BR112018007710A2 - genotipagem multialélica de polimorfismos de nucleotídeo único e indels - Google Patents

genotipagem multialélica de polimorfismos de nucleotídeo único e indels

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Publication number
BR112018007710A2
BR112018007710A2 BR112018007710A BR112018007710A BR112018007710A2 BR 112018007710 A2 BR112018007710 A2 BR 112018007710A2 BR 112018007710 A BR112018007710 A BR 112018007710A BR 112018007710 A BR112018007710 A BR 112018007710A BR 112018007710 A2 BR112018007710 A2 BR 112018007710A2
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BR
Brazil
Prior art keywords
genotyping
multiallelic
indels
single nucleotide
nucleotide polymorphisms
Prior art date
Application number
BR112018007710A
Other languages
English (en)
Other versions
BR112018007710B1 (pt
Inventor
Black Deborah
Oliver Dorothy
Siddiqui Farooq
Nathan Gollub Jeremy
H Shapero Michael
Original Assignee
Affymetrix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Affymetrix Inc filed Critical Affymetrix Inc
Publication of BR112018007710A2 publication Critical patent/BR112018007710A2/pt
Publication of BR112018007710B1 publication Critical patent/BR112018007710B1/pt

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    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
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    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
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    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
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    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/20—Polymerase chain reaction [PCR]; Primer or probe design; Probe optimisation
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    • C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
    • C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
    • C12Q2537/143—Multiplexing, i.e. use of multiple primers or probes in a single reaction, usually for simultaneously analyse of multiple analysis
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    • C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
    • C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
    • C12Q2537/165—Mathematical modelling, e.g. logarithm, ratio
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    • C12Q2539/00—Reactions characterised by analysis of gene expression or genome comparison
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    • C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/50—Detection characterised by immobilisation to a surface
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
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  • Proteomics, Peptides & Aminoacids (AREA)
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Abstract

trata-se de métodos e sistemas para métodos baseados em arranjo para genotipar marcadores multialélicos. são também descritos métodos para amplificação de genoma inteiro e pcr multiplex específica para locus para influenciar seletivamente a amplificação para reduzir efeitos de pseudogenes indesejados nos dados resultantes.
BR112018007710-0A 2015-10-18 2016-10-18 Método de análise do genoma BR112018007710B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562243078P 2015-10-18 2015-10-18
US62/243,078 2015-10-18
PCT/US2016/057496 WO2017070096A1 (en) 2015-10-18 2016-10-18 Multiallelic genotyping of single nucleotide polymorphisms and indels

Publications (2)

Publication Number Publication Date
BR112018007710A2 true BR112018007710A2 (pt) 2018-10-23
BR112018007710B1 BR112018007710B1 (pt) 2024-09-17

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Also Published As

Publication number Publication date
EP3362580A4 (en) 2019-03-27
IL258795A (en) 2018-06-28
JP2019500706A (ja) 2019-01-10
IL296418A (en) 2022-11-01
CN108138226B (zh) 2022-02-11
IL258795B (en) 2022-10-01
RU2706203C1 (ru) 2019-11-14
WO2017070096A1 (en) 2017-04-27
EP3901279B1 (en) 2023-05-17
AU2016341845B2 (en) 2022-11-17
AU2016341845A1 (en) 2018-05-10
AU2022259706A1 (en) 2022-11-24
JP6858783B2 (ja) 2021-04-14
EP3901279A1 (en) 2021-10-27
CN108138226A (zh) 2018-06-08
KR20180071299A (ko) 2018-06-27
US20180305748A1 (en) 2018-10-25
IL258795B2 (en) 2023-02-01
EP3362580A1 (en) 2018-08-22
EP3362580B1 (en) 2021-02-17

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B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

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