MX363806B - Funcionalización de superficies sin catalizador e injerto de polímeros.. - Google Patents

Funcionalización de superficies sin catalizador e injerto de polímeros..

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Publication number
MX363806B
MX363806B MX2015018049A MX2015018049A MX363806B MX 363806 B MX363806 B MX 363806B MX 2015018049 A MX2015018049 A MX 2015018049A MX 2015018049 A MX2015018049 A MX 2015018049A MX 363806 B MX363806 B MX 363806B
Authority
MX
Mexico
Prior art keywords
silane
optionally substituted
catalyst
free surface
surface functionalization
Prior art date
Application number
MX2015018049A
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English (en)
Other versions
MX2015018049A (es
Inventor
Berti Lorenzo
A Brown Andrew
N George Wayne
Original Assignee
Illumina Inc
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Filing date
Publication date
Application filed by Illumina Inc filed Critical Illumina Inc
Publication of MX2015018049A publication Critical patent/MX2015018049A/es
Publication of MX363806B publication Critical patent/MX363806B/es

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    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J7/00Chemical treatment or coating of shaped articles made of macromolecular substances
    • C08J7/12Chemical modification
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B32LAYERED PRODUCTS
    • B32BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00Layered products comprising a layer of synthetic resin
    • B32B27/28Layered products comprising a layer of synthetic resin comprising synthetic resins not wholly covered by any one of the sub-groups B32B27/30 - B32B27/42
    • B32B27/283Layered products comprising a layer of synthetic resin comprising synthetic resins not wholly covered by any one of the sub-groups B32B27/30 - B32B27/42 comprising polysiloxanes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B32LAYERED PRODUCTS
    • B32BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B7/00Layered products characterised by the relation between layers; Layered products characterised by the relative orientation of features between layers, or by the relative values of a measurable parameter between layers, i.e. products comprising layers having different physical, chemical or physicochemical properties; Layered products characterised by the interconnection of layers
    • B32B7/04Interconnection of layers
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    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
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    • C09D133/00Coating compositions based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Coating compositions based on derivatives of such polymers
    • C09D133/24Homopolymers or copolymers of amides or imides
    • C09D133/26Homopolymers or copolymers of acrylamide or methacrylamide
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6834Enzymatic or biochemical coupling of nucleic acids to a solid phase
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    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
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    • B01J2219/00527Sheets
    • B01J2219/00529DNA chips
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    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
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    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00605Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00614Delimitation of the attachment areas
    • B01J2219/00617Delimitation of the attachment areas by chemical means
    • B01J2219/00619Delimitation of the attachment areas by chemical means using hydrophilic or hydrophobic regions
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    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00605Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00623Immobilisation or binding
    • B01J2219/00626Covalent
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    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00605Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00632Introduction of reactive groups to the surface
    • B01J2219/00637Introduction of reactive groups to the surface by coating it with another layer
    • BPERFORMING OPERATIONS; TRANSPORTING
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    • C08F220/00Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/52Amides or imides
    • C08F220/54Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • C08F220/60Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide containing nitrogen in addition to the carbonamido nitrogen
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    • C08J2335/00Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical, and containing at least one other carboxyl radical in the molecule, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Derivatives of such polymers
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    • C12Q2565/00Nucleic acid analysis characterised by mode or means of detection
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    • C12Q2565/00Nucleic acid analysis characterised by mode or means of detection
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    • C12Q2565/629Detection means characterised by use of a special device being a microfluidic device

Abstract

La presente invención se refiere a un substrato con una superficie que comprende un silano o un derivado de silano unido covalentemente a un cicloalqueno opcionalmente sustituido o heterociclocalqueno opcionalmente sustituido para conjugación directa con una molécula funcionalizada de interés, tal como un polímero, un hidrogel, o un aminoácido, un nucleósido, un nucleótido, un péptido, un polinucleótido, o una proteína. En algunas modalidades, el silano o derivado de silano contiene norborneno opcionalmente sustituido o derivados de norborneno. También se describe un método para preparar una superficie funcionalizada y el uso en la secuenciación de ADN y otras aplicaciones de diagnóstico.
MX2015018049A 2013-07-01 2014-06-26 Funcionalización de superficies sin catalizador e injerto de polímeros.. MX363806B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361841647P 2013-07-01 2013-07-01
US201461971381P 2014-03-27 2014-03-27
PCT/US2014/044356 WO2015002813A1 (en) 2013-07-01 2014-06-26 Catalyst-free surface functionalization and polymer grafting

Publications (2)

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MX2015018049A MX2015018049A (es) 2016-06-24
MX363806B true MX363806B (es) 2019-04-03

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US (4) US9994687B2 (es)
EP (3) EP3919624A3 (es)
JP (3) JP6511046B2 (es)
KR (3) KR102266002B1 (es)
CN (2) CN105431554B (es)
AU (3) AU2014284584B2 (es)
CA (1) CA2915598C (es)
DK (2) DK3431614T3 (es)
ES (2) ES2700529T3 (es)
HK (1) HK1223655A1 (es)
HU (1) HUE041318T2 (es)
IL (2) IL273519B2 (es)
MX (1) MX363806B (es)
PL (2) PL3017065T3 (es)
PT (1) PT3017065T (es)
TR (1) TR201816438T4 (es)
WO (1) WO2015002813A1 (es)

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