PT934310E - N-heterociclicos monociclicos substituidos por tioacido uteis como anti-coagulantes - Google Patents

N-heterociclicos monociclicos substituidos por tioacido uteis como anti-coagulantes

Info

Publication number
PT934310E
PT934310E PT97944891T PT97944891T PT934310E PT 934310 E PT934310 E PT 934310E PT 97944891 T PT97944891 T PT 97944891T PT 97944891 T PT97944891 T PT 97944891T PT 934310 E PT934310 E PT 934310E
Authority
PT
Portugal
Prior art keywords
coagulants
ustious
thioacides
neto
hydrochloride
Prior art date
Application number
PT97944891T
Other languages
English (en)
Inventor
Howard P Ng
Monica J Kochanny
Michael M Morrissey
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of PT934310E publication Critical patent/PT934310E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
PT97944891T 1996-10-09 1997-09-24 N-heterociclicos monociclicos substituidos por tioacido uteis como anti-coagulantes PT934310E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/731,128 US6004985A (en) 1996-10-09 1996-10-09 Thio acid derived monocylic N-heterocyclics as anticoagulants

Publications (1)

Publication Number Publication Date
PT934310E true PT934310E (pt) 2005-06-30

Family

ID=24938188

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97944891T PT934310E (pt) 1996-10-09 1997-09-24 N-heterociclicos monociclicos substituidos por tioacido uteis como anti-coagulantes

Country Status (21)

Country Link
US (6) US6004985A (pt)
EP (1) EP0934310B1 (pt)
JP (1) JP3768244B2 (pt)
KR (1) KR20000048966A (pt)
CN (1) CN1111159C (pt)
AT (1) ATE288908T1 (pt)
AU (1) AU730060B2 (pt)
CA (1) CA2268172A1 (pt)
CZ (1) CZ122799A3 (pt)
DE (1) DE69732490T2 (pt)
DK (1) DK0934310T3 (pt)
ES (1) ES2236828T3 (pt)
HK (1) HK1020958A1 (pt)
HU (1) HUP9904180A3 (pt)
IL (1) IL129056A0 (pt)
NO (1) NO991594L (pt)
NZ (1) NZ334758A (pt)
PL (1) PL332602A1 (pt)
PT (1) PT934310E (pt)
SK (1) SK46499A3 (pt)
WO (1) WO1998015547A1 (pt)

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US7419984B2 (en) * 2002-10-17 2008-09-02 Cell Therapeutics, Inc. Pyrimidines and uses thereof
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PT1569912E (pt) 2002-12-03 2015-09-15 Pharmacyclics Llc Derivados 2-(2-hidroxibifenil-3-il)-1h-benzoimidazole-5- carboxamidina como inibidores do fator viia
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NZ545270A (en) * 2003-07-30 2010-04-30 Rigel Pharmaceuticals Inc 2,4-Pyrimidinediamine compounds for use in the treatment or prevention of autoimmune diseases
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EP2161275A1 (en) 2005-01-19 2010-03-10 Rigel Pharmaceuticals, Inc. Prodrugs of 2,4-pyrimidinediamine compounds and their uses
US20060270694A1 (en) * 2005-05-03 2006-11-30 Rigel Pharmaceuticals, Inc. JAK kinase inhibitors and their uses
US20070015834A1 (en) * 2005-07-18 2007-01-18 Moshe Flashner-Barak Formulations of fenofibrate containing PEG/Poloxamer
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NZ589315A (en) 2008-04-16 2012-11-30 Portola Pharm Inc 2,6-diamino-pyrimidin-5-yl-carboxamides as Spleen tryosine kinase (syk) or Janus kinase (JAK) inhibitors
EP2300013B1 (en) 2008-05-21 2017-09-06 Ariad Pharmaceuticals, Inc. Phosphorous derivatives as kinase inhibitors
US9273077B2 (en) 2008-05-21 2016-03-01 Ariad Pharmaceuticals, Inc. Phosphorus derivatives as kinase inhibitors
JP5999177B2 (ja) 2011-05-04 2016-09-28 アリアド・ファーマシューティカルズ・インコーポレイテッド Ｅｇｆｒ発動性がんの細胞増殖阻害用化合物
IN2014CN04065A (pt) 2011-11-23 2015-09-04 Portola Pharm Inc
US20150166591A1 (en) 2012-05-05 2015-06-18 Ariad Pharmaceuticals, Inc. Methods and compositions for raf kinase mediated diseases
US9611283B1 (en) 2013-04-10 2017-04-04 Ariad Pharmaceuticals, Inc. Methods for inhibiting cell proliferation in ALK-driven cancers
US10487057B1 (en) * 2018-07-05 2019-11-26 Landos Biopharma, Inc. NLRX1 ligands
US10676436B2 (en) * 2018-07-05 2020-06-09 Landos Biopharma, Inc. NLRX1 ligands
CN113527193B (zh) * 2020-04-18 2022-06-10 中国科学院精密测量科学与技术创新研究院 一种用于核磁氟谱检测的探针及其在检测巯基类化合物中的应用

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CA2315070A1 (en) 1997-12-17 1999-07-01 Schering Aktiengesellschaft Ortho-anthranilamide derivatives as anti-coagulants

Also Published As

Publication number Publication date
US6162807A (en) 2000-12-19
JP2001501632A (ja) 2001-02-06
AU4624097A (en) 1998-05-05
US6004985A (en) 1999-12-21
US6221886B1 (en) 2001-04-24
ATE288908T1 (de) 2005-02-15
HUP9904180A3 (en) 2000-11-28
HK1020958A1 (en) 2004-03-19
KR20000048966A (ko) 2000-07-25
CN1111159C (zh) 2003-06-11
CZ122799A3 (cs) 1999-09-15
US6034084A (en) 2000-03-07
SK46499A3 (en) 2000-04-10
US6166014A (en) 2000-12-26
ES2236828T3 (es) 2005-07-16
WO1998015547A1 (en) 1998-04-16
EP0934310A1 (en) 1999-08-11
DE69732490D1 (en) 2005-03-17
PL332602A1 (en) 1999-09-27
CA2268172A1 (en) 1998-04-16
NO991594D0 (no) 1999-03-31
DE69732490T2 (de) 2006-04-27
US6150382A (en) 2000-11-21
DK0934310T3 (da) 2005-05-30
AU730060B2 (en) 2001-02-22
NO991594L (no) 1999-06-08
HUP9904180A2 (hu) 2000-09-28
NZ334758A (en) 2000-11-24
IL129056A0 (en) 2000-02-17
CN1233247A (zh) 1999-10-27
JP3768244B2 (ja) 2006-04-19
EP0934310B1 (en) 2005-02-09

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