HUP9800863A2 - Gyógyszerszállító rendszer két vagy több hatóanyaghoz - Google Patents

Gyógyszerszállító rendszer két vagy több hatóanyaghoz

Info

Publication number
HUP9800863A2
HUP9800863A2 HU9800863A HUP9800863A HUP9800863A2 HU P9800863 A2 HUP9800863 A2 HU P9800863A2 HU 9800863 A HU9800863 A HU 9800863A HU P9800863 A HUP9800863 A HU P9800863A HU P9800863 A2 HUP9800863 A2 HU P9800863A2
Authority
HU
Hungary
Prior art keywords
compound
core
delivery system
stimulatory
steroid
Prior art date
Application number
HU9800863A
Other languages
English (en)
Inventor
R.J.J. Groenewegen
Original Assignee
Akzo Nobel N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8228203&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP9800863(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Akzo Nobel N.V. filed Critical Akzo Nobel N.V.
Publication of HU9800863D0 publication Critical patent/HU9800863D0/hu
Publication of HUP9800863A2 publication Critical patent/HUP9800863A2/hu
Publication of HUP9800863A3 publication Critical patent/HUP9800863A3/hu
Publication of HU222343B1 publication Critical patent/HU222343B1/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/2853Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Reproductive Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A találmány tárgya hatóanyag-szállító rendszer, amely legalább egyrekeszt tartalmaz, amely egy hőre lágyűló magból és ezt körülvevő,hőre lágyűló bevőnatból áll, amely mag szteőrid prőgesztőgén vegyületés szteőrid ösztrőgén vegyület keverékét tartalmazza őlyan arányban,amely lehetővé teszi a pőlimerből mind a prőgesztőgén, mind azösztrőgén vegyület fiziőlógiailag szükséges mennyiségben valóközvetlen felszabadűlását és amely prőgesztőgén vegyületet kezdetben apőlimer magban relatíve alacsőny mértékű túltelítettséggel van őldva,és az ösztrőgén vegyületet a pőlimer magban a prőgesztőgén vegyületnélalacsőnyabb kőncentrációban van őldva, és az említett hőre lágyűlóbevőnat mind a prőgesztőgén, mind az ösztrőgén vegyület számárapermeábilis. A találmány szerinti hatóanyag-szállító rendszer különösen alkalmashüvelyi alkalmazásra főgamzásgátlás céljára. ŕ
HU9800863A 1997-04-11 1998-04-10 Gyógyszer-szállító rendszer két vagy több hatóanyaghoz HU222343B1 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97201098 1997-04-11

Publications (4)

Publication Number Publication Date
HU9800863D0 HU9800863D0 (en) 1998-05-28
HUP9800863A2 true HUP9800863A2 (hu) 1999-02-01
HUP9800863A3 HUP9800863A3 (en) 2000-06-28
HU222343B1 HU222343B1 (hu) 2003-06-28

Family

ID=8228203

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9800863A HU222343B1 (hu) 1997-04-11 1998-04-10 Gyógyszer-szállító rendszer két vagy több hatóanyaghoz

Country Status (27)

Country Link
US (1) US5989581A (hu)
EP (1) EP0876815B1 (hu)
JP (2) JP4982670B2 (hu)
KR (1) KR100492676B1 (hu)
CN (1) CN1163222C (hu)
AR (1) AR011709A1 (hu)
AT (1) ATE211646T1 (hu)
AU (1) AU726934B2 (hu)
BR (1) BR9801027B1 (hu)
CA (1) CA2233753C (hu)
CZ (1) CZ294099B6 (hu)
DE (1) DE69803112T2 (hu)
DK (1) DK0876815T3 (hu)
ES (1) ES2171283T3 (hu)
HK (1) HK1016886A1 (hu)
HU (1) HU222343B1 (hu)
ID (1) ID21259A (hu)
IL (2) IL123813A0 (hu)
NO (1) NO320394B1 (hu)
NZ (1) NZ330145A (hu)
PL (1) PL192449B1 (hu)
PT (1) PT876815E (hu)
RU (1) RU2206325C2 (hu)
SG (1) SG65061A1 (hu)
TR (1) TR199800648A1 (hu)
TW (1) TW358031B (hu)
ZA (1) ZA982911B (hu)

Families Citing this family (88)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL123813A0 (en) * 1997-04-11 1998-10-30 Akzo Nobel Nv Drug delivery system for two or more active substances
US6039968A (en) 1997-06-24 2000-03-21 Hoechst Marion Roussel Intravaginal drug delivery device
US6361780B1 (en) * 1998-11-12 2002-03-26 Cardiac Pacemakers, Inc. Microporous drug delivery system
US6217895B1 (en) * 1999-03-22 2001-04-17 Control Delivery Systems Method for treating and/or preventing retinal diseases with sustained release corticosteroids
US6371970B1 (en) 1999-07-30 2002-04-16 Incept Llc Vascular filter having articulation region and methods of use in the ascending aorta
US7369463B1 (en) 2000-02-21 2008-05-06 N.V. Organon Electronic alarm timer for use with a medical regimen
US6375972B1 (en) 2000-04-26 2002-04-23 Control Delivery Systems, Inc. Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof
US20040115268A1 (en) * 2000-04-26 2004-06-17 Control Delivery Systems, Inc. Systemic delivery of antiviral agents
US6671562B2 (en) 2001-11-09 2003-12-30 Oscor Inc. High impedance drug eluting cardiac lead
TWI297685B (en) 2002-04-04 2008-06-11 Organon Nv Non-steroidal progesterone receptor modulators
CA2484632C (en) * 2002-05-07 2012-12-11 Control Delivery Systems, Inc. Processes for forming a drug delivery device
US8871241B2 (en) * 2002-05-07 2014-10-28 Psivida Us, Inc. Injectable sustained release delivery devices
KR20050072812A (ko) 2002-11-07 2005-07-12 악조 노벨 엔.브이. 안드로겐-수용체와 관련된 질병의 치료에 효과적인 인돌
US7357046B2 (en) * 2002-12-16 2008-04-15 N. V. Organon Method for dissolution testing of a pharmaceutical delivery device
DE60316344T2 (de) * 2002-12-16 2008-06-12 N.V. Organon Behälter ,vorrichtung und verfahren zur prüfung des auflösens von pharmazeutischen zusammensetzungen
EP1620060B1 (en) 2003-04-29 2010-03-24 The General Hospital Corporation Methods and devices for the sustained release of multiple drugs
TWI336627B (en) 2003-05-23 2011-02-01 Organon Nv Drug delivery system,and use and manufacturing method thereof
WO2005070949A1 (en) * 2004-01-15 2005-08-04 Warner Chilcott Company, Inc. Di-steroidal prodrugs of estradiol
US7067504B2 (en) * 2004-01-15 2006-06-27 Warner Chilcott Company, Inc. Di-steroidal prodrugs of ethinyl estradiol
WO2005089723A1 (en) 2004-03-24 2005-09-29 N.V. Organon Drug delivery system based on polyethylene vinylacetate copolymers
TW200531977A (en) 2004-03-25 2005-10-01 Akzo Nobel Nv Progesterone receptor modulators
TW200602317A (en) 2004-04-23 2006-01-16 Akzo Nobel Nv Novel androgens
JP2008520783A (ja) * 2004-11-16 2008-06-19 ユニベルシテ・ド・リエージュ ヒドロゲルマトリックスおよびマイクロキャリアを含む活性物質供給システム
CN100366242C (zh) * 2005-01-13 2008-02-06 杭州容立医药科技有限公司 防滑脱阴道药物释放体系及其制造工艺和在制药中的应用
EP1904147A4 (en) * 2005-06-20 2009-05-27 Abbeymoor Medical Inc MEDICATION DISPOSABLE ARTICLES, ACCESSORIES AND SYSTEM
TW200727920A (en) * 2005-06-21 2007-08-01 Organon Nv New regimens for oral monophasic contraceptives
CN101218245B (zh) 2005-07-12 2011-08-17 沃纳奇尔科特有限责任公司 炔雌醇的3-酯前药
EP1910402A2 (en) * 2005-07-12 2008-04-16 Warner Chilcott Company, Inc. 3-ester prodrugs of estradiol
CN1899643B (zh) * 2005-07-20 2010-12-29 上海市计划生育科学研究所 含有抗雌激素和抗孕激素复合制剂的阴道环或宫内释药装置及其制药用途
ES2400091T3 (es) 2005-08-11 2013-04-05 Massachusetts Institute Of Technology Dispositivo de suministro de fármacos intravesical y método
US20070077269A1 (en) * 2005-10-04 2007-04-05 Woodward John R Method of birth control and hormone regulation
US7989442B2 (en) 2006-09-27 2011-08-02 N.V. Organon Progesterone receptor modulators
AU2007324467A1 (en) * 2006-11-22 2008-05-29 N.V. Organon Vaginal delivery system for mirtazapine
TW200840595A (en) * 2006-12-12 2008-10-16 Organon Nv Oral contraceptive spray
US8063037B2 (en) 2007-05-07 2011-11-22 N. V. Organon Progesterone receptor modulators
TW200930343A (en) * 2007-09-21 2009-07-16 Organon Nv Drug delivery system
BRPI0820800B8 (pt) * 2007-12-11 2021-06-22 Massachusetts Inst Technology dispositivo médico implantável para liberação controlada de droga
BRPI0917135A2 (pt) * 2008-08-09 2015-11-10 Massachusetts Inst Technology dispositivo médico para extensão e retenção em uma vesícula seminal, duto ejaculatório, próstata ou vaso deferente de um paciente, uso de um elastômero reabsorvível, e, dispositivo de bomba osmótica.
US20100040671A1 (en) * 2008-08-12 2010-02-18 Ahmed Salah U Intravaginal Devices With a Rigid Support, Methods of Making, and Uses Thereof
WO2010054296A2 (en) * 2008-11-07 2010-05-14 Combinent Biomedical Systems, Inc. Devices and methods for treating and/or preventing diseases
FI121000B (fi) * 2008-11-19 2010-06-15 Bayer Schering Pharma Oy Intravaginaalinen antojärjestelmä ja menetelmä sen valmistamiseksi
WO2010105995A2 (en) 2009-03-17 2010-09-23 Intervet International B.V. Zoo-technical drug delivery device
CN102481450B (zh) 2009-04-07 2015-09-16 威斯特天主教保健中心 子宫电刺激系统及方法
US8568374B2 (en) * 2009-05-04 2013-10-29 Merck Sharp & Dohme B.V. Intrauterine system
ES2921527T3 (es) 2009-06-03 2022-08-29 Forsight Vision5 Inc Administración de fármaco en segmento anterior
US10543166B2 (en) 2009-06-26 2020-01-28 Taris Biomedical Llc Implantable drug delivery devices and methods of making the same
JP5690826B2 (ja) 2009-07-21 2015-03-25 ザ・ポピュレイション・カウンシル,インコーポレイテッド 多層状勾配膣リング
US9017312B2 (en) 2009-09-10 2015-04-28 Taris Biomedical Llc Implantable device for controlled drug delivery
CA2798034A1 (en) * 2010-03-28 2011-10-13 Evestra, Inc. Intravaginal drug delivery device
EP2580191A2 (en) 2010-06-10 2013-04-17 The U.S.A. as represented by the Secretary, Department of Health and Human Services Thioether prodrug compositions as anti-hiv and anti-retroviral agents
US8580294B2 (en) 2010-10-19 2013-11-12 International Partnership For Microbicides Platinum-catalyzed intravaginal rings
US9872983B2 (en) 2010-10-27 2018-01-23 Dignity Health Uterine electrical stimulation system and method
WO2012058289A2 (en) 2010-10-27 2012-05-03 Dignity Health Uterine electrical stimulation system and method
EP2663300B1 (en) 2011-01-10 2023-03-08 TARIS Biomedical LLC Lidocaine regimen for the use of sustained treatment of bladder pain and irritative voiding
KR101263916B1 (ko) 2011-01-11 2013-05-13 이장희 성 호르몬 방출 장치 및 이를 이용한 동물 피임 및 발정 유도 방법
EP2670398B1 (en) * 2011-02-04 2017-06-07 TARIS Biomedical LLC Implantable device for controlled release of low solubility drug
BR112014001450A2 (pt) * 2011-07-20 2017-07-18 F Kiser Patrick dispositivos intravaginais para distribuição de droga
EP2749286B1 (en) 2011-08-26 2017-03-01 Universidad De Santiago De Chile Use of non-steroidal anti-inflammatory drugs meloxicam and piroxicam, administered intravaginally, for interruption of a woman's ovulation process
KR20150051234A (ko) 2012-09-03 2015-05-11 에쏘세아 파르밍 에쎄.아. 수생 생물종의 배향 및/또는 억제를 위한 저장조 케이지 침지 시스템
KR20150085512A (ko) 2012-11-22 2015-07-23 바이엘 파마 악티엔게젤샤프트 필요시 피임을 위한 레보노르게스트렐 및 cox 억제제 함유 제약 조성물의 용도 및 적용 요법
WO2014135521A1 (en) 2013-03-08 2014-09-12 Li Galli B.V. Vaginal drug delivery and/or diagnostic system
EP2968880A1 (en) 2013-03-15 2016-01-20 TARIS Biomedical LLC Drug delivery devices with drug-permeable component and methods
KR102488491B1 (ko) 2013-08-19 2023-01-12 타리스 바이오메디컬 엘엘씨 다중 유닛 약물 전달 장치 및 방법
WO2015035003A1 (en) 2013-09-05 2015-03-12 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Thioether prodrug compositions as anti-hiv and anti-retroviral agents
WO2015055789A1 (en) 2013-10-17 2015-04-23 Bayer Pharma Aktiengesellschaft INTRAVAGINAL USE OF 18-METHYL-15ß,16ß-METHYLENE-19-NOR-20-SPIROX-4-EN-3-ONES, INTRAVAGINAL RINGS COMPRISING 18-METHYL-15ß,16ß-METHYLENE-19-NOR-20-SPIROX-4-EN-3-ONES, AND USE THEREOF IN CONTRACEPTION
US10137031B2 (en) 2013-11-14 2018-11-27 International Partnership For Microbicides, Inc. Combination therapy intravaginal rings
US10413504B2 (en) * 2013-12-11 2019-09-17 Merck Sharp & Dohme Corp. Intravaginal ring drug delivery system
WO2015086489A1 (en) 2013-12-11 2015-06-18 Merck Sharp & Dohme B.V. Drug delivery system for delivery of anti-virals
EP3277241B1 (en) 2015-03-31 2023-12-20 Merck Sharp & Dohme B.V. Vaginal ring applicator
EP3283004A4 (en) 2015-04-13 2018-12-05 Forsight Vision5, Inc. Ocular insert composition of semi-crystalline or crystalline pharmaceutically active agent
WO2016172704A1 (en) 2015-04-23 2016-10-27 Taris Biomedical Llc Drug delivery devices with drug-permeable component and methods
EP3294300A1 (en) 2015-05-13 2018-03-21 Bayer Oy A long acting drug delivery device and its use in contraception
EP3272333A1 (en) 2016-07-22 2018-01-24 Chemo Research, S.L. Vaginal composition comprising a combination of estrogen and vitamin d
EP3395335A1 (en) 2017-04-24 2018-10-31 Kern Pharma, S.L. Vaginal ring for the simultaneous release of two active ingredients
DE102017113166A1 (de) * 2017-06-14 2018-12-20 Amw Gmbh Depotform zur Abgabe eines Östrogen-Wirkstoffs
US11103460B2 (en) 2017-08-07 2021-08-31 Board Of Regents, The University Of Texas System Fabrication methods for nanodelivery systems for long term controlled delivery of active pharmaceutical ingredients
SG11202005947RA (en) 2018-05-24 2020-07-29 Celanese Eva Performance Polymers Corp Implantable device for sustained release of a macromolecular drug compound
WO2019226519A1 (en) 2018-05-24 2019-11-28 Celanese EVA Performance Polymers Corporation Implantable device for sustained release of a macromolecular drug compound
WO2019222856A1 (en) 2018-05-24 2019-11-28 Nureva Inc. Method, apparatus and computer-readable media to manage semi-constant (persistent) sound sources in microphone pickup/focus zones
EP3893884A4 (en) * 2018-12-11 2022-09-14 Lupin Inc. EXTREMELY LOW COMBINATION OF ESTROGEN COMBINATIONS DRUG DELIVERY SYSTEM, AND METHODS AND USES THEREOF
US10632066B1 (en) 2019-02-01 2020-04-28 The Population Council, Inc. Method of providing birth control
US10918649B2 (en) 2019-06-21 2021-02-16 The Population Council, Inc. System for providing birth control
US11529308B2 (en) 2019-06-21 2022-12-20 The Population Council, Inc. System for providing birth control
WO2021068239A1 (zh) 2019-10-12 2021-04-15 国家卫生健康委科学技术研究所 用于黄体支持的阴道缓释给药系统及其制备方法与应用
CN114980861A (zh) 2019-11-27 2022-08-30 橡冠科学研究院 缓释药物递送装置
USD935018S1 (en) 2020-04-07 2021-11-02 The Population Council, Inc. Contraceptive
WO2023133517A1 (en) 2022-01-06 2023-07-13 Oak Crest Institute Of Science Subdermal implant for sustained drug delivery
WO2024115763A1 (en) 2022-12-02 2024-06-06 Vari Bioscience Gmbh Estriol vaginal ring

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3040978A1 (de) * 1980-10-28 1982-05-27 Schering Ag, 1000 Berlin Und 4619 Bergkamen Vaginalring
ZA857643B (en) * 1984-10-12 1986-05-28 Akzo Nv Release system for two or more active substances
US4816258A (en) * 1987-02-26 1989-03-28 Alza Corporation Transdermal contraceptive formulations
ATE86484T1 (de) * 1987-08-08 1993-03-15 Akzo Nv Kontrazeptives implantat.
JPH03123727A (ja) * 1989-10-04 1991-05-27 Nitto Denko Corp 経皮吸収製剤
ES2166894T3 (es) * 1995-07-04 2002-05-01 Akzo Nobel Nv Dispositivos anulares.
US5906830A (en) * 1995-09-08 1999-05-25 Cygnus, Inc. Supersaturated transdermal drug delivery systems, and methods for manufacturing the same
IL123813A0 (en) * 1997-04-11 1998-10-30 Akzo Nobel Nv Drug delivery system for two or more active substances

Also Published As

Publication number Publication date
AU6075198A (en) 1998-10-15
CZ110298A3 (cs) 1998-10-14
DE69803112T2 (de) 2002-07-18
ATE211646T1 (de) 2002-01-15
KR19980081290A (ko) 1998-11-25
TW358031B (en) 1999-05-11
HU222343B1 (hu) 2003-06-28
PT876815E (pt) 2002-07-31
NO981638D0 (no) 1998-04-08
EP0876815A1 (en) 1998-11-11
IL123813A (en) 2001-11-25
ZA982911B (en) 1998-10-09
TR199800648A1 (xx) 1998-10-21
US5989581A (en) 1999-11-23
CA2233753C (en) 2001-12-25
SG65061A1 (en) 1999-05-25
DK0876815T3 (da) 2002-04-22
CN1163222C (zh) 2004-08-25
ID21259A (id) 1999-05-12
JP2009256378A (ja) 2009-11-05
AR011709A1 (es) 2000-08-30
CZ294099B6 (cs) 2004-10-13
BR9801027A (pt) 2000-01-11
NO981638L (no) 1998-10-12
ES2171283T3 (es) 2002-09-01
CN1196930A (zh) 1998-10-28
DE69803112D1 (de) 2002-02-14
JP4982670B2 (ja) 2012-07-25
BR9801027B1 (pt) 2009-01-13
PL325774A1 (en) 1998-10-12
HK1016886A1 (en) 1999-11-12
CA2233753A1 (en) 1998-10-11
EP0876815B1 (en) 2002-01-09
JPH10287549A (ja) 1998-10-27
PL192449B1 (pl) 2006-10-31
NZ330145A (en) 1999-05-28
RU2206325C2 (ru) 2003-06-20
HUP9800863A3 (en) 2000-06-28
IL123813A0 (en) 1998-10-30
HU9800863D0 (en) 1998-05-28
NO320394B1 (no) 2005-11-28
KR100492676B1 (ko) 2005-10-19
AU726934B2 (en) 2000-11-23

Similar Documents

Publication Publication Date Title
HUP9800863A2 (hu) Gyógyszerszállító rendszer két vagy több hatóanyaghoz
RU2176499C2 (ru) Композиция для чрескожного введения стероидных лекарственных средств и содержащий ее препарат
US5554381A (en) Low flux matrix system for delivering potent drugs transdermally
KR100561255B1 (ko) 호르몬 방출용 트랜스더멀 치료 시스템
JPS6470410A (en) Contraceptive implant
AU1227899A (en) Osmotic medicament releasing system
AR049112A1 (es) Composiciones, metodos y kit, para el tratamiento de trastorno disforico premenstrual
ATE290836T1 (de) Intravaginal-ringe mit einsetzbarem medikamentenenthaltenden kern
KR970069031A (ko) 당 제피로부터 스테로이드의 방출이 조절되는 약제학적 정제
HUP0402213A2 (hu) Propilénglikolmonokaprilátot tartalmazó szteroid hormontartalmú transzdermális terápiás rendszer
CY1115064T1 (el) Διαδερμικο συστημα παραδοσης ορμονων χωρις ενισχυτες διεισδυσης
EA200100108A1 (ru) Применение биогенных сульфаматов эстрогенов для гормонзаместительной терапии
PT1003477E (pt) Sistema terapeutico transdermico (tts), contendo polimeros de (met)acrilato com grupos amonio para administracao de levonorgestrel
EP1090639A3 (en) Pharmaceutical composition containing a progestational corticoid and a selective estrogen receptor modulator
EP1085858B1 (de) Transdermales therapeutisches system zur anwendung von candesartan
JPH09508911A (ja) デソゲストレルを含有する経皮適用剤
PL317996A1 (en) Carbamazepinic form of a drug with retarded release of biologically active substance
HUP0100542A2 (hu) Progesztogént és anti-progesztogént tartalmazó kit, eljárás előállítására és a vegyületek alkalmazása fogamzásgátló szer előállítására
HUP9901474A2 (hu) Szekvenciális ösztrogén/progeszteron-antagonista kombináció hormonhelyettesítő terápiához
DE59900775D1 (de) Ungesättigte 14,15-cyclopropano-androstane, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische präparate
TH55261B (th) การใช้ไบโอเจนิคอีสโตรเจนซัลฟาเมทในการรักษาการทดแทนฮอร์โมน
MXPA98002799A (en) System of delivery of medication for two or massubstancias acti
JP2002541076A (ja) 望ましくない子宮出血の処置に有用な鼻腔用医薬組成物を得るための性ホルモンの使用
BR0016092A (pt) Composto, uso de um composto kit para contracepção hormonal em um macho, e, método de tratamento

Legal Events

Date Code Title Description
HFG4 Patent granted, date of granting

Effective date: 20030407

GB9A Succession in title

Owner name: N.V. ORGANON, NL

Free format text: FORMER OWNER(S): AKZO NOBEL N.V., NL

GB9A Succession in title

Owner name: MSD OSS B.V., NL

Free format text: FORMER OWNER(S): AKZO NOBEL N.V., NL; N.V. ORGANON,, NL

GB9A Succession in title

Owner name: MERCK SHARP & DOHME B.V., NL

Free format text: FORMER OWNER(S): AKZO NOBEL N.V., NL; MSD OSS B.V., NL; N.V. ORGANON,, NL