US5817672A
(en)
*
|
1991-12-06 |
1998-10-06 |
Hoechst Marion Roussel, Inc. |
Trans cyclopentanyl purine analogs useful as immunosuppressants
|
US5817661A
(en)
|
1991-12-06 |
1998-10-06 |
Hoechst Marion Roussel, Inc. |
Trans cyclopentanyl purine analogs useful as immunosuppressants
|
US5817660A
(en)
*
|
1991-12-06 |
1998-10-06 |
Hoechst Marion Roussel, Inc. |
Trans cyclopentanyl purine analogs useful as immunosuppressants
|
US5723466A
(en)
*
|
1991-12-06 |
1998-03-03 |
Hoechst Marion Roussel, Inc. |
Trans cyclopentanyl purine analogs useful as immunosuppressants
|
US5648516A
(en)
*
|
1994-07-20 |
1997-07-15 |
Minnesota Mining And Manufacturing Company |
Fused cycloalkylimidazopyridines
|
DE69724941T2
(de)
*
|
1996-03-21 |
2004-07-15 |
Banyu Pharmaceutical Co., Ltd. |
Aminopyridin-derivate
|
US5741908A
(en)
|
1996-06-21 |
1998-04-21 |
Minnesota Mining And Manufacturing Company |
Process for reparing imidazoquinolinamines
|
US6039969A
(en)
|
1996-10-25 |
2000-03-21 |
3M Innovative Properties Company |
Immune response modifier compounds for treatment of TH2 mediated and related diseases
|
UA67760C2
(uk)
*
|
1997-12-11 |
2004-07-15 |
Міннесота Майнінг Енд Мануфакчурінг Компані |
Імідазонафтиридин та тетрагідроімідазонафтиридин, фармацевтична композиція, спосіб індукування біосинтезу цитокінів та спосіб лікування вірусної інфекції, проміжні сполуки
|
US6110929A
(en)
*
|
1998-07-28 |
2000-08-29 |
3M Innovative Properties Company |
Oxazolo, thiazolo and selenazolo [4,5-c]-quinolin-4-amines and analogs thereof
|
US6518280B2
(en)
*
|
1998-12-11 |
2003-02-11 |
3M Innovative Properties Company |
Imidazonaphthyridines
|
CA2361936C
(en)
|
1999-01-08 |
2009-06-16 |
3M Innovative Properties Company |
Formulations comprising imiquimod or other immune response modifiers for treating mucosal conditions
|
US6486168B1
(en)
|
1999-01-08 |
2002-11-26 |
3M Innovative Properties Company |
Formulations and methods for treatment of mucosal associated conditions with an immune response modifier
|
US20020058674A1
(en)
|
1999-01-08 |
2002-05-16 |
Hedenstrom John C. |
Systems and methods for treating a mucosal surface
|
US6558951B1
(en)
*
|
1999-02-11 |
2003-05-06 |
3M Innovative Properties Company |
Maturation of dendritic cells with immune response modifying compounds
|
US6541485B1
(en)
|
1999-06-10 |
2003-04-01 |
3M Innovative Properties Company |
Urea substituted imidazoquinolines
|
US6331539B1
(en)
*
|
1999-06-10 |
2001-12-18 |
3M Innovative Properties Company |
Sulfonamide and sulfamide substituted imidazoquinolines
|
US6756382B2
(en)
|
1999-06-10 |
2004-06-29 |
3M Innovative Properties Company |
Amide substituted imidazoquinolines
|
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(en)
|
1999-06-10 |
2002-09-17 |
3M Innovative Properties Company |
Amide substituted imidazoquinolines
|
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(en)
|
1999-06-10 |
2003-06-03 |
3M Innovative Properties Company |
Urea substituted imidazoquinolines
|
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(en)
|
1999-11-05 |
2005-07-12 |
3M Innovative Properties Co. |
Dye labeled imidazoquinoline compounds
|
US6376669B1
(en)
|
1999-11-05 |
2002-04-23 |
3M Innovative Properties Company |
Dye labeled imidazoquinoline compounds
|
JP3436512B2
(ja)
*
|
1999-12-28 |
2003-08-11 |
株式会社デンソー |
アクセル装置
|
US6894060B2
(en)
|
2000-03-30 |
2005-05-17 |
3M Innovative Properties Company |
Method for the treatment of dermal lesions caused by envenomation
|
US20020107262A1
(en)
*
|
2000-12-08 |
2002-08-08 |
3M Innovative Properties Company |
Substituted imidazopyridines
|
US6667312B2
(en)
|
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2003-12-23 |
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Thioether substituted imidazoquinolines
|
US6664265B2
(en)
|
2000-12-08 |
2003-12-16 |
3M Innovative Properties Company |
Amido ether substituted imidazoquinolines
|
UA74852C2
(en)
*
|
2000-12-08 |
2006-02-15 |
3M Innovative Properties Co |
Urea-substituted imidazoquinoline ethers
|
US6677347B2
(en)
*
|
2000-12-08 |
2004-01-13 |
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Sulfonamido ether substituted imidazoquinolines
|
US6677348B2
(en)
*
|
2000-12-08 |
2004-01-13 |
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Aryl ether substituted imidazoquinolines
|
US20020110840A1
(en)
*
|
2000-12-08 |
2002-08-15 |
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Screening method for identifying compounds that selectively induce interferon alpha
|
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(en)
|
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2003-04-08 |
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Urea substituted imidazopyridines
|
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(en)
|
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2003-02-25 |
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Sulfonamido substituted imidazopyridines
|
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(en)
*
|
2000-12-08 |
2006-01-16 |
3M Innovative Properties Co |
Substituted imidazopyridines
|
US6664260B2
(en)
|
2000-12-08 |
2003-12-16 |
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Heterocyclic ether substituted imidazoquinolines
|
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(en)
|
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Thioether substituted imidazoquinolines
|
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(en)
|
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Urea substituted imidazoquinoline ethers
|
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(en)
|
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2003-12-09 |
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Amido ether substituted imidazoquinolines
|
WO2006091720A2
(en)
*
|
2000-12-08 |
2006-08-31 |
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Compositions and methods for targeted delivery of immune response modifiers
|
US6545016B1
(en)
|
2000-12-08 |
2003-04-08 |
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Amide substituted imidazopyridines
|
US7226928B2
(en)
*
|
2001-06-15 |
2007-06-05 |
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Methods for the treatment of periodontal disease
|
JP2005501550A
(ja)
*
|
2001-08-30 |
2005-01-20 |
スリーエム イノベイティブ プロパティズ カンパニー |
免疫反応調整剤分子を用いた形質細胞様樹状細胞を成熟させる方法
|
DE60230340D1
(de)
*
|
2001-11-16 |
2009-01-22 |
3M Innovative Properties Co |
N-Ä4-(4-Amino-2-ethyl-1H-imidazoÄ4,5-cÜchinolin-1-yl)butylÜmethanesulfonamide, diese enthaltende pharmazeutische Zusammensetzung und deren Verwendung
|
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(en)
*
|
2001-11-29 |
2005-12-23 |
3M Innovative Properties Co |
Pharmaceutical formulations comprising an immune response modifier
|
CA2365732A1
(en)
*
|
2001-12-20 |
2003-06-20 |
Ibm Canada Limited-Ibm Canada Limitee |
Testing measurements
|
US6677349B1
(en)
*
|
2001-12-21 |
2004-01-13 |
3M Innovative Properties Company |
Sulfonamide and sulfamide substituted imidazoquinolines
|
ES2541132T3
(es)
*
|
2002-02-22 |
2015-07-16 |
Meda Ab |
Método para reducir y tratar la inmunosupresión inducida por UV-B
|
JP2005533752A
(ja)
*
|
2002-03-19 |
2005-11-10 |
パウダーメド リミテッド |
Hivdnaワクチン接種におけるアジュバントとしてのイミダゾキノリンアミン
|
ATE491471T1
(de)
*
|
2002-03-19 |
2011-01-15 |
Powderject Res Ltd |
Adjuvantien für dns impstoffe basierend auf imidazochinoline
|
EP3006043B1
(en)
*
|
2002-04-04 |
2019-05-29 |
Zoetis Belgium S.A. |
Immunostimulatory g,u-containing oligoribonucleotides
|
WO2003101949A2
(en)
*
|
2002-05-29 |
2003-12-11 |
3M Innovative Properties Company |
Process for imidazo[4,5-c]pyridin-4-amines
|
MXPA04012199A
(es)
*
|
2002-06-07 |
2005-02-25 |
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Imidazopiridinas sustituidas con eter.
|
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(en)
|
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2002-08-14 |
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Viral inhibitors
|
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|
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2010-11-17 |
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Immunostimulatory compositions and methods of stimulating an immune response
|
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(en)
*
|
2002-09-26 |
2004-04-19 |
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1h-imidazo dimers
|
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(en)
|
2002-10-31 |
2006-04-19 |
Amgen Inc |
ANTI-INFLAMMATORY AGENTS
|
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(en)
*
|
2002-12-11 |
2004-06-30 |
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Gene expression systems and recombinant cell lines
|
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*
|
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2004-06-24 |
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Assays relating to toll-like receptor activity
|
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(en)
|
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2004-07-15 |
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Aryl / hetaryl substituted imidazoquinolines
|
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(en)
*
|
2002-12-30 |
2013-11-26 |
3M Innovative Properties Company |
Immunostimulatory combinations
|
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*
|
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2008-05-20 |
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Methods and compositions related to IRM compounds and Toll-like receptor 8
|
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(en)
*
|
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2009-07-22 |
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SELECTIVE MODULATION OF TLR-MEDIATED BIOLOGICAL ACTIVITY
|
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(en)
|
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2004-09-16 |
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Prophylactic treatment of uv-induced epidermal neoplasia
|
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(en)
*
|
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2008-01-16 |
3M Innovative Properties Co |
1-AMINO-1H-imidazoquinolines
|
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(en)
*
|
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2007-01-16 |
3M Innovative Properties Company |
1-Amino 1H-imidazoquinolines
|
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(en)
*
|
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2012-11-06 |
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Methods of improving skin quality
|
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*
|
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2004-09-23 |
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Method of tattoo removal
|
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*
|
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Methods for treating skin lesions
|
US20040192585A1
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*
|
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2004-09-30 |
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Treatment for basal cell carcinoma
|
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|
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2011-02-22 |
Novartis Vaccines And Diagnostics, Inc. |
Use of small molecule compounds for immunopotentiation
|
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(en)
|
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2004-12-30 |
Miller Richard L. |
Methods and compositions for enhancing immune response
|
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*
|
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Delivery of immune response modifier compounds using metal-containing particulate support materials
|
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*
|
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2004-10-28 |
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Compositions and methods for induction of opioid receptors
|
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(en)
*
|
2003-06-06 |
2004-12-23 |
3M Innovative Properties Company |
PROCESS FOR IMIDAZO[4,5-c]PYRIDIN-4-AMINES
|
AR044466A1
(es)
*
|
2003-06-06 |
2005-09-14 |
3M Innovative Properties Co |
Proceso para la preparacion de imidazo [4,5-c] piridin-4-aminas
|
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(en)
*
|
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2005-02-10 |
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Compositions for encapsulation and controlled release
|
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*
|
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2013-03-19 |
3M Innovative Properties Company |
Formulations containing an immune response modifier
|
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(en)
*
|
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2005-03-16 |
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Oxime substituted imidazo-containing compounds
|
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(en)
*
|
2003-08-14 |
2013-05-28 |
3M Innovative Properties Company |
Substituted 1h-imidazo[4,5-c]pyridin-4-amines,1h-imidazo[4,5-c]quinolin -4-amines and 1h-imidazo[4,5-c]naphthyridin-4-amines as immune response modifiers
|
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(ja)
*
|
2003-08-25 |
2007-03-01 |
スリーエム イノベイティブ プロパティズ カンパニー |
免疫刺激性の組み合わせおよび治療
|
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(en)
|
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2015-02-24 |
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Delivery of immune response modifier compounds
|
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(en)
|
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2012-10-30 |
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Aryloxy and arylalkyleneoxy substituted imidazoquinolines
|
JP2007504172A
(ja)
*
|
2003-09-02 |
2007-03-01 |
スリーエム イノベイティブ プロパティズ カンパニー |
粘膜に関連した症状の処置に関する方法
|
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(ja)
|
2003-09-05 |
2007-03-01 |
スリーエム イノベイティブ プロパティズ カンパニー |
Cd5+b細胞リンパ腫の治療方法
|
EP1664342A4
(en)
*
|
2003-09-17 |
2007-12-26 |
3M Innovative Properties Co |
SELECTIVE MODULATION OF TLR GENE EXPRESSION
|
WO2005033049A2
(en)
*
|
2003-10-01 |
2005-04-14 |
Taro Pharmaceuticals U.S.A., Inc. |
METHOD OF PREPARING 4-AMINO-1H-IMIDAZO(4,5-c)QUINOLINES AND ACID ADDITION SALTS THEREOF
|
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(en)
*
|
2003-10-03 |
2009-06-09 |
Coley Pharmaceutical Group, Inc. |
Pyrazolopyridines and analogs thereof
|
US20090075980A1
(en)
*
|
2003-10-03 |
2009-03-19 |
Coley Pharmaceutical Group, Inc. |
Pyrazolopyridines and Analogs Thereof
|
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(ja)
|
2003-10-03 |
2012-10-10 |
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アルコキシ置換イミダゾキノリン
|
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(en)
|
2003-10-03 |
2009-12-24 |
3M Innovative Properties Co |
Pyrazolopyridines and analags thereof
|
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(en)
*
|
2003-10-31 |
2005-05-12 |
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Neutrophil activation by immune response modifier compounds
|
CN1906193A
(zh)
*
|
2003-11-14 |
2007-01-31 |
3M创新有限公司 |
肟取代的咪唑环化合物
|
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(en)
|
2003-11-14 |
2005-06-02 |
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Hydroxylamine substituted imidazo ring compounds
|
AR046781A1
(es)
|
2003-11-25 |
2005-12-21 |
3M Innovative Properties Co |
Derivados de imidazoquinolinas. composiciones farmaceuticas.
|
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(en)
*
|
2003-11-25 |
2009-11-04 |
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HYDROXYLAMINE, AND IMIDAZOQUINOLEINS, AND IMIDAZOPYRIDINES AND IMIDAZONAPHTYRIDINE SUBSTITUTED WITH OXIME
|
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(en)
*
|
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2005-10-13 |
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Therapeutic combinations and methods including IRM compounds
|
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(en)
*
|
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2009-06-17 |
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THERAPEUTIC COMBINATIONS AND PROCESSES WITH IRM COMPOUNDS
|
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(en)
|
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2005-08-25 |
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Sulfone substituted imidazo ring ethers
|
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(en)
*
|
2003-12-29 |
2005-07-21 |
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Piperazine, [1,4]diazepane, [1,4]diazocane, and [1,5]diazocane fused imidazo ring compounds
|
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|
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2005-07-21 |
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Arylalkenyl and arylalkynyl substituted imidazoquinolines
|
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(en)
|
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2005-07-21 |
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Imidazoquinolinyl, imidazopyridinyl, and imidazonaphthyridinyl sulfonamides
|
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(en)
*
|
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2005-10-27 |
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Enhancement of immune responses
|
AU2005222995B2
(en)
*
|
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2010-08-26 |
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|
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(en)
|
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2005-10-13 |
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Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines
|
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(en)
*
|
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2008-08-27 |
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|
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(ja)
*
|
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2008-02-28 |
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粘膜ワクチン接種のための組成物および方法
|
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(en)
|
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2006-07-27 |
Novartis Vaccines And Diagnostics Inc. |
Alphavirus vectors for respiratory pathogen vaccines
|
US20050267145A1
(en)
*
|
2004-05-28 |
2005-12-01 |
Merrill Bryon A |
Treatment for lung cancer
|
US20080015184A1
(en)
*
|
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2008-01-17 |
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|
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(en)
|
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2011-09-13 |
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Nitrogen containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines
|
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(en)
*
|
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2006-01-26 |
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Substituted imidazo ring systems and methods
|
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(en)
|
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2011-03-01 |
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|
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(en)
|
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Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and method
|
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(en)
|
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2013-09-24 |
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|
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(en)
|
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Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines
|
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(en)
*
|
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2016-08-03 |
3M Innovative Properties Company |
Substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines
|
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(en)
|
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2007-04-04 |
Novartis Vaccines and Diagnostics, Inc. |
Small molecule immunopotentiators and assays for their detection
|
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(en)
|
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2006-01-05 |
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Compounds for immunopotentiation
|
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(zh)
|
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2007-08-29 |
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咪唑并[4,5-d]嘧啶类、其应用和制备方法
|
US20060045886A1
(en)
*
|
2004-08-27 |
2006-03-02 |
Kedl Ross M |
HIV immunostimulatory compositions
|
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(en)
*
|
2004-09-02 |
2011-06-02 |
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1-alkoxy 1H-imidazo ring systems and methods
|
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(en)
|
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2006-03-16 |
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2-amino 1H imidazo ring systems and methods
|
US20090270443A1
(en)
*
|
2004-09-02 |
2009-10-29 |
Doris Stoermer |
1-amino imidazo-containing compounds and methods
|
US20080193468A1
(en)
*
|
2004-09-08 |
2008-08-14 |
Children's Medical Center Corporation |
Method for Stimulating the Immune Response of Newborns
|
US20080213308A1
(en)
*
|
2004-09-14 |
2008-09-04 |
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Imidazoquinoline Compounds
|
JP2008515928A
(ja)
*
|
2004-10-08 |
2008-05-15 |
スリーエム イノベイティブ プロパティズ カンパニー |
Dnaワクチンのためのアジュバント
|
WO2006063072A2
(en)
*
|
2004-12-08 |
2006-06-15 |
3M Innovative Properties Company |
Immunomodulatory compositions, combinations and methods
|
US8080560B2
(en)
*
|
2004-12-17 |
2011-12-20 |
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Immune response modifier formulations containing oleic acid and methods
|
JP2008526765A
(ja)
|
2004-12-30 |
2008-07-24 |
スリーエム イノベイティブ プロパティズ カンパニー |
皮膚転移の処置
|
US8436176B2
(en)
*
|
2004-12-30 |
2013-05-07 |
Medicis Pharmaceutical Corporation |
Process for preparing 2-methyl-1-(2-methylpropyl)-1H-imidazo[4,5-c][1,5]naphthyridin-4-amine
|
US8034938B2
(en)
|
2004-12-30 |
2011-10-11 |
3M Innovative Properties Company |
Substituted chiral fused [1,2]imidazo[4,5-c] ring compounds
|
WO2006074003A2
(en)
*
|
2004-12-30 |
2006-07-13 |
3M Innovative Properties Company |
CHIRAL FUSED [1,2]IMIDAZO[4,5-c] RING COMPOUNDS
|
CA2592897A1
(en)
*
|
2004-12-30 |
2006-07-13 |
Takeda Pharmaceutical Company Limited |
1-(2-methylpropyl)-1h-imidazo[4,5-c][1,5]naphthyridin-4-amine ethanesulfonate and 1-(2-methylpropyl)-1h-imidazo[4,5-c][1,5]naphthyridin-4-amine methanesulfonate
|
WO2006084251A2
(en)
|
2005-02-04 |
2006-08-10 |
Coley Pharmaceutical Group, Inc. |
Aqueous gel formulations containing immune reponse modifiers
|
AU2006212765B2
(en)
|
2005-02-09 |
2012-02-02 |
3M Innovative Properties Company |
Alkyloxy substituted thiazoloquinolines and thiazolonaphthyridines
|
AU2006338521A1
(en)
|
2005-02-09 |
2007-10-11 |
Coley Pharmaceutical Group, Inc. |
Oxime and hydroxylamine substituted thiazolo(4,5-c) ring compounds and methods
|
CA2597446A1
(en)
|
2005-02-11 |
2006-08-31 |
Coley Pharmaceutical Group, Inc. |
Substituted imidazoquinolines and imidazonaphthyridines
|
JP2008530113A
(ja)
|
2005-02-11 |
2008-08-07 |
コーリー ファーマシューティカル グループ,インコーポレイテッド |
オキシムおよびヒドロキシラミン置換イミダゾ[4,5−c]環化合物および方法
|
EP1858920B1
(en)
|
2005-02-18 |
2016-02-03 |
GlaxoSmithKline Biologicals SA |
Proteins and nucleic acids from meningitis/sepsis-associated escherichia coli
|
SG164344A1
(en)
|
2005-02-18 |
2010-09-29 |
Novartis Vaccines & Diagnostics Srl |
Immunogens from uropathogenic escherichia coli
|
AU2006216686A1
(en)
|
2005-02-23 |
2006-08-31 |
Coley Pharmaceutical Group, Inc. |
Method of preferentially inducing the biosynthesis of interferon
|
AU2006216799A1
(en)
|
2005-02-23 |
2006-08-31 |
Coley Pharmaceutical Group, Inc. |
Hydroxyalkyl substituted imidazonaphthyridines
|
US8178677B2
(en)
|
2005-02-23 |
2012-05-15 |
3M Innovative Properties Company |
Hydroxyalkyl substituted imidazoquinolines
|
JP2008531567A
(ja)
|
2005-02-23 |
2008-08-14 |
コーリー ファーマシューティカル グループ,インコーポレイテッド |
ヒドロキシアルキル置換イミダゾキノリン化合物および方法
|
MX2007011112A
(es)
|
2005-03-14 |
2007-11-07 |
Graceway Pharmaceuticals Llc |
Metodo para tratar queratosis actinica.
|
US7943610B2
(en)
|
2005-04-01 |
2011-05-17 |
3M Innovative Properties Company |
Pyrazolopyridine-1,4-diamines and analogs thereof
|
US7943636B2
(en)
|
2005-04-01 |
2011-05-17 |
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1-substituted pyrazolo (3,4-C) ring compounds as modulators of cytokine biosynthesis for the treatment of viral infections and neoplastic diseases
|
JP2008539252A
(ja)
|
2005-04-25 |
2008-11-13 |
スリーエム イノベイティブ プロパティズ カンパニー |
免疫活性化組成物
|
EP2614709A1
(en)
|
2005-07-18 |
2013-07-17 |
Novartis AG |
Small animal model for HCV replication
|
RS20080128A
(en)
*
|
2005-09-02 |
2009-05-06 |
Pfizer Inc., |
Hydroxy substituted 1h-imidazopyridines and methods
|
EA200800782A1
(ru)
|
2005-09-09 |
2008-08-29 |
Коли Фармасьютикал Груп, Инк. |
ПРОИЗВОДНЫЕ АМИДА И КАРБАМАТА N-{2-[4-АМИНО-2-(ЭТОКСИМЕТИЛ)-1Н-ИМИДАЗОЛО[4,5-c]ХИНОЛИН-1-IL]-1,1-ДИМЕТИЛЭТИЛ}МЕТАНСУЛЬФОНАМИДА И СПОСОБЫ
|
ZA200803029B
(en)
*
|
2005-09-09 |
2009-02-25 |
Coley Pharm Group Inc |
Amide and carbamate derivatives of alkyl substituted /V-[4-(4-amino-1H-imidazo[4,5-c] quinolin-1-yl)butyl] methane-sulfonamides and methods
|
US8889154B2
(en)
|
2005-09-15 |
2014-11-18 |
Medicis Pharmaceutical Corporation |
Packaging for 1-(2-methylpropyl)-1H-imidazo[4,5-c] quinolin-4-amine-containing formulation
|
WO2007047749A1
(en)
|
2005-10-18 |
2007-04-26 |
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Mucosal and systemic immunizations with alphavirus replicon particles
|
JP2009514839A
(ja)
|
2005-11-04 |
2009-04-09 |
ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル |
サイトカイン誘導剤を含むアジュバントインフルエンザワクチン
|
PT1951299E
(pt)
|
2005-11-04 |
2012-02-28 |
Novartis Vaccines & Diagnostic |
Vacinas contra a gripe que incluem combinações de adjuvantes particulados e imuno-potenciadores
|
JP5247458B2
(ja)
|
2005-11-04 |
2013-07-24 |
スリーエム・イノベイティブ・プロパティーズ・カンパニー |
ヒドロキシ及びアルコキシ置換1h−イミダゾキノリン及び方法
|
EP1945252B1
(en)
|
2005-11-04 |
2013-05-29 |
Novartis Vaccines and Diagnostics S.r.l. |
Vaccines comprising purified surface antigens prepared from influenza viruses grown in cell culture, adjuvanted with squalene
|
CA2628206A1
(en)
|
2005-11-04 |
2007-05-10 |
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Influenza vaccine with reduced amount of oil-in-water emulsion as adjuvant
|
WO2007081447A2
(en)
|
2005-11-22 |
2007-07-19 |
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Norovirus and sapovirus antigens
|
JO2660B1
(en)
|
2006-01-20 |
2012-06-17 |
نوفارتيس ايه جي |
Pi-3 inhibitors and methods of use
|
JP6087041B2
(ja)
|
2006-01-27 |
2017-03-08 |
ノバルティス アーゲー |
血球凝集素およびマトリックスタンパク質を含むインフルエンザウイルスワクチン
|
PE20070978A1
(es)
*
|
2006-02-14 |
2007-11-15 |
Novartis Ag |
COMPUESTOS HETEROCICLICOS COMO INHIBIDORES DE FOSFATIDILINOSITOL 3-QUINASAS (PI3Ks)
|
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(en)
|
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2007-09-07 |
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Immune response modifier conjugates
|
WO2007106854A2
(en)
|
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2007-09-20 |
Coley Pharmaceutical Group, Inc. |
Hydroxy and alkoxy substituted 1h-imidazonaphthyridines and methods
|
CA2646891A1
(en)
*
|
2006-03-23 |
2007-09-27 |
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Immunopotentiating compounds
|
CA2646539A1
(en)
*
|
2006-03-23 |
2007-09-27 |
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Imidazoquinoxaline compounds as immunomodulators
|
WO2007109810A2
(en)
*
|
2006-03-23 |
2007-09-27 |
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Methods for the preparation of imidazole-containing compounds
|
WO2007110776A1
(en)
|
2006-03-24 |
2007-10-04 |
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Storage of influenza vaccines without refrigeration
|
EP2382988A1
(en)
|
2006-03-31 |
2011-11-02 |
Novartis AG |
Combined mucosal and parenteral immunization against HIV
|
TW200808739A
(en)
*
|
2006-04-06 |
2008-02-16 |
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Quinazolines for PDK1 inhibition
|
ATE522541T1
(de)
|
2006-06-09 |
2011-09-15 |
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|
US7906506B2
(en)
|
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2011-03-15 |
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Substituted chiral fused [1,2] imidazo [4,5-c] ring compounds and methods
|
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(en)
|
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2006-08-30 |
Novartis Ag |
Vaccines
|
US8124096B2
(en)
*
|
2006-07-31 |
2012-02-28 |
3M Innovative Properties Company |
Immune response modifier compositions and methods
|
EP2586790A3
(en)
|
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2013-08-14 |
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Immunogens from uropathogenic Escherichia coli
|
US8178539B2
(en)
|
2006-09-06 |
2012-05-15 |
3M Innovative Properties Company |
Substituted 3,4,6,7-tetrahydro-5H-1,2a,4a,8-tetraazacyclopenta[cd]phenalenes and methods
|
ES2536401T3
(es)
|
2006-09-11 |
2015-05-25 |
Novartis Ag |
Fabricación de vacunas contra virus de la gripe sin usar huevos
|
ES2480491T3
(es)
|
2006-12-06 |
2014-07-28 |
Novartis Ag |
Vacunas incluyendo antígeno de cuatro cepas de virus de la gripe
|
EP2121023A1
(en)
*
|
2006-12-22 |
2009-11-25 |
3M Innovative Properties Company |
Controlled release composition and process
|
US20080149123A1
(en)
|
2006-12-22 |
2008-06-26 |
Mckay William D |
Particulate material dispensing hairbrush with combination bristles
|
GB0700562D0
(en)
|
2007-01-11 |
2007-02-21 |
Novartis Vaccines & Diagnostic |
Modified Saccharides
|
MX2009009936A
(es)
*
|
2007-03-20 |
2010-02-11 |
Curis Inc |
Amino piridina fusionada como inhibidores de hsp90.
|
BRPI0813866A2
(pt)
|
2007-06-27 |
2015-01-06 |
Novartis Ag |
Vacinas contra influenza com baixo teor de aditivos
|
GB0714963D0
(en)
|
2007-08-01 |
2007-09-12 |
Novartis Ag |
Compositions comprising antigens
|
ES2561483T3
(es)
|
2007-09-12 |
2016-02-26 |
Glaxosmithkline Biologicals Sa |
Antígenos mutantes de GAS57 y anticuerpos de GAS57
|
GB0810305D0
(en)
|
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2008-07-09 |
Novartis Ag |
Influenza vaccination
|
CN101952282A
(zh)
|
2007-12-20 |
2011-01-19 |
诺瓦提斯公司 |
用作pi 3激酶抑制剂的噻唑衍生物
|
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(en)
|
2008-10-08 |
2008-11-12 |
Novartis Ag |
Fermentation processes for cultivating streptococci and purification processes for obtaining cps therefrom
|
KR101773114B1
(ko)
|
2007-12-21 |
2017-08-30 |
노파르티스 아게 |
스트렙토라이신 o의 돌연변이 형태
|
JP5518041B2
(ja)
|
2008-03-18 |
2014-06-11 |
ノバルティス アーゲー |
インフルエンザウイルスワクチン抗原の調製における改良
|
US8465751B2
(en)
|
2009-01-12 |
2013-06-18 |
Novartis Ag |
Cna—B domain antigens in vaccines against gram positive bacteria
|
EP3549602A1
(en)
|
2009-03-06 |
2019-10-09 |
GlaxoSmithKline Biologicals S.A. |
Chlamydia antigens
|
CA3033133C
(en)
|
2009-03-25 |
2021-11-09 |
The Board Of Regents Of The University Of Texas System |
Compositions for stimulation of mammalian innate immune resistance to pathogens
|
SI2510947T1
(sl)
|
2009-04-14 |
2016-05-31 |
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Sestavki za imunizacijo proti Staphylococcus aureus
|
KR20120027276A
(ko)
|
2009-04-27 |
2012-03-21 |
노파르티스 아게 |
인플루엔자를 예방하기 위한 면역증강된 백신
|
US8293753B2
(en)
|
2009-07-02 |
2012-10-23 |
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Substituted 2-carboxamide cycloamino ureas
|
BR112012001666A2
(pt)
|
2009-07-15 |
2019-09-24 |
Novartis Ag |
composições de proteína rsv f e métodos para fazer as mesmas
|
JP2012532626A
(ja)
|
2009-07-16 |
2012-12-20 |
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無毒化されたEscherichiacoli免疫原
|
US20110033515A1
(en)
*
|
2009-08-04 |
2011-02-10 |
Rst Implanted Cell Technology |
Tissue contacting material
|
GB0918392D0
(en)
|
2009-10-20 |
2009-12-02 |
Novartis Ag |
Diagnostic and therapeutic methods
|
GB0919690D0
(en)
|
2009-11-10 |
2009-12-23 |
Guy S And St Thomas S Nhs Foun |
compositions for immunising against staphylococcus aureus
|
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(en)
|
2010-04-13 |
2013-02-20 |
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|
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(ko)
|
2010-05-28 |
2013-11-06 |
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상호작용 혼성 비동기 컴퓨터 게임 기반구조
|
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(en)
|
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OMV vaccines
|
US9192661B2
(en)
|
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2015-11-24 |
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Delivery of self-replicating RNA using biodegradable polymer particles
|
AR082418A1
(es)
|
2010-08-02 |
2012-12-05 |
Novartis Ag |
Formas cristalinas de 1-(4-metil-5-[2-(2,2,2-trifluoro-1,1-dimetil-etil)-piridin-4-il]-tiazol-2-il)-amida de 2-amida del acido (s)-pirrolidin-1,2-dicarboxilico
|
HUE033901T2
(en)
|
2010-08-17 |
2018-01-29 |
3M Innovative Properties Co |
Formulations and formulations for lipidized immune response modifying compounds and related processes
|
SI2667892T1
(sl)
|
2011-01-26 |
2019-05-31 |
Glaxosmithkline Biologicals Sa |
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|
AP2013007043A0
(en)
|
2011-01-31 |
2013-08-31 |
Novartis Ag |
Novel heterocyclic derivatives
|
ES2651143T3
(es)
|
2011-05-13 |
2018-01-24 |
Glaxosmithkline Biologicals Sa |
Antígenos de F de prefusión del VRS
|
BR112013031039B1
(pt)
|
2011-06-03 |
2020-04-28 |
3M Innovative Properties Co |
compostos de hidrazino 1h-imidazoquinolina-4-aminas, conjugados feitos destes compostos, composição e composição farmacêutica compreendendo ditos compostos e conjugados, usos dos mesmos e método de fabricação do conjugado
|
JP6460789B2
(ja)
|
2011-06-03 |
2019-01-30 |
スリーエム イノベイティブ プロパティズ カンパニー |
ポリエチレングリコールセグメントを有するヘテロ2官能性リンカー及び該リンカーから調製された免疫反応調節複合体
|
WO2013006838A1
(en)
|
2011-07-06 |
2013-01-10 |
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Immunogenic combination compositions and uses thereof
|
EP2729168A2
(en)
|
2011-07-06 |
2014-05-14 |
Novartis AG |
Immunogenic compositions and uses thereof
|
US20130023736A1
(en)
|
2011-07-21 |
2013-01-24 |
Stanley Dale Harpstead |
Systems for drug delivery and monitoring
|
WO2013061305A1
(en)
|
2011-10-28 |
2013-05-02 |
Novartis Ag |
Novel purine derivatives and their use in the treatment of disease
|
CN104080479B
(zh)
|
2011-11-07 |
2019-11-05 |
葛兰素史密丝克莱恩生物有限公司 |
包括spr0096和spr2021抗原的运载体分子
|
WO2013108272A2
(en)
|
2012-01-20 |
2013-07-25 |
International Centre For Genetic Engineering And Biotechnology |
Blood stage malaria vaccine
|
DK2844282T3
(da)
|
2012-05-04 |
2019-07-15 |
Pfizer |
Prostata-associerede antigener og vaccine-baserede immunterapiregimener
|
JP6381523B2
(ja)
|
2012-05-16 |
2018-08-29 |
ノバルティス アーゲー |
Pi−3キナーゼ阻害剤の投与レジメン
|
WO2014005958A1
(en)
|
2012-07-06 |
2014-01-09 |
Novartis Ag |
Immunogenic compositions and uses thereof
|
MX2015008773A
(es)
|
2013-01-07 |
2015-11-06 |
Univ Pennsylvania |
Composiciones y metodos para tratar linfoma cutaneo de celulas t.
|
US9919029B2
(en)
|
2013-07-26 |
2018-03-20 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Methods and pharmaceutical compositions for the treatment of bacterial infections
|
US10471139B2
(en)
*
|
2013-08-15 |
2019-11-12 |
The University Of Kansas |
Toll-like receptor agonists
|
SG11201601542SA
(en)
|
2013-08-16 |
2016-04-28 |
Sloan Kettering Inst Cancer |
Selective grp94 inhibitors and uses thereof
|
CN105873587B
(zh)
|
2013-11-05 |
2020-07-21 |
3M创新有限公司 |
基于芝麻油的注射配制品
|
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(en)
|
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2015-05-13 |
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Salmonella conjugate vaccines
|
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(ja)
|
2013-12-06 |
2016-12-15 |
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|
WO2015108595A1
(en)
|
2014-01-15 |
2015-07-23 |
Nikolai Khodarev |
Anti-tumor therapy
|
ES2769647T3
(es)
|
2014-03-26 |
2020-06-26 |
Glaxosmithkline Biologicals Sa |
Antígenos estafilocócicos mutantes
|
US10286065B2
(en)
|
2014-09-19 |
2019-05-14 |
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Compositions and methods for treating viral infections through stimulated innate immunity in combination with antiviral compounds
|
CN107922416B
(zh)
|
2015-08-31 |
2021-07-02 |
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含有取代的胍基团的咪唑并[4,5-c]环化合物
|
WO2017040233A1
(en)
|
2015-08-31 |
2017-03-09 |
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GUANIDINE SUBSTITUTED IMIDAZO[4,5-c] RING COMPOUNDS
|
WO2017059280A1
(en)
|
2015-10-02 |
2017-04-06 |
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Novel pan-tam inhibitors and mer/axl dual inhibitors
|
AU2016347881A1
(en)
|
2015-11-02 |
2018-05-10 |
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|
KR102392974B1
(ko)
|
2016-05-16 |
2022-05-02 |
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|
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(ja)
|
2016-05-16 |
2022-12-23 |
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|
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(en)
|
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2022-04-06 |
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|
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(ko)
|
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2023-02-10 |
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약물 전달 조성물 및 그의 용도
|
WO2018060833A1
(en)
|
2016-09-27 |
2018-04-05 |
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|
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(en)
|
2016-11-09 |
2018-05-17 |
The Board Of Regents Of The University Of Texas System |
Methods and compositions for adaptive immune modulation
|
WO2018160552A1
(en)
|
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2018-09-07 |
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|
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(es)
|
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2019-08-14 |
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|
WO2019040491A1
(en)
|
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2019-02-28 |
Dynavax Technologies Corporation |
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|
US10722591B2
(en)
|
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2020-07-28 |
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Cleavable conjugates of TLR7/8 agonist compounds, methods for preparation, and uses thereof
|
EP3728255B1
(en)
|
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Amide substituted imidazo[4,5-c]quinoline compounds with a branched chain linking group for use as an immune response modifier
|
US11370788B2
(en)
|
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2022-06-28 |
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Substituted imidazo[4,5-c]quinoline compounds with an N-1 branched group
|
CA3034912A1
(en)
|
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2019-08-28 |
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Il-15 variants and uses thereof
|
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(zh)
|
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2023-02-21 |
美商輝瑞大藥廠 |
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|
EP3796983A2
(en)
|
2018-05-23 |
2021-03-31 |
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Antibodies specific for gucy2c and uses thereof
|
CN112218864B
(zh)
|
2018-05-24 |
2023-09-08 |
3M创新有限公司 |
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|
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(en)
|
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2021-10-06 |
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N-1 branched alkyl ether substituted imidazo[4,5-c]quinoline compounds, compositions, and methods
|
US20220370606A1
(en)
|
2018-12-21 |
2022-11-24 |
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Combination Treatments Of Cancer Comprising A TLR Agonist
|
CN113924297A
(zh)
|
2019-06-06 |
2022-01-11 |
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|
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(zh)
|
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|
US11339159B2
(en)
|
2019-07-17 |
2022-05-24 |
Pfizer Inc. |
Toll-like receptor agonists
|
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(en)
|
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2021-06-17 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of tlr7 and/or tlr8 agonists for the treatment of leptospirosis
|
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(en)
|
2019-12-17 |
2022-08-01 |
Pfizer |
Antibodies unique to d47, pd-l1 and their uses
|
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(en)
|
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Lhc165 and spartalizumab combinations for treating solid tumors
|
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(zh)
|
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|