CA2331257C - Use of tetracyclines for treating meibomian gland disease - Google Patents
Use of tetracyclines for treating meibomian gland disease Download PDFInfo
- Publication number
- CA2331257C CA2331257C CA2331257A CA2331257A CA2331257C CA 2331257 C CA2331257 C CA 2331257C CA 2331257 A CA2331257 A CA 2331257A CA 2331257 A CA2331257 A CA 2331257A CA 2331257 C CA2331257 C CA 2331257C
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- Prior art keywords
- tetracycline
- antimicrobial
- dedimethylamino
- dedimethylaminotetracycline
- patient
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Hematology (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
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| US8487398P | 1998-05-08 | 1998-05-08 | |
| US60/084,873 | 1998-05-08 | ||
| PCT/US1999/009965 WO1999058131A1 (en) | 1998-05-08 | 1999-05-07 | Use of tetracyclines for treating meibomian gland disease |
Publications (2)
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| CA2331257A1 CA2331257A1 (en) | 1999-11-18 |
| CA2331257C true CA2331257C (en) | 2012-01-03 |
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| CA2331257A Expired - Fee Related CA2331257C (en) | 1998-05-08 | 1999-05-07 | Use of tetracyclines for treating meibomian gland disease |
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| EP (2) | EP1075265B1 (enExample) |
| JP (1) | JP4860038B2 (enExample) |
| AT (2) | ATE418989T1 (enExample) |
| AU (1) | AU763164B2 (enExample) |
| CA (1) | CA2331257C (enExample) |
| DE (2) | DE69940227D1 (enExample) |
| DK (2) | DK1676579T3 (enExample) |
| ES (2) | ES2320579T3 (enExample) |
| PT (2) | PT1676579E (enExample) |
| TW (2) | TWI255714B (enExample) |
| WO (1) | WO1999058131A1 (enExample) |
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| AU763164B2 (en) * | 1998-05-08 | 2003-07-17 | University Of Miami | Use of tetracyclines for treating meibomian gland disease |
| US6432934B1 (en) * | 1998-08-06 | 2002-08-13 | Advanced Vision Research | Methods and compositions for topical treatment of eye surface inflammation and related dry eye disease |
| US6506740B1 (en) * | 1998-11-18 | 2003-01-14 | Robert A. Ashley | 4-dedimethylaminotetracycline derivatives |
| EP1171163A1 (en) * | 1999-04-27 | 2002-01-16 | Antibody Systems, Inc. | Compositions containing tetracyclines for treating hemorrhagic virus infections and other disorders |
| US7211267B2 (en) * | 2001-04-05 | 2007-05-01 | Collagenex Pharmaceuticals, Inc. | Methods of treating acne |
| US20040115261A1 (en) * | 2001-04-05 | 2004-06-17 | Ashley Robert A. | Controlled delivery of tetracycline compounds and tetracycline derivatives |
| EP2332547A1 (en) * | 2001-07-13 | 2011-06-15 | Paratek Pharmaceuticals, Inc. | Tetracyclines for the treatment of inflammatory bowel disease |
| US20030073068A1 (en) * | 2001-10-15 | 2003-04-17 | Campbell Robert Edward | Methods for application of tear-based biomarkers to ophthalmic product evaluation and clinical study management |
| US8192749B2 (en) * | 2003-04-16 | 2012-06-05 | Galderma Laboratories Inc. | Methods of simultaneously treating ocular rosacea and acne rosacea |
| WO2003088906A2 (en) * | 2002-04-16 | 2003-10-30 | Collagenex Pharmaceuticals, Inc. | Methods of simultaneously treating ocular rosacea and acne rosacea |
| EP1501490A2 (en) * | 2002-05-06 | 2005-02-02 | Collagenex Pharmaceuticals, Inc. | Methods of simultaneously treating mucositis and fungal infection |
| EP1591110B1 (en) * | 2003-01-22 | 2015-03-18 | Senju Pharmaceutical Co., Ltd. | Percutaneous absorption preparation for treating ophthalmic disease, use thereof and method for migration of ophthalmic remedy into topical tissue in eye |
| WO2004091483A2 (en) * | 2003-04-07 | 2004-10-28 | Shire Laboratories, Inc. | Once daily formulations of tetracyclines |
| US6984628B2 (en) * | 2003-07-15 | 2006-01-10 | Allergan, Inc. | Ophthalmic compositions comprising trefoil factor family peptides |
| WO2005011707A1 (en) * | 2003-07-25 | 2005-02-10 | Warner Chilcott Company, Inc. | A doxycycline metal complex in a solid dosage form |
| WO2007024972A2 (en) * | 2005-08-22 | 2007-03-01 | Quick-Med Technologies, Inc. | Non-leaching absorbent wound dressing |
| CN100340241C (zh) * | 2004-06-28 | 2007-10-03 | 中山大学中山眼科中心 | 一种滴眼液及其制备方法与用途 |
| WO2006078925A2 (en) * | 2005-01-21 | 2006-07-27 | Warner Chilcott Company, Inc. | A tetracycline metal complex in a solid dosage form |
| US7541347B2 (en) | 2007-04-02 | 2009-06-02 | Medicis Pharmaceutical Coropration | Minocycline oral dosage forms for the treatment of acne |
| US8252776B2 (en) | 2007-04-02 | 2012-08-28 | Medicis Pharmaceutical Corporation | Minocycline oral dosage forms for the treatment of acne |
| US7544373B2 (en) | 2007-04-02 | 2009-06-09 | Medicis Pharmaceutical Corporation | Minocycline oral dosage forms for the treatment of acne |
| US8722650B1 (en) | 2005-06-24 | 2014-05-13 | Medicis Pharmaceutical Corporation | Extended-release minocycline dosage forms |
| US20080242642A1 (en) * | 2007-04-02 | 2008-10-02 | Medicis Pharmaceutical Corporation | Minocycline oral dosage forms for the treatment of acne |
| US7919483B2 (en) * | 2005-06-24 | 2011-04-05 | Medicis Pharmaceutical Corporation | Method for the treatment of acne |
| US20080241235A1 (en) * | 2007-04-02 | 2008-10-02 | Medicis Pharmaceutical Corporation | Minocycline oral dosage forms for the treatment of acne |
| US20090043365A1 (en) * | 2005-07-18 | 2009-02-12 | Kolis Scientific, Inc. | Methods, apparatuses, and systems for reducing intraocular pressure as a means of preventing or treating open-angle glaucoma |
| WO2008024100A2 (en) | 2006-08-21 | 2008-02-28 | Tearscience, Inc. | Method and apparatus for treating gland dysfunction |
| US20070060988A1 (en) * | 2005-07-18 | 2007-03-15 | Grenon Stephen M | Melting meibomian gland obstructions |
| US7981145B2 (en) | 2005-07-18 | 2011-07-19 | Tearscience Inc. | Treatment of meibomian glands |
| US8950405B2 (en) * | 2006-05-15 | 2015-02-10 | Tearscience, Inc. | Treatment of obstructive disorders of the eye or eyelid |
| US7981146B2 (en) | 2006-05-15 | 2011-07-19 | Tearscience Inc. | Inner eyelid treatment for treating meibomian gland dysfunction |
| US7981095B2 (en) | 2005-07-18 | 2011-07-19 | Tearscience, Inc. | Methods for treating meibomian gland dysfunction employing fluid jet |
| US8915253B2 (en) | 2005-07-18 | 2014-12-23 | Tearscience, Inc. | Method and apparatus for treating gland dysfunction employing heated medium |
| US8255039B2 (en) | 2006-09-29 | 2012-08-28 | Tearscience, Inc. | Meibomian gland illuminating and imaging |
| WO2013003594A2 (en) | 2011-06-28 | 2013-01-03 | Tearscience, Inc. | Methods and systems for treating meibomian gland dysfunction using radio-frequency energy |
| US20080114423A1 (en) * | 2006-05-15 | 2008-05-15 | Grenon Stephen M | Apparatus for inner eyelid treatment of meibomian gland dysfunction |
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1999
- 1999-05-07 AU AU38879/99A patent/AU763164B2/en not_active Ceased
- 1999-05-07 PT PT06004523T patent/PT1676579E/pt unknown
- 1999-05-07 WO PCT/US1999/009965 patent/WO1999058131A1/en not_active Ceased
- 1999-05-07 EP EP99921754A patent/EP1075265B1/en not_active Expired - Lifetime
- 1999-05-07 DK DK06004523T patent/DK1676579T3/da active
- 1999-05-07 EP EP06004523A patent/EP1676579B1/en not_active Expired - Lifetime
- 1999-05-07 JP JP2000547982A patent/JP4860038B2/ja not_active Expired - Fee Related
- 1999-05-07 AT AT06004523T patent/ATE418989T1/de active
- 1999-05-07 DK DK99921754T patent/DK1075265T3/da active
- 1999-05-07 DE DE69940227T patent/DE69940227D1/de not_active Expired - Lifetime
- 1999-05-07 AT AT99921754T patent/ATE319456T1/de active
- 1999-05-07 DE DE69930252T patent/DE69930252T2/de not_active Expired - Lifetime
- 1999-05-07 US US09/307,182 patent/US6455583B1/en not_active Expired - Fee Related
- 1999-05-07 CA CA2331257A patent/CA2331257C/en not_active Expired - Fee Related
- 1999-05-07 ES ES06004523T patent/ES2320579T3/es not_active Expired - Lifetime
- 1999-05-07 PT PT99921754T patent/PT1075265E/pt unknown
- 1999-05-07 ES ES99921754T patent/ES2260912T3/es not_active Expired - Lifetime
- 1999-05-25 TW TW094111310A patent/TWI255714B/zh not_active IP Right Cessation
- 1999-05-25 TW TW088107469A patent/TWI255713B/zh not_active IP Right Cessation
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2002
- 2002-08-22 US US10/225,341 patent/US20030114426A1/en not_active Abandoned
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2005
- 2005-12-07 US US11/297,780 patent/US20060154901A1/en not_active Abandoned
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2007
- 2007-10-11 US US11/974,435 patent/US20080214510A1/en not_active Abandoned
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2010
- 2010-07-21 US US12/841,058 patent/US20110039805A1/en not_active Abandoned
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2011
- 2011-12-01 US US13/309,145 patent/US20120088739A1/en not_active Abandoned
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| DK1075265T3 (da) | 2006-06-26 |
| TW200526232A (en) | 2005-08-16 |
| US20060154901A1 (en) | 2006-07-13 |
| DK1676579T3 (da) | 2009-03-16 |
| US6455583B1 (en) | 2002-09-24 |
| JP4860038B2 (ja) | 2012-01-25 |
| JP2002514602A (ja) | 2002-05-21 |
| US20080214510A1 (en) | 2008-09-04 |
| TWI255713B (en) | 2006-06-01 |
| PT1676579E (pt) | 2009-03-24 |
| US20030114426A1 (en) | 2003-06-19 |
| DE69930252T2 (de) | 2006-12-14 |
| EP1676579A3 (en) | 2006-07-12 |
| DE69930252D1 (de) | 2006-05-04 |
| EP1676579A2 (en) | 2006-07-05 |
| EP1676579B1 (en) | 2008-12-31 |
| ES2320579T3 (es) | 2009-05-25 |
| AU3887999A (en) | 1999-11-29 |
| AU763164B2 (en) | 2003-07-17 |
| US20110039805A1 (en) | 2011-02-17 |
| WO1999058131A1 (en) | 1999-11-18 |
| EP1075265A1 (en) | 2001-02-14 |
| ATE418989T1 (de) | 2009-01-15 |
| HK1034899A1 (en) | 2001-11-09 |
| ES2260912T3 (es) | 2006-11-01 |
| CA2331257A1 (en) | 1999-11-18 |
| ATE319456T1 (de) | 2006-03-15 |
| DE69940227D1 (de) | 2009-02-12 |
| EP1075265B1 (en) | 2006-03-08 |
| HK1089696A1 (en) | 2006-12-08 |
| TWI255714B (en) | 2006-06-01 |
| PT1075265E (pt) | 2006-07-31 |
| US20120088739A1 (en) | 2012-04-12 |
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