NO991594D0 - Tiosyreavledede monosykliske N-heterosykluser som antikoagulanter - Google Patents

Tiosyreavledede monosykliske N-heterosykluser som antikoagulanter

Info

Publication number
NO991594D0
NO991594D0 NO991594A NO991594A NO991594D0 NO 991594 D0 NO991594 D0 NO 991594D0 NO 991594 A NO991594 A NO 991594A NO 991594 A NO991594 A NO 991594A NO 991594 D0 NO991594 D0 NO 991594D0
Authority
NO
Norway
Prior art keywords
thioacid
anticoagulants
heterocycles
monocyclic
derived
Prior art date
Application number
NO991594A
Other languages
English (en)
Other versions
NO991594L (no
Inventor
Monica J Kochanny
Michael M Morrissey
Howard P Ng
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of NO991594D0 publication Critical patent/NO991594D0/no
Publication of NO991594L publication Critical patent/NO991594L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO991594A 1996-10-09 1999-03-31 Tiosyreavledede, monosykliske N-heterosykluser som antikoagulanter NO991594L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/731,128 US6004985A (en) 1996-10-09 1996-10-09 Thio acid derived monocylic N-heterocyclics as anticoagulants
PCT/EP1997/005231 WO1998015547A1 (en) 1996-10-09 1997-09-24 Thio acid derived monocyclic n-heterocyclics as anticoagulants

Publications (2)

Publication Number Publication Date
NO991594D0 true NO991594D0 (no) 1999-03-31
NO991594L NO991594L (no) 1999-06-08

Family

ID=24938188

Family Applications (1)

Application Number Title Priority Date Filing Date
NO991594A NO991594L (no) 1996-10-09 1999-03-31 Tiosyreavledede, monosykliske N-heterosykluser som antikoagulanter

Country Status (21)

Country Link
US (6) US6004985A (no)
EP (1) EP0934310B1 (no)
JP (1) JP3768244B2 (no)
KR (1) KR20000048966A (no)
CN (1) CN1111159C (no)
AT (1) ATE288908T1 (no)
AU (1) AU730060B2 (no)
CA (1) CA2268172A1 (no)
CZ (1) CZ122799A3 (no)
DE (1) DE69732490T2 (no)
DK (1) DK0934310T3 (no)
ES (1) ES2236828T3 (no)
HK (1) HK1020958A1 (no)
HU (1) HUP9904180A3 (no)
IL (1) IL129056A0 (no)
NO (1) NO991594L (no)
NZ (1) NZ334758A (no)
PL (1) PL332602A1 (no)
PT (1) PT934310E (no)
SK (1) SK46499A3 (no)
WO (1) WO1998015547A1 (no)

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US8178671B2 (en) * 2003-07-30 2012-05-15 Rigel Pharmaceuticals, Inc. Methods of treating or preventing autoimmune diseases with 2, 4-pyrimidinediamine compounds
ATE540035T1 (de) * 2004-11-24 2012-01-15 Rigel Pharmaceuticals Inc Spiro-2,4-pyrimidindiamin-verbindungen und ihre verwendungen
DK1856135T3 (da) 2005-01-19 2010-04-12 Rigel Pharmaceuticals Inc Prodrugs af 2,4-pyrimidindiamin-forbindelser og deres anvendelser
US20060270694A1 (en) * 2005-05-03 2006-11-30 Rigel Pharmaceuticals, Inc. JAK kinase inhibitors and their uses
US20070015834A1 (en) * 2005-07-18 2007-01-18 Moshe Flashner-Barak Formulations of fenofibrate containing PEG/Poloxamer
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US8138339B2 (en) 2008-04-16 2012-03-20 Portola Pharmaceuticals, Inc. Inhibitors of protein kinases
PT2300013T (pt) 2008-05-21 2017-10-31 Ariad Pharma Inc Derivados de fósforo como inibidores de cinases
US9273077B2 (en) 2008-05-21 2016-03-01 Ariad Pharmaceuticals, Inc. Phosphorus derivatives as kinase inhibitors
BR112013027734A2 (pt) 2011-05-04 2017-08-08 Ariad Pharma Inc compostos para a inibição de proliferação celular em cânceres impulsionados pelo egfr, método e composição farmacêutica
US8877760B2 (en) 2011-11-23 2014-11-04 Portola Pharmaceuticals, Inc. Substituted pyrazine-2-carboxamide kinase inhibitors
US20150166591A1 (en) 2012-05-05 2015-06-18 Ariad Pharmaceuticals, Inc. Methods and compositions for raf kinase mediated diseases
US9611283B1 (en) 2013-04-10 2017-04-04 Ariad Pharmaceuticals, Inc. Methods for inhibiting cell proliferation in ALK-driven cancers
US10676436B2 (en) 2018-07-05 2020-06-09 Landos Biopharma, Inc. NLRX1 ligands
US10487057B1 (en) * 2018-07-05 2019-11-26 Landos Biopharma, Inc. NLRX1 ligands
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Also Published As

Publication number Publication date
DE69732490T2 (de) 2006-04-27
JP3768244B2 (ja) 2006-04-19
PT934310E (pt) 2005-06-30
PL332602A1 (en) 1999-09-27
CA2268172A1 (en) 1998-04-16
HUP9904180A2 (hu) 2000-09-28
US6162807A (en) 2000-12-19
AU730060B2 (en) 2001-02-22
US6034084A (en) 2000-03-07
ES2236828T3 (es) 2005-07-16
EP0934310A1 (en) 1999-08-11
SK46499A3 (en) 2000-04-10
WO1998015547A1 (en) 1998-04-16
CN1233247A (zh) 1999-10-27
IL129056A0 (en) 2000-02-17
ATE288908T1 (de) 2005-02-15
KR20000048966A (ko) 2000-07-25
AU4624097A (en) 1998-05-05
EP0934310B1 (en) 2005-02-09
DE69732490D1 (en) 2005-03-17
HUP9904180A3 (en) 2000-11-28
JP2001501632A (ja) 2001-02-06
NO991594L (no) 1999-06-08
HK1020958A1 (en) 2004-03-19
CN1111159C (zh) 2003-06-11
US6150382A (en) 2000-11-21
NZ334758A (en) 2000-11-24
US6221886B1 (en) 2001-04-24
US6166014A (en) 2000-12-26
DK0934310T3 (da) 2005-05-30
CZ122799A3 (cs) 1999-09-15
US6004985A (en) 1999-12-21

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