MX2009009127A - Unión de moléculas a nanopartículas. - Google Patents

Unión de moléculas a nanopartículas.

Info

Publication number
MX2009009127A
MX2009009127A MX2009009127A MX2009009127A MX2009009127A MX 2009009127 A MX2009009127 A MX 2009009127A MX 2009009127 A MX2009009127 A MX 2009009127A MX 2009009127 A MX2009009127 A MX 2009009127A MX 2009009127 A MX2009009127 A MX 2009009127A
Authority
MX
Mexico
Prior art keywords
molecule
disclosed
nanoparticles
methods
attached
Prior art date
Application number
MX2009009127A
Other languages
English (en)
Inventor
Chad A Mirkin
Robert Elghanian
Original Assignee
Univ Northwestern
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Northwestern filed Critical Univ Northwestern
Publication of MX2009009127A publication Critical patent/MX2009009127A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/5432—Liposomes or microcapsules

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Se exponen nanopartículas de molécula modificada y métodos para producir y utilizar la misma. Más específicamente, se exponen nanopartículas de molécula modificada en donde la molécula está unida a la superficie de la nanopartícula vía un oligonucleótido. También se exponen los métodos para preparar nanopartículas que tienen oligonucleótidos y moléculas (por ejemplo, biomoléculas, tales como, proteínas, péptidos, anticuerpos, lípidos, y/o carbohidratos) unidos a la superficie de nanopartículas, en donde el oligonucleótido y molécula se unen covalentemente. Además se exponen los métodos para detectar un analito de interés utilizando las nanopartículas de molécula modificada expuestas.
MX2009009127A 2007-02-27 2008-02-27 Unión de moléculas a nanopartículas. MX2009009127A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90372807P 2007-02-27 2007-02-27
PCT/US2008/055133 WO2008127789A2 (en) 2007-02-27 2008-02-27 Molecule attachment to nanoparticles

Publications (1)

Publication Number Publication Date
MX2009009127A true MX2009009127A (es) 2009-10-19

Family

ID=39864611

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009009127A MX2009009127A (es) 2007-02-27 2008-02-27 Unión de moléculas a nanopartículas.

Country Status (7)

Country Link
US (1) US20100167290A1 (es)
EP (1) EP2129803A4 (es)
JP (1) JP2010520749A (es)
AU (1) AU2008239495A1 (es)
CA (1) CA2679586A1 (es)
MX (1) MX2009009127A (es)
WO (1) WO2008127789A2 (es)

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US20150298091A1 (en) 2014-04-21 2015-10-22 President And Fellows Of Harvard College Systems and methods for barcoding nucleic acids
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KR20170063949A (ko) 2014-10-06 2017-06-08 엑시큐어, 인크. 항-ｔｎｆ 화합물
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WO2016168584A1 (en) 2015-04-17 2016-10-20 President And Fellows Of Harvard College Barcoding systems and methods for gene sequencing and other applications
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JP7186094B2 (ja) 2016-05-06 2022-12-08 イグジキュア オペレーティング カンパニー インターロイキン１７受容体ｍＲＮＡの特異的ノックダウンのためのアンチセンスオリゴヌクレオチド（ＡＳＯ）を提示するリポソーム系球状核酸（ＳＮＡ）構築物
US11364304B2 (en) 2016-08-25 2022-06-21 Northwestern University Crosslinked micellar spherical nucleic acids
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Also Published As

Publication number Publication date
WO2008127789A3 (en) 2009-02-19
US20100167290A1 (en) 2010-07-01
CA2679586A1 (en) 2008-10-23
JP2010520749A (ja) 2010-06-17
EP2129803A4 (en) 2010-11-03
EP2129803A2 (en) 2009-12-09
WO2008127789A2 (en) 2008-10-23
AU2008239495A1 (en) 2008-10-23

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