NO954768L - N-alkyltiopolyaminderivater som radiobeskyttende midler - Google Patents
N-alkyltiopolyaminderivater som radiobeskyttende midlerInfo
- Publication number
- NO954768L NO954768L NO954768A NO954768A NO954768L NO 954768 L NO954768 L NO 954768L NO 954768 A NO954768 A NO 954768A NO 954768 A NO954768 A NO 954768A NO 954768 L NO954768 L NO 954768L
- Authority
- NO
- Norway
- Prior art keywords
- alkylthiopolyamine
- derivatives
- radioprotective agents
- radioprotective
- agents
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/25—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/16—Esters of thiophosphoric acids or thiophosphorous acids
- C07F9/165—Esters of thiophosphoric acids
- C07F9/1651—Esters of thiophosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6930293A | 1993-05-26 | 1993-05-26 | |
PCT/US1994/004662 WO1994027961A1 (en) | 1993-05-26 | 1994-04-28 | N-alkylthio polyamine derivatives as radioprotective agents |
Publications (3)
Publication Number | Publication Date |
---|---|
NO954768D0 NO954768D0 (no) | 1995-11-24 |
NO954768L true NO954768L (no) | 1996-01-23 |
NO306020B1 NO306020B1 (no) | 1999-09-06 |
Family
ID=22088062
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO954768A NO306020B1 (no) | 1993-05-26 | 1995-11-24 | N-alkylthiopolyaminderivater som radiobeskyttende midler |
Country Status (19)
Country | Link |
---|---|
US (1) | US5434145A (no) |
EP (1) | EP0700380B1 (no) |
KR (1) | KR960702830A (no) |
CN (1) | CN1124483A (no) |
AT (1) | ATE167670T1 (no) |
AU (1) | AU679236B2 (no) |
CA (1) | CA2161869C (no) |
DE (1) | DE69411271T2 (no) |
DK (1) | DK0700380T3 (no) |
ES (1) | ES2119203T3 (no) |
FI (1) | FI955643A0 (no) |
GR (1) | GR3027657T3 (no) |
HU (1) | HUT73421A (no) |
IL (1) | IL109720A (no) |
MX (1) | MX9403915A (no) |
NO (1) | NO306020B1 (no) |
NZ (1) | NZ267211A (no) |
WO (1) | WO1994027961A1 (no) |
ZA (1) | ZA943520B (no) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5393757A (en) * | 1986-12-02 | 1995-02-28 | University Of Florida | Polyamines and anti-diarrheal and gastrointestinal anti-spasmodic pharmaceutical compositions and methods of treatment |
US5342945A (en) * | 1986-12-02 | 1994-08-30 | University Of Florida Research Foundation, Inc. | Anti-neoplastic, anti-viral or anti-retroviral spermine derivatives |
US5677351A (en) * | 1986-12-02 | 1997-10-14 | University Of Florida Research Foundation, Inc. | Sterically hindered tetraamines and method for their production |
US5567686A (en) * | 1992-03-13 | 1996-10-22 | Arch Development Corporation | Method for protection against genotoxic mutagenesis |
US5869338A (en) * | 1992-03-13 | 1999-02-09 | Arch Development Corporation | Method for protection against genotoxic mutagenesis |
US5994409A (en) * | 1997-12-09 | 1999-11-30 | U.S. Bioscience, Inc. | Methods for treatment of neuro--and nephro--disorders and therapeutic toxicities using aminothiol compounds |
CN1336015A (zh) * | 1998-12-15 | 2002-02-13 | 杜拉塞尔公司 | 电化学电池封装 |
US6482943B1 (en) * | 1999-04-30 | 2002-11-19 | Slil Biomedical Corporation | Quinones as disease therapies |
US6794545B1 (en) * | 1999-04-30 | 2004-09-21 | Slil Biomedical Corporation | Conformationally restricted polyamine analogs as disease therapies |
CA2368801A1 (en) * | 1999-04-30 | 2000-11-09 | Slil Biomedical Corporation | Conjugates as therapies for cancer and prostate diseases |
US6649587B1 (en) | 1999-04-30 | 2003-11-18 | Slil Biomedical Corporation | Polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases |
US6489312B1 (en) | 1999-06-15 | 2002-12-03 | Medimmune Oncology, Inc. | Pharmaceutical formulations comprising aminoalkyl phosphorothioates |
US6160022A (en) * | 1999-07-19 | 2000-12-12 | University Of Florida | Chemical resection of pancreas |
AU2002235126A1 (en) * | 2000-11-08 | 2002-05-21 | Slil Biomedical Corporation | Novel polyamine analog-amino acid conjugates useful as anticancer agents |
US7053072B2 (en) * | 2001-05-11 | 2006-05-30 | Medimmune Oncology, Inc. | Methods for the administration of amifostine and related compounds |
US7045550B2 (en) * | 2001-08-07 | 2006-05-16 | Wisconsin Alumni Research Foundation | Polyamines and analogs for protecting cells during cancer chemotherapy and radiotherapy |
MXPA04005509A (es) * | 2001-12-07 | 2004-12-06 | Slil Biomedical Corp | Poliaminas sustituidas con cicloalquilo para terapia de cancer y metodos de sintesis de las mismas. |
KR20040091014A (ko) * | 2002-02-07 | 2004-10-27 | 위스콘신 얼럼나이 리서어치 화운데이션 | 항암 요법과 병행해서 사용하기 위한 폴리아민 화합물 및조성물 |
WO2005014524A2 (en) * | 2003-08-07 | 2005-02-17 | Wisconsin Alumni Research Foundation | Amino thiol compounds and compositions for use in conjunction with cancer therapy |
WO2007149484A2 (en) * | 2006-06-20 | 2007-12-27 | Dana-Farber Cancer Institute | Inhibitors of usp1 deubiquitinating enzyme complex |
US20100049284A1 (en) * | 2008-05-15 | 2010-02-25 | The Catholic University Of America | Use of heat to treat biological systems exposed to damaging radiation |
CA2797719C (en) | 2010-04-30 | 2019-11-26 | Dana-Farber Cancer Institute, Inc. | Small molecule inhibitors of usp1 deubiquitinating enzyme activity |
US9725425B1 (en) | 2014-02-25 | 2017-08-08 | Dana-Farber Cancer Institute, Inc. | Compounds and methods for treating cancer |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2653977A (en) * | 1953-09-29 | Chxnx | ||
US2951092A (en) * | 1956-12-13 | 1960-08-30 | Olin Mathieson | Triamine derivatives |
US3892824A (en) * | 1968-12-16 | 1975-07-01 | Southern Res Inst | S-{107 -({107 -aminoalkylamino)alkyl dihydrogen phosphorothioates |
US5342945A (en) * | 1986-12-02 | 1994-08-30 | University Of Florida Research Foundation, Inc. | Anti-neoplastic, anti-viral or anti-retroviral spermine derivatives |
US5091576A (en) * | 1986-12-02 | 1992-02-25 | University Of Florida | Anti-neoplastic, anti-viral or anti-retroviral spermine derivatives |
US5109024A (en) * | 1987-02-03 | 1992-04-28 | Merrell Dow Pharmaceuticals Inc. | Polyamine derivatives as antineoplastic agents |
US5217964A (en) * | 1991-01-23 | 1993-06-08 | Merrell Dow Pharmaceuticals Inc. | Polyamine thiols as radioprotective agents |
US5488042A (en) * | 1992-03-13 | 1996-01-30 | Arch Development Corporation | Method for protection against genotoxic mutagenesis |
-
1994
- 1994-04-28 DE DE69411271T patent/DE69411271T2/de not_active Expired - Fee Related
- 1994-04-28 AT AT94917900T patent/ATE167670T1/de not_active IP Right Cessation
- 1994-04-28 DK DK94917900T patent/DK0700380T3/da active
- 1994-04-28 WO PCT/US1994/004662 patent/WO1994027961A1/en active IP Right Grant
- 1994-04-28 EP EP94917900A patent/EP0700380B1/en not_active Expired - Lifetime
- 1994-04-28 HU HU9503370A patent/HUT73421A/hu unknown
- 1994-04-28 ES ES94917900T patent/ES2119203T3/es not_active Expired - Lifetime
- 1994-04-28 CN CN94192245A patent/CN1124483A/zh active Pending
- 1994-04-28 NZ NZ267211A patent/NZ267211A/en unknown
- 1994-04-28 AU AU69428/94A patent/AU679236B2/en not_active Ceased
- 1994-04-28 CA CA002161869A patent/CA2161869C/en not_active Expired - Fee Related
- 1994-05-20 ZA ZA943520A patent/ZA943520B/xx unknown
- 1994-05-22 IL IL10972094A patent/IL109720A/xx not_active IP Right Cessation
- 1994-05-25 MX MX9403915A patent/MX9403915A/es not_active IP Right Cessation
- 1994-10-14 US US08/323,472 patent/US5434145A/en not_active Expired - Fee Related
-
1995
- 1995-11-23 FI FI955643A patent/FI955643A0/fi unknown
- 1995-11-24 NO NO954768A patent/NO306020B1/no unknown
- 1995-11-25 KR KR1019950705352A patent/KR960702830A/ko not_active Application Discontinuation
-
1998
- 1998-08-14 GR GR980401833T patent/GR3027657T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
CN1124483A (zh) | 1996-06-12 |
ES2119203T3 (es) | 1998-10-01 |
ATE167670T1 (de) | 1998-07-15 |
MX9403915A (es) | 1995-01-31 |
ZA943520B (en) | 1995-01-23 |
IL109720A0 (en) | 1994-08-26 |
KR960702830A (ko) | 1996-05-23 |
NZ267211A (en) | 1997-11-24 |
NO306020B1 (no) | 1999-09-06 |
FI955643A (fi) | 1995-11-23 |
FI955643A0 (fi) | 1995-11-23 |
DK0700380T3 (da) | 1998-11-09 |
AU6942894A (en) | 1994-12-20 |
DE69411271D1 (de) | 1998-07-30 |
GR3027657T3 (en) | 1998-11-30 |
NO954768D0 (no) | 1995-11-24 |
WO1994027961A1 (en) | 1994-12-08 |
EP0700380B1 (en) | 1998-06-24 |
EP0700380A1 (en) | 1996-03-13 |
AU679236B2 (en) | 1997-06-26 |
CA2161869A1 (en) | 1994-12-08 |
CA2161869C (en) | 2001-11-13 |
HUT73421A (en) | 1996-07-29 |
US5434145A (en) | 1995-07-18 |
DE69411271T2 (de) | 1998-11-05 |
IL109720A (en) | 1999-09-22 |
HU9503370D0 (en) | 1996-01-29 |
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