HUP9901877A1 - Béta-laktám antibiotikumot tartalmazó tabletták és eljárás előállításukra - Google Patents

Béta-laktám antibiotikumot tartalmazó tabletták és eljárás előállításukra

Info

Publication number
HUP9901877A1
HUP9901877A1 HU9901877A HUP9901877A HUP9901877A1 HU P9901877 A1 HUP9901877 A1 HU P9901877A1 HU 9901877 A HU9901877 A HU 9901877A HU P9901877 A HUP9901877 A HU P9901877A HU P9901877 A1 HUP9901877 A1 HU P9901877A1
Authority
HU
Hungary
Prior art keywords
lactam antibiotic
béta
producing
same
tablets containing
Prior art date
Application number
HU9901877A
Other languages
English (en)
Inventor
Hisami Yamaguchi
Original Assignee
Fujisawa Pharmaceutical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co., Ltd. filed Critical Fujisawa Pharmaceutical Co., Ltd.
Publication of HUP9901877A1 publication Critical patent/HUP9901877A1/hu
Publication of HUP9901877A3 publication Critical patent/HUP9901877A3/hu
Publication of HU227821B1 publication Critical patent/HU227821B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Physiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Seasonings (AREA)

Abstract

A találmány tárgyát -laktám antibiőtikűmőt tartalmazó tablettákképezik, amelyek őrálisan bevehetők, kis méretűek, könnyűnyelhetőségük miatt nyelési prőblémában szenvedő időseknélalkalmazható diszperziós főrmában, mivel könnyen önmagűktól szétesnekegy pőhár vízbe vagy főlyadékba történő bedőbásűkkőr, valamint atalálmány tárgykörébe tartőzik az ilyen tabletták előállítása is. Ajelen találmány tablettái tablettánként 60-85 súly% -laktámantibiőtikűmőt, dezintegrátőrként 1-10 súly% kismértékbenszűbsztitűált hidrőxi-prőpil-cellűlózt, és/vagy keresztkötöttpőlivinilpirrőlidőnt és 0,5-2 súly% kötőanyagőt tartalmaznak. Atablettázáshőz a szemcséket vízzel vagy vizes etanőlőldattal, vagyhasőnlóval készítik. ŕ
HU9901877A 1996-02-29 1997-02-21 Tablets containing beta-lactam antibiotic and process for producing the same HU227821B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP4274396 1996-02-29
JP32026496 1996-11-29
PCT/JP1997/000509 WO1997031639A1 (fr) 1996-02-29 1997-02-21 COMPRIMES CONTENANT UN ANTIBIOTIQUE AU β-LACTAME ET PROCEDE POUR LEUR PRODUCTION

Publications (3)

Publication Number Publication Date
HUP9901877A1 true HUP9901877A1 (hu) 1999-12-28
HUP9901877A3 HUP9901877A3 (en) 2000-04-28
HU227821B1 HU227821B1 (en) 2012-03-28

Family

ID=26382481

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9901877A HU227821B1 (en) 1996-02-29 1997-02-21 Tablets containing beta-lactam antibiotic and process for producing the same

Country Status (24)

Country Link
US (4) US6423341B1 (hu)
EP (2) EP1166651B1 (hu)
JP (1) JP3180350B2 (hu)
KR (1) KR20040058360A (hu)
CN (2) CN1136853C (hu)
AR (1) AR006012A1 (hu)
AT (2) ATE216887T1 (hu)
AU (1) AU724946B2 (hu)
BR (1) BR9707780A (hu)
CA (1) CA2248179C (hu)
DE (2) DE69732312T8 (hu)
DK (2) DK0890359T3 (hu)
EA (1) EA001089B1 (hu)
ES (2) ES2173420T3 (hu)
HK (1) HK1015684A1 (hu)
HU (1) HU227821B1 (hu)
IL (1) IL125214A0 (hu)
MX (1) MX9806265A (hu)
NZ (2) NZ330864A (hu)
PT (2) PT890359E (hu)
TR (1) TR199801680T2 (hu)
TW (1) TW473393B (hu)
WO (1) WO1997031639A1 (hu)
ZA (1) ZA971584B (hu)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA021874B1 (ru) * 2010-09-13 2015-09-30 ЛИМОНОВ, Виктор Львович Фармацевтическая композиция антимикробного действия для парентерального введения и способ ее получения

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DE69712332D1 (de) 2002-06-06
CN1212626A (zh) 1999-03-31
KR20040058360A (ko) 2004-07-03
PT1166651E (pt) 2005-04-29
NZ330864A (en) 2001-07-27
NZ512609A (en) 2003-03-28
BR9707780A (pt) 1999-07-27
JP3180350B2 (ja) 2001-06-25
US20020051816A1 (en) 2002-05-02
EP1166651A1 (en) 2002-01-02
IL125214A0 (en) 1999-03-12
EP1166651B1 (en) 2005-01-19
EA199800775A1 (ru) 1999-02-25
EP0890359A4 (hu) 1999-01-13
TW473393B (en) 2002-01-21
DE69732312D1 (de) 2005-02-24
CN1409995A (zh) 2003-04-16
DK1166651T3 (da) 2005-05-30
CA2248179A1 (en) 1997-09-04
EP0890359B1 (en) 2002-05-02
ATE216887T1 (de) 2002-05-15
DE69732312T2 (de) 2006-04-06
US6423341B1 (en) 2002-07-23
AR006012A1 (es) 1999-07-21
TR199801680T2 (xx) 1999-02-22
ES2173420T3 (es) 2002-10-16
ZA971584B (en) 1997-09-10
DE69712332T2 (de) 2002-10-02
CN1136853C (zh) 2004-02-04
CA2248179C (en) 2007-09-18
EP0890359A1 (en) 1999-01-13
US20070134325A1 (en) 2007-06-14
DK0890359T3 (da) 2002-07-01
ATE287218T1 (de) 2005-02-15
AU724946B2 (en) 2000-10-05
HUP9901877A3 (en) 2000-04-28
MX9806265A (es) 1998-12-31
US20030129227A1 (en) 2003-07-10
AU1734797A (en) 1997-09-16
HK1015684A1 (en) 1999-10-22
ES2231369T3 (es) 2005-05-16
HU227821B1 (en) 2012-03-28
WO1997031639A1 (fr) 1997-09-04
EA001089B1 (ru) 2000-10-30
PT890359E (pt) 2003-03-31
DE69732312T8 (de) 2006-07-27
US20020192281A1 (en) 2002-12-19

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