DE69930252T2 - Verwendung von tetracyclinen zur behandlung von störungen der meibomschen drüsen - Google Patents
Verwendung von tetracyclinen zur behandlung von störungen der meibomschen drüsen Download PDFInfo
- Publication number
- DE69930252T2 DE69930252T2 DE69930252T DE69930252T DE69930252T2 DE 69930252 T2 DE69930252 T2 DE 69930252T2 DE 69930252 T DE69930252 T DE 69930252T DE 69930252 T DE69930252 T DE 69930252T DE 69930252 T2 DE69930252 T2 DE 69930252T2
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- Prior art keywords
- tetracycline
- antimicrobial
- patients
- tears
- meibomian gland
- Prior art date
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
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- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Ophthalmology & Optometry (AREA)
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- Tropical Medicine & Parasitology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
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| US8487398P | 1998-05-08 | 1998-05-08 | |
| US84873P | 1998-05-08 | ||
| PCT/US1999/009965 WO1999058131A1 (en) | 1998-05-08 | 1999-05-07 | Use of tetracyclines for treating meibomian gland disease |
Publications (2)
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| DE69930252D1 DE69930252D1 (de) | 2006-05-04 |
| DE69930252T2 true DE69930252T2 (de) | 2006-12-14 |
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| DE69940227T Expired - Lifetime DE69940227D1 (de) | 1998-05-08 | 1999-05-07 | Verwendung von sub-antimikrobiellen tetracyclinen zur Behandlung von okularer Rosacea |
| DE69930252T Expired - Lifetime DE69930252T2 (de) | 1998-05-08 | 1999-05-07 | Verwendung von tetracyclinen zur behandlung von störungen der meibomschen drüsen |
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| Application Number | Title | Priority Date | Filing Date |
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| DE69940227T Expired - Lifetime DE69940227D1 (de) | 1998-05-08 | 1999-05-07 | Verwendung von sub-antimikrobiellen tetracyclinen zur Behandlung von okularer Rosacea |
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| US (6) | US6455583B1 (enExample) |
| EP (2) | EP1676579B1 (enExample) |
| JP (1) | JP4860038B2 (enExample) |
| AT (2) | ATE319456T1 (enExample) |
| AU (1) | AU763164B2 (enExample) |
| CA (1) | CA2331257C (enExample) |
| DE (2) | DE69940227D1 (enExample) |
| DK (2) | DK1676579T3 (enExample) |
| ES (2) | ES2260912T3 (enExample) |
| PT (2) | PT1676579E (enExample) |
| TW (2) | TWI255713B (enExample) |
| WO (1) | WO1999058131A1 (enExample) |
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| DK1676579T3 (da) * | 1998-05-08 | 2009-03-16 | Univ Miami | Anvendelse af sub-antimikrobielle tetracykliner til behandling af okulær rosacea |
| US6432934B1 (en) | 1998-08-06 | 2002-08-13 | Advanced Vision Research | Methods and compositions for topical treatment of eye surface inflammation and related dry eye disease |
| US6506740B1 (en) * | 1998-11-18 | 2003-01-14 | Robert A. Ashley | 4-dedimethylaminotetracycline derivatives |
| AU4684000A (en) * | 1999-04-27 | 2000-11-10 | Antibody Systems, Inc. | Compositions containing tetracyclines for treating hemorrhagic virus infections and other disorders |
| US7211267B2 (en) * | 2001-04-05 | 2007-05-01 | Collagenex Pharmaceuticals, Inc. | Methods of treating acne |
| JP2004525955A (ja) * | 2001-04-05 | 2004-08-26 | コッラジェネックス ファーマシューチカルス インコーポレイテッド | テトラサイクリン化合物およびテトラサイクリン誘導体の制御された伝達 |
| EP2332547A1 (en) * | 2001-07-13 | 2011-06-15 | Paratek Pharmaceuticals, Inc. | Tetracyclines for the treatment of inflammatory bowel disease |
| US20030073068A1 (en) * | 2001-10-15 | 2003-04-17 | Campbell Robert Edward | Methods for application of tear-based biomarkers to ophthalmic product evaluation and clinical study management |
| WO2003088906A2 (en) * | 2002-04-16 | 2003-10-30 | Collagenex Pharmaceuticals, Inc. | Methods of simultaneously treating ocular rosacea and acne rosacea |
| US8192749B2 (en) * | 2003-04-16 | 2012-06-05 | Galderma Laboratories Inc. | Methods of simultaneously treating ocular rosacea and acne rosacea |
| JP2005526114A (ja) * | 2002-05-06 | 2005-09-02 | コッラジェネックス ファーマシューチカルス インコーポレイテッド | 粘膜炎及び真菌感染症の同時治療方法 |
| KR20050092429A (ko) * | 2003-01-22 | 2005-09-21 | 니찌방 가부시기가이샤 | 안질환 치료용 경피 흡수형 제제, 그 사용, 및 안질환치료약의 눈의 국소 조직으로의 이행 방법 |
| EP2204168B1 (en) * | 2003-04-07 | 2015-01-14 | Supernus Pharmaceuticals, Inc. | Once daily formulations of tetracyclines |
| US6984628B2 (en) * | 2003-07-15 | 2006-01-10 | Allergan, Inc. | Ophthalmic compositions comprising trefoil factor family peptides |
| WO2005011707A1 (en) * | 2003-07-25 | 2005-02-10 | Warner Chilcott Company, Inc. | A doxycycline metal complex in a solid dosage form |
| WO2007024972A2 (en) * | 2005-08-22 | 2007-03-01 | Quick-Med Technologies, Inc. | Non-leaching absorbent wound dressing |
| CN100340241C (zh) * | 2004-06-28 | 2007-10-03 | 中山大学中山眼科中心 | 一种滴眼液及其制备方法与用途 |
| CA2595481C (en) * | 2005-01-21 | 2014-05-13 | Warner Chilcott Company, Inc. | A tetracycline metal complex in a solid dosage form |
| US7544373B2 (en) * | 2007-04-02 | 2009-06-09 | Medicis Pharmaceutical Corporation | Minocycline oral dosage forms for the treatment of acne |
| US8722650B1 (en) | 2005-06-24 | 2014-05-13 | Medicis Pharmaceutical Corporation | Extended-release minocycline dosage forms |
| US20080242642A1 (en) * | 2007-04-02 | 2008-10-02 | Medicis Pharmaceutical Corporation | Minocycline oral dosage forms for the treatment of acne |
| US8252776B2 (en) | 2007-04-02 | 2012-08-28 | Medicis Pharmaceutical Corporation | Minocycline oral dosage forms for the treatment of acne |
| US20080241235A1 (en) * | 2007-04-02 | 2008-10-02 | Medicis Pharmaceutical Corporation | Minocycline oral dosage forms for the treatment of acne |
| US7541347B2 (en) | 2007-04-02 | 2009-06-02 | Medicis Pharmaceutical Coropration | Minocycline oral dosage forms for the treatment of acne |
| US7919483B2 (en) * | 2005-06-24 | 2011-04-05 | Medicis Pharmaceutical Corporation | Method for the treatment of acne |
| US20080114423A1 (en) * | 2006-05-15 | 2008-05-15 | Grenon Stephen M | Apparatus for inner eyelid treatment of meibomian gland dysfunction |
| US20090043365A1 (en) * | 2005-07-18 | 2009-02-12 | Kolis Scientific, Inc. | Methods, apparatuses, and systems for reducing intraocular pressure as a means of preventing or treating open-angle glaucoma |
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1999
- 1999-05-07 DK DK06004523T patent/DK1676579T3/da active
- 1999-05-07 JP JP2000547982A patent/JP4860038B2/ja not_active Expired - Fee Related
- 1999-05-07 PT PT06004523T patent/PT1676579E/pt unknown
- 1999-05-07 ES ES99921754T patent/ES2260912T3/es not_active Expired - Lifetime
- 1999-05-07 AT AT99921754T patent/ATE319456T1/de active
- 1999-05-07 CA CA2331257A patent/CA2331257C/en not_active Expired - Fee Related
- 1999-05-07 WO PCT/US1999/009965 patent/WO1999058131A1/en not_active Ceased
- 1999-05-07 ES ES06004523T patent/ES2320579T3/es not_active Expired - Lifetime
- 1999-05-07 EP EP06004523A patent/EP1676579B1/en not_active Expired - Lifetime
- 1999-05-07 DK DK99921754T patent/DK1075265T3/da active
- 1999-05-07 AT AT06004523T patent/ATE418989T1/de active
- 1999-05-07 AU AU38879/99A patent/AU763164B2/en not_active Ceased
- 1999-05-07 US US09/307,182 patent/US6455583B1/en not_active Expired - Fee Related
- 1999-05-07 DE DE69940227T patent/DE69940227D1/de not_active Expired - Lifetime
- 1999-05-07 DE DE69930252T patent/DE69930252T2/de not_active Expired - Lifetime
- 1999-05-07 EP EP99921754A patent/EP1075265B1/en not_active Expired - Lifetime
- 1999-05-07 PT PT99921754T patent/PT1075265E/pt unknown
- 1999-05-25 TW TW088107469A patent/TWI255713B/zh not_active IP Right Cessation
- 1999-05-25 TW TW094111310A patent/TWI255714B/zh not_active IP Right Cessation
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2002
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2005
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2007
- 2007-10-11 US US11/974,435 patent/US20080214510A1/en not_active Abandoned
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2010
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| US20030114426A1 (en) | 2003-06-19 |
| ATE418989T1 (de) | 2009-01-15 |
| DK1676579T3 (da) | 2009-03-16 |
| JP2002514602A (ja) | 2002-05-21 |
| AU763164B2 (en) | 2003-07-17 |
| DK1075265T3 (da) | 2006-06-26 |
| EP1075265A1 (en) | 2001-02-14 |
| EP1075265B1 (en) | 2006-03-08 |
| ES2260912T3 (es) | 2006-11-01 |
| EP1676579A3 (en) | 2006-07-12 |
| ES2320579T3 (es) | 2009-05-25 |
| PT1676579E (pt) | 2009-03-24 |
| TW200526232A (en) | 2005-08-16 |
| US20060154901A1 (en) | 2006-07-13 |
| US20120088739A1 (en) | 2012-04-12 |
| CA2331257A1 (en) | 1999-11-18 |
| AU3887999A (en) | 1999-11-29 |
| HK1089696A1 (en) | 2006-12-08 |
| DE69940227D1 (de) | 2009-02-12 |
| ATE319456T1 (de) | 2006-03-15 |
| EP1676579A2 (en) | 2006-07-05 |
| EP1676579B1 (en) | 2008-12-31 |
| DE69930252D1 (de) | 2006-05-04 |
| HK1034899A1 (en) | 2001-11-09 |
| US6455583B1 (en) | 2002-09-24 |
| US20080214510A1 (en) | 2008-09-04 |
| TWI255713B (en) | 2006-06-01 |
| US20110039805A1 (en) | 2011-02-17 |
| TWI255714B (en) | 2006-06-01 |
| JP4860038B2 (ja) | 2012-01-25 |
| PT1075265E (pt) | 2006-07-31 |
| WO1999058131A1 (en) | 1999-11-18 |
| CA2331257C (en) | 2012-01-03 |
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