BR112018017227A2 - método para produzir um l-aminoácido - Google Patents

método para produzir um l-aminoácido

Info

Publication number
BR112018017227A2
BR112018017227A2 BR112018017227A BR112018017227A BR112018017227A2 BR 112018017227 A2 BR112018017227 A2 BR 112018017227A2 BR 112018017227 A BR112018017227 A BR 112018017227A BR 112018017227 A BR112018017227 A BR 112018017227A BR 112018017227 A2 BR112018017227 A2 BR 112018017227A2
Authority
BR
Brazil
Prior art keywords
gene
produce
amino acid
fetb
feta
Prior art date
Application number
BR112018017227A
Other languages
English (en)
Inventor
Nikolaevich Chernyshov Alexey
Yurievna Romkina Anastasia
Borisovna Voroshilova Elvira
Yurievich Kiryukhin Mikhail
Georgievna Rostova Yulia
Original Assignee
Ajinomoto Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Publication of BR112018017227A2 publication Critical patent/BR112018017227A2/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/10—Citrulline; Arginine; Ornithine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/12—Methionine; Cysteine; Cystine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/14—Glutamic acid; Glutamine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/24—Proline; Hydroxyproline; Histidine

Abstract

a presente invenção provê um método para a produção de l-aminoácidos por fermentação usando uma bactéria que pertence à família enterobacteriaceae que foi modificada para superexpressar um gene que codifica um exportador de ferro, tal como um gene fetb, gene feta, gene fief ou uma combinação desses genes.
BR112018017227A 2016-02-25 2017-02-24 método para produzir um l-aminoácido BR112018017227A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU2016106614 2016-02-25
PCT/JP2017/007035 WO2017146195A1 (en) 2016-02-25 2017-02-24 A method for producing l-amino acids using a bacterium of the family enterobacteriaceae overexpressing a gene encoding an iron exporter

Publications (1)

Publication Number Publication Date
BR112018017227A2 true BR112018017227A2 (pt) 2019-02-05

Family

ID=58358793

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112018017227A BR112018017227A2 (pt) 2016-02-25 2017-02-24 método para produzir um l-aminoácido

Country Status (5)

Country Link
US (1) US10392638B2 (pt)
EP (1) EP3420096A1 (pt)
CN (1) CN109121422B (pt)
BR (1) BR112018017227A2 (pt)
WO (1) WO2017146195A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3788161A1 (en) 2018-05-04 2021-03-10 Ajinomoto Co., Inc. Method for producing l-methionine using a bacterium of the genus pantoea
CN113122560A (zh) * 2020-01-16 2021-07-16 南京理工大学 膜蛋白FieF的表达载体及其表达纯化方法
CN111718882B (zh) * 2020-06-04 2022-06-10 江南大学 一种用离子转运蛋白促进谷氨酸棒杆菌合成氨基酸的方法
CN116515726A (zh) * 2023-05-04 2023-08-01 浙江大学 定向富集厌氧氨氧化菌Ca.Brocadia的铁载体、突变株及其方法

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