MX9403915A - Derivados de n-alquiltio de pliamina como agentes radioprotectores. - Google Patents
Derivados de n-alquiltio de pliamina como agentes radioprotectores.Info
- Publication number
- MX9403915A MX9403915A MX9403915A MX9403915A MX9403915A MX 9403915 A MX9403915 A MX 9403915A MX 9403915 A MX9403915 A MX 9403915A MX 9403915 A MX9403915 A MX 9403915A MX 9403915 A MX9403915 A MX 9403915A
- Authority
- MX
- Mexico
- Prior art keywords
- plyamine
- alkyltium
- derivatives
- radio
- protective agents
- Prior art date
Links
- 239000000718 radiation-protective agent Substances 0.000 title abstract 2
- 229920000768 polyamine Polymers 0.000 abstract 1
- 150000003573 thiols Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/25—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/16—Esters of thiophosphoric acids or thiophosphorous acids
- C07F9/165—Esters of thiophosphoric acids
- C07F9/1651—Esters of thiophosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Polyamides (AREA)
- Steroid Compounds (AREA)
Abstract
La presente invención se relaciona con ciertos poliaminatioles los cualesson útiles como agentes radioprotectores.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6930293A | 1993-05-26 | 1993-05-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9403915A true MX9403915A (es) | 1995-01-31 |
Family
ID=22088062
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9403915A MX9403915A (es) | 1993-05-26 | 1994-05-25 | Derivados de n-alquiltio de pliamina como agentes radioprotectores. |
Country Status (19)
Country | Link |
---|---|
US (1) | US5434145A (es) |
EP (1) | EP0700380B1 (es) |
KR (1) | KR960702830A (es) |
CN (1) | CN1124483A (es) |
AT (1) | ATE167670T1 (es) |
AU (1) | AU679236B2 (es) |
CA (1) | CA2161869C (es) |
DE (1) | DE69411271T2 (es) |
DK (1) | DK0700380T3 (es) |
ES (1) | ES2119203T3 (es) |
FI (1) | FI955643A0 (es) |
GR (1) | GR3027657T3 (es) |
HU (1) | HUT73421A (es) |
IL (1) | IL109720A (es) |
MX (1) | MX9403915A (es) |
NO (1) | NO306020B1 (es) |
NZ (1) | NZ267211A (es) |
WO (1) | WO1994027961A1 (es) |
ZA (1) | ZA943520B (es) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5342945A (en) * | 1986-12-02 | 1994-08-30 | University Of Florida Research Foundation, Inc. | Anti-neoplastic, anti-viral or anti-retroviral spermine derivatives |
US5393757A (en) * | 1986-12-02 | 1995-02-28 | University Of Florida | Polyamines and anti-diarrheal and gastrointestinal anti-spasmodic pharmaceutical compositions and methods of treatment |
US5677351A (en) * | 1986-12-02 | 1997-10-14 | University Of Florida Research Foundation, Inc. | Sterically hindered tetraamines and method for their production |
US5869338A (en) * | 1992-03-13 | 1999-02-09 | Arch Development Corporation | Method for protection against genotoxic mutagenesis |
US5567686A (en) * | 1992-03-13 | 1996-10-22 | Arch Development Corporation | Method for protection against genotoxic mutagenesis |
US5994409A (en) * | 1997-12-09 | 1999-11-30 | U.S. Bioscience, Inc. | Methods for treatment of neuro--and nephro--disorders and therapeutic toxicities using aminothiol compounds |
WO2000036667A2 (en) * | 1998-12-15 | 2000-06-22 | Duracell Inc. | Electrochemical cell closure |
US6649587B1 (en) | 1999-04-30 | 2003-11-18 | Slil Biomedical Corporation | Polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases |
EP1698629A3 (en) * | 1999-04-30 | 2006-11-29 | Cellgate, Inc. | Polyamines and their use in therapy |
US6482943B1 (en) * | 1999-04-30 | 2002-11-19 | Slil Biomedical Corporation | Quinones as disease therapies |
US7312244B2 (en) * | 1999-04-30 | 2007-12-25 | Cellgate, Inc. | Polyamine analog-amino acid conjugates useful as anticancer agents |
IL146126A0 (en) * | 1999-04-30 | 2002-07-25 | Slil Biomedical Corp | Novel polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases |
US6489312B1 (en) * | 1999-06-15 | 2002-12-03 | Medimmune Oncology, Inc. | Pharmaceutical formulations comprising aminoalkyl phosphorothioates |
US6160022A (en) * | 1999-07-19 | 2000-12-12 | University Of Florida | Chemical resection of pancreas |
US7053072B2 (en) * | 2001-05-11 | 2006-05-30 | Medimmune Oncology, Inc. | Methods for the administration of amifostine and related compounds |
US7045550B2 (en) * | 2001-08-07 | 2006-05-16 | Wisconsin Alumni Research Foundation | Polyamines and analogs for protecting cells during cancer chemotherapy and radiotherapy |
JP2005511734A (ja) * | 2001-12-07 | 2005-04-28 | スリル バイオメディカル コーポレイション | 癌治療用のシクロアルキル置換ポリアミンおよびそれらの合成方法 |
US20050027016A1 (en) * | 2002-02-07 | 2005-02-03 | Fahl Kathleen L | Polyamine compounds and compositions for use in conjection with cancer therapy |
WO2005014524A2 (en) * | 2003-08-07 | 2005-02-17 | Wisconsin Alumni Research Foundation | Amino thiol compounds and compositions for use in conjunction with cancer therapy |
US7754463B2 (en) * | 2006-06-20 | 2010-07-13 | Dana-Farber Cancer Institute | Inhibitors of USP1 Deubiquitinating Enzyme Complex |
US20100049284A1 (en) * | 2008-05-15 | 2010-02-25 | The Catholic University Of America | Use of heat to treat biological systems exposed to damaging radiation |
CA2797719C (en) | 2010-04-30 | 2019-11-26 | Dana-Farber Cancer Institute, Inc. | Small molecule inhibitors of usp1 deubiquitinating enzyme activity |
US9725425B1 (en) | 2014-02-25 | 2017-08-08 | Dana-Farber Cancer Institute, Inc. | Compounds and methods for treating cancer |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2653977A (en) * | 1953-09-29 | Chxnx | ||
US2951092A (en) * | 1956-12-13 | 1960-08-30 | Olin Mathieson | Triamine derivatives |
US3892824A (en) * | 1968-12-16 | 1975-07-01 | Southern Res Inst | S-{107 -({107 -aminoalkylamino)alkyl dihydrogen phosphorothioates |
US5342945A (en) * | 1986-12-02 | 1994-08-30 | University Of Florida Research Foundation, Inc. | Anti-neoplastic, anti-viral or anti-retroviral spermine derivatives |
US5091576A (en) * | 1986-12-02 | 1992-02-25 | University Of Florida | Anti-neoplastic, anti-viral or anti-retroviral spermine derivatives |
US5109024A (en) * | 1987-02-03 | 1992-04-28 | Merrell Dow Pharmaceuticals Inc. | Polyamine derivatives as antineoplastic agents |
US5217964A (en) * | 1991-01-23 | 1993-06-08 | Merrell Dow Pharmaceuticals Inc. | Polyamine thiols as radioprotective agents |
US5488042A (en) * | 1992-03-13 | 1996-01-30 | Arch Development Corporation | Method for protection against genotoxic mutagenesis |
-
1994
- 1994-04-28 AT AT94917900T patent/ATE167670T1/de not_active IP Right Cessation
- 1994-04-28 ES ES94917900T patent/ES2119203T3/es not_active Expired - Lifetime
- 1994-04-28 NZ NZ267211A patent/NZ267211A/en unknown
- 1994-04-28 HU HU9503370A patent/HUT73421A/hu unknown
- 1994-04-28 WO PCT/US1994/004662 patent/WO1994027961A1/en active IP Right Grant
- 1994-04-28 DE DE69411271T patent/DE69411271T2/de not_active Expired - Fee Related
- 1994-04-28 CN CN94192245A patent/CN1124483A/zh active Pending
- 1994-04-28 CA CA002161869A patent/CA2161869C/en not_active Expired - Fee Related
- 1994-04-28 EP EP94917900A patent/EP0700380B1/en not_active Expired - Lifetime
- 1994-04-28 DK DK94917900T patent/DK0700380T3/da active
- 1994-04-28 AU AU69428/94A patent/AU679236B2/en not_active Ceased
- 1994-05-20 ZA ZA943520A patent/ZA943520B/xx unknown
- 1994-05-22 IL IL10972094A patent/IL109720A/xx not_active IP Right Cessation
- 1994-05-25 MX MX9403915A patent/MX9403915A/es not_active IP Right Cessation
- 1994-10-14 US US08/323,472 patent/US5434145A/en not_active Expired - Fee Related
-
1995
- 1995-11-23 FI FI955643A patent/FI955643A0/fi unknown
- 1995-11-24 NO NO954768A patent/NO306020B1/no unknown
- 1995-11-25 KR KR1019950705352A patent/KR960702830A/ko not_active Application Discontinuation
-
1998
- 1998-08-14 GR GR980401833T patent/GR3027657T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
KR960702830A (ko) | 1996-05-23 |
CA2161869C (en) | 2001-11-13 |
FI955643A (fi) | 1995-11-23 |
CA2161869A1 (en) | 1994-12-08 |
IL109720A0 (en) | 1994-08-26 |
US5434145A (en) | 1995-07-18 |
GR3027657T3 (en) | 1998-11-30 |
EP0700380B1 (en) | 1998-06-24 |
WO1994027961A1 (en) | 1994-12-08 |
CN1124483A (zh) | 1996-06-12 |
ZA943520B (en) | 1995-01-23 |
NO306020B1 (no) | 1999-09-06 |
FI955643A0 (fi) | 1995-11-23 |
ES2119203T3 (es) | 1998-10-01 |
IL109720A (en) | 1999-09-22 |
AU6942894A (en) | 1994-12-20 |
HUT73421A (en) | 1996-07-29 |
NO954768L (no) | 1996-01-23 |
AU679236B2 (en) | 1997-06-26 |
NZ267211A (en) | 1997-11-24 |
HU9503370D0 (en) | 1996-01-29 |
DE69411271D1 (de) | 1998-07-30 |
EP0700380A1 (en) | 1996-03-13 |
NO954768D0 (no) | 1995-11-24 |
DK0700380T3 (da) | 1998-11-09 |
DE69411271T2 (de) | 1998-11-05 |
ATE167670T1 (de) | 1998-07-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration | ||
MM | Annulment or lapse due to non-payment of fees |