DE69732312D1 - Schnellzerfallendes Granulate von einem synthetischen Süssstoff enthaltend Kieselsäure und/oder Siliciumdioxid - Google Patents

Schnellzerfallendes Granulate von einem synthetischen Süssstoff enthaltend Kieselsäure und/oder Siliciumdioxid

Info

Publication number
DE69732312D1
DE69732312D1 DE69732312T DE69732312T DE69732312D1 DE 69732312 D1 DE69732312 D1 DE 69732312D1 DE 69732312 T DE69732312 T DE 69732312T DE 69732312 T DE69732312 T DE 69732312T DE 69732312 D1 DE69732312 D1 DE 69732312D1
Authority
DE
Germany
Prior art keywords
silica
fast
synthetic sweetener
sweetener containing
disintegrating granules
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69732312T
Other languages
English (en)
Other versions
DE69732312T8 (de
DE69732312T2 (de
Inventor
Hisami Yamaguchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Pharma Inc
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of DE69732312D1 publication Critical patent/DE69732312D1/de
Application granted granted Critical
Publication of DE69732312T2 publication Critical patent/DE69732312T2/de
Publication of DE69732312T8 publication Critical patent/DE69732312T8/de
Active legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A61K31/546Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Physiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Seasonings (AREA)
DE69732312T 1996-02-29 1997-02-21 Schnellzerfallendes Granulate von einem synthetischen Süssstoff enthaltend Kieselsäure und/oder Siliciumdioxid Active DE69732312T8 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP4274396 1996-02-29
JP4274396 1996-02-29
JP32026496 1996-11-29
JP32026496 1996-11-29

Publications (3)

Publication Number Publication Date
DE69732312D1 true DE69732312D1 (de) 2005-02-24
DE69732312T2 DE69732312T2 (de) 2006-04-06
DE69732312T8 DE69732312T8 (de) 2006-07-27

Family

ID=26382481

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69732312T Active DE69732312T8 (de) 1996-02-29 1997-02-21 Schnellzerfallendes Granulate von einem synthetischen Süssstoff enthaltend Kieselsäure und/oder Siliciumdioxid
DE69712332T Expired - Lifetime DE69712332T2 (de) 1996-02-29 1997-02-21 Beta-lactam-antibiotikum enthaltende tabletten und verfahren zu deren herstellung

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69712332T Expired - Lifetime DE69712332T2 (de) 1996-02-29 1997-02-21 Beta-lactam-antibiotikum enthaltende tabletten und verfahren zu deren herstellung

Country Status (24)

Country Link
US (4) US6423341B1 (de)
EP (2) EP0890359B1 (de)
JP (1) JP3180350B2 (de)
KR (1) KR20040058360A (de)
CN (2) CN1136853C (de)
AR (1) AR006012A1 (de)
AT (2) ATE287218T1 (de)
AU (1) AU724946B2 (de)
BR (1) BR9707780A (de)
CA (1) CA2248179C (de)
DE (2) DE69732312T8 (de)
DK (2) DK1166651T3 (de)
EA (1) EA001089B1 (de)
ES (2) ES2173420T3 (de)
HK (1) HK1015684A1 (de)
HU (1) HU227821B1 (de)
IL (1) IL125214A0 (de)
MX (1) MX9806265A (de)
NZ (2) NZ330864A (de)
PT (2) PT890359E (de)
TR (1) TR199801680T2 (de)
TW (1) TW473393B (de)
WO (1) WO1997031639A1 (de)
ZA (1) ZA971584B (de)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6746105B2 (en) 1997-07-15 2004-06-08 Silverbrook Research Pty. Ltd. Thermally actuated ink jet printing mechanism having a series of thermal actuator units
US5948440A (en) * 1997-12-17 1999-09-07 Ranbaxy Laboratories Limited Modified release matrix formulation of cefaclor and cephalexin
AU3731699A (en) 1998-05-18 1999-12-06 Takeda Chemical Industries Ltd. Orally disintegrable tablets
AU4802099A (en) * 1998-07-28 2000-02-21 Takeda Chemical Industries Ltd. Rapidly disintegrable solid preparation
US20070160675A1 (en) * 1998-11-02 2007-07-12 Elan Corporation, Plc Nanoparticulate and controlled release compositions comprising a cephalosporin
US20080113025A1 (en) * 1998-11-02 2008-05-15 Elan Pharma International Limited Compositions comprising nanoparticulate naproxen and controlled release hydrocodone
PE20010635A1 (es) 1999-10-08 2001-08-15 Smithkline Beecham Corp Inhibidores de fab i utiles para el tratamiento de infecciones bacterianas
CA2311734C (en) * 2000-04-12 2011-03-08 Bristol-Myers Squibb Company Flash-melt oral dosage formulation
FR2814679B1 (fr) * 2000-09-29 2003-04-11 Cll Pharma Compositions pharmaceutiques dispersibles a base de cephalosporines, leur procede de preparation et leur utilisation
CA2444597A1 (en) * 2001-04-06 2002-10-06 Affinium Pharmaceuticals, Inc. Fab i inhibitors
GB0123400D0 (en) 2001-09-28 2001-11-21 Novartis Ag Organic compounds
GB0209265D0 (en) 2002-04-23 2002-06-05 Novartis Ag Organic compounds
JP4526247B2 (ja) * 2002-07-08 2010-08-18 第一三共株式会社 経口用セファロスポリン製剤
TW200404550A (en) * 2002-07-08 2004-04-01 Sankyo Co Cepharospolin formulation for oral use
EP1842852A1 (de) * 2002-08-13 2007-10-10 Sandoz AG Ein cefdinir-zwischenprodukt
US7790709B2 (en) 2002-12-06 2010-09-07 Affinium Pharmaceuticals, Inc. Heterocyclic compounds, methods of making them and their use in therapy
WO2004082586A2 (en) * 2003-03-17 2004-09-30 Affinium Pharmaceuticals, Inc. Phamaceutical compositions comprising inhibitors of fab i and further antibiotics
CN100357294C (zh) * 2003-03-24 2007-12-26 桑多斯股份公司 7-[2-(2-氨基噻唑-4-基)-2-羟基亚氨基乙酰胺-3-乙烯基-3-头孢烯-4-羧酸(顺式异构体)的新型晶体和其制备方法
WO2005013964A1 (ja) * 2003-08-08 2005-02-17 Ajinomoto Co., Inc. ナテグリニド含有製剤
US20050113355A1 (en) * 2003-09-12 2005-05-26 Duerst Richard W. Cefdinir pyridine salt
US20050059818A1 (en) * 2003-09-12 2005-03-17 Duerst Richard W. Polymorph of a pharmaceutical
US20050059819A1 (en) * 2003-09-12 2005-03-17 Duerst Richard W. Cefdinir pyridine salt
JP2005162696A (ja) * 2003-12-04 2005-06-23 Nichiko Pharmaceutical Co Ltd 溶出性に優れたセフジトレンピボキシル製剤
US20050131079A1 (en) * 2003-12-10 2005-06-16 Pujara Chetan P. Cefdinir oral suspension
US20080139528A1 (en) * 2003-12-10 2008-06-12 Pujara Chetan P Cefdinir oral suspension
US20060211676A1 (en) * 2004-03-16 2006-09-21 Devalina Law Crystalline anhydrous cefdinir and crystalline cefdinir hydrates
US20060142261A1 (en) * 2004-03-16 2006-06-29 Devalina Law Crystalline anhydrous cefdinir and crystalline cefdinir hydrates
US20060142563A1 (en) * 2004-03-16 2006-06-29 Devalina Law Crystalline anhydrous cefdinir and crystalline cefdinir hydrates
US20060069079A1 (en) * 2004-09-27 2006-03-30 Sever Nancy E Stable amorphous cefdinir
JP2007536378A (ja) * 2004-05-10 2007-12-13 ルピン・リミテッド 生体利用性が強化されている新規セフィキシム医薬製剤
WO2005115347A1 (en) * 2004-05-31 2005-12-08 Sam-A Pharmaceuticals Co., Ltd. Dispersible tablet comprising beta lactam antibiotics and process for preparing the same
EP2848614A3 (de) * 2004-06-04 2015-07-29 Debiopharm International SA Acrylamidderivate und ihre Verwendung als Antibiotika
US20060099253A1 (en) * 2004-10-20 2006-05-11 Wyeth Antibiotic product formulation
IL169678A (en) 2005-07-14 2010-11-30 Innova Sa Sweetener compositions
JP2009518399A (ja) * 2005-12-05 2009-05-07 アフィニウム ファーマシューティカルズ, インク. Fabi阻害剤および抗菌剤としてのヘテロ環アクリルアミド化合物
US20070128268A1 (en) * 2005-12-07 2007-06-07 Herwig Jennewein Pharmaceutical compositions comprising an antibiotic
WO2007125541A1 (en) * 2006-05-01 2007-11-08 Lupin Limited Pharmaceutical compositions of cefdinir
WO2008009122A1 (en) 2006-07-20 2008-01-24 Affinium Pharmaceuticals, Inc. Acrylamide derivatives as fab i inhibitors
JP5274261B2 (ja) * 2006-12-07 2013-08-28 第一三共株式会社 低置換度ヒドロキシプロピルセルロースを含有する医薬組成物
JP5289975B2 (ja) * 2006-12-07 2013-09-11 第一三共株式会社 マンニトール又は乳糖を含有する固形製剤
TWI405591B (zh) * 2006-12-07 2013-08-21 Daiichi Sankyo Co Ltd 固形製劑之製造方法
WO2008098374A1 (en) * 2007-02-16 2008-08-21 Affinium Pharmaceuticals, Inc. Salts, prodrugs and polymorphs of fab i inhibitors
TR200909786A1 (tr) 2009-12-25 2011-07-21 Bi̇lgi̇ç Mahmut Sefiksim içeren efervesan tablet ve granül formülasyonu.
TR200909785A1 (tr) * 2009-12-25 2011-07-21 Bi̇lgi̇ç Mahmut Aktif ajan olarak sefdinir içeren farmasötik kompozisyonlar.
US8614315B2 (en) 2009-12-25 2013-12-24 Mahmut Bilgic Cefdinir and cefixime formulations and uses thereof
EP2515859B1 (de) * 2009-12-25 2015-09-16 Mahmut Bilgic Schnell dispergierende brauseformulierung
TR201000686A1 (tr) * 2010-01-29 2011-08-22 B�Lg�� Mahmut Bakteriyel enfeksiyonların tedavisinde suda çözünebilir sefdinir ve klavulanik asit formülasyonları.@
TR201000687A1 (tr) * 2010-01-29 2011-08-22 Bi̇lgi̇ç Mahmut Aktif madde olarak sefiksim ve klavulanik asit içeren efervesan formülasyonlar
TR201001417A1 (tr) * 2010-02-25 2011-09-21 Sanovel İlaç San. Ve Ti̇c. A. Ş. Geliştirilmiş çözünme hızına sahip sefdinir formülasyonu
WO2011142731A2 (en) * 2010-05-14 2011-11-17 Mahmut Bilgic Formulations comprising a third generation cephalosporin and clavulanic acid
WO2011139252A2 (en) * 2010-05-04 2011-11-10 Mahmut Bilgic Efervescent formulations comprising cefdinir
EA021874B1 (ru) * 2010-09-13 2015-09-30 ЛИМОНОВ, Виктор Львович Фармацевтическая композиция антимикробного действия для парентерального введения и способ ее получения
TR201009166A2 (tr) * 2010-11-05 2012-05-21 Bi̇lgi̇ç Mahmut Sefdinir içeren farmasötik bileşim için üretim yöntemi
TR201010212A2 (tr) * 2010-12-08 2012-06-21 Bi̇lgi̇ç Mahmut Sefdinir içeren katı oral dozaj formu.
AU2013279021C1 (en) 2012-06-19 2017-03-16 Debiopharm International Sa Prodrug derivatives of (E)-N-methyl-N-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide
WO2014051532A1 (en) * 2012-09-28 2014-04-03 Bilgic Mahmut Pharmaceutical tablet formulations comprising cefdinir
TR201802828T4 (tr) * 2012-10-02 2018-03-21 Montero Gida Sanayi Ve Ticaret Anonim Sirketi Mogrosid formülasyonu ve üretim prosesi.
EP2906203B1 (de) 2012-10-11 2018-01-03 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Brauseformulierung von cefdinir
EP2815743A1 (de) 2013-06-21 2014-12-24 Sanovel Ilac Sanayi ve Ticaret A.S. Formulierungen mit Ceftibuten
US20160242439A1 (en) 2014-04-04 2016-08-25 Douxmatok Ltd Method for producing sweetener compositions and sweetener compositions
US10231476B2 (en) 2014-04-04 2019-03-19 Douxmatok Ltd Sweetener compositions and foods, beverages, and consumable products made thereof
US10207004B2 (en) 2014-04-04 2019-02-19 Douxmatok Ltd Method for producing sweetener compositions and sweetener compositions
KR20180114177A (ko) 2016-02-26 2018-10-17 데비오팜 인터네셔날 에스 에이 당뇨병성 족부 감염의 치료제
CN115607514B (zh) * 2021-07-16 2023-12-12 广州白云山天心制药股份有限公司 一种含有头孢地尼颗粒的制备方法

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3098749A (en) * 1960-11-16 1963-07-23 Abbott Lab Sweetening agent and process of producing the same
US3336199A (en) * 1963-07-03 1967-08-15 Warner Lambert Pharmaceutical Tablet composition
DE2251250C3 (de) * 1972-10-19 1981-06-25 Hoechst Ag, 6230 Frankfurt Verfahren zur Herstellung hochdosierter Antibiotica-Tabletten
US4039673A (en) * 1973-10-30 1977-08-02 Bayer Aktiengesellschaft Penicillins and cephalosporins and their production
JPS5438167B2 (de) * 1974-04-27 1979-11-19
US4248894A (en) * 1979-01-17 1981-02-03 Life Savers, Inc. Long-lasting flavored chewing gum containing non-sugar sweetener codried on chalk or other filler and method
US4384005A (en) * 1980-09-26 1983-05-17 General Foods Corporation Non-friable, readily-soluble, compressed tablets and process for preparing same
JPS57150361A (en) * 1981-03-10 1982-09-17 Ajinomoto Co Inc Granule of dipeptide sweetener
US4352821A (en) * 1981-07-21 1982-10-05 Shaklee Corporation Sweet tableting agent
EP0080862B1 (de) * 1981-12-02 1985-09-25 Beecham Group Plc Pharmazeutische Zubereitung die Beta-Lactam Antibiotika enthält
JPS58198268A (ja) * 1982-05-14 1983-11-18 Ajinomoto Co Inc 甘味料顆粒又はキユ−ブの製造法
US4600579A (en) * 1983-06-07 1986-07-15 Mallinckrodt, Inc. N-acetyl-p-aminophenol compositions containing partially gelatinized starch and method for preparing same
US4752485A (en) * 1984-10-05 1988-06-21 Warner-Lambert Company Novel sweetener delivery systems
US4722845A (en) * 1986-12-23 1988-02-02 Warner-Lambert Company Stable cinnamon-flavored chewing gum composition
DE3887179T2 (de) * 1987-03-02 1994-06-16 Brocades Pharma Bv Pharmazeutische Zusammensetzung, pharmazeutisches Granulat und Verfahren zu ihrer Herstellung.
US4915948A (en) * 1987-08-31 1990-04-10 Warner-Lambert Company Tablets having improved bioadhesion to mucous membranes
JPH01206969A (ja) * 1987-10-30 1989-08-21 Takeda Chem Ind Ltd 甘味料顆粒の製造法
JPH01149728A (ja) * 1987-12-04 1989-06-12 Fujisawa Pharmaceut Co Ltd 抗潰瘍剤
FR2634355B1 (fr) * 1988-07-25 1990-09-14 Beghin Say Sa Nouveau produit edulcorant alimentaire a base de saccharose et d'edulcorant intense et son procede de preparation
US5085876A (en) * 1988-11-16 1992-02-04 The Nutrasweet Company Fast dissolving sweetening agent including caramel
US5114929A (en) * 1989-03-21 1992-05-19 Beecham Group P.L.C. Pharmaceutical formulation
FR2669221B1 (fr) * 1990-11-15 1993-01-15 Rhone Poulenc Sante Procede de preparation par compression directe de comprimes de derives de l'acide cephalosporanique.
GB9109862D0 (en) * 1991-05-08 1991-07-03 Beecham Lab Sa Pharmaceutical formulations
ATE216577T1 (de) * 1992-01-29 2002-05-15 Takeda Chemical Industries Ltd Schnellösliche tablette und ihre herstellung
ES2059260B1 (es) * 1992-10-06 1995-04-16 Espanola Prod Quimicos Procedimiento de preparacion de comprimidos conteniendo diclofenaco; dispersables en agua.
JP3063438B2 (ja) * 1992-12-24 2000-07-12 田辺製薬株式会社 ドパミン誘導体含有経口投与用製剤
EP0711554A4 (de) * 1993-07-28 1997-07-23 Nippon Shinyaku Co Ltd Antidepressivum
DE4418957A1 (de) * 1994-05-31 1995-12-07 Merck Patent Gmbh Cefixim-Zubereitung
JP2994956B2 (ja) * 1994-05-31 1999-12-27 信越化学工業株式会社 低置換度ヒドロキシプロピルセルロース、その組成物およびその錠剤
ES2082723B1 (es) * 1994-07-20 1996-10-01 Lilly Sa Formulacion farmaceutica de fluoxetina en forma dispersable.
FR2722984B1 (fr) * 1994-07-26 1996-10-18 Effik Lab Procede de preparation de formes pharmaceutiques seches et les compositions pharmaceutiques ainsi realisees
ES2079327B1 (es) * 1994-12-13 1996-08-01 Lilly Sa Formulaciones farmaceuticas de cefaclor.

Also Published As

Publication number Publication date
HUP9901877A3 (en) 2000-04-28
JP3180350B2 (ja) 2001-06-25
EP1166651B1 (de) 2005-01-19
US20070134325A1 (en) 2007-06-14
EP0890359A4 (de) 1999-01-13
US20030129227A1 (en) 2003-07-10
CN1409995A (zh) 2003-04-16
PT890359E (pt) 2003-03-31
DK0890359T3 (da) 2002-07-01
ATE216887T1 (de) 2002-05-15
TW473393B (en) 2002-01-21
US20020192281A1 (en) 2002-12-19
CA2248179A1 (en) 1997-09-04
HU227821B1 (en) 2012-03-28
CN1212626A (zh) 1999-03-31
DE69712332D1 (de) 2002-06-06
DE69712332T2 (de) 2002-10-02
HK1015684A1 (en) 1999-10-22
DE69732312T8 (de) 2006-07-27
ZA971584B (en) 1997-09-10
CA2248179C (en) 2007-09-18
EP1166651A1 (de) 2002-01-02
ES2173420T3 (es) 2002-10-16
CN1136853C (zh) 2004-02-04
US6423341B1 (en) 2002-07-23
AR006012A1 (es) 1999-07-21
BR9707780A (pt) 1999-07-27
ATE287218T1 (de) 2005-02-15
WO1997031639A1 (fr) 1997-09-04
AU1734797A (en) 1997-09-16
EA199800775A1 (ru) 1999-02-25
IL125214A0 (en) 1999-03-12
AU724946B2 (en) 2000-10-05
DK1166651T3 (da) 2005-05-30
EP0890359B1 (de) 2002-05-02
US20020051816A1 (en) 2002-05-02
MX9806265A (es) 1998-12-31
DE69732312T2 (de) 2006-04-06
NZ330864A (en) 2001-07-27
KR20040058360A (ko) 2004-07-03
EP0890359A1 (de) 1999-01-13
TR199801680T2 (xx) 1999-02-22
EA001089B1 (ru) 2000-10-30
NZ512609A (en) 2003-03-28
ES2231369T3 (es) 2005-05-16
HUP9901877A1 (hu) 1999-12-28
PT1166651E (pt) 2005-04-29

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