DE3560313D1 - Improvements in or relating to anticonvulsant agents - Google Patents

Improvements in or relating to anticonvulsant agents

Info

Publication number
DE3560313D1
DE3560313D1 DE8585302418T DE3560313T DE3560313D1 DE 3560313 D1 DE3560313 D1 DE 3560313D1 DE 8585302418 T DE8585302418 T DE 8585302418T DE 3560313 T DE3560313 T DE 3560313T DE 3560313 D1 DE3560313 D1 DE 3560313D1
Authority
DE
Germany
Prior art keywords
relating
anticonvulsant agents
anticonvulsant
agents
pharmaceutical formulations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8585302418T
Other languages
German (de)
Inventor
David Wayne Robertson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of DE3560313D1 publication Critical patent/DE3560313D1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/22—Separation; Purification; Stabilisation; Use of additives
    • C07C231/24—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C233/65—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals

Abstract

This invention provides certain benzamide derivatives, their pharmaceutical formulations and their use as anticonvulsant agents.
DE8585302418T 1984-04-10 1985-04-04 Improvements in or relating to anticonvulsant agents Expired DE3560313D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/598,569 US4629740A (en) 1984-04-10 1984-04-10 Anticonvulsant agents

Publications (1)

Publication Number Publication Date
DE3560313D1 true DE3560313D1 (en) 1987-08-13

Family

ID=24396093

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585302418T Expired DE3560313D1 (en) 1984-04-10 1985-04-04 Improvements in or relating to anticonvulsant agents

Country Status (14)

Country Link
US (1) US4629740A (en)
EP (1) EP0158526B1 (en)
JP (1) JPS60228447A (en)
KR (1) KR850008664A (en)
AT (1) ATE28188T1 (en)
AU (1) AU4084685A (en)
CA (1) CA1253881A (en)
DE (1) DE3560313D1 (en)
DK (1) DK151685A (en)
ES (1) ES8607217A1 (en)
GR (1) GR850831B (en)
HU (1) HUT41002A (en)
PT (1) PT80221B (en)
ZA (1) ZA852495B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4642379A (en) * 1985-08-30 1987-02-10 Eli Lilly And Company Intermediates for anticonvulsant agents
GB8630594D0 (en) * 1986-12-22 1987-02-04 Exxon Chemical Patents Inc Chemical compositions
US4939163A (en) * 1987-02-18 1990-07-03 Eli Lilly And Company Anticonvulsant agents
US4835181A (en) * 1987-02-18 1989-05-30 Eli Lilly And Company Anticonvulsant agents using cyano dimethylphenyl benzamides
US4981866A (en) * 1987-02-18 1991-01-01 Eli Lilly And Company Anticonvulsant agents
US5496826A (en) * 1994-09-02 1996-03-05 Bristol-Myers Squibb Company Pharmaceutical methods of using heterocyclic derivatives of N-phenylamides
US5659082A (en) * 1995-04-03 1997-08-19 Centaur Pharmaceuticals, Inc. Nitro- and aminobenzamide compounds for neurodegenerative disorders
US5643965A (en) * 1995-04-03 1997-07-01 Centaur Pharmaceuticals, Inc. Aminobenzamide compounds for the treatment of neurodegenerative disorders
DE19729640A1 (en) * 1996-08-17 1998-02-19 Ciba Geigy Ag Process for the preparation of nitrobenzamides or aminobenzamides

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4379165A (en) * 1981-05-18 1983-04-05 Research Corporation Anti-convulsant

Also Published As

Publication number Publication date
KR850008664A (en) 1985-12-21
EP0158526B1 (en) 1987-07-08
GR850831B (en) 1985-11-25
CA1253881A (en) 1989-05-09
DK151685A (en) 1985-10-11
ATE28188T1 (en) 1987-07-15
PT80221B (en) 1987-02-17
ES542061A0 (en) 1986-06-16
ZA852495B (en) 1986-11-26
HUT41002A (en) 1987-03-30
US4629740A (en) 1986-12-16
EP0158526A1 (en) 1985-10-16
DK151685D0 (en) 1985-04-03
ES8607217A1 (en) 1986-06-16
JPS60228447A (en) 1985-11-13
AU4084685A (en) 1985-10-17
PT80221A (en) 1985-05-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Free format text: SPOTT, G., DIPL.-CHEM. DR.RER.NAT., PAT.-ANW., 8000 MUENCHEN

8339 Ceased/non-payment of the annual fee