IL129056A0 - Monocyclic N-heterocyclics substituted by thio acid derivatives and pharmaceutical compositions containing same - Google Patents

Monocyclic N-heterocyclics substituted by thio acid derivatives and pharmaceutical compositions containing same

Info

Publication number
IL129056A0
IL129056A0 IL12905697A IL12905697A IL129056A0 IL 129056 A0 IL129056 A0 IL 129056A0 IL 12905697 A IL12905697 A IL 12905697A IL 12905697 A IL12905697 A IL 12905697A IL 129056 A0 IL129056 A0 IL 129056A0
Authority
IL
Israel
Prior art keywords
monocyclic
pharmaceutical compositions
compositions containing
acid derivatives
containing same
Prior art date
Application number
IL12905697A
Other languages
English (en)
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of IL129056A0 publication Critical patent/IL129056A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
IL12905697A 1996-10-09 1997-09-24 Monocyclic N-heterocyclics substituted by thio acid derivatives and pharmaceutical compositions containing same IL129056A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/731,128 US6004985A (en) 1996-10-09 1996-10-09 Thio acid derived monocylic N-heterocyclics as anticoagulants
PCT/EP1997/005231 WO1998015547A1 (en) 1996-10-09 1997-09-24 Thio acid derived monocyclic n-heterocyclics as anticoagulants

Publications (1)

Publication Number Publication Date
IL129056A0 true IL129056A0 (en) 2000-02-17

Family

ID=24938188

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12905697A IL129056A0 (en) 1996-10-09 1997-09-24 Monocyclic N-heterocyclics substituted by thio acid derivatives and pharmaceutical compositions containing same

Country Status (21)

Country Link
US (6) US6004985A (xx)
EP (1) EP0934310B1 (xx)
JP (1) JP3768244B2 (xx)
KR (1) KR20000048966A (xx)
CN (1) CN1111159C (xx)
AT (1) ATE288908T1 (xx)
AU (1) AU730060B2 (xx)
CA (1) CA2268172A1 (xx)
CZ (1) CZ122799A3 (xx)
DE (1) DE69732490T2 (xx)
DK (1) DK0934310T3 (xx)
ES (1) ES2236828T3 (xx)
HK (1) HK1020958A1 (xx)
HU (1) HUP9904180A3 (xx)
IL (1) IL129056A0 (xx)
NO (1) NO991594L (xx)
NZ (1) NZ334758A (xx)
PL (1) PL332602A1 (xx)
PT (1) PT934310E (xx)
SK (1) SK46499A3 (xx)
WO (1) WO1998015547A1 (xx)

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ATE228513T1 (de) 1996-09-12 2002-12-15 Schering Ag Durch cyclische aminosäuren oder cyclische hydroxysäuren substituierte benzamidinderivate und deren verwendung als antikoagulantien
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US6858707B1 (en) 1998-10-05 2005-02-22 Eden Bioscience Corporation Hypersensitive response elicitor fragments which are active but do not elicit a hypersensitive response
US6960705B2 (en) 1998-10-05 2005-11-01 Eden Bioscience Corporation Nucleic acid encoding a hypersensitive response elicitor from Xanthomonas campestris
US6624139B1 (en) 1998-11-05 2003-09-23 Eden Bioscience Corporation Hypersensitive response elicitor-induced stress resistance
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TWI329105B (en) * 2002-02-01 2010-08-21 Rigel Pharmaceuticals Inc 2,4-pyrimidinediamine compounds and their uses
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AR040456A1 (es) 2002-06-27 2005-04-06 Bristol Myers Squibb Co Piridina n-oxidos 2,4 -disubstituidos utiles como inhibidores de transcriptasa inversa del virus de inmunodeficiencia humana
PL216744B1 (pl) * 2002-07-29 2014-05-30 Rigel Pharmaceuticals Zastosowanie związku 2,4-diaminopirymidyny do wytwarzania leku do leczenia lub do zapobiegania chorobom autoimmunizacyjnym
US7419984B2 (en) * 2002-10-17 2008-09-02 Cell Therapeutics, Inc. Pyrimidines and uses thereof
KR20040042071A (ko) * 2002-11-12 2004-05-20 박영민 인터넷 홈페이지를 활용한 경조사 자동알림 및 게시판 자동등록 방법
PT1569912E (pt) 2002-12-03 2015-09-15 Pharmacyclics Llc Derivados 2-(2-hidroxibifenil-3-il)-1h-benzoimidazole-5- carboxamidina como inibidores do fator viia
US6875781B2 (en) 2003-04-04 2005-04-05 Cell Therapeutics, Inc. Pyridines and uses thereof
WO2005012294A1 (en) * 2003-07-30 2005-02-10 Rigel Pharmaceuticals, Inc. 2,4-pyrimidinediamine compounds for use in the treatment or prevention of autoimmune diseases
US7557207B2 (en) 2004-11-24 2009-07-07 Rigel Pharmaceuticals, Inc. Spiro 2,4-pyrimidinediamine compounds and their uses
ES2337496T3 (es) 2005-01-19 2010-04-26 Rigel Pharmaceuticals, Inc. Profarmacos de compuestos de 2,4-pirimidindiamina y sus usos.
JP2008540436A (ja) * 2005-05-03 2008-11-20 ライジェル ファーマシューティカルズ， インコーポレイテッド Ｊａｋキナーゼインヒビターおよびそれらの使用
US20070015834A1 (en) * 2005-07-18 2007-01-18 Moshe Flashner-Barak Formulations of fenofibrate containing PEG/Poloxamer
PT2323993E (pt) 2008-04-16 2015-10-12 Portola Pharm Inc 2,6-diamino-pirimidina-5-il-carboxamidas como inibidores de quinasses syk ou jak
US8138339B2 (en) 2008-04-16 2012-03-20 Portola Pharmaceuticals, Inc. Inhibitors of protein kinases
US9273077B2 (en) 2008-05-21 2016-03-01 Ariad Pharmaceuticals, Inc. Phosphorus derivatives as kinase inhibitors
EA029131B1 (ru) 2008-05-21 2018-02-28 Ариад Фармасьютикалз, Инк. Фосфорсодержащие производные в качестве ингибиторов киназы
BR112013027734A2 (pt) 2011-05-04 2017-08-08 Ariad Pharma Inc compostos para a inibição de proliferação celular em cânceres impulsionados pelo egfr, método e composição farmacêutica
MX363551B (es) 2011-11-23 2019-03-27 Portola Pharmaceuticals Inc Star Compuestos derivados de pirazina como inhibidores de cinasa.
AU2013204563B2 (en) 2012-05-05 2016-05-19 Takeda Pharmaceutical Company Limited Compounds for inhibiting cell proliferation in EGFR-driven cancers
US9611283B1 (en) 2013-04-10 2017-04-04 Ariad Pharmaceuticals, Inc. Methods for inhibiting cell proliferation in ALK-driven cancers
US10676436B2 (en) 2018-07-05 2020-06-09 Landos Biopharma, Inc. NLRX1 ligands
US10487057B1 (en) * 2018-07-05 2019-11-26 Landos Biopharma, Inc. NLRX1 ligands
CN113527193B (zh) * 2020-04-18 2022-06-10 中国科学院精密测量科学与技术创新研究院 一种用于核磁氟谱检测的探针及其在检测巯基类化合物中的应用

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AU675981B2 (en) * 1992-12-02 1997-02-27 Bristol-Myers Squibb Company Guanidinyl-substituted heterocyclic thrombin inhibitors
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US5332822A (en) * 1992-12-24 1994-07-26 Bristol-Myers Squibb Company Heteroaromatic and thioheteroaromatic substituted sulfonamide thrombin inhibitors
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IL115420A0 (en) * 1994-09-26 1995-12-31 Zeneca Ltd Aminoheterocyclic derivatives
ATE251141T1 (de) * 1995-03-10 2003-10-15 Berlex Lab Benzamidin-derivate, deren herstellung und deren verwendung als anti-koagulantien
US5691364A (en) * 1995-03-10 1997-11-25 Berlex Laboratories, Inc. Benzamidine derivatives and their use as anti-coagulants
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ATE228513T1 (de) * 1996-09-12 2002-12-15 Schering Ag Durch cyclische aminosäuren oder cyclische hydroxysäuren substituierte benzamidinderivate und deren verwendung als antikoagulantien
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US6004985A (en) * 1996-10-09 1999-12-21 Berlex Laboratories, Inc. Thio acid derived monocylic N-heterocyclics as anticoagulants
PL341044A1 (en) * 1997-12-19 2001-03-26 Schering Ag Derivatives of orthoantranilic amide as anticoagulants

Also Published As

Publication number Publication date
CZ122799A3 (cs) 1999-09-15
CA2268172A1 (en) 1998-04-16
ES2236828T3 (es) 2005-07-16
US6004985A (en) 1999-12-21
DE69732490D1 (en) 2005-03-17
CN1233247A (zh) 1999-10-27
ATE288908T1 (de) 2005-02-15
DK0934310T3 (da) 2005-05-30
CN1111159C (zh) 2003-06-11
US6166014A (en) 2000-12-26
WO1998015547A1 (en) 1998-04-16
DE69732490T2 (de) 2006-04-27
HUP9904180A2 (hu) 2000-09-28
KR20000048966A (ko) 2000-07-25
AU730060B2 (en) 2001-02-22
NO991594L (no) 1999-06-08
SK46499A3 (en) 2000-04-10
HUP9904180A3 (en) 2000-11-28
US6221886B1 (en) 2001-04-24
NO991594D0 (no) 1999-03-31
PT934310E (pt) 2005-06-30
US6162807A (en) 2000-12-19
US6150382A (en) 2000-11-21
EP0934310A1 (en) 1999-08-11
JP3768244B2 (ja) 2006-04-19
EP0934310B1 (en) 2005-02-09
AU4624097A (en) 1998-05-05
NZ334758A (en) 2000-11-24
JP2001501632A (ja) 2001-02-06
US6034084A (en) 2000-03-07
PL332602A1 (en) 1999-09-27
HK1020958A1 (en) 2004-03-19

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