DE69732312D1 - Schnellzerfallendes Granulate von einem synthetischen Süssstoff enthaltend Kieselsäure und/oder Siliciumdioxid - Google Patents

Schnellzerfallendes Granulate von einem synthetischen Süssstoff enthaltend Kieselsäure und/oder Siliciumdioxid

Info

Publication number
DE69732312D1
DE69732312D1 DE69732312T DE69732312T DE69732312D1 DE 69732312 D1 DE69732312 D1 DE 69732312D1 DE 69732312 T DE69732312 T DE 69732312T DE 69732312 T DE69732312 T DE 69732312T DE 69732312 D1 DE69732312 D1 DE 69732312D1
Authority
DE
Germany
Prior art keywords
silica
fast
synthetic sweetener
sweetener containing
disintegrating granules
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69732312T
Other languages
English (en)
Other versions
DE69732312T2 (de
DE69732312T8 (de
Inventor
Hisami Yamaguchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Pharma Inc
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of DE69732312D1 publication Critical patent/DE69732312D1/de
Publication of DE69732312T2 publication Critical patent/DE69732312T2/de
Application granted granted Critical
Publication of DE69732312T8 publication Critical patent/DE69732312T8/de
Active legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A61K31/546Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Seasonings (AREA)
DE69732312T 1996-02-29 1997-02-21 Schnellzerfallendes Granulate von einem synthetischen Süssstoff enthaltend Kieselsäure und/oder Siliciumdioxid Active DE69732312T8 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP4274396 1996-02-29
JP4274396 1996-02-29
JP32026496 1996-11-29
JP32026496 1996-11-29

Publications (3)

Publication Number Publication Date
DE69732312D1 true DE69732312D1 (de) 2005-02-24
DE69732312T2 DE69732312T2 (de) 2006-04-06
DE69732312T8 DE69732312T8 (de) 2006-07-27

Family

ID=26382481

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69712332T Expired - Lifetime DE69712332T2 (de) 1996-02-29 1997-02-21 Beta-lactam-antibiotikum enthaltende tabletten und verfahren zu deren herstellung
DE69732312T Active DE69732312T8 (de) 1996-02-29 1997-02-21 Schnellzerfallendes Granulate von einem synthetischen Süssstoff enthaltend Kieselsäure und/oder Siliciumdioxid

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69712332T Expired - Lifetime DE69712332T2 (de) 1996-02-29 1997-02-21 Beta-lactam-antibiotikum enthaltende tabletten und verfahren zu deren herstellung

Country Status (24)

Country Link
US (4) US6423341B1 (de)
EP (2) EP1166651B1 (de)
JP (1) JP3180350B2 (de)
KR (1) KR20040058360A (de)
CN (2) CN1136853C (de)
AR (1) AR006012A1 (de)
AT (2) ATE216887T1 (de)
AU (1) AU724946B2 (de)
BR (1) BR9707780A (de)
CA (1) CA2248179C (de)
DE (2) DE69712332T2 (de)
DK (2) DK1166651T3 (de)
EA (1) EA001089B1 (de)
ES (2) ES2231369T3 (de)
HK (1) HK1015684A1 (de)
HU (1) HU227821B1 (de)
IL (1) IL125214A0 (de)
MX (1) MX9806265A (de)
NZ (2) NZ512609A (de)
PT (2) PT890359E (de)
TR (1) TR199801680T2 (de)
TW (1) TW473393B (de)
WO (1) WO1997031639A1 (de)
ZA (1) ZA971584B (de)

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Also Published As

Publication number Publication date
EA199800775A1 (ru) 1999-02-25
AR006012A1 (es) 1999-07-21
CN1212626A (zh) 1999-03-31
NZ330864A (en) 2001-07-27
WO1997031639A1 (fr) 1997-09-04
EP0890359B1 (de) 2002-05-02
US20070134325A1 (en) 2007-06-14
BR9707780A (pt) 1999-07-27
US20020192281A1 (en) 2002-12-19
DK0890359T3 (da) 2002-07-01
CA2248179C (en) 2007-09-18
HUP9901877A1 (hu) 1999-12-28
KR20040058360A (ko) 2004-07-03
NZ512609A (en) 2003-03-28
ATE287218T1 (de) 2005-02-15
JP3180350B2 (ja) 2001-06-25
EA001089B1 (ru) 2000-10-30
CN1136853C (zh) 2004-02-04
DE69732312T2 (de) 2006-04-06
CA2248179A1 (en) 1997-09-04
ZA971584B (en) 1997-09-10
EP1166651A1 (de) 2002-01-02
ES2231369T3 (es) 2005-05-16
IL125214A0 (en) 1999-03-12
DK1166651T3 (da) 2005-05-30
ES2173420T3 (es) 2002-10-16
TR199801680T2 (xx) 1999-02-22
TW473393B (en) 2002-01-21
HU227821B1 (en) 2012-03-28
DE69712332T2 (de) 2002-10-02
DE69732312T8 (de) 2006-07-27
PT1166651E (pt) 2005-04-29
HUP9901877A3 (en) 2000-04-28
AU724946B2 (en) 2000-10-05
EP0890359A1 (de) 1999-01-13
MX9806265A (es) 1998-12-31
US20020051816A1 (en) 2002-05-02
DE69712332D1 (de) 2002-06-06
US6423341B1 (en) 2002-07-23
ATE216887T1 (de) 2002-05-15
EP0890359A4 (de) 1999-01-13
CN1409995A (zh) 2003-04-16
EP1166651B1 (de) 2005-01-19
PT890359E (pt) 2003-03-31
AU1734797A (en) 1997-09-16
HK1015684A1 (en) 1999-10-22
US20030129227A1 (en) 2003-07-10

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