DK0934310T3 - Thiosyreafledte, monocykliske forbindelser som antikoaguleringsmidler - Google Patents

Thiosyreafledte, monocykliske forbindelser som antikoaguleringsmidler

Info

Publication number
DK0934310T3
DK0934310T3 DK97944891T DK97944891T DK0934310T3 DK 0934310 T3 DK0934310 T3 DK 0934310T3 DK 97944891 T DK97944891 T DK 97944891T DK 97944891 T DK97944891 T DK 97944891T DK 0934310 T3 DK0934310 T3 DK 0934310T3
Authority
DK
Denmark
Prior art keywords
anticoagulants
thioic acid
monocyclic compounds
compounds
derived
Prior art date
Application number
DK97944891T
Other languages
Danish (da)
English (en)
Inventor
Michael M Morrissey
Howard P Ng
Monica J Kochanny
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Application granted granted Critical
Publication of DK0934310T3 publication Critical patent/DK0934310T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
  • Pyridine Compounds (AREA)
DK97944891T 1996-10-09 1997-09-24 Thiosyreafledte, monocykliske forbindelser som antikoaguleringsmidler DK0934310T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/731,128 US6004985A (en) 1996-10-09 1996-10-09 Thio acid derived monocylic N-heterocyclics as anticoagulants
PCT/EP1997/005231 WO1998015547A1 (en) 1996-10-09 1997-09-24 Thio acid derived monocyclic n-heterocyclics as anticoagulants

Publications (1)

Publication Number Publication Date
DK0934310T3 true DK0934310T3 (da) 2005-05-30

Family

ID=24938188

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97944891T DK0934310T3 (da) 1996-10-09 1997-09-24 Thiosyreafledte, monocykliske forbindelser som antikoaguleringsmidler

Country Status (21)

Country Link
US (6) US6004985A (cs)
EP (1) EP0934310B1 (cs)
JP (1) JP3768244B2 (cs)
KR (1) KR20000048966A (cs)
CN (1) CN1111159C (cs)
AT (1) ATE288908T1 (cs)
AU (1) AU730060B2 (cs)
CA (1) CA2268172A1 (cs)
CZ (1) CZ122799A3 (cs)
DE (1) DE69732490T2 (cs)
DK (1) DK0934310T3 (cs)
ES (1) ES2236828T3 (cs)
HK (1) HK1020958A1 (cs)
HU (1) HUP9904180A3 (cs)
IL (1) IL129056A0 (cs)
NO (1) NO991594L (cs)
NZ (1) NZ334758A (cs)
PL (1) PL332602A1 (cs)
PT (1) PT934310E (cs)
SK (1) SK46499A3 (cs)
WO (1) WO1998015547A1 (cs)

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US6960705B2 (en) 1998-10-05 2005-11-01 Eden Bioscience Corporation Nucleic acid encoding a hypersensitive response elicitor from Xanthomonas campestris
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TWI329105B (en) 2002-02-01 2010-08-21 Rigel Pharmaceuticals Inc 2,4-pyrimidinediamine compounds and their uses
GB0206215D0 (en) 2002-03-15 2002-05-01 Novartis Ag Organic compounds
TW200409629A (en) 2002-06-27 2004-06-16 Bristol Myers Squibb Co 2,4-disubstituted-pyridine N-oxides useful as HIV reverse transcriptase inhibitors
CN1678321A (zh) 2002-07-29 2005-10-05 里格尔药品股份有限公司 用2,4－嘧啶二胺化合物治疗或者预防自体免疫性疾病的方法
US7419984B2 (en) * 2002-10-17 2008-09-02 Cell Therapeutics, Inc. Pyrimidines and uses thereof
KR20040042071A (ko) * 2002-11-12 2004-05-20 박영민 인터넷 홈페이지를 활용한 경조사 자동알림 및 게시판 자동등록 방법
HUE025683T2 (hu) 2002-12-03 2016-04-28 Pharmacyclics Llc VIIA faktor inhibitor 2-(2-hidroxi-bifenil-3-il)-1H-benzoimidazol-5-karboxamidin-származékok
US6875781B2 (en) * 2003-04-04 2005-04-05 Cell Therapeutics, Inc. Pyridines and uses thereof
US7122542B2 (en) * 2003-07-30 2006-10-17 Rigel Pharmaceuticals, Inc. Methods of treating or preventing autoimmune diseases with 2,4-pyrimidinediamine compounds
DK1814878T3 (da) * 2004-11-24 2012-05-07 Rigel Pharmaceuticals Inc Spiro-2, 4-pyrimidindiamin-forbindelser og anvendelser deraf
DK1856135T3 (da) 2005-01-19 2010-04-12 Rigel Pharmaceuticals Inc Prodrugs af 2,4-pyrimidindiamin-forbindelser og deres anvendelser
US20060270694A1 (en) * 2005-05-03 2006-11-30 Rigel Pharmaceuticals, Inc. JAK kinase inhibitors and their uses
US20070015834A1 (en) * 2005-07-18 2007-01-18 Moshe Flashner-Barak Formulations of fenofibrate containing PEG/Poloxamer
US8138339B2 (en) 2008-04-16 2012-03-20 Portola Pharmaceuticals, Inc. Inhibitors of protein kinases
ES2546502T3 (es) * 2008-04-16 2015-09-24 Portola Pharmaceuticals, Inc. 2,6-Diamino-pirimidin-5-il-carboxamidas como inhibidores de syk o JAK quinasas
MX2010012703A (es) 2008-05-21 2010-12-21 Ariad Pharma Inc Derivados fosforosos como inhibidores de cinasa.
US9273077B2 (en) 2008-05-21 2016-03-01 Ariad Pharmaceuticals, Inc. Phosphorus derivatives as kinase inhibitors
AU2012250517B2 (en) 2011-05-04 2016-05-19 Takeda Pharmaceutical Company Limited Compounds for inhibiting cell proliferation in EGFR-driven cancers
MX363551B (es) 2011-11-23 2019-03-27 Portola Pharmaceuticals Inc Star Compuestos derivados de pirazina como inhibidores de cinasa.
JP6469567B2 (ja) 2012-05-05 2019-02-13 アリアド・ファーマシューティカルズ・インコーポレイテッド Ｅｇｆｒ発動性がんの細胞増殖阻害用化合物
US9611283B1 (en) 2013-04-10 2017-04-04 Ariad Pharmaceuticals, Inc. Methods for inhibiting cell proliferation in ALK-driven cancers
US10676436B2 (en) * 2018-07-05 2020-06-09 Landos Biopharma, Inc. NLRX1 ligands
US10487057B1 (en) * 2018-07-05 2019-11-26 Landos Biopharma, Inc. NLRX1 ligands
CN113527193B (zh) * 2020-04-18 2022-06-10 中国科学院精密测量科学与技术创新研究院 一种用于核磁氟谱检测的探针及其在检测巯基类化合物中的应用

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Also Published As

Publication number Publication date
PT934310E (pt) 2005-06-30
CN1233247A (zh) 1999-10-27
NZ334758A (en) 2000-11-24
CA2268172A1 (en) 1998-04-16
EP0934310A1 (en) 1999-08-11
US6004985A (en) 1999-12-21
US6166014A (en) 2000-12-26
NO991594D0 (no) 1999-03-31
HUP9904180A2 (hu) 2000-09-28
US6150382A (en) 2000-11-21
EP0934310B1 (en) 2005-02-09
NO991594L (no) 1999-06-08
HK1020958A1 (en) 2004-03-19
SK46499A3 (en) 2000-04-10
JP3768244B2 (ja) 2006-04-19
WO1998015547A1 (en) 1998-04-16
CN1111159C (zh) 2003-06-11
US6162807A (en) 2000-12-19
CZ122799A3 (cs) 1999-09-15
US6221886B1 (en) 2001-04-24
DE69732490T2 (de) 2006-04-27
PL332602A1 (en) 1999-09-27
DE69732490D1 (en) 2005-03-17
AU4624097A (en) 1998-05-05
ES2236828T3 (es) 2005-07-16
US6034084A (en) 2000-03-07
HUP9904180A3 (en) 2000-11-28
ATE288908T1 (de) 2005-02-15
AU730060B2 (en) 2001-02-22
JP2001501632A (ja) 2001-02-06
KR20000048966A (ko) 2000-07-25
IL129056A0 (en) 2000-02-17

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