, daß die NO-Synthase des warmblütigen Organismus ihre Wirkung entfaltet, zur Herstellung von kosmetischen oder dermatologischen Zubereitungen zur Steigerung der Ceramidbiosynthese |
DE10111049A1 (de) * | 2001-03-06 | 2002-09-12 | Beiersdorf Ag | Verwendung von Substanzen, die verhindern, daß die NO-Synthese des warmblütigen Organismus ihre Wirkung entfaltet, zur Herstellung von kosmetischen oder dermatologischen Zubereitungen, zur Prophylaxe und Behandlung von entzündlichen Hautzuständen und/oder zum Hautschutz bei empfindlich determinierter trockener Haut |
US7012098B2 (en) * | 2001-03-23 | 2006-03-14 | Pharmacia Corporation | Inhibitors of inducible nitric oxide synthase for chemoprevention and treatment of cancers |
JP2005532321A (ja) * | 2002-05-16 | 2005-10-27 | ファルマシア コーポレーション | 呼吸器の疾患および状態の、選択的iNOS阻害剤とPDE阻害剤による治療方法、ならびにそのための組成物 |
GB0214147D0 (en) * | 2002-06-19 | 2002-07-31 | Glaxo Group Ltd | Formulations |
AU2004220266B2 (en) * | 2003-03-11 | 2010-08-19 | Pharmacia Corporation | S-[2-[(1-Iminoethyl)amino]ethyl]-2-methyl-L-cysteine maleate hydrochloride crystalline salt |
TWI328009B (en) | 2003-05-21 | 2010-08-01 | Glaxo Group Ltd | Quinoline derivatives as phosphodiesterase inhibitors |
GB0316290D0 (en) | 2003-07-11 | 2003-08-13 | Glaxo Group Ltd | Novel compounds |
PE20060272A1 (es) | 2004-05-24 | 2006-05-22 | Glaxo Group Ltd | (2r,3r,4s,5r,2'r,3'r,4's,5's)-2,2'-{trans-1,4-ciclohexanodiilbis-[imino(2-{[2-(1-metil-1h-imidazol-4-il)etil]amino}-9h-purin-6,9-diil)]}bis[5-(2-etil-2h-tetrazol-5-il)tetrahidro-3,4-furanodiol] como agonista a2a |
TWI307630B (en) | 2004-07-01 | 2009-03-21 | Glaxo Group Ltd | Immunoglobulins |
GB0418045D0 (en) | 2004-08-12 | 2004-09-15 | Glaxo Group Ltd | Compounds |
ATE517908T1 (de) | 2005-01-10 | 2011-08-15 | Glaxo Group Ltd | Androstan-17-alpha-carbonat-derivate zur verwendung bei der behandlung allergischer und entzündlicher zustände |
PE20061351A1 (es) | 2005-03-25 | 2007-01-14 | Glaxo Group Ltd | COMPUESTOS 8H-PIRIDO[2,3-d]PIRIMIDIN-7-ONA 2,4,8-TRISUSTITUIDOS COMO INHIBIDORES DE LA QUINASA CSBP/RK/p38 |
TW200724142A (en) | 2005-03-25 | 2007-07-01 | Glaxo Group Ltd | Novel compounds |
GB0514809D0 (en) | 2005-07-19 | 2005-08-24 | Glaxo Group Ltd | Compounds |
TW200730498A (en) | 2005-12-20 | 2007-08-16 | Glaxo Group Ltd | Compounds |
US8178573B2 (en) | 2006-04-20 | 2012-05-15 | Glaxo Group Limited | Compounds |
GB0611587D0 (en) | 2006-06-12 | 2006-07-19 | Glaxo Group Ltd | Novel compounds |
PT2046787E (pt) | 2006-08-01 | 2011-06-15 | Glaxo Group Ltd | Compostos de pirazolo[3,4-b]piridina e sua utilização como inibidores de pde4 |
WO2008147445A2 (en) * | 2006-11-09 | 2008-12-04 | University Of Maryland, Baltimore | Use of 5,6-dimethylxanthenone-4-acetic acid as an antimicrobial agent |
AR065804A1 (es) | 2007-03-23 | 2009-07-01 | Smithkline Beecham Corp | Compuesto de indol carboxamida, composicion farmaceutica que lo comprende y uso de dicho compuesto para preparar un medicamento |
EP2285803A4 (en) | 2008-05-23 | 2011-10-05 | Amira Pharmaceuticals Inc | Inhibitor of 5-Lipoxygenase Activating Protein |
JP5502858B2 (ja) | 2008-06-05 | 2014-05-28 | グラクソ グループ リミテッド | Pi3キナーゼの阻害剤として有用な4−カルボキサミドインダゾール誘導体 |
ATE552255T1 (de) | 2008-06-05 | 2012-04-15 | Glaxo Group Ltd | 4-aminoindazole |
WO2010094643A1 (en) | 2009-02-17 | 2010-08-26 | Glaxo Group Limited | Quinoline derivatives and their uses for rhinitis and urticaria |
JP5656880B2 (ja) | 2009-03-09 | 2015-01-21 | グラクソ グループ リミテッドGlaxo Group Limited | Pi3キナーゼの阻害剤としての4−オキサジアゾール−2−イル−インダゾール |
WO2010102968A1 (en) | 2009-03-10 | 2010-09-16 | Glaxo Group Limited | Indole derivatives as ikk2 inhibitors |
WO2010106016A1 (en) | 2009-03-17 | 2010-09-23 | Glaxo Group Limited | Pyrimidine derivatives used as itk inhibitors |
WO2010107957A2 (en) | 2009-03-19 | 2010-09-23 | Merck Sharp & Dohme Corp. | RNA INTERFERENCE MEDIATED INHIBITION OF GATA BINDING PROTEIN 3 (GATA3) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) |
CN102439151A (zh) | 2009-03-19 | 2012-05-02 | 默沙东公司 | 使用短干扰核酸(siNA)的RNA干扰介导的BTB和CNC同系物1,碱性亮氨酸拉链转录因子1(Bach1)基因表达的抑制 |
WO2010107952A2 (en) | 2009-03-19 | 2010-09-23 | Merck Sharp & Dohme Corp. | RNA INTERFERENCE MEDIATED INHIBITION OF CONNECTIVE TISSUE GROWTH FACTOR (CTGF) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) |
EP2408458A1 (en) | 2009-03-19 | 2012-01-25 | Merck Sharp&Dohme Corp. | RNA INTERFERENCE MEDIATED INHIBITION OF SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 6 (STAT6) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) |
JP2012521765A (ja) | 2009-03-27 | 2012-09-20 | メルク・シャープ・エンド・ドーム・コーポレイション | 低分子干渉核酸(siNA)を用いた細胞内接着分子1(ICAM−1)遺伝子発現のRNA干渉媒介性阻害 |
US20120004281A1 (en) | 2009-03-27 | 2012-01-05 | Merck Sharp & Dohme Corp | RNA Interference Mediated Inhibition of the Nerve Growth Factor Beta Chain (NGFB) Gene Expression Using Short Interfering Nucleic Acid (siNA) |
US20120022142A1 (en) | 2009-03-27 | 2012-01-26 | Merck Sharp & Dohme Corp. | RNA Interference Mediated Inhibition of Signal Transducer and Activator of Transcription 1 (STAT1) Gene Expression Using Short Interfering Nucleic Acid (siNA) |
WO2010111464A1 (en) | 2009-03-27 | 2010-09-30 | Merck Sharp & Dohme Corp. | RNA INTERFERENCE MEDIATED INHIBITION OF APOPTOSIS SIGNAL-REGULATING KINASE 1 (ASK1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) |
WO2010111490A2 (en) | 2009-03-27 | 2010-09-30 | Merck Sharp & Dohme Corp. | RNA INTERFERENCE MEDIATED INHIBITION OF THE THYMIC STROMAL LYMPHOPOIETIN (TSLP) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) |
EP2421835A1 (en) | 2009-04-24 | 2012-02-29 | Glaxo Group Limited | N-pyrazolyl carboxamides as crac channel inhibitors |
EP2421834A1 (en) | 2009-04-24 | 2012-02-29 | Glaxo Group Limited | Pyrazole and triazole carboxamides as crac channel inhibitors |
AU2010243613B2 (en) | 2009-04-30 | 2015-05-07 | Glaxo Group Limited | Oxazole substituted indazoles as PI3-kinase inhibitors |
CA2777108A1 (en) * | 2009-10-09 | 2011-04-14 | Zafgen Corporation | Sulphone compounds and methods of making and using same |
WO2011067366A1 (en) | 2009-12-03 | 2011-06-09 | Glaxo Group Limited | Indazole derivatives as pi 3 - kinase inhibitors |
US20120245171A1 (en) | 2009-12-03 | 2012-09-27 | Glaxo Group Limited | Benzpyrazole derivatives as inhibitors of pi3 kinases |
US20120238559A1 (en) | 2009-12-03 | 2012-09-20 | Glaxo Group Limited | Novel compounds |
EP3020393B1 (en) | 2009-12-16 | 2020-10-07 | 3M Innovative Properties Company | Formulations and methods for controlling mdi particle size delivery |
WO2011110575A1 (en) | 2010-03-11 | 2011-09-15 | Glaxo Group Limited | Derivatives of 2-[2-(benzo- or pyrido-) thiazolylamino]-6-aminopyridine, useful in the treatment of respiratoric, allergic or inflammatory diseases |
GB201007203D0 (en) | 2010-04-29 | 2010-06-16 | Glaxo Group Ltd | Novel compounds |
US9326987B2 (en) | 2010-09-08 | 2016-05-03 | Glaxo Group Limited | Indazole derivatives for use in the treatment of influenza virus infection |
HUE026059T2 (en) | 2010-09-08 | 2016-05-30 | Glaxosmithkline Ip Dev Ltd | N- [5- [4- (5 - {[(2R, 6S) -2,6-dimethyl-4-morpholinyl] methyl} -1,3-oxazol-2-yl) -1H-indazol-6-yl ] Polymorphs and salts of 2 - (methyloxy) -3-pyridinyl] methanesulfonamide |
WO2012035055A1 (en) | 2010-09-17 | 2012-03-22 | Glaxo Group Limited | Novel compounds |
EP2630127A1 (en) | 2010-10-21 | 2013-08-28 | Glaxo Group Limited | Pyrazole compounds acting against allergic, inflammatory and immune disorders |
EP2630126B1 (en) | 2010-10-21 | 2015-01-07 | Glaxo Group Limited | Pyrazole compounds acting against allergic, immune and inflammatory conditions |
GB201018124D0 (en) | 2010-10-27 | 2010-12-08 | Glaxo Group Ltd | Polymorphs and salts |
GB201104153D0 (en) | 2011-03-11 | 2011-04-27 | Glaxo Group Ltd | Novel compounds |
US20140005188A1 (en) | 2011-03-11 | 2014-01-02 | Glaxo Group Limited | Pyrido[3,4-b]pyrazine derivatives as syk inhibitors |
KR20160060100A (ko) | 2013-09-22 | 2016-05-27 | 칼리토르 사이언시즈, 엘엘씨 | 치환된 아미노피리미딘 화합물 및 이용 방법 |
JP6517319B2 (ja) | 2014-03-28 | 2019-05-22 | キャリター・サイエンシーズ・リミテッド・ライアビリティ・カンパニーCalitor Sciences, Llc | 置換されたヘテロアリール化合物および使用方法 |
US20170100385A1 (en) | 2014-05-12 | 2017-04-13 | Glaxosmithkline Intellectual Property (No. 2) Limited | Pharmaceutical compositions comprising danirixin for treating infectious diseases |
GB201512635D0 (en) | 2015-07-17 | 2015-08-26 | Ucl Business Plc | Uses of therapeutic compounds |
EP3347097B1 (en) | 2015-09-11 | 2021-02-24 | Sunshine Lake Pharma Co., Ltd. | Substituted aminopyrimidine derivatives as modulators of the kinases jak, flt3 and aurora |
US10683297B2 (en) | 2017-11-19 | 2020-06-16 | Calitor Sciences, Llc | Substituted heteroaryl compounds and methods of use |
AU2019209960B2 (en) | 2018-01-20 | 2023-11-23 | Sunshine Lake Pharma Co., Ltd. | Substituted aminopyrimidine compounds and methods of use |
WO2021191875A1 (en) | 2020-03-26 | 2021-09-30 | Glaxosmithkline Intellectual Property Development Limited | Cathepsin inhibitors for preventing or treating viral infections |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3514450A1 (de) * | 1985-04-22 | 1986-10-23 | Hoechst Ag, 6230 Frankfurt | Verfahren zur herstellung von imidaten sowie neue arylsubstituierte imidate |
GB9127376D0 (en) | 1991-12-24 | 1992-02-19 | Wellcome Found | Amidino derivatives |
DE4310202A1 (de) * | 1992-03-30 | 1993-10-07 | Ciba Geigy | µ-Ketoimidoester als Stabilisatoren für chlorhaltige Polymerisate |
FR2727111B1 (fr) * | 1994-11-21 | 1997-01-17 | Hoechst Lab | Nouveaux analogues soufres d'aminoacides, leur procede de preparation et leurs applications comme medicaments |
-
1995
- 1995-06-14 DE DE69529101T patent/DE69529101T2/de not_active Expired - Lifetime
- 1995-06-14 BR BR9507995A patent/BR9507995A/pt not_active IP Right Cessation
- 1995-06-14 HU HU9603454A patent/HUT77407A/hu unknown
- 1995-06-14 SI SI9530645T patent/SI0957087T1/xx unknown
- 1995-06-14 ES ES95924405T patent/ES2145282T3/es not_active Expired - Lifetime
- 1995-06-14 US US08/750,679 patent/US5889056A/en not_active Ceased
- 1995-06-14 JP JP8501803A patent/JP2989010B2/ja not_active Expired - Lifetime
- 1995-06-14 IL IL11414295A patent/IL114142A/xx not_active IP Right Cessation
- 1995-06-14 AT AT95924405T patent/ATE191470T1/de not_active IP Right Cessation
- 1995-06-14 PT PT95924405T patent/PT765308E/pt unknown
- 1995-06-14 ES ES99116304T patent/ES2189322T3/es not_active Expired - Lifetime
- 1995-06-14 DE DE69516141T patent/DE69516141T2/de not_active Expired - Fee Related
- 1995-06-14 NZ NZ289157A patent/NZ289157A/en not_active IP Right Cessation
- 1995-06-14 PT PT99116304T patent/PT957087E/pt unknown
- 1995-06-14 RU RU97100747/04A patent/RU2162841C2/ru not_active IP Right Cessation
- 1995-06-14 AT AT99116304T patent/ATE229001T1/de not_active IP Right Cessation
- 1995-06-14 DK DK95924405T patent/DK0765308T3/da active
- 1995-06-14 CA CA002192668A patent/CA2192668A1/en not_active Abandoned
- 1995-06-14 CN CN95194518A patent/CN1070849C/zh not_active Expired - Fee Related
- 1995-06-14 KR KR1019960707192A patent/KR100430207B1/ko not_active IP Right Cessation
- 1995-06-14 EP EP99116304A patent/EP0957087B1/en not_active Expired - Lifetime
- 1995-06-14 WO PCT/GB1995/001378 patent/WO1995034534A1/en active IP Right Grant
- 1995-06-14 EP EP95924405A patent/EP0765308B1/en not_active Expired - Lifetime
- 1995-06-14 AU AU28917/95A patent/AU692892B2/en not_active Ceased
- 1995-06-14 US US10/407,204 patent/USRE39576E1/en not_active Expired - Lifetime
- 1995-06-14 SI SI9530412T patent/SI0765308T1/xx unknown
- 1995-06-14 DK DK99116304T patent/DK0957087T3/da active
- 1995-06-14 ZA ZA954940A patent/ZA954940B/xx unknown
- 1995-06-15 MY MYPI95001621A patent/MY115437A/en unknown
- 1995-07-15 TW TW084107349A patent/TW442453B/zh not_active IP Right Cessation
-
1996
- 1996-11-13 IS IS4384A patent/IS4384A/is unknown
- 1996-12-05 MX MX9606136A patent/MX9606136A/es not_active IP Right Cessation
- 1996-12-13 FI FI965019A patent/FI965019A/fi not_active Application Discontinuation
- 1996-12-13 NO NO965379A patent/NO308655B1/no unknown
-
1998
- 1998-04-17 HK HK98103253A patent/HK1003935A1/xx not_active IP Right Cessation
-
1999
- 1999-02-25 IL IL12871799A patent/IL128717A0/xx not_active IP Right Cessation
- 1999-06-07 JP JP16019399A patent/JP3614711B2/ja not_active Expired - Fee Related
-
2000
- 2000-06-22 GR GR20000401441T patent/GR3033746T3/el not_active IP Right Cessation
-
2001
- 2001-09-07 CY CY0100026A patent/CY2238B1/xx unknown
-
2004
- 2004-06-03 CY CY0400042A patent/CY2455B1/xx unknown
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