DK0858510T3 - Fremgangsmåde til fremstilling af O-acetylserin, L-cystein og L-cystein-beslægtede produkter - Google Patents

Fremgangsmåde til fremstilling af O-acetylserin, L-cystein og L-cystein-beslægtede produkter

Info

Publication number
DK0858510T3
DK0858510T3 DK96937217T DK96937217T DK0858510T3 DK 0858510 T3 DK0858510 T3 DK 0858510T3 DK 96937217 T DK96937217 T DK 96937217T DK 96937217 T DK96937217 T DK 96937217T DK 0858510 T3 DK0858510 T3 DK 0858510T3
Authority
DK
Denmark
Prior art keywords
cysteine
mutation
amino acid
acetylserine
wild
Prior art date
Application number
DK96937217T
Other languages
English (en)
Inventor
Peter Heinrich
Walfred Leinfelder
Original Assignee
Consortium Elektrochem Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Consortium Elektrochem Ind filed Critical Consortium Elektrochem Ind
Application granted granted Critical
Publication of DK0858510T3 publication Critical patent/DK0858510T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1025Acyltransferases (2.3)
    • C12N9/1029Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/12Methionine; Cysteine; Cystine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DK96937217T 1995-10-26 1996-10-24 Fremgangsmåde til fremstilling af O-acetylserin, L-cystein og L-cystein-beslægtede produkter DK0858510T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19539952A DE19539952A1 (de) 1995-10-26 1995-10-26 Verfahren zur Herstellung von O-Acetylserin, L-Cystein und L-Cystein-verwandten Produkten
PCT/EP1996/004613 WO1997015673A1 (de) 1995-10-26 1996-10-24 Verfahren zur herstellung von o-acetylserin, l-cystein und l-cystein-verwandten produkten

Publications (1)

Publication Number Publication Date
DK0858510T3 true DK0858510T3 (da) 2002-03-25

Family

ID=7775886

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96937217T DK0858510T3 (da) 1995-10-26 1996-10-24 Fremgangsmåde til fremstilling af O-acetylserin, L-cystein og L-cystein-beslægtede produkter

Country Status (17)

Country Link
US (1) US6218168B1 (da)
EP (1) EP0858510B1 (da)
JP (1) JP3329825B2 (da)
KR (1) KR100275287B1 (da)
CN (1) CN1155711C (da)
AT (1) ATE211175T1 (da)
BR (1) BR9610910A (da)
CA (1) CA2235752C (da)
CZ (1) CZ294539B6 (da)
DE (2) DE19539952A1 (da)
DK (1) DK0858510T3 (da)
ES (1) ES2169269T3 (da)
HU (1) HU224097B1 (da)
MX (1) MX9803317A (da)
PL (1) PL186403B1 (da)
TW (1) TW554043B (da)
WO (1) WO1997015673A1 (da)

Families Citing this family (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19726083A1 (de) * 1997-06-19 1998-12-24 Consortium Elektrochem Ind Mikroorganismen und Verfahren zur fermentativen Herstellung von L-Cystein, L-Cystin, N-Acetyl-Serin oder Thiazolidinderivaten
FR2787466B1 (fr) * 1998-12-17 2001-02-16 Rhone Poulenc Agrochimie Procede pour augmenter la teneur en cysteine, methionine et glutathion chez les plantes et plantes obtenues
DE19949579C1 (de) * 1999-10-14 2000-11-16 Consortium Elektrochem Ind Verfahren zur fermentativen Herstellung von L-Cystein oder L-Cystein-Derivaten
DE10136986A1 (de) * 2000-09-03 2002-03-21 Degussa Für Gene cysD, cysN, cysK, cysE und cysH kodierende Nukleotidsequenzen
US6822085B2 (en) 2000-09-03 2004-11-23 Degussa Ag Nucleotide sequences which code for the cysD, cysN, cysK, cysE and cysH genes
DE10046934A1 (de) * 2000-09-21 2002-04-18 Consortium Elektrochem Ind Verfahren zur fermentativen Herstellung von nicht-proteinogenen L-Aminosäuren
DE10104722A1 (de) * 2001-02-02 2002-08-14 Ipk Inst Fuer Pflanzengenetik Verfahren zur fermentativen Herstellung von Cystein, Cystin und Glutathion
DE10104721B4 (de) * 2001-02-02 2006-02-09 IPK-Institut für Pflanzengenetik und Kulturpflanzenforschung Verfahren zur Erhöhung des Gehalts von Schwefelverbindungen in Pflanzen
JP4622111B2 (ja) 2001-02-09 2011-02-02 味の素株式会社 L−システイン生産菌及びl−システインの製造法
DE10107002A1 (de) * 2001-02-15 2002-08-29 Consortium Elektrochem Ind Verfahren zur fermentativen Herstellung von O-Acetyl-L-Serin
EP1404855B1 (en) * 2001-07-11 2006-07-26 Degussa AG Process for the preparation of l-threonine using strains of the enterobacteriaceae family
EP1645623B1 (en) * 2001-09-28 2009-01-07 Ajinomoto Co., Inc. L-cysteine producing bacterium and method for producing L-cysteine
US7348037B2 (en) * 2002-08-16 2008-03-25 Evonik Degussa Gmbh Sulfur-containing animal-feed additives
EP2348107A3 (fr) 2003-02-18 2012-07-11 Metabolic Explorer Procédé de préparation de microorganismes évolués permettant la création ou la modification de voies métaboliques
DE10331291A1 (de) 2003-07-10 2005-02-17 Consortium für elektrochemische Industrie GmbH Varianten der 3-Phosphoglyceratdehydrogenase mit reduzierter Hemmung durch L-Serin und dafür codierende Gene
US7312058B2 (en) * 2003-07-16 2007-12-25 Ajinomoto Co., Ltd. Mutant serine acetyltransferase
RU2275425C2 (ru) * 2003-11-03 2006-04-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) Бактерия, принадлежащая к роду escherichia, - продуцент l-цистеина и способ получения l-цистеина
JP4479283B2 (ja) 2004-03-04 2010-06-09 味の素株式会社 L−システイン生産菌及びl−システインの製造法
JP2009118740A (ja) 2006-03-03 2009-06-04 Ajinomoto Co Inc L−アミノ酸の製造法
EP2351830B1 (en) 2006-03-23 2014-04-23 Ajinomoto Co., Inc. A method for producing an L-amino acid using bacterium of the Enterobacteriaceae family with attenuated expression of a gene coding for small RNA
EP2007873B1 (en) 2006-04-18 2015-11-18 Ajinomoto Co., Inc. A METHOD FOR PRODUCING AN L-AMINO ACID USING A BACTERIUM OF THE ENTEROBACTERIACEAE FAMILY WITH ATTENUATED EXPRESSION OF THE sfmACDFH-fimZ CLUSTER OR THE fimZ GENE
JP2009165355A (ja) 2006-04-28 2009-07-30 Ajinomoto Co Inc L−アミノ酸を生産する微生物及びl−アミノ酸の製造法
WO2007136133A1 (en) 2006-05-23 2007-11-29 Ajinomoto Co., Inc. A method for producing an l-amino acid using a bacterium of the enterobacteriaceae family
US8759042B2 (en) 2006-07-25 2014-06-24 Kyowa Hakko Bio Co., Ltd. Method for production of amino acid
RU2006143864A (ru) 2006-12-12 2008-06-20 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ СЕМЕЙСТВА ENTEROBACTERIACEAE, В КОТОРОЙ ОСЛАБЛЕНА ЭКСПРЕССИЯ ГЕНОВ cynT, cynS, cynX, ИЛИ cynR, ИЛИ ИХ КОМБИНАЦИИ
JP2010041920A (ja) 2006-12-19 2010-02-25 Ajinomoto Co Inc L−アミノ酸の製造法
CN101627110B (zh) 2007-01-22 2014-08-13 味之素株式会社 生产l-氨基酸的微生物和l-氨基酸的生产方法
DE102007007333A1 (de) 2007-02-14 2008-08-21 Wacker Chemie Ag Verfahren zur Reinigung von L-Cystein
JP2010110216A (ja) 2007-02-20 2010-05-20 Ajinomoto Co Inc L−アミノ酸または核酸の製造方法
JP2010110217A (ja) 2007-02-22 2010-05-20 Ajinomoto Co Inc L−アミノ酸生産菌及びl−アミノ酸の製造法
CN101715484B (zh) 2007-04-06 2014-02-19 协和发酵生化株式会社 二肽的制造方法
JP2011067095A (ja) 2008-01-10 2011-04-07 Ajinomoto Co Inc 発酵法による目的物質の製造法
EP2248906A4 (en) 2008-01-23 2012-07-11 Ajinomoto Kk PROCESS FOR THE PREPARATION OF L-AMINO ACID
RU2008105793A (ru) 2008-02-19 2009-08-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) Способ конструирования оперонов, содержащих трансляционно сопряженные гены, бактерия, содержащая такой оперон, способ продукции полезного метаболита и способ мониторинга экспрессии гена
JP5476545B2 (ja) * 2008-02-21 2014-04-23 味の素株式会社 L−システイン生産菌及びl−システインの製造法
ATE498017T1 (de) * 2008-03-06 2011-02-15 Ajinomoto Kk L-zystein-produzierendes bakterium und verfahren zur herstellung von l-zystein
JP5332237B2 (ja) * 2008-03-06 2013-11-06 味の素株式会社 L−システイン生産菌及びl−システインの製造法
EP2298880A4 (en) 2008-03-18 2012-02-08 Kyowa Hakko Kirin Co Ltd INDUSTRIALLY USEFUL MICROORGANISM
US8530203B2 (en) 2008-09-01 2013-09-10 Shinshu University Process for producing useful substance
PE20110369A1 (es) 2008-09-08 2011-06-24 Ajinomoto Kk Un microorganismo que produce l-aminoacido y un metodo para producir un l-aminoacido
WO2010084995A2 (en) 2009-01-23 2010-07-29 Ajinomoto Co.,Inc. A method for producing an l-amino acid
US9023622B2 (en) 2009-02-10 2015-05-05 Kyowa Hakko Bio Co., Ltd. Method for producing L-amino acid using a microorganism with decreased aspartate aminotransferase activity
JP5521347B2 (ja) * 2009-02-16 2014-06-11 味の素株式会社 L−アミノ酸生産菌及びl−アミノ酸の製造法
EP2400024A4 (en) 2009-02-18 2012-10-31 Univ Shinshu METHOD FOR PRODUCING A USEFUL SUBSTANCE
JP5463528B2 (ja) * 2009-02-25 2014-04-09 味の素株式会社 L−システイン生産菌及びl−システインの製造法
JP5359409B2 (ja) 2009-03-12 2013-12-04 味の素株式会社 L−システイン生産菌及びl−システインの製造法
EP2460883A4 (en) 2009-07-29 2013-01-16 Ajinomoto Kk PROCESS FOR THE PREPARATION OF L-AMINO ACID
RU2009136544A (ru) 2009-10-05 2011-04-10 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) (RU) Способ получения l-цистеина с использованием бактерии семейства enterobacteriaceae
WO2011065469A1 (ja) 2009-11-30 2011-06-03 味の素株式会社 L-システイン生産菌及びl-システインの製造法
RU2460793C2 (ru) * 2010-01-15 2012-09-10 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) Способ получения l-аминокислот с использованием бактерий семейства enterobacteriaceae
JP2013074795A (ja) 2010-02-08 2013-04-25 Ajinomoto Co Inc 変異型rpsA遺伝子及びL−アミノ酸の製造法
RU2471868C2 (ru) 2010-02-18 2013-01-10 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) Мутантная аденилатциклаза, днк, кодирующая ее, бактерия семейства enterobacteriaceae, содержащая указанную днк, и способ получения l-аминокислот
RU2501858C2 (ru) 2010-07-21 2013-12-20 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТЫ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ СЕМЕЙСТВА Enterobacteriaceae
RU2482188C2 (ru) 2010-07-21 2013-05-20 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) СПОСОБ ПОЛУЧЕНИЯ L-АРГИНИНА С ИСПОЛЬЗОВАНИЕМ БАКТЕРИЙ РОДА Escherichia, В КОТОРОЙ ИНАКТИВИРОВАН ОПЕРОН astCADBE
JP5803927B2 (ja) 2010-09-14 2015-11-04 味の素株式会社 含硫アミノ酸生産菌及び含硫アミノ酸の製造法
WO2012053794A2 (en) * 2010-10-20 2012-04-26 Cj Cheiljedang Corporation Microorganism producing o-phosphoserine and method of producing l-cysteine or derivatives thereof from o-phosphoserine using the same
JP2014036576A (ja) 2010-12-10 2014-02-27 Ajinomoto Co Inc L−アミノ酸の製造法
JP6301581B2 (ja) 2011-02-09 2018-03-28 協和発酵バイオ株式会社 発酵法による目的物質の製造法
JP2014087259A (ja) 2011-02-22 2014-05-15 Ajinomoto Co Inc L−システイン生産菌及びl−システインの製造法
US9234223B2 (en) 2011-04-01 2016-01-12 Ajinomoto Co., Inc. Method for producing L-cysteine
CN110016484A (zh) 2011-04-01 2019-07-16 味之素株式会社 用于产生l-半胱氨酸的方法
JP2014131487A (ja) 2011-04-18 2014-07-17 Ajinomoto Co Inc L−システインの製造法
DE102011075656A1 (de) 2011-05-11 2012-03-29 Wacker Chemie Ag Verfahren zur fermentativen Produktion von L-Cystin
DE102011078481A1 (de) 2011-06-30 2013-01-03 Wacker Chemie Ag Verfahren zur fermentativen Produktion von natürlichem L-Cystein
RU2011134436A (ru) 2011-08-18 2013-10-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") Способ получения l-аминокислоты с использованием бактерии семейства enterobacteriaceae, обладающей повышенной экспрессией генов каскада образования флагелл и клеточной подвижности
BR112014025215A2 (pt) 2012-04-13 2017-07-11 Kyowa Hakko Bio Co Ltd processo para produzir aminoácido
DE102012208359A1 (de) 2012-05-18 2013-11-21 Wacker Chemie Ag Verfahren zur fermentativen Produktion von L-Cystein und Derivaten dieser Aminosäure
DE102012016716A1 (de) 2012-08-22 2014-02-27 Forschungszentrum Jülich GmbH Verfahren zur Herstellung von Vektoren enthaltend ein für in seiner feedback-Inhibierung gemindertes oder ausgeschaltetes Enzym kodierendes Gen und deren Verwendung für die Herstellung von Aminosäuren und Nukleotiden
DE102012216527A1 (de) 2012-09-17 2014-03-20 Wacker Chemie Ag Verfahren zur fermentativen Produktion von L-Cystein und Derivaten dieser Aminosäure
US9611461B2 (en) 2013-03-19 2017-04-04 National University Corporation NARA Institute of Science and Technology Enterobacteriaceae bacteria exhibiting increased L-cysteine producing ability
RU2013118637A (ru) 2013-04-23 2014-10-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ СЕМЕЙСТВА ENTEROBACTERIACEAE, В КОТОРОЙ РАЗРЕГУЛИРОВАН ГЕН yjjK
DE102013209274A1 (de) 2013-05-17 2014-11-20 Wacker Chemie Ag Mikroorganismus und Verfahren zur fermentativen Überproduktion von Gamma-Glutamylcystein und Derivaten dieses Dipeptids
JP2016165225A (ja) 2013-07-09 2016-09-15 味の素株式会社 有用物質の製造方法
RU2013140115A (ru) 2013-08-30 2015-03-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ СЕМЕЙСТВА Enterobacteriaceae, В КОТОРОЙ НАРУШЕНА ЭКСПРЕССИЯ КЛАСТЕРА ГЕНОВ znuACB
RU2013144250A (ru) 2013-10-02 2015-04-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ СЕМЕЙСТВА Enterobacteriaceae, В КОТОРОЙ ОСЛАБЛЕНА ЭКСПРЕССИЯ ГЕНА, КОДИРУЮЩЕГО ФОСФАТНЫЙ ТРАНСПОРТЕР
BR112016007286B1 (pt) 2013-10-02 2021-07-20 Ajinomoto Co., Inc Métodos de controle de amônia e para produção de uma substância alvo, e, aparelho para controle de amônia
WO2015060314A1 (ja) 2013-10-21 2015-04-30 味の素株式会社 L-アミノ酸の製造法
RU2014105547A (ru) 2014-02-14 2015-08-20 Адзиномото Ко., Инк. СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ СЕМЕЙСТВА ENTEROBACTERIACEAE, ИМЕЮЩЕЙ СВЕРХЭКСПРЕССИРУЕМЫЙ ГЕН yajL
JP6759103B2 (ja) 2014-03-31 2020-09-23 インポッシブル フーズ インコーポレイテッド ひき肉レプリカ
RU2015120052A (ru) 2015-05-28 2016-12-20 Аджиномото Ко., Инк. Способ получения L-аминокислоты с использованием бактерии семейства Enterobacteriaceae, в которой ослаблена экспрессия гена gshA
WO2017146195A1 (en) 2016-02-25 2017-08-31 Ajinomoto Co., Inc. A method for producing l-amino acids using a bacterium of the family enterobacteriaceae overexpressing a gene encoding an iron exporter
JP7066977B2 (ja) 2017-04-03 2022-05-16 味の素株式会社 L-アミノ酸の製造法
WO2020071538A1 (en) 2018-10-05 2020-04-09 Ajinomoto Co., Inc. Method for producing target substance by bacterial fermentation
CN109517748A (zh) * 2018-11-30 2019-03-26 吉林大学 黑色食物小分子肽在修复肝损伤中的医用用途
WO2020171227A1 (en) 2019-02-22 2020-08-27 Ajinomoto Co., Inc. METHOD FOR PRODUCING L-AMINO ACIDS USING A BACTERIUM BELONGING TO THE FAMILY Enterobacteriaceae HAVING OVEREXPRESSED ydiJ GENE
WO2020204179A1 (en) 2019-04-05 2020-10-08 Ajinomoto Co., Inc. Method of producing l-amino acids
JP2022550084A (ja) 2019-09-25 2022-11-30 味の素株式会社 細菌の発酵によるl-アミノ酸の製造方法
KR20220149587A (ko) 2020-04-03 2022-11-08 와커 헤미 아게 시스틴의 생체촉매적 환원을 위한 효소-촉매화된 산화환원 시스템의 코어 구성요소로서의 생체촉매
CN116018400A (zh) 2020-06-26 2023-04-25 瓦克化学股份公司 改进的产生半胱氨酸的菌株
WO2023280382A1 (de) 2021-07-05 2023-01-12 Wacker Chemie Ag Verfahren zur enzymatischen oxidation von sulfinsäuren zu sulfonsäuren
CN114214341B (zh) * 2021-12-30 2023-12-26 山西大学 番茄SlSERAT1;1基因或其片段在植物发育过程中的应用
WO2023165684A1 (de) 2022-03-01 2023-09-07 Wacker Chemie Ag Verbesserte cystein produzierende stämme

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4965197A (en) 1987-06-12 1990-10-23 Massachusetts Institute Of Technology Coryneform expression and secretion system

Also Published As

Publication number Publication date
CN1200764A (zh) 1998-12-02
CZ126998A3 (cs) 1998-07-15
WO1997015673A1 (de) 1997-05-01
DE19539952A1 (de) 1997-04-30
DE59608521D1 (de) 2002-01-31
JP3329825B2 (ja) 2002-09-30
KR19990067120A (ko) 1999-08-16
ES2169269T3 (es) 2002-07-01
EP0858510B1 (de) 2001-12-19
US6218168B1 (en) 2001-04-17
HUP9900078A2 (hu) 1999-04-28
HUP9900078A3 (en) 2001-08-28
KR100275287B1 (ko) 2001-02-01
HU224097B1 (hu) 2005-05-30
CN1155711C (zh) 2004-06-30
CZ294539B6 (cs) 2005-01-12
BR9610910A (pt) 1999-07-13
TW554043B (en) 2003-09-21
EP0858510A1 (de) 1998-08-19
ATE211175T1 (de) 2002-01-15
CA2235752A1 (en) 1997-05-01
PL327187A1 (en) 1998-11-23
CA2235752C (en) 2002-04-16
PL186403B1 (pl) 2004-01-30
MX9803317A (es) 1998-09-30
JP2000504926A (ja) 2000-04-25

Similar Documents

Publication Publication Date Title
DK0858510T3 (da) Fremgangsmåde til fremstilling af O-acetylserin, L-cystein og L-cystein-beslægtede produkter
Hoben et al. Escherichia coli glutaminyl-tRNA synthetase. II. Characterization of the glnS gene product.
Eisen et al. Collagenolytic protease from the hepatopancreas of the fiddler crab, Uca pugilator. Purification and properties
Slotboom et al. Specific transformations at the N-terminal region of phospholipase A2
Prager et al. Amino acid sequence studies on bobwhite quail egg white lysozyme
DE69226636D1 (de) Stabilisierte enzyme
ATE293696T1 (de) Mutierte alpha-amylase enzyme mit erhöhter stabilität
HUT54213A (en) Process for the enzymatic removal of n-terminal sequence of proteins
BG101408A (en) Analogs of keratinocyte growth factor
Fukasawa et al. Comparison of dipeptidyl peptidase IV prepared from pig liver and kidney
US4466919A (en) Peptide substrates for mammalian collagenase
Heinrickson et al. [64] Acidic systeine protease inhibitors from pineapple stem
NO971621D0 (no) Keratinocyttvekstfaktoranaloger
ZA967411B (en) Blue copper oxidase mutants with enhanced activity
Pedersen et al. Amino‐Acid Sequence of the Peptide Segment Liberated during Activation of Prochymosin (Prorennin)
Morihara et al. Effect of secondary interaction on the enzymatic activity of subtilisin BPN′: Comparison with α-chymotrypsin, trypsin, and elastase
AU669483B2 (en) Nucleotide sequences and resistance proteins cycloheximide
Hofmann [49] Penicillocarboxypeptidases S-1 and S-2
EP1064296A4 (en) THERMOSTABLE DNA POLYMERASE FROM THERMOANAEROBACTER THERMOHYDROSULFURICUS
Moonen et al. The Primary Structure of the Phosphatidylcholine‐Exchange Protein from Bovine Liver: Isolation and Characterization of the Staphylococcal Protease Peptides and the Amino‐Acid Sequence of the N‐Terminal Half (Residues 1–122)
KR840004169A (ko) 프로인슐린 전구물질 유사체로부터 인슐린을 제조하는 방법
Chang et al. Histidine decarboxylase of Lactobacillus 30a. III. Composition and subunit structure
KR20040018459A (ko) 폴리펩티드 면역원성의 감소방법
DK0667872T3 (da) Mutantinterleukin 6 med forbedret biologisk aktivitet i forhold til vildtype-interleukin 6
Narita et al. Multiplicities and some enzymatic characteristics of ape pepsinogens and pepsins