FR2660193B1 - Produit opthalmique comportant des nanocapsules, son procede de preparation et utilisation des nanocapsules. - Google Patents

Produit opthalmique comportant des nanocapsules, son procede de preparation et utilisation des nanocapsules.

Info

Publication number
FR2660193B1
FR2660193B1 FR9004491A FR9004491A FR2660193B1 FR 2660193 B1 FR2660193 B1 FR 2660193B1 FR 9004491 A FR9004491 A FR 9004491A FR 9004491 A FR9004491 A FR 9004491A FR 2660193 B1 FR2660193 B1 FR 2660193B1
Authority
FR
France
Prior art keywords
nanocapsules
preparation
product
opthalmic
application
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9004491A
Other languages
English (en)
Other versions
FR2660193A1 (fr
Inventor
Philippe Maincent
Laurent Marchal-Heussler
Daniel Sirbat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MARCHEL HEUSSLER LAURENT
Original Assignee
MARCHEL HEUSSLER LAURENT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MARCHEL HEUSSLER LAURENT filed Critical MARCHEL HEUSSLER LAURENT
Priority to FR9004491A priority Critical patent/FR2660193B1/fr
Priority to US07/677,531 priority patent/US5308624A/en
Priority to DK91500033.5T priority patent/DK0451082T3/da
Priority to DE69106560T priority patent/DE69106560T2/de
Priority to ES91500033T priority patent/ES2071275T3/es
Priority to AT91500033T priority patent/ATE116846T1/de
Priority to EP91500033A priority patent/EP0451082B1/fr
Priority to JP3070833A priority patent/JPH0723325B2/ja
Publication of FR2660193A1 publication Critical patent/FR2660193A1/fr
Application granted granted Critical
Publication of FR2660193B1 publication Critical patent/FR2660193B1/fr
Priority to GR950400840T priority patent/GR3015693T3/el
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Virology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Electroluminescent Light Sources (AREA)
FR9004491A 1990-04-03 1990-04-03 Produit opthalmique comportant des nanocapsules, son procede de preparation et utilisation des nanocapsules. Expired - Fee Related FR2660193B1 (fr)

Priority Applications (9)

Application Number Priority Date Filing Date Title
FR9004491A FR2660193B1 (fr) 1990-04-03 1990-04-03 Produit opthalmique comportant des nanocapsules, son procede de preparation et utilisation des nanocapsules.
US07/677,531 US5308624A (en) 1990-04-03 1991-03-29 Ophthalmic product
DE69106560T DE69106560T2 (de) 1990-04-03 1991-04-02 Ophthalmikum.
ES91500033T ES2071275T3 (es) 1990-04-03 1991-04-02 Producto oftalmico.
DK91500033.5T DK0451082T3 (da) 1990-04-03 1991-04-02 Ophthalmisk produkt
AT91500033T ATE116846T1 (de) 1990-04-03 1991-04-02 Ophthalmikum.
EP91500033A EP0451082B1 (fr) 1990-04-03 1991-04-02 Produit ophtalmique
JP3070833A JPH0723325B2 (ja) 1990-04-03 1991-04-03 眼病用製剤
GR950400840T GR3015693T3 (en) 1990-04-03 1995-04-04 Ophthalmic product.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9004491A FR2660193B1 (fr) 1990-04-03 1990-04-03 Produit opthalmique comportant des nanocapsules, son procede de preparation et utilisation des nanocapsules.

Publications (2)

Publication Number Publication Date
FR2660193A1 FR2660193A1 (fr) 1991-10-04
FR2660193B1 true FR2660193B1 (fr) 1994-11-04

Family

ID=9395546

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9004491A Expired - Fee Related FR2660193B1 (fr) 1990-04-03 1990-04-03 Produit opthalmique comportant des nanocapsules, son procede de preparation et utilisation des nanocapsules.

Country Status (9)

Country Link
US (1) US5308624A (fr)
EP (1) EP0451082B1 (fr)
JP (1) JPH0723325B2 (fr)
AT (1) ATE116846T1 (fr)
DE (1) DE69106560T2 (fr)
DK (1) DK0451082T3 (fr)
ES (1) ES2071275T3 (fr)
FR (1) FR2660193B1 (fr)
GR (1) GR3015693T3 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2034891B1 (es) * 1991-08-08 1993-12-16 Cusi Lab Procedimiento de elaboracion en continuo de sistemas coloidales dispersos, en forma de nanocapsulas o nanoparticulas.
FR2692167B1 (fr) * 1992-06-16 1994-09-16 Centre Nat Rech Scient Préparation et application de nouveaux systèmes colloïdaux nanovésiculaires dispersibles à base de cyclodextrine, sous forme de nanocapsules.
US5576016A (en) * 1993-05-18 1996-11-19 Pharmos Corporation Solid fat nanoemulsions as drug delivery vehicles
US5961970A (en) * 1993-10-29 1999-10-05 Pharmos Corporation Submicron emulsions as vaccine adjuvants
US5877224A (en) 1995-07-28 1999-03-02 Rutgers, The State University Of New Jersey Polymeric drug formulations
FR2766368B1 (fr) * 1997-07-24 2000-03-31 Univ Claude Bernard Lyon Procede de preparation de nanocapsules de type vesiculaire, utilisables notamment comme vecteurs colloidaux de principes actifs pharmaceutiques ou autres
DE19756314C2 (de) * 1997-12-12 2000-06-29 Roland Bodmeier Zubereitung mit verlängerter Verweildauer am Applikationsort
JP2001527040A (ja) * 1997-12-30 2001-12-25 バイオアブソーバブル コンセプツ，インコーポレイティド 神経系の脳血管性疾患を治療、抑制及び防止するためのテトラサイクリン及び／又はテトラサイクリン誘導体
DK1075265T3 (da) * 1998-05-08 2006-06-26 Univ Miami Anvendelse af tetracycliner til behandling af sygdom i de Meibomske kirtler
US6432934B1 (en) * 1998-08-06 2002-08-13 Advanced Vision Research Methods and compositions for topical treatment of eye surface inflammation and related dry eye disease
CA2404737C (fr) * 2000-04-03 2010-06-29 Santen Pharmaceutical Co., Ltd. Substance pour l'administration d'un medicament, contenant du polyalkylene glycol et un phospholipide joints par covalence au medicament
AU2001280165A1 (en) * 2000-08-24 2002-03-04 Santen Pharmaceutical Co. Ltd. Drug-release controlling system
US20060194773A1 (en) * 2001-07-13 2006-08-31 Paratek Pharmaceuticals, Inc. Tetracyline compounds having target therapeutic activities
EP2329826A1 (fr) 2001-07-13 2011-06-08 Paratek Pharmaceuticals, Inc. Tetracyclines pour le traitement de la sclérose en plaques
WO2003028765A1 (fr) * 2001-09-28 2003-04-10 Santen Pharmaceutical Co., Ltd. Injections pour tissu oculaire contenant un medicament lie a du polyethylene glycol
US20060057216A1 (en) * 2004-09-15 2006-03-16 Salamone Joseph C Low-obscuration image transmitting particulate ocular therapeutic formulations
JP2006257080A (ja) * 2005-02-18 2006-09-28 Santen Pharmaceut Co Ltd ステロイド化合物の副作用軽減または回避方法
CN109646422A (zh) * 2019-01-18 2019-04-19 广东药科大学 一种聚丙烯酸树脂包裹载药蒙脱石的眼部给药系统的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4795436A (en) * 1983-11-14 1989-01-03 Bio-Mimetics, Inc. Bioadhesive composition and method of treatment therewith
FR2608942B1 (fr) * 1986-12-31 1991-01-11 Centre Nat Rech Scient Procede de preparation de systemes colloidaux dispersibles d'une substance, sous forme de nanocapsules
DE3722837A1 (de) * 1987-07-10 1989-01-19 Ruetgerswerke Ag Ophthalmisches depotpraeparat
US4997652A (en) * 1987-12-22 1991-03-05 Visionex Biodegradable ocular implants
US4853224A (en) * 1987-12-22 1989-08-01 Visionex Biodegradable ocular implants

Also Published As

Publication number Publication date
ES2071275T3 (es) 1995-06-16
JPH04221322A (ja) 1992-08-11
FR2660193A1 (fr) 1991-10-04
DE69106560D1 (de) 1995-02-23
US5308624A (en) 1994-05-03
ATE116846T1 (de) 1995-01-15
EP0451082A1 (fr) 1991-10-09
JPH0723325B2 (ja) 1995-03-15
EP0451082B1 (fr) 1995-01-11
GR3015693T3 (en) 1995-07-31
DE69106560T2 (de) 1995-05-11
DK0451082T3 (da) 1995-06-19

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Legal Events

Date Code Title Description
TP Transmission of property
ST Notification of lapse

Effective date: 20091231