DE602007011787D1 - Membranproteinimmobilisierung auf einem träger mit einem amphiphilen molekül - Google Patents

Membranproteinimmobilisierung auf einem träger mit einem amphiphilen molekül

Info

Publication number
DE602007011787D1
DE602007011787D1 DE602007011787T DE602007011787T DE602007011787D1 DE 602007011787 D1 DE602007011787 D1 DE 602007011787D1 DE 602007011787 T DE602007011787 T DE 602007011787T DE 602007011787 T DE602007011787 T DE 602007011787T DE 602007011787 D1 DE602007011787 D1 DE 602007011787D1
Authority
DE
Germany
Prior art keywords
membrane protein
support
molecule
amphiphilic molecule
amphiphilen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602007011787T
Other languages
English (en)
Inventor
Jean-Luc Popot
Delphine Charvolin
Fabrice Giusti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Universite Paris Diderot Paris 7
Original Assignee
Centre National de la Recherche Scientifique CNRS
Universite Paris Diderot Paris 7
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS, Universite Paris Diderot Paris 7 filed Critical Centre National de la Recherche Scientifique CNRS
Publication of DE602007011787D1 publication Critical patent/DE602007011787D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/02—Peptides being immobilised on, or in, an organic carrier
    • C07K17/06—Peptides being immobilised on, or in, an organic carrier attached to the carrier via a bridging agent

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicinal Preparation (AREA)
DE602007011787T 2006-11-13 2007-11-13 Membranproteinimmobilisierung auf einem träger mit einem amphiphilen molekül Active DE602007011787D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0609882A FR2908414B1 (fr) 2006-11-13 2006-11-13 Immobilisation de proteines membranaires sur un support par l'intermediaire d'une molecule amphiphile
PCT/EP2007/062277 WO2008058963A1 (fr) 2006-11-13 2007-11-13 Immobilisation de proteines membranaires sur un support par l'intermediaire d'une molecule amphiphile

Publications (1)

Publication Number Publication Date
DE602007011787D1 true DE602007011787D1 (de) 2011-02-17

Family

ID=38134638

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602007011787T Active DE602007011787D1 (de) 2006-11-13 2007-11-13 Membranproteinimmobilisierung auf einem träger mit einem amphiphilen molekül

Country Status (8)

Country Link
US (2) US8207263B2 (de)
EP (1) EP2069385B1 (de)
JP (1) JP5684476B2 (de)
AT (1) ATE494297T1 (de)
CA (1) CA2668906C (de)
DE (1) DE602007011787D1 (de)
FR (1) FR2908414B1 (de)
WO (1) WO2008058963A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009157209A1 (ja) 2008-06-27 2009-12-30 株式会社バイオベルデ 細胞および組織の凍結保存用組成物
EP2161020A1 (de) 2008-09-09 2010-03-10 Koninklijke Philips Electronics N.V. Chelatbildende amphiphile Polymere
WO2010064146A2 (en) 2008-12-02 2010-06-10 Chiralgen, Ltd. Method for the synthesis of phosphorus atom modified nucleic acids
KR101885383B1 (ko) 2009-07-06 2018-08-03 웨이브 라이프 사이언시스 리미티드 신규한 핵산 프로드러그 및 그의 사용 방법
FR2952642B1 (fr) 2009-11-16 2012-01-06 Centre Nat Rech Scient Polymeres comprenant une majorite de monomeres amphiphiles destines au piegeage et a la manipulation de proteines membranaires
WO2012050646A2 (en) * 2010-06-29 2012-04-19 The Trustees Of The University Of Pennsylvania Biomimetic chemical sensors using nanoelectronic readout of olfactory receptors
EP2620428B1 (de) 2010-09-24 2019-05-22 Wave Life Sciences Ltd. Asymmetrische hilfsgruppe
GB201110272D0 (en) 2011-06-17 2011-08-03 Isis Innovation Metod of detection by mass spectrometry
JP2013011464A (ja) * 2011-06-28 2013-01-17 Konica Minolta Advanced Layers Inc リガンド固定化方法
JP6128529B2 (ja) 2011-07-19 2017-05-17 ウェイブ ライフ サイエンシズ リミテッドＷａｖｅ Ｌｉｆｅ Ｓｃｉｅｎｃｅｓ Ｌｔｄ． 官能化核酸の合成のための方法
US10983117B2 (en) 2011-08-31 2021-04-20 The Trustees Of The University Of Pennsylvania Carbon nanotube biosensors and related methods
SG11201406160QA (en) * 2012-03-30 2014-11-27 Junichiro Futami Method for producing reagent for antibody detection and use thereof
DK2872485T3 (da) 2012-07-13 2021-03-08 Wave Life Sciences Ltd Asymmetrisk hjælpegruppe
CA2879066C (en) 2012-07-13 2019-08-13 Shin Nippon Biomedical Laboratories, Ltd. Chiral nucleic acid adjuvant
JP6453212B2 (ja) 2012-07-13 2019-01-16 ウェイブ ライフ サイエンシズ リミテッドＷａｖｅ Ｌｉｆｅ Ｓｃｉｅｎｃｅｓ Ｌｔｄ． キラル制御
JP6327662B2 (ja) * 2012-09-26 2018-05-23 学校法人藤田学園 細胞表面タンパクを抗原とする抗体を測定する方法
US10086093B2 (en) 2013-02-28 2018-10-02 The General Hospital Corporation miRNA profiling compositions and methods of use
WO2014150633A1 (en) * 2013-03-15 2014-09-25 Merck Sharp & Dohme Corp. Immobilized ketoreductases and process for making and using immobilized ketoreductase
GB201400562D0 (en) 2014-01-14 2014-03-05 Orla Protein Technologies Ltd Protein coated polymeric substrate
WO2015108046A1 (ja) 2014-01-15 2015-07-23 株式会社新日本科学 抗アレルギー作用を有するキラル核酸アジュバンド及び抗アレルギー剤
WO2015108047A1 (ja) 2014-01-15 2015-07-23 株式会社新日本科学 免疫誘導活性を有するキラル核酸アジュバンド及び免疫誘導活性剤
EP3095459A4 (de) 2014-01-15 2017-08-23 Shin Nippon Biomedical Laboratories, Ltd. Chirales nukleinsäureadjuvans mit antitumorwirkung und antitumormittel
SG10201912897UA (en) 2014-01-16 2020-02-27 Wave Life Sciences Ltd Chiral design
US11415546B2 (en) 2014-09-05 2022-08-16 The Trustees Of The University Of Pennsylvania Volatile organic compound-based diagnostic systems and methods
FR3045834B1 (fr) 2015-12-21 2021-03-05 Biomerieux Sa Diluant de reactifs pour immunoessai
US11255810B2 (en) 2017-09-14 2022-02-22 Siemens Healthcare Diagnostics Inc. Adhesive-polymer containing membranes for in vitro diagnostic devices
JP2022164255A (ja) * 2021-04-16 2022-10-27 住友ゴム工業株式会社 膜タンパク質複合体由来タンパク質を精製する方法
WO2023056960A1 (en) * 2021-10-09 2023-04-13 Nanjing University Single molecule identification with a reactive hetero-nanopore
WO2024121071A1 (en) * 2022-12-05 2024-06-13 Cube Biotech Gmbh Functionalized and non-functionalized amphiphilic polymers based on polyacrylic acid for the solubilization, isolation and molecular labelling of membrane proteins in aqueous media

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4193983A (en) * 1978-05-16 1980-03-18 Syva Company Labeled liposome particle compositions and immunoassays therewith
US5393527A (en) * 1993-01-04 1995-02-28 Becton, Dickinson And Company Stabilized microspheres and methods of preparation
US20050181976A1 (en) * 1993-05-10 2005-08-18 Ekwuribe Nnochiri N. Amphiphilic oligomers
DE69633742T2 (de) * 1996-12-16 2005-11-03 Centre National De La Recherche Scientifique Wasserlöslicher komplex aus membranproteinamphiphile acrylpolymer und verwendung zur diagnose
US7226966B2 (en) * 2001-08-03 2007-06-05 Nanogram Corporation Structures incorporating polymer-inorganic particle blends
DE19814775C2 (de) * 1998-04-02 2001-04-19 Nimbus Biotechnologie Gmbh Verfahren zur Bestimmung der Lipid-Bindungskonstanten von Substanzen in wässriger Lösung an Oberflächen aus amphiphilen Molekülen
KR100314496B1 (ko) * 1998-05-28 2001-11-22 윤동진 항혈전성이 있는 헤파린 유도체, 그의 제조방법 및 용도
US6703381B1 (en) * 1998-08-14 2004-03-09 Nobex Corporation Methods for delivery therapeutic compounds across the blood-brain barrier
TW570805B (en) * 1998-09-01 2004-01-11 Hoffmann La Roche Water-soluble pharmaceutical composition in an ionic complex
US6143358A (en) * 1998-10-01 2000-11-07 Nanofilm, Ltd. Hydrophobic thin films on magnesium fluoride surfaces
JP2003531930A (ja) * 2000-04-28 2003-10-28 ユニバーシティ・カレッジ・ダブリン 両親媒性大環状誘導体およびそれらの類似体
PT1352245E (pt) * 2001-01-18 2007-01-31 Univ Newcastle Ventures Ltd Biossensor com proteínas transmembranares ligadas covalentemente
DE60228941D1 (en) * 2001-03-08 2008-10-30 Univ Pennsylvania Faciale amphiphile polymere als antiinfektiöse mittel
AU2003228724A1 (en) * 2002-04-25 2003-11-10 Fatemeh Mojtabai Self-similar ordered microstructural arrays of amphiphilic molecules
JP2005114428A (ja) * 2003-10-03 2005-04-28 Fuji Photo Film Co Ltd 標的検出用基材及びその製造方法
JP2005114576A (ja) * 2003-10-08 2005-04-28 Hitachi Software Eng Co Ltd 両親媒性分子固定化ビーズ、その製造方法、及びキャピラリビーズアレイのビーズ配列方法
WO2005072271A2 (en) * 2004-01-23 2005-08-11 Nanofilm, Ltd. Surface treatment applicator/dispenser
US20050171596A1 (en) * 2004-02-03 2005-08-04 Furst Joseph G. Stents with amphiphilic copolymer coatings
FR2872910B1 (fr) * 2004-07-07 2006-10-13 Nanoraptor Sa Composant optique pour l'observation d'un echantillon nanometrique, systeme comprenant un tel composant, procede d'analyse mettant en oeuvre ce composant, et leurs applications
SE0403092D0 (sv) * 2004-12-20 2004-12-20 Amo Groningen Bv Amphiphilic block copolymers and their use
US20060224095A1 (en) * 2005-04-05 2006-10-05 University Of New Hampshire Biocompatible polymeric vesicles self assembled from triblock copolymers
WO2006113666A2 (en) * 2005-04-19 2006-10-26 Massachusetts Institute Of Technology Amphiphilic polymers and methods of use thereof
WO2007011959A2 (en) * 2005-07-15 2007-01-25 Quintessence Biosciences, Inc. Methods and compositions for extracting membrane proteins
FR2891149B1 (fr) * 2005-09-26 2007-11-30 Biodex Sarl Composition pharmaceutique a action cicatrisante comprenant un derive de dextrane soluble et un facteur de croissance derive des plaquettes.
US20070122443A1 (en) * 2005-11-29 2007-05-31 Narayanan Pallassana V Amphiphilic copolymer compositions
US8101274B2 (en) * 2007-06-11 2012-01-24 Spedden Richard H Solid state membranes with surface-embedded glycosylated amphiphilic molecules and micelles formed therefrom

Also Published As

Publication number Publication date
US20090275066A1 (en) 2009-11-05
WO2008058963A1 (fr) 2008-05-22
CA2668906A1 (fr) 2008-05-22
ATE494297T1 (de) 2011-01-15
CA2668906C (fr) 2017-11-07
US8207263B2 (en) 2012-06-26
FR2908414A1 (fr) 2008-05-16
US8674044B2 (en) 2014-03-18
FR2908414B1 (fr) 2012-01-20
JP5684476B2 (ja) 2015-03-11
EP2069385A1 (de) 2009-06-17
WO2008058963A8 (fr) 2009-09-03
JP2010509602A (ja) 2010-03-25
US20130023026A1 (en) 2013-01-24
EP2069385B1 (de) 2011-01-05

Similar Documents

Publication Publication Date Title
DE602007011787D1 (de) Membranproteinimmobilisierung auf einem träger mit einem amphiphilen molekül
Smith et al. A comprehensive review of the covalent immobilization of biomolecules onto electrospun nanofibers
Saylan et al. Supermacroporous composite cryogels in biomedical applications
Bakhshpour et al. Biomedical applications of polymeric cryogels
EP3919624A3 (de) Katalysatorfreie oberflächenfunktionalisierung und polymerimmobilisierung
MX2009009127A (es) Unión de moléculas a nanopartículas.
Feng et al. Electrospun regenerated cellulose nanofibrous membranes surface-grafted with polymer chains/brushes via the atom transfer radical polymerization method for catalase immobilization
IL189595A0 (en) Hydrogel functionalized with a polymerizable moiety and their uses as biosensors or bioreactors
DE602006004719D1 (de) Verfahren zur herstellung von cellulosesulfat mit verbesserten eigenschaften
Kang et al. Mussel-inspired universal bioconjugation of polydiacetylene liposome for droplet-array biosensors
EA200800160A1 (ru) Композиты восстановленной ионной жидкостью целлюлозы в качестве матриц твёрдых подложек
IN2014CN03680A (de)
WO2009105670A3 (en) Substrates for multiplexed assays and uses thereof
WO2011035001A8 (en) Novel heparin entities and methods of use
UA117216C2 (uk) Пухлиноасоційований пептид та його застосування
GB201320466D0 (en) Cross-linked poly-e-lysine non-particulate support
Yang et al. Synthesis and characterization of ultralow fouling poly (N-acryloyl-glycinamide) brushes
FR2898898B1 (fr) Empreintes moleculaires pour une reconnaissance en milieu aqueux, leurs procedes de preparation et leurs utilisations
ATE519612T1 (de) Verbindungssystem zur verbindung eines tragarms mit achskörper
EA200900685A1 (ru) Самособирающиеся амфифильные полимеры в качестве противовирусных средств
Parisi et al. Smart bandage based on molecularly imprinted polymers (MIPs) for diclofenac controlled release
Bi et al. Construction of a biomimetic surface on microfluidic chips for biofouling resistance
ATE531736T1 (de) Aktivierung von fluorierten trägern mit nicht- metallocen-komplexen auf eisenbasis
Choi et al. Adsorption of hyaluronic acid on solid supports: Role of pH and surface chemistry in thin film self-assembly
EP2765140A3 (de) Cadherin-2 oder Mucin-13 Bindungsmoleküle zur Krebsbehandlung