DK0579939T3 - Phospholipidderivater - Google Patents

Phospholipidderivater

Info

Publication number
DK0579939T3
DK0579939T3 DK93108904T DK93108904T DK0579939T3 DK 0579939 T3 DK0579939 T3 DK 0579939T3 DK 93108904 T DK93108904 T DK 93108904T DK 93108904 T DK93108904 T DK 93108904T DK 0579939 T3 DK0579939 T3 DK 0579939T3
Authority
DK
Denmark
Prior art keywords
phospholipid
medicaments
preparation processes
phospholipid derivatives
processes therefor
Prior art date
Application number
DK93108904T
Other languages
Danish (da)
English (en)
Inventor
Juergen Prof Engel
Wolfgang Dr Schumacher
Gerhard Dr Noessner
Bernhard Dr Kutscher
Peter Dr Hilgard
Jurij Dr Stekar
Original Assignee
Asta Medica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Ag filed Critical Asta Medica Ag
Application granted granted Critical
Publication of DK0579939T3 publication Critical patent/DK0579939T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/10—Phosphatides, e.g. lecithin
    • C07F9/106—Adducts, complexes, salts of phosphatides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/5532—Seven-(or more) membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/572—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576—Six-membered rings
    • C07F9/59—Hydrogenated pyridine rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • AIDS & HIV (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
  • Saccharide Compounds (AREA)
DK93108904T 1992-07-11 1993-06-03 Phospholipidderivater DK0579939T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4222910A DE4222910A1 (de) 1992-07-11 1992-07-11 Neue Phospholipidderivate

Publications (1)

Publication Number Publication Date
DK0579939T3 true DK0579939T3 (da) 1999-09-20

Family

ID=6463031

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93108904T DK0579939T3 (da) 1992-07-11 1993-06-03 Phospholipidderivater

Country Status (31)

Country Link
EP (1) EP0579939B1 (fr)
JP (1) JP3311431B2 (fr)
KR (1) KR100297180B1 (fr)
CN (1) CN1039012C (fr)
AT (1) ATE176477T1 (fr)
AU (1) AU664101B2 (fr)
BR (1) BR9302809A (fr)
CA (2) CA2100228C (fr)
CZ (1) CZ290863B6 (fr)
DE (2) DE4222910A1 (fr)
DK (1) DK0579939T3 (fr)
EE (1) EE03140B1 (fr)
ES (1) ES2129053T3 (fr)
FI (1) FI111262B (fr)
GR (1) GR3029602T3 (fr)
HR (1) HRP931046B1 (fr)
HU (1) HU218783B (fr)
IL (1) IL106289A (fr)
LT (1) LT3113B (fr)
LV (1) LV10870B (fr)
MX (1) MX9304133A (fr)
NO (1) NO306468B1 (fr)
PL (3) PL175607B1 (fr)
RU (1) RU2108336C1 (fr)
SG (1) SG46249A1 (fr)
SI (1) SI9300365B (fr)
SK (1) SK283827B6 (fr)
TW (1) TW304956B (fr)
UA (1) UA40567C2 (fr)
YU (1) YU49079B (fr)
ZA (1) ZA934971B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006077424A1 (fr) 2005-01-21 2006-07-27 Astex Therapeutics Limited Composes pharmaceutiques
JP5232009B2 (ja) 2005-12-19 2013-07-10 エテルナ ツェンタリス ゲゼルシャフト ミット ベシュレンクテル ハフツング 低減された細胞毒性を有するアルキルリン脂質誘導体並びにそれらの使用
EP1800684A1 (fr) * 2005-12-20 2007-06-27 Zentaris GmbH Nouveaux alkylphospholipides et leur utilisation
EP1869981A1 (fr) * 2006-06-21 2007-12-26 Staatliches Weinbauinstitut Freiburg Alkylphospholipides et lysophospholipides pour la lutte contre les phytopathogènes
EP2073803B1 (fr) 2006-10-12 2018-09-19 Astex Therapeutics Limited Combinaisons pharmaceutiques
EP2073807A1 (fr) 2006-10-12 2009-07-01 Astex Therapeutics Limited Combinaisons pharmaceutiques

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4444766A (en) * 1980-10-21 1984-04-24 Boehringer Mannheim Gmbh Sulfur-containing phospholipid compounds and therapeutic compositions
JPS5984824A (ja) * 1982-11-08 1984-05-16 Takeda Chem Ind Ltd 抗腫瘍剤
DE3530767A1 (de) * 1985-08-28 1987-03-12 Max Planck Gesellschaft Mittel gegen multiple sklerose
IE59777B1 (en) * 1985-12-04 1994-04-06 Max Planck Gesellschaft Medicaments
ES2036210T3 (es) * 1986-07-14 1993-05-16 Nippon Chemiphar Co., Ltd. Un procedimiento para la preparacion de un derivado de glicerol.
CN1017435B (zh) * 1987-03-24 1992-07-15 日本化学医药株式会社 新的甘油衍生物的制备方法
DE3906952A1 (de) * 1989-03-04 1990-09-06 Boehringer Mannheim Gmbh (3-(c(pfeil abwaerts)1(pfeil abwaerts)(pfeil abwaerts)6(pfeil abwaerts)-c(pfeil abwaerts)1(pfeil abwaerts)(pfeil abwaerts)8(pfeil abwaerts))alkansulfinyl- und sulfonyl-2-methoxymethyl-propyl)-(2-trimethylammonio-ethyl) phosphate, verfahren zu deren herstellung diese verbindungen enthaltende arzneimittel
DE3942933A1 (de) * 1989-12-23 1991-06-27 Boehringer Mannheim Gmbh Verwendung von alkylphospholipiden als antivirale arzneimittel und neue phospholipid-derivate
DE4114586A1 (de) * 1991-05-04 1992-11-05 Boehringer Mannheim Gmbh Arzneimittel enthaltend azacyclodiphosphonsaeurederivate, neue azacyclodiphosphonsaeurederivate sowie verfahren zu deren herstellung

Also Published As

Publication number Publication date
PL173388B1 (pl) 1998-02-27
CN1039012C (zh) 1998-07-08
JPH0733791A (ja) 1995-02-03
CA2100228C (fr) 2006-01-24
KR100297180B1 (ko) 2001-11-30
EP0579939A1 (fr) 1994-01-26
ZA934971B (en) 1994-02-01
YU47393A (sh) 1997-08-22
TW304956B (fr) 1997-05-11
BR9302809A (pt) 1994-03-15
NO932502L (no) 1994-01-12
CA2511753A1 (fr) 1994-01-12
DE4222910A1 (de) 1994-01-13
AU664101B2 (en) 1995-11-02
RU2108336C1 (ru) 1998-04-10
IL106289A (en) 2000-06-01
LV10870B (en) 1996-06-20
NO932502D0 (no) 1993-07-08
SI9300365B (sl) 2002-02-28
FI933165A0 (fi) 1993-07-09
ES2129053T3 (es) 1999-06-01
CN1084175A (zh) 1994-03-23
NO306468B1 (no) 1999-11-08
CA2511753C (fr) 2007-09-25
HRP931046B1 (en) 2000-06-30
GR3029602T3 (en) 1999-06-30
IL106289A0 (en) 1994-04-12
LV10870A (lv) 1995-10-20
AU4186493A (en) 1994-01-13
PL177811B1 (pl) 2000-01-31
UA40567C2 (uk) 2001-08-15
YU49079B (sh) 2003-08-29
JP3311431B2 (ja) 2002-08-05
HU9301992D0 (en) 1993-09-28
HUT64548A (en) 1994-01-28
SK67093A3 (en) 1995-03-08
SI9300365A (en) 1994-03-31
PL175607B1 (pl) 1999-01-29
CZ290863B6 (cs) 2002-11-13
DE59309355D1 (de) 1999-03-18
HU218783B (hu) 2000-12-28
EE03140B1 (et) 1998-12-15
ATE176477T1 (de) 1999-02-15
HRP931046A2 (en) 1997-04-30
LT3113B (en) 1994-12-27
LTIP620A (en) 1994-07-15
CA2100228A1 (fr) 1994-01-12
FI111262B (fi) 2003-06-30
EP0579939B1 (fr) 1999-02-03
PL299624A1 (en) 1994-02-21
FI933165A (fi) 1994-01-12
KR940002265A (ko) 1994-02-17
SK283827B6 (sk) 2004-02-03
CZ124993A3 (en) 1995-03-15
MX9304133A (es) 1994-04-29
SG46249A1 (en) 1998-02-20

Similar Documents

Publication Publication Date Title
ATE494009T1 (de) Prodrugs, ihre herstellung und verwendung als arzneimittel
PT83872A (de) Arzneimittel
DE68920455D1 (de) Cyclohexenderivate.
DK0579939T3 (da) Phospholipidderivater
DE58902310D1 (de) Tetrahydropyridin-derivate.
IT8622051A1 (it) Composizioni farmaceutiche ad attivita' cicatrizzante
ATE66481T1 (de) Pyranobenzoxadiazolderivate, herstellung, verwendung und diese enthaltende zubereitungen.