NO960849L - Difluorstaton-antivirale analoger - Google Patents
Difluorstaton-antivirale analogerInfo
- Publication number
- NO960849L NO960849L NO960849A NO960849A NO960849L NO 960849 L NO960849 L NO 960849L NO 960849 A NO960849 A NO 960849A NO 960849 A NO960849 A NO 960849A NO 960849 L NO960849 L NO 960849L
- Authority
- NO
- Norway
- Prior art keywords
- difluorostatone
- antiviral
- analogs
- antiviral analogs
- statone
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/56—Amides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pyridine Compounds (AREA)
- Medicinal Preparation (AREA)
- Epoxy Compounds (AREA)
Abstract
Oppfinnelsen angår nye staton-aritivirale analoger, fremgangs- måter og mellomprodukter som er anvend- bare for deres fremstilling og deres anvendelse som antivirale midler.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP93402194 | 1993-09-09 | ||
PCT/US1994/009053 WO1995007257A1 (en) | 1993-09-09 | 1994-08-10 | Difluoro statone antiviral analogs |
Publications (2)
Publication Number | Publication Date |
---|---|
NO960849L true NO960849L (no) | 1996-03-01 |
NO960849D0 NO960849D0 (no) | 1996-03-01 |
Family
ID=8214747
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO960849A NO960849D0 (no) | 1993-09-09 | 1996-03-01 | Difluorstaton-antivirale analoger |
Country Status (20)
Country | Link |
---|---|
US (2) | US5831094A (no) |
EP (1) | EP0717731B1 (no) |
JP (1) | JPH09502437A (no) |
KR (1) | KR100308839B1 (no) |
CN (1) | CN1130898A (no) |
AT (1) | ATE179167T1 (no) |
AU (1) | AU683927B2 (no) |
CA (1) | CA2170607C (no) |
DE (1) | DE69418050T2 (no) |
DK (1) | DK0717731T3 (no) |
ES (1) | ES2133573T3 (no) |
FI (1) | FI961105A0 (no) |
GR (1) | GR3030352T3 (no) |
HU (1) | HUT74569A (no) |
IL (1) | IL110865A (no) |
NO (1) | NO960849D0 (no) |
NZ (1) | NZ271825A (no) |
TW (1) | TW282449B (no) |
WO (1) | WO1995007257A1 (no) |
ZA (1) | ZA946815B (no) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR9610422A (pt) * | 1995-08-30 | 1999-07-13 | Searle & Co | Derivados de meta-guanidina uréia tiouréia ou ácido aminobenzóico azacíclico como antagonistas de integrina |
WO2000044770A1 (fr) * | 1999-01-28 | 2000-08-03 | Chugai Seiyaku Kabushiki Kaisha | Derives phenethylamine substitues |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH672792A5 (no) * | 1985-02-19 | 1989-12-29 | Sandoz Ag | |
US5066643A (en) * | 1985-02-19 | 1991-11-19 | Sandoz Ltd. | Fluorine and chlorine statine or statone containing peptides and method of use |
DE3674131D1 (de) * | 1985-04-19 | 1990-10-18 | Upjohn Co | Substituierte dihalo-statin-reninhemmungsmittel. |
GB8619182D0 (en) * | 1986-08-06 | 1986-09-17 | Sandoz Ltd | Peptides & derivatives |
NZ223148A (en) * | 1987-01-16 | 1989-10-27 | Merrell Dow Pharma | Peptide derivatives having peptidase inhibition activity |
BE1002213A5 (fr) * | 1987-04-23 | 1990-10-16 | Sandoz Sa | Nouveaux derives peptidiques, leur preparation et leur utilisation comme medicaments. |
FR2624513A1 (fr) * | 1987-12-15 | 1989-06-16 | Sandoz Sa | Peptides contenant du silicium, leur preparation et leur utilisation comme medicaments |
IL90872A0 (en) * | 1988-07-08 | 1990-02-09 | Smithkline Beckman Corp | Retroviral protease binding peptides |
WO1990000399A1 (en) * | 1988-07-08 | 1990-01-25 | Smithkline Beckman Corporation | Retroviral protease binding peptides |
CA2010531A1 (en) * | 1989-03-06 | 1990-09-06 | Werner Neidhart | Amino acid derivatives |
US5151438A (en) * | 1989-05-23 | 1992-09-29 | Abbott Laboratories | Retroviral protease inhibiting compounds |
CA2098020C (en) * | 1991-01-02 | 2003-10-21 | Daniel Schirlin | Anti-viral compounds |
KR100220876B1 (ko) * | 1991-01-02 | 1999-10-01 | 슈테펜엘.네스비트 | 항 바이러스 화합물 |
WO1993019059A1 (en) * | 1992-03-25 | 1993-09-30 | Pfizer Limited | Antiviral peptides |
GB9210744D0 (en) * | 1992-05-20 | 1992-07-08 | Pfizer Ltd | Antiviral peptides |
CA2136312A1 (en) * | 1992-05-21 | 1993-11-25 | Michael Clare | Retroviral protease inhibitors |
KR100316864B1 (ko) * | 1993-07-08 | 2002-11-13 | 메렐 파마슈티칼스 인크. | 디플루오로스타톤동족체 |
CN1152910A (zh) * | 1994-07-15 | 1997-06-25 | 默里尔药物公司 | 二氟斯塔酮抗病毒剂 |
-
1994
- 1994-08-10 KR KR1019960701172A patent/KR100308839B1/ko not_active IP Right Cessation
- 1994-08-10 EP EP94925816A patent/EP0717731B1/en not_active Expired - Lifetime
- 1994-08-10 DK DK94925816T patent/DK0717731T3/da active
- 1994-08-10 DE DE69418050T patent/DE69418050T2/de not_active Expired - Fee Related
- 1994-08-10 HU HU9600601A patent/HUT74569A/hu unknown
- 1994-08-10 US US08/596,336 patent/US5831094A/en not_active Expired - Fee Related
- 1994-08-10 AT AT94925816T patent/ATE179167T1/de not_active IP Right Cessation
- 1994-08-10 CN CN94193321A patent/CN1130898A/zh active Pending
- 1994-08-10 JP JP7508667A patent/JPH09502437A/ja not_active Ceased
- 1994-08-10 NZ NZ271825A patent/NZ271825A/en unknown
- 1994-08-10 ES ES94925816T patent/ES2133573T3/es not_active Expired - Lifetime
- 1994-08-10 WO PCT/US1994/009053 patent/WO1995007257A1/en active IP Right Grant
- 1994-08-10 AU AU75606/94A patent/AU683927B2/en not_active Ceased
- 1994-08-10 CA CA002170607A patent/CA2170607C/en not_active Expired - Fee Related
- 1994-09-05 ZA ZA946815A patent/ZA946815B/xx unknown
- 1994-09-05 IL IL11086594A patent/IL110865A/xx not_active IP Right Cessation
- 1994-09-06 TW TW083108216A patent/TW282449B/zh active
-
1996
- 1996-03-01 NO NO960849A patent/NO960849D0/no unknown
- 1996-03-08 FI FI961105A patent/FI961105A0/fi not_active IP Right Cessation
-
1998
- 1998-05-19 US US09/081,307 patent/US5948778A/en not_active Expired - Fee Related
-
1999
- 1999-05-27 GR GR990401441T patent/GR3030352T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
HU9600601D0 (en) | 1996-05-28 |
US5831094A (en) | 1998-11-03 |
AU683927B2 (en) | 1997-11-27 |
US5948778A (en) | 1999-09-07 |
FI961105A (fi) | 1996-03-08 |
HUT74569A (en) | 1997-01-28 |
EP0717731B1 (en) | 1999-04-21 |
ZA946815B (en) | 1995-04-24 |
CN1130898A (zh) | 1996-09-11 |
JPH09502437A (ja) | 1997-03-11 |
KR100308839B1 (ko) | 2002-10-04 |
IL110865A0 (en) | 1994-11-28 |
WO1995007257A1 (en) | 1995-03-16 |
DE69418050T2 (de) | 1999-11-25 |
KR960704838A (ko) | 1996-10-09 |
NZ271825A (en) | 1997-11-24 |
DE69418050D1 (de) | 1999-05-27 |
ATE179167T1 (de) | 1999-05-15 |
DK0717731T3 (da) | 1999-11-01 |
FI961105A0 (fi) | 1996-03-08 |
CA2170607A1 (en) | 1995-03-16 |
IL110865A (en) | 1999-07-14 |
ES2133573T3 (es) | 1999-09-16 |
GR3030352T3 (en) | 1999-09-30 |
NO960849D0 (no) | 1996-03-01 |
AU7560694A (en) | 1995-03-27 |
EP0717731A1 (en) | 1996-06-26 |
TW282449B (no) | 1996-08-01 |
CA2170607C (en) | 2000-02-22 |
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