DK0536741T3 - Cykliske VIP-analoger - Google Patents

Cykliske VIP-analoger

Info

Publication number
DK0536741T3
DK0536741T3 DK92117185.6T DK92117185T DK0536741T3 DK 0536741 T3 DK0536741 T3 DK 0536741T3 DK 92117185 T DK92117185 T DK 92117185T DK 0536741 T3 DK0536741 T3 DK 0536741T3
Authority
DK
Denmark
Prior art keywords
peptide
amino acid
vasoactive
chain
cyclic
Prior art date
Application number
DK92117185.6T
Other languages
Danish (da)
English (en)
Inventor
David Robert Bolin
Margaret Odonnell
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK0536741T3 publication Critical patent/DK0536741T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57563—Vasoactive intestinal peptide [VIP]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/17—Vasoactive intestinal peptides; related peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/27—Cyclic peptide or cyclic protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK92117185.6T 1991-10-11 1992-10-08 Cykliske VIP-analoger DK0536741T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US77374791A 1991-10-11 1991-10-11

Publications (1)

Publication Number Publication Date
DK0536741T3 true DK0536741T3 (da) 1996-04-22

Family

ID=25099195

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92117185.6T DK0536741T3 (da) 1991-10-11 1992-10-08 Cykliske VIP-analoger

Country Status (26)

Country Link
US (1) US5677419A (ru)
EP (1) EP0536741B1 (ru)
JP (1) JP2515473B2 (ru)
KR (1) KR970001580B1 (ru)
CN (3) CN1034943C (ru)
AT (1) ATE132165T1 (ru)
AU (1) AU656230B2 (ru)
BG (1) BG61125B2 (ru)
BR (1) BR9203959A (ru)
CA (1) CA2080272C (ru)
CZ (1) CZ281818B6 (ru)
DE (1) DE69207138T2 (ru)
DK (1) DK0536741T3 (ru)
ES (1) ES2082317T3 (ru)
FI (2) FI111646B (ru)
GR (1) GR3019326T3 (ru)
HU (2) HUT62606A (ru)
IL (3) IL117252A (ru)
MX (1) MX9205822A (ru)
NO (3) NO304523B1 (ru)
NZ (1) NZ244644A (ru)
RU (1) RU2095368C1 (ru)
SK (1) SK279399B6 (ru)
TW (1) TW305846B (ru)
UY (2) UY23488A1 (ru)
ZA (1) ZA927724B (ru)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6872803B1 (en) 1993-09-21 2005-03-29 Kyowa Hakko Kogyo Co., Ltd. Peptides
KR100493795B1 (ko) * 1996-02-09 2005-09-09 에프. 호프만-라 로슈 아게 혈관활성장펩타이드유사체의합성방법
DE69738353T2 (de) * 1996-07-12 2009-09-24 Immunomedics, Inc. Radiometall-bindende peptide analoge
WO1998002453A2 (en) * 1996-07-15 1998-01-22 Universite Libre De Bruxelles Peptidic ligands having a higher selectivity for the vip1 receptor than for the vip2 receptor
ES2307534T3 (es) * 1999-09-28 2008-12-01 Bayer Corporation Agonistas de receptores 3 (r3) del peptido activador de la adenilato ciclasa hipofisiaria (pacap) y sus metodos de uso farmacologicos.
US6972319B1 (en) 1999-09-28 2005-12-06 Bayer Pharmaceuticals Corporation Pituitary adenylate cyclase activating peptide (PACAP)receptor 3 (R3) agonists and their pharmacological methods of use
DE60033697D1 (de) 2000-02-18 2007-04-12 Dabur Res Foundation Sahibabad Radiomarkierte vip-analoge zur diagnose und therapie
WO2001060862A1 (en) 2000-02-18 2001-08-23 Dabur Research Foundation Vasoactive intestinal peptide analogs
US6828304B1 (en) 2000-07-31 2004-12-07 Dabur Research Foundation Peptides for treatment of cancer
US7507714B2 (en) * 2000-09-27 2009-03-24 Bayer Corporation Pituitary adenylate cyclase activating peptide (PACAP) receptor 3 (R3) agonists and their pharmacological methods of use
CN1487952A (zh) 2000-11-28 2004-04-07 �ɶ����＼��ʵ���� 具有血管活性肠肽的生物学活性的用于治疗肺动脉和小动脉高压的化合物
US20060241028A1 (en) 2002-06-10 2006-10-26 Dorian Bevec Use of compounds having the biological activity of vasoactive intestinal peptide for the treatment of sarcoidosis
AU2005208911A1 (en) * 2004-01-27 2005-08-11 Bayer Healthcare Llc Pituitary adenylate cyclase activating peptide (PACAP) receptor (VPAC2) agonists and their pharmacological methods of use
US20080085860A1 (en) * 2004-08-18 2008-04-10 Eli Lilly And Company Selective Vpac2 Receptor Peptide Agonists
CA2577010A1 (en) * 2004-08-18 2006-03-02 Eli Lilly And Company Selective vpac2 receptor peptide agonists
BRPI0708341A2 (pt) * 2006-02-28 2011-05-24 Lilly Co Eli agonistas peptìdicos seletivos do receptor vpac2
MX2009000013A (es) * 2006-07-06 2009-01-23 Hoffmann La Roche Nuevos analogos del peptido intestinal vasoactivo.
CN101906144B (zh) * 2009-06-03 2013-06-19 首都医科大学 一根Arg-Gly-Asp-Val链通过Asp与两根脂肪醇链的偶联物、它们的合成及在医学中的应用
EP2464370B1 (en) 2009-08-14 2017-03-29 Phasebio Pharmaceuticals, Inc. Modified vasoactive intestinal peptides
WO2011133948A2 (en) * 2010-04-22 2011-10-27 Longevity Biotech, Inc. Highly active polypeptides and methods of making and using the same
CA2873553C (en) 2011-06-06 2020-01-28 Phasebio Pharmaceuticals, Inc. Use of modified vasoactive intestinal peptides in the treatment of hypertension
WO2014145718A2 (en) 2013-03-15 2014-09-18 Longevity Biotech, Inc. Peptides comprising non-natural amino acids and methods of making and using the same
GB201421647D0 (en) * 2014-12-05 2015-01-21 Amcure Gmbh And Ruprecht-Karls-Universitat And Karlsruher Institut F�R Technologie CD44v6-derived cyclic peptides for treating cancers and angiogenesis related diseases
CA2976038A1 (en) 2015-02-09 2016-08-18 Phasebio Pharmaceuticals, Inc. Methods and compositions for treating muscle disease and disorders
JP6892867B2 (ja) 2016-09-30 2021-06-23 富士フイルム株式会社 環状ペプチド、アフィニティクロマトグラフィー担体、標識化抗体、抗体薬物複合体および医薬製剤

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8427651D0 (en) * 1984-11-01 1984-12-05 Beecham Group Plc Compounds
US4835252A (en) * 1987-02-26 1989-05-30 The Salk Institute Biotechnology/Industrial Associates, Inc. Vasoactive intestinal peptide analogs
GB8729802D0 (en) * 1987-12-22 1988-02-03 Beecham Group Plc Novel compounds
US5084442A (en) * 1988-09-06 1992-01-28 Hoffmann-La Roche Inc. Cyclic growth hormone releasing factor analogs and method for the manufacture thereof
US5141924A (en) * 1989-06-30 1992-08-25 Hoffmann-La Roche, Inc. Synthetic vasoactive intestinal peptide analogs

Also Published As

Publication number Publication date
FI924580A (fi) 1993-04-12
CN1225473C (zh) 2005-11-02
NZ244644A (en) 1995-04-27
NO304523B1 (no) 1999-01-04
NO980377D0 (no) 1998-01-28
DE69207138T2 (de) 1996-06-13
GR3019326T3 (en) 1996-06-30
KR970001580B1 (ko) 1997-02-11
MX9205822A (es) 1993-06-01
HUT62606A (en) 1993-05-28
IL103396A (en) 1997-11-20
CN1152579A (zh) 1997-06-25
IL103396A0 (en) 1993-03-15
FI111646B (fi) 2003-08-29
JP2515473B2 (ja) 1996-07-10
DE69207138D1 (de) 1996-02-08
ZA927724B (en) 1994-04-07
CN1034943C (zh) 1997-05-21
SK308692A3 (en) 1995-03-08
NO975023D0 (no) 1997-10-31
FI20002041A (fi) 2000-09-15
NO975023L (no) 1993-04-13
HU9203194D0 (en) 1992-12-28
AU656230B2 (en) 1995-01-27
BG61125B2 (bg) 1996-11-29
HU211534A9 (en) 1995-12-28
BR9203959A (pt) 1993-04-27
UY25084A1 (es) 1998-12-21
CZ308692A3 (en) 1993-08-11
TW305846B (ru) 1997-05-21
EP0536741B1 (en) 1995-12-27
RU2095368C1 (ru) 1997-11-10
US5677419A (en) 1997-10-14
KR930007972A (ko) 1993-05-20
CZ281818B6 (cs) 1997-02-12
SK279399B6 (sk) 1998-11-04
IL117252A0 (en) 1996-06-18
NO980377L (no) 1993-04-13
CA2080272A1 (en) 1993-04-12
ES2082317T3 (es) 1996-03-16
AU2622892A (en) 1993-04-22
NO923929D0 (no) 1992-10-09
CN1153785A (zh) 1997-07-09
JPH05213996A (ja) 1993-08-24
IL117252A (en) 1999-11-30
ATE132165T1 (de) 1996-01-15
CN1072415A (zh) 1993-05-26
FI924580A0 (fi) 1992-10-09
NO923929L (no) 1993-04-13
CN1198841C (zh) 2005-04-27
EP0536741A2 (en) 1993-04-14
EP0536741A3 (ru) 1994-04-06
UY23488A1 (es) 1993-04-20
CA2080272C (en) 2002-09-17

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