BR102016008872A8 - método para produzir l-isoleucina - Google Patents

método para produzir l-isoleucina Download PDF

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Publication number
BR102016008872A8
BR102016008872A8 BR102016008872A BR102016008872A BR102016008872A8 BR 102016008872 A8 BR102016008872 A8 BR 102016008872A8 BR 102016008872 A BR102016008872 A BR 102016008872A BR 102016008872 A BR102016008872 A BR 102016008872A BR 102016008872 A8 BR102016008872 A8 BR 102016008872A8
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BR
Brazil
Prior art keywords
isoleucine
fermentation
producing
production
produce
Prior art date
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BR102016008872A
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English (en)
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BR102016008872A2 (pt
BR102016008872B1 (pt
Inventor
Dmitrievna Hook Christina
Sergeevna Eremina Natalia
Viktorovna Stoynova Natalia
Sergeevna Sidorova Tatiyana
Vasilievich Samsonov Valery
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Ajinomoto Kk
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Publication date
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Publication of BR102016008872A2 publication Critical patent/BR102016008872A2/pt
Publication of BR102016008872A8 publication Critical patent/BR102016008872A8/pt
Publication of BR102016008872B1 publication Critical patent/BR102016008872B1/pt

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

“método para produzir l-isoleucina” a presente invenção fornece um método para produzir lisoleucina por fermentação usando uma bactéria pertencendo à família enterobacteriaceae que está modificada para superexpressar o gene cyca. o método também permite reduzir a produção de aminoácido(s) subproduto(s) de l-isoleucina durante a fermentação da bactéria enterobacteriaceae tendo uma capacidade para produção de l-isoleucina.
BR102016008872-0A 2015-04-22 2016-04-20 Método para produzir l-isoleucina BR102016008872B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
RU2015114955A RU2015114955A (ru) 2015-04-22 2015-04-22 Способ получения L-изолейцина с использованием бактерии семейства Enterobacteriaceae, в которой сверхэкспрессирован ген cycA
RU2015114955 2015-04-22
JP2015114955 2015-04-22

Publications (3)

Publication Number Publication Date
BR102016008872A2 BR102016008872A2 (pt) 2019-06-04
BR102016008872A8 true BR102016008872A8 (pt) 2020-04-22
BR102016008872B1 BR102016008872B1 (pt) 2023-12-12

Family

ID=56081221

Family Applications (1)

Application Number Title Priority Date Filing Date
BR102016008872-0A BR102016008872B1 (pt) 2015-04-22 2016-04-20 Método para produzir l-isoleucina

Country Status (5)

Country Link
US (1) US9896704B2 (pt)
EP (1) EP3085705B1 (pt)
JP (1) JP6766426B2 (pt)
BR (1) BR102016008872B1 (pt)
RU (1) RU2015114955A (pt)

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WO2019225658A1 (en) 2018-05-23 2019-11-28 Ajinomoto Co., Inc. A method of producing the tripeptide gamma-glu-val-gly using enterobacteriaceae
KR102204917B1 (ko) * 2019-04-22 2021-01-20 씨제이제일제당 주식회사 L-히스티딘 생산능이 강화된 미생물 및 이를 이용한 히스티딘 생산방법
KR102175112B1 (ko) * 2019-04-22 2020-11-06 씨제이제일제당 주식회사 L-쓰레오닌 생산능이 강화된 미생물 및 이를 이용한 쓰레오닌 생산방법
WO2022005022A1 (ko) * 2020-06-29 2022-01-06 씨제이제일제당 (주) L-이소류신 생산능이 강화된 미생물 및 이를 이용한 l-이소류신 생산방법
CN113046398A (zh) * 2021-05-18 2021-06-29 通辽梅花生物科技有限公司 一种稳定高效生产l-异亮氨酸的发酵方法及发酵稳定剂
KR20230094761A (ko) * 2021-12-21 2023-06-28 씨제이제일제당 (주) L-이소루신 생산 미생물 및 이를 이용한 l-이소루신 생산 방법
WO2024094483A1 (en) * 2022-11-03 2024-05-10 Evonik Operations Gmbh Improved biotechnological process to produce guanidinoacetic acid (gaa) by targeted introduction or by increasing the activity of a transmembrane transport protein belonging to the amino acid-polyamine-organocation superfamily

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Also Published As

Publication number Publication date
US9896704B2 (en) 2018-02-20
JP6766426B2 (ja) 2020-10-14
BR102016008872A2 (pt) 2019-06-04
RU2015114955A (ru) 2016-11-10
EP3085705A1 (en) 2016-10-26
US20160312254A1 (en) 2016-10-27
EP3085705B1 (en) 2018-06-13
JP2016202182A (ja) 2016-12-08
BR102016008872B1 (pt) 2023-12-12

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