DE69732312T8 - Schnellzerfallendes Granulate von einem synthetischen Süssstoff enthaltend Kieselsäure und/oder Siliciumdioxid - Google Patents

Schnellzerfallendes Granulate von einem synthetischen Süssstoff enthaltend Kieselsäure und/oder Siliciumdioxid Download PDF

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Publication number
DE69732312T8
DE69732312T8 DE69732312T DE69732312T DE69732312T8 DE 69732312 T8 DE69732312 T8 DE 69732312T8 DE 69732312 T DE69732312 T DE 69732312T DE 69732312 T DE69732312 T DE 69732312T DE 69732312 T8 DE69732312 T8 DE 69732312T8
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DE
Germany
Prior art keywords
silica
fast
synthetic sweetener
sweetener containing
disintegrating granules
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE69732312T
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German (de)
English (en)
Other versions
DE69732312T2 (de
DE69732312D1 (de
Inventor
Hisami Toyono-gun Yamaguchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Pharma Inc
Original Assignee
Astellas Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astellas Pharma Inc filed Critical Astellas Pharma Inc
Publication of DE69732312D1 publication Critical patent/DE69732312D1/de
Publication of DE69732312T2 publication Critical patent/DE69732312T2/de
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Publication of DE69732312T8 publication Critical patent/DE69732312T8/de
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Physiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Seasonings (AREA)
DE69732312T 1996-02-29 1997-02-21 Schnellzerfallendes Granulate von einem synthetischen Süssstoff enthaltend Kieselsäure und/oder Siliciumdioxid Active DE69732312T8 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP4274396 1996-02-29
JP4274396 1996-02-29
JP32026496 1996-11-29
JP32026496 1996-11-29

Publications (3)

Publication Number Publication Date
DE69732312D1 DE69732312D1 (de) 2005-02-24
DE69732312T2 DE69732312T2 (de) 2006-04-06
DE69732312T8 true DE69732312T8 (de) 2006-07-27

Family

ID=26382481

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69732312T Active DE69732312T8 (de) 1996-02-29 1997-02-21 Schnellzerfallendes Granulate von einem synthetischen Süssstoff enthaltend Kieselsäure und/oder Siliciumdioxid
DE69712332T Expired - Lifetime DE69712332T2 (de) 1996-02-29 1997-02-21 Beta-lactam-antibiotikum enthaltende tabletten und verfahren zu deren herstellung

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69712332T Expired - Lifetime DE69712332T2 (de) 1996-02-29 1997-02-21 Beta-lactam-antibiotikum enthaltende tabletten und verfahren zu deren herstellung

Country Status (23)

Country Link
US (4) US6423341B1 (https=)
EP (2) EP0890359B1 (https=)
JP (1) JP3180350B2 (https=)
KR (1) KR20040058360A (https=)
CN (2) CN1136853C (https=)
AR (1) AR006012A1 (https=)
AT (2) ATE216887T1 (https=)
AU (1) AU724946B2 (https=)
BR (1) BR9707780A (https=)
CA (1) CA2248179C (https=)
DE (2) DE69732312T8 (https=)
DK (2) DK0890359T3 (https=)
EA (1) EA001089B1 (https=)
ES (2) ES2173420T3 (https=)
HU (1) HU227821B1 (https=)
IL (1) IL125214A0 (https=)
MX (1) MX9806265A (https=)
NZ (2) NZ330864A (https=)
PT (2) PT1166651E (https=)
TR (1) TR199801680T2 (https=)
TW (1) TW473393B (https=)
WO (1) WO1997031639A1 (https=)
ZA (1) ZA971584B (https=)

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Also Published As

Publication number Publication date
DE69732312T2 (de) 2006-04-06
EP0890359A1 (en) 1999-01-13
KR20040058360A (ko) 2004-07-03
HU227821B1 (en) 2012-03-28
TW473393B (en) 2002-01-21
EA199800775A1 (ru) 1999-02-25
EA001089B1 (ru) 2000-10-30
HUP9901877A1 (hu) 1999-12-28
ZA971584B (en) 1997-09-10
MX9806265A (es) 1998-12-31
NZ512609A (en) 2003-03-28
DK0890359T3 (da) 2002-07-01
HUP9901877A3 (en) 2000-04-28
DE69732312D1 (de) 2005-02-24
US20030129227A1 (en) 2003-07-10
DE69712332D1 (de) 2002-06-06
DK1166651T3 (da) 2005-05-30
PT1166651E (pt) 2005-04-29
IL125214A0 (en) 1999-03-12
BR9707780A (pt) 1999-07-27
US20070134325A1 (en) 2007-06-14
US6423341B1 (en) 2002-07-23
CA2248179C (en) 2007-09-18
JP3180350B2 (ja) 2001-06-25
AU1734797A (en) 1997-09-16
EP1166651A1 (en) 2002-01-02
DE69712332T2 (de) 2002-10-02
CN1136853C (zh) 2004-02-04
PT890359E (pt) 2003-03-31
EP1166651B1 (en) 2005-01-19
AU724946B2 (en) 2000-10-05
US20020051816A1 (en) 2002-05-02
HK1015684A1 (en) 1999-10-22
ES2173420T3 (es) 2002-10-16
US20020192281A1 (en) 2002-12-19
EP0890359A4 (https=) 1999-01-13
NZ330864A (en) 2001-07-27
WO1997031639A1 (en) 1997-09-04
ATE287218T1 (de) 2005-02-15
ATE216887T1 (de) 2002-05-15
AR006012A1 (es) 1999-07-21
CN1409995A (zh) 2003-04-16
CA2248179A1 (en) 1997-09-04
TR199801680T2 (xx) 1999-02-22
EP0890359B1 (en) 2002-05-02
CN1212626A (zh) 1999-03-31
ES2231369T3 (es) 2005-05-16

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