DK0604552T3 - Fremgangsmåde til syntese af forskellige samlinger af oligomerer - Google Patents

Fremgangsmåde til syntese af forskellige samlinger af oligomerer

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Publication number
DK0604552T3
DK0604552T3 DK92920422.0T DK92920422T DK0604552T3 DK 0604552 T3 DK0604552 T3 DK 0604552T3 DK 92920422 T DK92920422 T DK 92920422T DK 0604552 T3 DK0604552 T3 DK 0604552T3
Authority
DK
Denmark
Prior art keywords
synthesis
oligomers
component
different assemblies
compounds
Prior art date
Application number
DK92920422.0T
Other languages
Danish (da)
English (en)
Inventor
Ronald W Barrett
William J Dower
Mark A Gallop
Michael C Needels
Original Assignee
Affymax Tech Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25065309&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0604552(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Affymax Tech Nv filed Critical Affymax Tech Nv
Application granted granted Critical
Publication of DK0604552T3 publication Critical patent/DK0604552T3/da

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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047Simultaneous synthesis of different peptide species; Peptide libraries
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • BPERFORMING OPERATIONS; TRANSPORTING
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    • B01J19/0093Microreactors, e.g. miniaturised or microfabricated reactors
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    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals
    • C07H19/10Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
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    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/14Pyrrolo-pyrimidine radicals
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    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/14Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333Saccharide [e.g., DNA, etc.]

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  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Electric Double-Layer Capacitors Or The Like (AREA)
  • Steroid Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DK92920422.0T 1991-09-18 1992-09-16 Fremgangsmåde til syntese af forskellige samlinger af oligomerer DK0604552T3 (da)

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US76252291A 1991-09-18 1991-09-18

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DK0604552T3 true DK0604552T3 (da) 1997-08-04

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US (7) US5770358A (fr)
EP (2) EP0773227A1 (fr)
JP (1) JP2001524926A (fr)
AT (1) ATE148889T1 (fr)
AU (1) AU669489B2 (fr)
CA (1) CA2118806A1 (fr)
DE (1) DE69217497T2 (fr)
DK (1) DK0604552T3 (fr)
ES (1) ES2097925T3 (fr)
GR (1) GR3023156T3 (fr)
WO (1) WO1993006121A1 (fr)

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US5789162A (en) 1998-08-04
DE69217497T2 (de) 1997-06-12
US5708153A (en) 1998-01-13
EP0604552A4 (fr) 1993-08-02
US6143497A (en) 2000-11-07
EP0773227A1 (fr) 1997-05-14
EP0604552A1 (fr) 1994-07-06
CA2118806A1 (fr) 1993-04-01
US6165717A (en) 2000-12-26
AU2661992A (en) 1993-04-27
GR3023156T3 (en) 1997-07-30
WO1993006121A1 (fr) 1993-04-01
AU669489B2 (en) 1996-06-13
US6140493A (en) 2000-10-31
DE69217497D1 (de) 1997-03-27
US6416949B1 (en) 2002-07-09
ES2097925T3 (es) 1997-04-16
ATE148889T1 (de) 1997-02-15
US5770358A (en) 1998-06-23
JP2001524926A (ja) 2001-12-04
EP0604552B1 (fr) 1997-02-12

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