DE69803112D1 - Arzneistoffabgabesystem für zwei oder mehr Aktivsubstanzen - Google Patents

Arzneistoffabgabesystem für zwei oder mehr Aktivsubstanzen

Info

Publication number
DE69803112D1
DE69803112D1 DE69803112T DE69803112T DE69803112D1 DE 69803112 D1 DE69803112 D1 DE 69803112D1 DE 69803112 T DE69803112 T DE 69803112T DE 69803112 T DE69803112 T DE 69803112T DE 69803112 D1 DE69803112 D1 DE 69803112D1
Authority
DE
Germany
Prior art keywords
delivery system
drug delivery
active substances
substances
active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69803112T
Other languages
English (en)
Other versions
DE69803112T2 (de
Inventor
R J J Groenewegen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Organon NV
Original Assignee
Akzo Nobel NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8228203&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69803112(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Akzo Nobel NV filed Critical Akzo Nobel NV
Publication of DE69803112D1 publication Critical patent/DE69803112D1/de
Application granted granted Critical
Publication of DE69803112T2 publication Critical patent/DE69803112T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/2853Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
DE69803112T 1997-04-11 1998-04-09 Arzneistoffabgabesystem für zwei oder mehr Aktivsubstanzen Expired - Lifetime DE69803112T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97201098 1997-04-11

Publications (2)

Publication Number Publication Date
DE69803112D1 true DE69803112D1 (de) 2002-02-14
DE69803112T2 DE69803112T2 (de) 2002-07-18

Family

ID=8228203

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69803112T Expired - Lifetime DE69803112T2 (de) 1997-04-11 1998-04-09 Arzneistoffabgabesystem für zwei oder mehr Aktivsubstanzen

Country Status (27)

Country Link
US (1) US5989581A (de)
EP (1) EP0876815B1 (de)
JP (2) JP4982670B2 (de)
KR (1) KR100492676B1 (de)
CN (1) CN1163222C (de)
AR (1) AR011709A1 (de)
AT (1) ATE211646T1 (de)
AU (1) AU726934B2 (de)
BR (1) BR9801027B1 (de)
CA (1) CA2233753C (de)
CZ (1) CZ294099B6 (de)
DE (1) DE69803112T2 (de)
DK (1) DK0876815T3 (de)
ES (1) ES2171283T3 (de)
HK (1) HK1016886A1 (de)
HU (1) HU222343B1 (de)
ID (1) ID21259A (de)
IL (2) IL123813A0 (de)
NO (1) NO320394B1 (de)
NZ (1) NZ330145A (de)
PL (1) PL192449B1 (de)
PT (1) PT876815E (de)
RU (1) RU2206325C2 (de)
SG (1) SG65061A1 (de)
TR (1) TR199800648A1 (de)
TW (1) TW358031B (de)
ZA (1) ZA982911B (de)

Families Citing this family (86)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL123813A0 (en) * 1997-04-11 1998-10-30 Akzo Nobel Nv Drug delivery system for two or more active substances
US6039968A (en) 1997-06-24 2000-03-21 Hoechst Marion Roussel Intravaginal drug delivery device
US6361780B1 (en) * 1998-11-12 2002-03-26 Cardiac Pacemakers, Inc. Microporous drug delivery system
US6217895B1 (en) 1999-03-22 2001-04-17 Control Delivery Systems Method for treating and/or preventing retinal diseases with sustained release corticosteroids
US6371970B1 (en) 1999-07-30 2002-04-16 Incept Llc Vascular filter having articulation region and methods of use in the ascending aorta
US7369463B1 (en) 2000-02-21 2008-05-06 N.V. Organon Electronic alarm timer for use with a medical regimen
US20040115268A1 (en) * 2000-04-26 2004-06-17 Control Delivery Systems, Inc. Systemic delivery of antiviral agents
US6375972B1 (en) 2000-04-26 2002-04-23 Control Delivery Systems, Inc. Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof
US7187980B2 (en) * 2001-11-09 2007-03-06 Oscor Inc. Cardiac lead with steroid eluting ring
TWI297685B (en) 2002-04-04 2008-06-11 Organon Nv Non-steroidal progesterone receptor modulators
US8871241B2 (en) * 2002-05-07 2014-10-28 Psivida Us, Inc. Injectable sustained release delivery devices
WO2003094888A1 (en) * 2002-05-07 2003-11-20 Control Delivery Systems, Inc. Processes for forming a drug delivery device
US7795280B2 (en) 2002-11-07 2010-09-14 N.V. Organon Indoles useful in the treatment of androgen-receptor related diseases
US7357046B2 (en) * 2002-12-16 2008-04-15 N. V. Organon Method for dissolution testing of a pharmaceutical delivery device
WO2004055209A1 (en) * 2002-12-16 2004-07-01 Akzo Nobel N.V. Vessel, method and apparatus for dissolution testing of an annular pharmaceutical delivery device
ATE461681T1 (de) 2003-04-29 2010-04-15 Gen Hospital Corp Verfahren und vorrichtungen für die verzögerte freisetzung von mehreren arzneimitteln
TWI336627B (en) * 2003-05-23 2011-02-01 Organon Nv Drug delivery system,and use and manufacturing method thereof
MXPA06007851A (es) * 2004-01-15 2007-01-31 Warner Chilcott Co Inc Profarmacos di-esteroidales de etinil estradiol.
CN1906206A (zh) * 2004-01-15 2007-01-31 沃纳奇尔科特公司 雌二醇的二-甾族前体药物
ATE434433T1 (de) 2004-03-24 2009-07-15 Organon Nv Arzneimittelabgabesystem auf basis von polyethylen-vinylacetat-copolymeren
TW200531977A (en) 2004-03-25 2005-10-01 Akzo Nobel Nv Progesterone receptor modulators
TW200602317A (en) 2004-04-23 2006-01-16 Akzo Nobel Nv Novel androgens
CN101137347A (zh) * 2004-11-16 2008-03-05 列日大学 包含水凝胶基质和微载体的活性物质递送系统
CN100366242C (zh) * 2005-01-13 2008-02-06 杭州容立医药科技有限公司 防滑脱阴道药物释放体系及其制造工艺和在制药中的应用
US20100241219A1 (en) * 2005-06-20 2010-09-23 Abbeymoor Medical , Inc Medicament delivery article, accessory & system
TW200727920A (en) * 2005-06-21 2007-08-01 Organon Nv New regimens for oral monophasic contraceptives
WO2007024338A2 (en) * 2005-07-12 2007-03-01 Warner Chilcott Company, Inc. 3 -ester prodrugs of ethynylestradiol
US20070015741A1 (en) * 2005-07-12 2007-01-18 James Keown Novel prodrugs of estradiol
CN1899643B (zh) * 2005-07-20 2010-12-29 上海市计划生育科学研究所 含有抗雌激素和抗孕激素复合制剂的阴道环或宫内释药装置及其制药用途
CA2618349C (en) * 2005-08-11 2016-05-31 Massachusetts Institute Of Technology Intravesical drug delivery device and method
US20070077269A1 (en) * 2005-10-04 2007-04-05 Woodward John R Method of birth control and hormone regulation
US7989442B2 (en) 2006-09-27 2011-08-02 N.V. Organon Progesterone receptor modulators
JP2010510290A (ja) * 2006-11-22 2010-04-02 ナームローゼ・フエンノートチヤツプ・オルガノン ミルタザピンのための膣送達系
TW200840595A (en) * 2006-12-12 2008-10-16 Organon Nv Oral contraceptive spray
US8063037B2 (en) 2007-05-07 2011-11-22 N. V. Organon Progesterone receptor modulators
US8741329B2 (en) * 2007-09-21 2014-06-03 Merck Sharp & Dohme B.V. Drug delivery system
CN101896221B (zh) * 2007-12-11 2013-06-05 麻省理工学院 用于治疗膀胱和其它体囊或体腔的可植入式药物递送设备和方法
CN102176931B (zh) * 2008-08-09 2015-03-04 麻省理工学院 治疗男性泌尿生殖组织和外周组织的可植入药物递送设备和方法
US20100040671A1 (en) * 2008-08-12 2010-02-18 Ahmed Salah U Intravaginal Devices With a Rigid Support, Methods of Making, and Uses Thereof
WO2010054296A2 (en) * 2008-11-07 2010-05-14 Combinent Biomedical Systems, Inc. Devices and methods for treating and/or preventing diseases
FI121000B (fi) * 2008-11-19 2010-06-15 Bayer Schering Pharma Oy Intravaginaalinen antojärjestelmä ja menetelmä sen valmistamiseksi
UY32492A (es) 2009-03-17 2010-10-29 Organon Nv Dispositivo de suministro de droga zootécnica.
WO2010118178A2 (en) 2009-04-07 2010-10-14 Garfield Robert E Uterine electrical stimulation system and method
US8568374B2 (en) * 2009-05-04 2013-10-29 Merck Sharp & Dohme B.V. Intrauterine system
EP4108216A1 (de) 2009-06-03 2022-12-28 Forsight Vision5, Inc. Wirkstofffreisetzung im vorderen augensegment
CN102470237A (zh) 2009-06-26 2012-05-23 塔里斯生物医药公司 用于可植入药物递送装置的固体药物片剂
EP2456421B1 (de) 2009-07-21 2017-04-05 The Population Council, Inc. Mehrschichtiger vaginalring mit gradient
US9017312B2 (en) 2009-09-10 2015-04-28 Taris Biomedical Llc Implantable device for controlled drug delivery
US20110236462A1 (en) * 2010-03-28 2011-09-29 Shaked Ze Ev Intravaginal drug delivery device
US20130096092A1 (en) 2010-06-10 2013-04-18 Health And Human Services Thioether prodrug compositions as anti-hiv and anti-retroviral agents
US8580294B2 (en) 2010-10-19 2013-11-12 International Partnership For Microbicides Platinum-catalyzed intravaginal rings
CA3063888C (en) 2010-10-27 2020-12-22 Dignity Health Uterine electrical stimulation system and method
US9872983B2 (en) 2010-10-27 2018-01-23 Dignity Health Uterine electrical stimulation system and method
JP2014503554A (ja) 2011-01-10 2014-02-13 タリス バイオメディカル,インコーポレイテッド 膀胱痛及び刺激性排尿の持続的治療の使用のためのリドカインレジメン
KR101263916B1 (ko) 2011-01-11 2013-05-13 이장희 성 호르몬 방출 장치 및 이를 이용한 동물 피임 및 발정 유도 방법
WO2012106714A1 (en) * 2011-02-04 2012-08-09 Taris Biomedical, Inc. Implantable device for controlled release of low solubility drug
EP2734262B1 (de) * 2011-07-20 2018-02-28 Patrick F. Kiser Intravaginalen ringen zur wirkstofffreisetzung
EP2749286B1 (de) 2011-08-26 2017-03-01 Universidad De Santiago De Chile Verwendung der nichtsteroidalen entzündungshemmer meloxicam und piroxicam in intravaginalringen zur unterbrechung des eisprungs bei frauen
KR20150051234A (ko) 2012-09-03 2015-05-11 에쏘세아 파르밍 에쎄.아. 수생 생물종의 배향 및/또는 억제를 위한 저장조 케이지 침지 시스템
AU2013349776A1 (en) 2012-11-22 2015-05-28 Bayer Pharma Aktiengesellschaft Use and application regimen of a pharmaceutical composition containing levonorgestrel and a COX inhibitor for on-demand contraception
DK2964088T3 (da) 2013-03-08 2023-06-06 Li Galli B V I O Vaginalt lægemiddeladministrations- og/eller diagnosesystem
AU2014232801B2 (en) 2013-03-15 2019-01-17 Taris Biomedical Llc Drug delivery devices with drug-permeable component and methods
RS60847B1 (sr) 2013-08-19 2020-10-30 Taris Biomedical Llc Uređaji za davanje više jedinica leka
WO2015035003A1 (en) 2013-09-05 2015-03-12 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Thioether prodrug compositions as anti-hiv and anti-retroviral agents
WO2015055789A1 (en) 2013-10-17 2015-04-23 Bayer Pharma Aktiengesellschaft INTRAVAGINAL USE OF 18-METHYL-15ß,16ß-METHYLENE-19-NOR-20-SPIROX-4-EN-3-ONES, INTRAVAGINAL RINGS COMPRISING 18-METHYL-15ß,16ß-METHYLENE-19-NOR-20-SPIROX-4-EN-3-ONES, AND USE THEREOF IN CONTRACEPTION
US10137031B2 (en) 2013-11-14 2018-11-27 International Partnership For Microbicides, Inc. Combination therapy intravaginal rings
US10413504B2 (en) 2013-12-11 2019-09-17 Merck Sharp & Dohme Corp. Intravaginal ring drug delivery system
EP3079659B1 (de) 2013-12-11 2020-10-28 Merck Sharp & Dohme B.V. Arzneimittelliefersystem zur verabreichung von virenbekämpfungsmitteln
BR112017016424B1 (pt) 2015-03-31 2022-10-25 Merck Sharp & Dohme B.V. Aplicador de anel vaginal, e, kit
US20160296532A1 (en) 2015-04-13 2016-10-13 Forsight Vision5, Inc. Ocular Insert Composition of a Semi-Crystalline or Crystalline Pharmaceutically Active Agent
EP3285850A1 (de) 2015-04-23 2018-02-28 TARIS Biomedical LLC Wirkstoffabgabevorrichtungen mit einer wirkstoffdurchlässigen komponente und verfahren
EP3294300A1 (de) 2015-05-13 2018-03-21 Bayer Oy Vorrichtung zur freisetzung eines langwirkenden arzneimittels und dessen verwendung zur verhütung
EP3272333A1 (de) 2016-07-22 2018-01-24 Chemo Research, S.L. Vaginale zubereitung enthaltend eine kombination von östrogen und vitamin d
EP3395335A1 (de) 2017-04-24 2018-10-31 Kern Pharma, S.L. Vaginalring zur gleichzeitigen freisetzung zweier wirkstoffe
DE102017113166A1 (de) * 2017-06-14 2018-12-20 Amw Gmbh Depotform zur Abgabe eines Östrogen-Wirkstoffs
US11103460B2 (en) 2017-08-07 2021-08-31 Board Of Regents, The University Of Texas System Fabrication methods for nanodelivery systems for long term controlled delivery of active pharmaceutical ingredients
CN111971026A (zh) 2018-05-24 2020-11-20 塞拉尼斯伊娃高性能聚合物公司 用于持续释放大分子药物化合物的可植入器件
EP3801378A4 (de) 2018-05-24 2022-02-23 Celanese EVA Performance Polymers LLC Implantierbare vorrichtung zur verzögerten freisetzung einer makromolekularen wirkstoffverbindung
CN113365634A (zh) * 2018-12-11 2021-09-07 卢品公司 超低剂量雌激素组合的药物递送系统及其方法和用途
US10632066B1 (en) 2019-02-01 2020-04-28 The Population Council, Inc. Method of providing birth control
US11529308B2 (en) 2019-06-21 2022-12-20 The Population Council, Inc. System for providing birth control
US10918649B2 (en) 2019-06-21 2021-02-16 The Population Council, Inc. System for providing birth control
CN113164383B (zh) 2019-10-12 2022-08-12 国家卫生健康委科学技术研究所 用于黄体支持的阴道缓释给药系统及其制备方法与应用
AU2020391230A1 (en) 2019-11-27 2022-06-09 Oak Crest Institute Of Science Sustained release drug delivery device
USD935018S1 (en) 2020-04-07 2021-11-02 The Population Council, Inc. Contraceptive
WO2023133517A1 (en) 2022-01-06 2023-07-13 Oak Crest Institute Of Science Subdermal implant for sustained drug delivery

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3040978A1 (de) * 1980-10-28 1982-05-27 Schering Ag, 1000 Berlin Und 4619 Bergkamen Vaginalring
ZA857643B (en) * 1984-10-12 1986-05-28 Akzo Nv Release system for two or more active substances
US4816258A (en) * 1987-02-26 1989-03-28 Alza Corporation Transdermal contraceptive formulations
DE19975054I2 (de) * 1987-08-08 2000-04-13 Akzo Nobel Nv Kontrazeptives Implantat
JPH03123727A (ja) * 1989-10-04 1991-05-27 Nitto Denko Corp 経皮吸収製剤
ES2166894T3 (es) * 1995-07-04 2002-05-01 Akzo Nobel Nv Dispositivos anulares.
US5906830A (en) * 1995-09-08 1999-05-25 Cygnus, Inc. Supersaturated transdermal drug delivery systems, and methods for manufacturing the same
IL123813A0 (en) * 1997-04-11 1998-10-30 Akzo Nobel Nv Drug delivery system for two or more active substances

Also Published As

Publication number Publication date
HUP9800863A3 (en) 2000-06-28
BR9801027A (pt) 2000-01-11
JPH10287549A (ja) 1998-10-27
HK1016886A1 (en) 1999-11-12
CA2233753A1 (en) 1998-10-11
AR011709A1 (es) 2000-08-30
AU6075198A (en) 1998-10-15
BR9801027B1 (pt) 2009-01-13
RU2206325C2 (ru) 2003-06-20
EP0876815B1 (de) 2002-01-09
IL123813A0 (en) 1998-10-30
NO320394B1 (no) 2005-11-28
KR100492676B1 (ko) 2005-10-19
CZ294099B6 (cs) 2004-10-13
EP0876815A1 (de) 1998-11-11
NZ330145A (en) 1999-05-28
CZ110298A3 (cs) 1998-10-14
KR19980081290A (ko) 1998-11-25
JP2009256378A (ja) 2009-11-05
CN1196930A (zh) 1998-10-28
SG65061A1 (en) 1999-05-25
DK0876815T3 (da) 2002-04-22
TR199800648A1 (xx) 1998-10-21
ATE211646T1 (de) 2002-01-15
PT876815E (pt) 2002-07-31
DE69803112T2 (de) 2002-07-18
ID21259A (id) 1999-05-12
JP4982670B2 (ja) 2012-07-25
CN1163222C (zh) 2004-08-25
PL325774A1 (en) 1998-10-12
IL123813A (en) 2001-11-25
HU9800863D0 (en) 1998-05-28
HU222343B1 (hu) 2003-06-28
HUP9800863A2 (hu) 1999-02-01
AU726934B2 (en) 2000-11-23
PL192449B1 (pl) 2006-10-31
NO981638D0 (no) 1998-04-08
CA2233753C (en) 2001-12-25
NO981638L (no) 1998-10-12
ZA982911B (en) 1998-10-09
ES2171283T3 (es) 2002-09-01
US5989581A (en) 1999-11-23
TW358031B (en) 1999-05-11

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